Inflammation and cancer: triggers, mechanisms, and consequences

Hallmarks of Cancer: The Next Generation

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PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer

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Cancer-related inflammation

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Immunity, Inflammation, and Cancer

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Origin and physiological roles of inflammation

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Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion

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Understanding the tumor immune microenvironment (TIME) for effective therapy

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The future of immune checkpoint therapy

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Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

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Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

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STATs in cancer inflammation and immunity: a leading role for STAT3

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Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

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NF-κB: linking inflammation and immunity to cancer development and progression

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The Three Es of Cancer Immunoediting

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Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

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Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

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Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

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Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

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Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin

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Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

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IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

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Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab

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Intestinal inflammation targets cancer-inducing activity of the microbiota

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Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy

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Crypt stem cells as the cells-of-origin of intestinal cancer

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IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

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Natural Innate and Adaptive Immunity to Cancer

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Targeting macrophages: therapeutic approaches in cancer

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Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

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Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

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Myeloid-Derived Suppressor Cells

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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

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Myeloid-derived suppressor cells coming of age

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IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

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Radical causes of cancer

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Analysis of <i>Fusobacterium</i> persistence and antibiotic response in colorectal cancer

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Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

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Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials

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Identification of the tumour transition states occurring during EMT

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Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species

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Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice

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Adaptive immunity maintains occult cancer in an equilibrium state

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A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

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IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma

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Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

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Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

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CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

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Interactions between cancer stem cells and their niche govern metastatic colonization

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Adenoma–linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

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Macrophage polarization in tumour progression

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Neutrophils escort circulating tumour cells to enable cell cycle progression

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Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer

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Intestinal Inflammation and Cancer

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Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

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Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

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Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

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Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

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Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability

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Necroptosis in development, inflammation and disease

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Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials

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Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

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Neoantigen-directed immune escape in lung cancer evolution

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Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

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Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets

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Blocking TNF-α in mice reduces colorectal carcinogenesis associated with chronic colitis

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IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

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Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression

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A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer

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Fatty acid transport protein 2 reprograms neutrophils in cancer

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TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling

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IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

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Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

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Ionic immune suppression within the tumour microenvironment limits T cell effector function

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Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

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Senescent cells as a source of inflammatory factors for tumor progression

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The Human Gut Bacterial Genotoxin Colibactin Alkylates DNA

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Tissue biology perspective on macrophages

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