CoChat
Sign Up
Cited by 250

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue

Zhao, Peng, Wong, Kai in, Sun, Xiaoli, Reilly, Shannon M., Uhm, Maeran, Liao, Zhongji, Skorobogatko, Yuliya, Saltiel, Alan R.·2018·Cell
DOI 10.1016/j.cell.2018.01.007PMC PMC5808582
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.cell.2018.01.007

Cites

17 of 17 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 17 references

Research works printed but not linked: 52

  1. Bachman, 2002, betaAR signaling required for diet-induced thermogenesis and obesity resistance, Science, 297, 843, 10.1126/science.1073160 · DOI
  2. Baker, 2011, NF-κB, inflammation, and metabolic disease, Cell Metab., 13, 11, 10.1016/j.cmet.2010.12.008 · DOI · Paper page
  3. Cantó, 2009, PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure, Curr. Opin. Lipidol., 20, 98, 10.1097/MOL.0b013e328328d0a4 · DOI · Paper page
  4. Cantó, 2011, Calorie restriction: is AMPK a key sensor and effector?, Physiology (Bethesda), 26, 214
  5. Cauwels, 2014, Extracellular ATP drives systemic inflammation, tissue damage and mortality, Cell Death Dis., 5, e1102, 10.1038/cddis.2014.70 · DOI
  6. Chiang, 2009, The protein kinase IKKepsilon regulates energy balance in obese mice, Cell, 138, 961, 10.1016/j.cell.2009.06.046 · DOI
  7. Choi, 2015, Br. J. Nutr., 113, 867, 10.1017/S0007114515000100 · DOI
  8. Clément, 2008, The IKK-related kinases: from innate immunity to oncogenesis, Cell Res., 18, 889, 10.1038/cr.2008.273 · DOI
  9. Coleman, 1978, Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice, Diabetologia, 14, 141, 10.1007/BF00429772 · DOI · Paper page
  10. Daval, 2006, Functions of AMP-activated protein kinase in adipose tissue, J. Physiol., 574, 55, 10.1113/jphysiol.2006.111484 · DOI
  11. Delhase, 2012, TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2, Proc. Natl. Acad. Sci. USA, 109, E177, 10.1073/pnas.1119296109 · DOI
  12. Garcia-Haro, 2010, The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 beta cells, FASEB J., 24, 5080
  13. Gauthier, 2011, Decreased AMP-activated protein kinase activity is associated with increased inflammation in visceral adipose tissue and with whole-body insulin resistance in morbidly obese humans, Biochem. Biophys. Res. Commun., 404, 382, 10.1016/j.bbrc.2010.11.127 · DOI
  14. Hall, 2012, Energy balance and its components: implications for body weight regulation, Am. J. Clin. Nutr., 95, 989, 10.3945/ajcn.112.036350 · DOI · Paper page
  15. Hardie, 2011, AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function, Genes Dev., 25, 1895, 10.1101/gad.17420111 · DOI · Paper page
  16. Hawley, 2014, Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells, Biochem. J., 459, 275, 10.1042/BJ20131344 · DOI
  17. Hotamisligil, 1993, Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance, Science, 259, 87, 10.1126/science.7678183 · DOI · Paper page
  18. Hotamisligil, 1994, Tumor necrosis factor alpha inhibits signaling from the insulin receptor, Proc. Natl. Acad. Sci. USA, 91, 4854, 10.1073/pnas.91.11.4854 · DOI
  19. Hotamisligil, 1996, IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance, Science, 271, 665, 10.1126/science.271.5249.665 · DOI · Paper page
  20. Huang, 2015, AMPK activation inhibits expression of proinflammatory mediators through downregulation of PI3K/p38 MAPK and NF-κB signaling in murine macrophages, DNA Cell Biol., 34, 133, 10.1089/dna.2014.2630 · DOI
  21. Jeffery, 2014, Characterization of Cre recombinase models for the study of adipose tissue, Adipocyte, 3, 206, 10.4161/adip.29674 · DOI
  22. Kamei, 2006, Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance, J. Biol. Chem., 281, 26602, 10.1074/jbc.M601284200 · DOI
  23. Kazak, 2015, A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat, Cell, 163, 643, 10.1016/j.cell.2015.09.035 · DOI · Paper page
  24. Kazak, 2017, Genetic depletion of adipocyte creatine metabolism inhibits diet-induced thermogenesis and drives obesity, Cell Metab., 26, 660, 10.1016/j.cmet.2017.08.009 · DOI
  25. Larson-Meyer, 2006, Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects, Diabetes Care, 29, 1337, 10.2337/dc05-2565 · DOI · Paper page
  26. Lawrence, 2009, The nuclear factor NF-kappaB pathway in inflammation, Cold Spring Harb. Perspect. Biol., 1, a001651, 10.1101/cshperspect.a001651 · DOI
  27. Lohman, 2015, Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation, Nat. Commun., 6, 7965, 10.1038/ncomms8965 · DOI
  28. Ma, 2012, Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation, Proc. Natl. Acad. Sci. USA, 109, 9378, 10.1073/pnas.1121552109 · DOI
  29. Martin, 2006, Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle, J. Biol. Chem., 281, 18933, 10.1074/jbc.M512831200 · DOI
  30. Mottillo, 2016, Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function, Cell Metab., 24, 118, 10.1016/j.cmet.2016.06.006 · DOI
  31. Mowers, 2013, Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKε and TBK1, eLife, 2, e01119, 10.7554/eLife.01119 · DOI
  32. O’Neill, 2013, Metabolism of inflammation limited by AMPK and pseudo-starvation, Nature, 493, 346, 10.1038/nature11862 · DOI · Paper page
  33. Oral, 2017, Inhibition of IKKε and TBK1 improves glucose control in a subset of patients with type 2 diabetes, Cell Metab., 26, 157, 10.1016/j.cmet.2017.06.006 · DOI
  34. Pazos, 2015, Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice, Sci. Rep., 5, 17977, 10.1038/srep17977 · DOI · Paper page
  35. Perry, 2004, Differential requirement for TANK-binding kinase-1 in type I interferon responses to toll-like receptor activation and viral infection, J. Exp. Med., 199, 1651, 10.1084/jem.20040528 · DOI
  36. Puigserver, 1998, A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis, Cell, 92, 829, 10.1016/S0092-8674(00)81410-5 · DOI · Paper page
  37. Rasmussen, 2007, Effect on 24-h energy expenditure of a moderate-fat diet high in monounsaturated fatty acids compared with that of a low-fat, carbohydrate-rich diet: a 6-mo controlled dietary intervention trial, Am. J. Clin. Nutr., 85, 1014, 10.1093/ajcn/85.4.1014 · DOI
  38. Ravussin, 1988, Reduced rate of energy expenditure as a risk factor for body-weight gain, N. Engl. J. Med., 318, 467, 10.1056/NEJM198802253180802 · DOI · Paper page
  39. Reilly, 2017, Adapting to obesity with adipose tissue inflammation, Nat. Rev. Endocrinol., 13, 633, 10.1038/nrendo.2017.90 · DOI · Paper page
  40. Reilly, 2013, An inhibitor of the protein kinases TBK1 and IKK-ε improves obesity-related metabolic dysfunctions in mice, Nat. Med., 19, 313, 10.1038/nm.3082 · DOI
  41. Reznick, 2006, The role of AMP-activated protein kinase in mitochondrial biogenesis, J. Physiol., 574, 33, 10.1113/jphysiol.2006.109512 · DOI
  42. Roberts, 1998, Excess energy intake and low energy expenditure as predictors of obesity, Int. J. Obes. Relat. Metab. Disord., 22, 385, 10.1038/sj.ijo.0800640 · DOI
  43. Russell, 2013, ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase, Nat. Cell Biol., 15, 741, 10.1038/ncb2757 · DOI · Paper page
  44. Salminen, 2011, AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan, J. Mol. Med. (Berl.), 89, 667, 10.1007/s00109-011-0748-0 · DOI · Paper page
  45. Schnurr, 2000, Extracellular ATP and TNF-alpha synergize in the activation and maturation of human dendritic cells, J. Immunol., 165, 4704, 10.4049/jimmunol.165.8.4704 · DOI
  46. Sun, 2011, Non-canonical NF-κB signaling pathway, Cell Res., 21, 71, 10.1038/cr.2010.177 · DOI
  47. Suzuki, 2013, Inhibition of AMPK catabolic action by GSK3, Mol. Cell, 50, 407, 10.1016/j.molcel.2013.03.022 · DOI
  48. Wan, 2014, Evidence for the role of AMPK in regulating PGC-1 alpha expression and mitochondrial proteins in mouse epididymal adipose tissue, Obesity (Silver Spring), 22, 730, 10.1002/oby.20605 · DOI
  49. Wu, 1999, Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1, Cell, 98, 115, 10.1016/S0092-8674(00)80611-X · DOI · Paper page
  50. Xu, 2012, Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue, J. Lipid Res., 53, 792, 10.1194/jlr.P022905 · DOI
  51. Zarnegar, 2008, Control of canonical NF-kappaB activation through the NIK-IKK complex pathway, Proc. Natl. Acad. Sci. USA, 105, 3503, 10.1073/pnas.0707959105 · DOI
  52. Zhao, 2013, STAT1, NF-κB and ERKs play a role in the induction of lipocalin-2 expression in adipocytes, Mol. Metab., 2, 161, 10.1016/j.molmet.2013.04.003 · DOI

Cited by

Sorted by citations

Metadata

Authors
Zhao, P., Wong, K. I., Sun, X., Reilly, S. M., Uhm, M., Liao, Z., Skorobogatko, Y., & Saltiel, A. R.
Venue
Cell
Publisher
Elsevier BV
Published
2018-02
Volume
172
Issue
4
Pages
731-743.e12
ISSN
0092-8674
DOI
10.1016/j.cell.2018.01.007
PMC
PMC5808582
Cited by
250
References
17
Language
en
Licence
Funders
National Institutes of Health (R01DK100319, R01DK60591, R01DK60597, P30DK06349)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review