Toll-like Receptors and the Control of Immunity

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., Zhuang, Y., Cai, T., Wang, F., & Shao, F. (2015) · Nature · doi:10.1038/nature15514 · Cited by 6,659

Origin and physiological roles of inflammation

Medzhitov, R. (2008) · Nature · doi:10.1038/nature07201 · Cited by 6,618

A Toll-like receptor recognizes bacterial DNA

Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) · Nature · doi:10.1038/35047123 · Cited by 6,491

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Medzhitov, R., Preston-Hurlburt, P., & Janeway, C. A. J. (1997) · Nature · doi:10.1038/41131 · Cited by 6,137

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature · doi:10.1038/35099560 · Cited by 6,129

The Inflammasome

Martinon, F., Burns, K., & Tschopp, J. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00599-3 · Cited by 6,066

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Sun, L., Wu, J., Du, F., Chen, X., & Chen, Z. J. (2013) · Science · doi:10.1126/science.1232458 · Cited by 4,996

Mutations affecting segment number and polarity in Drosophila

Nüsslein‐Volhard, C., & Wieschaus, E. F. (1980) · Nature · doi:10.1038/287795a0 · Cited by 4,370

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Lemaître, B., Nicolas, E., Michaut, L., Reichhart, J., & Hoffmann, J. A. (1996) · Cell · doi:10.1016/s0092-8674(00)80172-5 · Cited by 4,224

Noncanonical autophagy is a new strategy to inhibit HSV-1 through STING1 activation

Zheng, Z., Zhao, M., Shan, H., Fang, D., Jin, Z., Tang, J., Liu, Z., Hong, L., Liu, P., & Li, M. (2023) · Autophagy · doi:10.1080/15548627.2023.2237794 · Cited by 30

Helenine blocks NLRP3 activation by disrupting the NEK7-NLRP3 interaction and ameliorates inflammatory diseases

Fang, Z.-E., Wang, Y., Qin, S., Qin, S., Zhao, H., Wen, J., Liu, T., Ren, L., Li, Q., Shi, W., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.155159 · Cited by 33

Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6

Zhang, X., He, Y., Zhang, X., Fu, B., Song, Z., Wang, L., Fu, R., Lu, X., Jin, X. Y., Lv, J., et al. (2024) · Gastric Cancer · doi:10.1007/s10120-023-01461-7 · Cited by 31

Role of pattern recognition receptors in the development of MASLD and potential therapeutic applications

Yu, L., Gao, F., Li, Y., Su, D., Han, L., Li, Y., Zhang, X., & Feng, Z. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116724 · Cited by 39

Epithelial cell membrane perforation induces allergic airway inflammation

Shi, K., Lv, Y., Zhao, C., Zeng, H., Wang, Y., Liu, Y., Li, L., Chen, S., Gao, P., Shao, F., et al. (2025) · Nature · doi:10.1038/s41586-025-09331-1 · Cited by 32

Nucleic Acid-Sensing Pathways During SARS-CoV-2 Infection: Expectations versus Reality

Mdkhana, B., Sharif‐Askari, N. S., Ramakrishnan, R. K., Goel, S., Hamid, Q. A., & Halwani, R. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s277716 · Cited by 31

CRISPR-based functional genomics in human dendritic cells

Jost, M., Jacobson, A. N., Hussmann, J. A., Cirolia, G., Fischbach, M. A., & Weissman, J. S. (2021) · eLife · doi:10.7554/elife.65856 · Cited by 31

Comparative Transcriptome Analysis Reveals the Molecular Immunopathogenesis of Chinese Soft-Shelled Turtle (Trionyx sinensis) Infected with Aeromonas hydrophila

Lv, Z., Hu, Y., Tan, J., Wang, X., Liu, X., & Zeng, C. (2021) · Biology · doi:10.3390/biology10111218 · Cited by 31

Mammalian antiviral systems directed by small RNA

Takahashi, T., Heaton, S. M., & Parrish, N. F. (2021) · PLoS Pathogens · doi:10.1371/journal.ppat.1010091 · Cited by 31

Notch1 signaling contributes to TLR4-triggered NF-κB activation in macrophages

Li, L., Jin, J., Liu, H., Ma, X.-F., Wang, D., Song, Y., Wang, C., Jiang, J., Yan, G., Qin, X., et al. (2022) · Pathology - Research and Practice · doi:10.1016/j.prp.2022.153894 · Cited by 32

Pim1 promotes IFN-β production by interacting with IRF3

Ko, R., Seo, J., Park, H., Lee, N., & Lee, S. Y. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-022-00893-y · Cited by 31

TLR4 is one of the receptors for Chikungunya virus envelope protein E2 and regulates virus induced pro-inflammatory responses in host macrophages

Mahish, C., De, S., Chatterjee, S., Ghosh, S., Keshry, S. S., Mukherjee, T., Khamaru, S., Tung, K. S., Subudhi, B. B., Chattopadhyay, S., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1139808 · Cited by 30

Icaritin and intratumoral injection of CpG treatment synergistically promote T cell infiltration and antitumor immune response in mice

Dongye, Z., Wu, X., Wen, Y., Ding, X., Wang, C., Zhao, T., Li, J., & Wu, Y. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109093 · Cited by 31

IL-1β, an important cytokine affecting Helicobacter pylori-mediated gastric carcinogenesis

Yuan, X., Zhang, Y., Zhao, X., Chen, A., & Liu, P. (2022) · Microbial Pathogenesis · doi:10.1016/j.micpath.2022.105933 · Cited by 30

Nitric Oxide Signal Transduction and Its Role in Skin Sensitization

Kim, J. H., & Choi, M. S. (2023) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2023.101 · Cited by 30

In-depth review of delivery carriers associated with vaccine adjuvants: current status and future perspectives

Zeng, Y., Zou, F., Xia, N., & Li, S. (2023) · Expert Review of Vaccines · doi:10.1080/14760584.2023.2238807 · Cited by 31

Mosquito-borne flaviviruses and type I interferon: catch me if you can!

Zoladek, J., & Nisole, S. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1257024 · Cited by 34

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration

He, F., Wu, Z., Liu, C., Zhu, Y., Zhou, Y., Tian, E., Rosin‐Arbesfeld, R., Yang, D., Wang, M., & Zhu, D. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01838-9 · Cited by 31

Lactobacilli-Derived Microbe-Associated Molecular Patterns (MAMPs) in Host Immune Modulation

Furnari, S., Ciantia, R., Garozzo, A., Furneri, P. M., & Fuochi, V. (2025) · Biomolecules · doi:10.3390/biom15111609 · Cited by 37

CITED2 limits pathogenic inflammatory gene programs in myeloid cells

Ng, H. P., Kim, G., Chan, E. R., Dunwoodie, S. L., & Mahabeleshwar, G. H. (2020) · The FASEB Journal · doi:10.1096/fj.202000864r · Cited by 31

Cardiolipin-mediated PPARγ S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia

Garg, M., Johri, S., Sagar, S., Mundhada, A., Agrawal, A., Ray, P., & Chakraborty, K. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108736 · Cited by 28

Kirenol: A Potential Natural Lead Molecule for a New Drug Design, Development, and Therapy for Inflammation

Nasir, N. N., Sekar, M., Fuloria, S., Gan, S. H., Rani, N. N. I. M., Ravi, S., Begum, M. Y., Chidambaram, K., Sathasivam, K. V., Jeyabalan, S., et al. (2022) · Molecules · doi:10.3390/molecules27030734 · Cited by 31

RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13

Zhang, Z., Li, H., Gan, H., Tang, Z., Guo, Y., Yao, S., Liuyu, T., Zhong, B., & Lin, D. (2022) · Advanced Science · doi:10.1002/advs.202105391 · Cited by 30

TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling

Dong, S., Kong, N., Zhang, Y., Li, Y., Sun, D., Qin, W., Zhai, H., Zhai, X., Yang, X., Ye, C., et al. (2022) · Journal of Virology · doi:10.1128/jvi.00070-22 · Cited by 30

Innate immune recognition against SARS-CoV-2

Yamada, T., & Takaoka, A. (2023) · Inflammation and Regeneration · doi:10.1186/s41232-023-00259-5 · Cited by 33

A Self-Immolative DNA Nanogel Vaccine toward Cancer Immunotherapy

Hu, Y., Gao, S., Lu, H., Tan, S., Chen, F., Ke, Y., & Ying, J. Y. (2023) · Nano Letters · doi:10.1021/acs.nanolett.3c02449 · Cited by 30

Stereoselective coronas regulate the fate of chiral gold nanoparticles in vivo

Baimanov, D., Wang, L., Liu, K., Pan, M., Cai, R., Yuan, H., Huang, W., Yuan, Q., Zhou, Y., Chen, C., et al. (2023) · Nanoscale Horizons · doi:10.1039/d3nh00124e · Cited by 33

Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer’s disease

Abdelmaksoud, N. M., Sallam, A.-A. M., Abulsoud, A. I., El‐Dakroury, W. A., Mageed, S. S. A., AL‐Noshokaty, T. M., Elrebehy, M. A., Elshaer, S. S., Mahmoud, N. A., Fathi, D., et al. (2023) · Pathology - Research and Practice · doi:10.1016/j.prp.2023.155007 · Cited by 30

Copper exposure induces inflammation and PANoptosis through the TLR4/NF-κB signaling pathway, leading to testicular damage and impaired spermatogenesis in Wilson disease

Zhao, D., Wu, L., Fang, X., Wang, L., Liu, Q., Jiang, P., Ji, Z., Zhang, N., Yin, M., & Han, H. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.111060 · Cited by 30

Targeted V-type peptide-decorated nanoparticles prevent colitis by inhibiting endosomal TLR signaling and modulating intestinal macrophage polarization

Li, T., Li, Q., Liu, S., Cao, J., Mei, J., Gong, J., Chen, J., Wang, X., Zhang, R., Li, X., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122843 · Cited by 29

The transcription factors GFI1 and GFI1B as modulators of the innate and acquired immune response

Fraszczak, J., & Möröy, T. (2021) · Advances in immunology · doi:10.1016/bs.ai.2021.03.003 · Cited by 28

Cellular nucleic acid–binding protein is essential for type I interferon–mediated immunity to RNA virus infection

Chen, Y., Lei, X., Jiang, Z., & Fitzgerald, K. A. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2100383118 · Cited by 28

Secret messengers: Extracellular RNA communication in the immune system

Nation, G. K., Saffold, C. E., & Pua, H. H. (2021) · Immunological Reviews · doi:10.1111/imr.13027 · Cited by 28

SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response

Singh, S., Garcia, G., Shah, R., Kramerov, A. A., Wright, R. E., Spektor, T. M., Ljubimov, A. V., Arumugaswami, V., & Kumar, A. (2021) · The Ocular Surface · doi:10.1016/j.jtos.2021.09.007 · Cited by 26

Toxic effects of carbon quantum dots on the gut–liver axis and gut microbiota in the common carp Cyprinus carpio

Chen, J., Sun, D., Cui, H., Rao, C., Li, L., Guo, S., Yang, S., Zhang, Y., & Cao, X. (2021) · Environmental Science Nano · doi:10.1039/d1en00651g · Cited by 29

Structure characterization of an arabinogalactan from Cynanchum atratum and its immune stimulatory activity on RAW264.7 cells

Li, N., Yang, F., Su, J., Shi, S., Ordaz-Ortíz, J. J., Cheng, X., Xiong, S., Xu, Y., Wu, J., Wang, H., et al. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.11.172 · Cited by 29

CD11b agonists offer a novel approach for treating lupus nephritis

Villanueva, V., Li, X., Jiménez, V., Faridi, H. M., & Gupta, V. (2022) · Translational research · doi:10.1016/j.trsl.2022.03.001 · Cited by 29

Advances in the therapeutic application and pharmacological properties of kinsenoside against inflammation and oxidative stress-induced disorders

Lü, L., Xiong, Y., Lin, Z., Chu, X., Panayi, A. C., Hu, Y., Zhou, J., Mi, B., & Liu, G. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1009550 · Cited by 29

Comprehensive analysis of expression profile and prognostic significance of interferon regulatory factors in pancreatic cancer

Zhang, K., Xu, P., Li, Y., Dong, S., Gao, H., Chen, L., Chen, H., & Chen, Z. (2022) · BMC Genomic Data · doi:10.1186/s12863-021-01019-5 · Cited by 28

Nuclear RPSA senses viral nucleic acids to promote the innate inflammatory response

Jiang, Y., Sun, S., Quan, Y., Wang, X., You, Y., Zhang, X., Zhang, Y., Liu, Y., Wang, B., Xu, H., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-43784-0 · Cited by 30

Crucial Roles of RSAD2/viperin in Immunomodulation, Mitochondrial Metabolism and Autoimmune Diseases

Chen, S., Ye, J., Lin, Y., Chen, W., Huang, S., Yang, Q., Qian, H., Gao, S., & Hua, C. (2024) · Inflammation · doi:10.1007/s10753-024-02076-5 · Cited by 28

Tissue geometry spatiotemporally drives bacterial infections.

Han, Y.-M., Liu, X., Qu, S., Duan, X.-C., Xiang, Y.-Q., Jiang, N., Yang, S.-Y., Fang, X., Xu, L., Wen, H., et al. (2025) · Cell · doi:10.1016/j.cell.2025.03.042 · Cited by 33

The gut microbiota and cardiovascular disease: Exploring the role of microbial dysbiosis and metabolites in pathogenesis and therapeutics

Mohsenzadeh, A., Pourasgar, S., Mohammadi, A., Nazari, M., Nematollahi, S., Karimi, Y., Firoozbakhsh, P., Mohsenzadeh, H., Kamali, K., & Elahi, R. (2025) · Life Sciences · doi:10.1016/j.lfs.2025.123981 · Cited by 33

New Decade, Old Debate: Blocking the Cytokine Pathways in Infection-Induced Cytokine Cascade

Rizvi, M. S., & de Moraes, A. G. (2021) · Critical Care Explorations · doi:10.1097/cce.0000000000000364 · Cited by 27

Coronavirus infection: An immunologists' perspective

Sanctis, J. B. D., García, A. H., Moreno, D., & Hajdúch, M. (2021) · Scandinavian Journal of Immunology · doi:10.1111/sji.13043 · Cited by 27

Harnessing Metabolic Reprogramming to Improve Cancer Immunotherapy

Liang, Y., Tan, Y., Chen, G., Fan, J., & Zhang, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910268 · Cited by 29

Novel Vaccine Adjuvants as Key Tools for Improving Pandemic Preparedness

Pogostin, B. H., & McHugh, K. J. (2021) · Bioengineering · doi:10.3390/bioengineering8110155 · Cited by 28

IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function

Li, S., Yao, J.-C., Oetjen, K. A., Krambs, J. R., Xia, J., Zhang, J., Schmidt, A. P., Helton, N., Fulton, R. S., Heath, S. E., et al. (2022) · Blood · doi:10.1182/blood.2022016084 · Cited by 29

LPS stimulation stabilizes HIF ‐1α by enhancing HIF ‐1α acetylation via the PARP1‐SIRT1 and ACLY‐Tip60 pathways in macrophages

Chen, Q., Cui, K., Zhao, Z., Xu, X., Liu, Y., Shen, Y., Chen, F., Mai, K., & Ai, Q. (2022) · The FASEB Journal · doi:10.1096/fj.202200256r · Cited by 28

A Review on Immunological Responses to SARS-CoV-2 and Various COVID-19 Vaccine Regimens

Upreti, S., & Samant, M. (2022) · Pharmaceutical Research · doi:10.1007/s11095-022-03323-w · Cited by 29

Human repair‐related Schwann cells adopt functions of antigen‐presenting cells in vitro

Berner, J., Weiss, T., Sorger, H., Rifatbegovic, F., Kauer, M., Windhager, R. H., Dohnal, A. M., Ambros, P. F., Ambros, I. M., Boztuǧ, K., et al. (2022) · Glia · doi:10.1002/glia.24257 · Cited by 27

Dietary mannan oligosaccharides strengthens intestinal immune barrier function via multipath cooperation during Aeromonas Hydrophila infection in grass carp (Ctenopharyngodon Idella)

Lu, Z., Feng, L., Jiang, W., Wu, P., Liu, Y., Jiang, J., Kuang, S., Tang, L., Li, S., Zhong, C.-B., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1010221 · Cited by 28

Rapid glycolytic activation accompanying innate immune responses: mechanisms and function

Namgaladze, D., & Brüne, B. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1180488 · Cited by 31

Resolution of inflammation: Intervention strategies and future applications

Panezai, J., & Dyke, T. E. V. (2022) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2022.116089 · Cited by 30

Modulation of adipose tissue metabolism by microbial-derived metabolites

Liu, W., Ge, Y., Liu, P., Jiang, X. M., & Xin, Y. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.1031498 · Cited by 30

USP39 Regulates NF-κB–Mediated Inflammatory Responses through Deubiquitinating K48-Linked IκBα

Quan, J., Zhao, X., Xiao, Y., Wu, H., Di, Q., Wu, Z., Chen, X., Tang, H., Zhao, J., Guan, Y., et al. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2200603 · Cited by 27

Circadian Regulation of Macrophages and Osteoclasts in Rheumatoid Arthritis

Kikyo, N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512307 · Cited by 27

Radioresponsive Delivery of Toll-like Receptor 7/8 Agonist for Tumor Radioimmunotherapy Enabled by Core-Cross-Linked Diselenide Nanoparticles

Wu, Y., Qin, J., Gu, Y., Zhao, G., Xu, P., Lin, S., Cheng, X., Zhang, L. W., Wang, Y., & Wang, Y. (2024) · ACS Nano · doi:10.1021/acsnano.3c05882 · Cited by 27

Brucella infection and Toll-like receptors

Yu, H. L., Gu, X., Wang, D., & Wang, Z. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1342684 · Cited by 27

Exploration of gut microbiome and inflammation: A review on key signalling pathways

Nigam, M., Devi, K., Coutinho, H. D. M., & Mishra, A. P. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111140 · Cited by 31

Combined toxic effects of polyethylene microplastics and lambda-cyhalothrin on gut of zebrafish (Danio rerio)

Zhao, Y., Chen, H., Liang, H., Zhao, T., Ren, B. X., Li, Y., Liang, H., Liu, Y., Cao, H., Cui, N., et al. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116296 · Cited by 27

Threonine phosphorylation of STAT1 restricts interferon signaling and promotes innate inflammatory responses

Metwally, H., Elbrashy, M. M., Ozawa, T., Okuyama, K., White, J. T., Tulyeu, J., Søndergaard, J. N., Wing, J. B., Muratsu, A., Matsumoto, H., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2402226121 · Cited by 27

Structural characterization of macro domain–containing Thoeris antiphage defense systems

Shi, Y. Y., Masic, V., Mosaiab, T., Rajaratman, P., Hartley‐Tassell, L. E., Sorbello, M., Goulart, C. C., Vasquez, E., Mishra, B. P., Holt, S., et al. (2024) · Science Advances · doi:10.1126/sciadv.adn3310 · Cited by 29

The role of TIR domain-containing proteins in bacterial defense against phages

Wang, S., Kuang, S., Song, H., Sun, E., Li, M., Liu, Y., Xia, Z., Zhang, X., Wang, X., Han, J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-51738-3 · Cited by 27

A bacterial immunity protein directly senses two disparate phage proteins

Zhang, T., Čepauskas, A., Nadieina, A., Thureau, A., Wallant, K. C. ’., Martens, C., Lim, D., García-Pino, A., & Laub, M. T. (2024) · Nature · doi:10.1038/s41586-024-08039-y · Cited by 29

Promotion of TLR7-MyD88-dependent inflammation and autoimmunity in mice through stem-loop changes in Lnc-Atg16l1

Yang, Z., Ji, S., Liu, L., Liu, S., Wang, B., Ma, Y., & Cao, X. (2024) · Nature Communications · doi:10.1038/s41467-024-54674-4 · Cited by 27

How the early life microbiome shapes immune programming in childhood asthma and allergies

Hoskinson, C., Petersen, C., & Turvey, S. E. (2024) · Mucosal Immunology · doi:10.1016/j.mucimm.2024.12.005 · Cited by 28

Focusing on the interplay between tumor-associated macrophages and tumor microenvironment: from mechanism to intervention

Wu, H., Li, J., Yao, R., Liu, J., Su, L., & You, W. (2025) · Theranostics · doi:10.7150/thno.113727 · Cited by 30

The roles of S100A8/A9 and S100A12 in autoimmune diseases: Mechanisms, biomarkers, and therapeutic potential

Wang, X., Luo, Y., Zhou, Q., & Ma, J. (2025) · Autoimmunity Reviews · doi:10.1016/j.autrev.2025.103920 · Cited by 27

Effects of different temperatures and protein levels on growth performance, physiological response and expression of immune-related genes of juvenile oriental river prawn (Macrobrachium nipponense)

Lv, B., Liu, B., Zhou, Q.-L., Song, C.-Y., Sun, C.-X., Zhang, H.-M., Jiang, Z.-T., Jiang, S.-F., & Liu, M. (2021) · Aquaculture · doi:10.1016/j.aquaculture.2021.736435 · Cited by 27

Cubic multi-ions-doped Na2TiO3 nanorod-like coatings: Structure-stable, highly efficient platform for ions-exchanged release to immunomodulatory promotion on vascularized bone apposition

Yu, D., Li, B., Yu, M., Guo, S., Guo, Z., & Han, Y. N. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.01.039 · Cited by 27

TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

Iberg, C. A., Bourque, J., Fallahee, I., Son, S., & Hawiger, D. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110657 · Cited by 27

Gut microbiota alteration and modulation in hepatitis B virus-related fibrosis and complications: Molecular mechanisms and therapeutic inventions

Li, Y., Yu, Z., Li, A., & Ren, Z. (2022) · World Journal of Gastroenterology · doi:10.3748/wjg.v28.i28.3555 · Cited by 28

Neuroinflammatory Gene Expression Analysis Reveals Pathways of Interest as Potential Targets to Improve the Recording Performance of Intracortical Microelectrodes

Song, S., Regan, B., Ereifej, E. S., Chan, E. R., & Capadona, J. R. (2022) · Cells · doi:10.3390/cells11152348 · Cited by 28

Infection-induced membrane ruffling initiates danger and immune signaling via the mechanosensor PIEZO1

Tadala, L., Langenbach, D., Dannborg, M., Cervantes-Rivera, R., Sharma, A., Vieth, K., Rieckmann, L. M., Wanders, A., Cisneros, D. A., & Puhar, A. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111173 · Cited by 28

TLR2 agonist promotes myeloid-derived suppressor cell polarization via Runx1 in hepatocellular carcinoma

Li, S., Li, F., Xu, L., Liu, X., Zhu, X., Gao, W., & Shen, X. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109168 · Cited by 27

New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants

Romerio, A., Gotri, N., Franco, A. R., Artusa, V., Shaik, M. M., Pasco, S. T., Atxabal, U., Matamoros‐Recio, A., Mínguez-Toral, M., Zalamea, J. D., et al. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c01998 · Cited by 29

Shenfu injection: a review of pharmacological effects on cardiovascular diseases

Xu, F., Xie, X., Hu, H., Tong, R., & Peng, C. Y. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1279584 · Cited by 26

The pharmacoepigenetic paradigm in cancer treatment

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