Toll-like Receptors and the Control of Immunity

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Shi, J., Zhao, Y., Wang, K., Shi, X., Wang, Y., Huang, H., Zhuang, Y., Cai, T., Wang, F., & Shao, F. (2015) · Nature · doi:10.1038/nature15514 · Cited by 6,659

Origin and physiological roles of inflammation

Medzhitov, R. (2008) · Nature · doi:10.1038/nature07201 · Cited by 6,618

A Toll-like receptor recognizes bacterial DNA

Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) · Nature · doi:10.1038/35047123 · Cited by 6,491

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Medzhitov, R., Preston-Hurlburt, P., & Janeway, C. A. J. (1997) · Nature · doi:10.1038/41131 · Cited by 6,137

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature · doi:10.1038/35099560 · Cited by 6,129

The Inflammasome

Martinon, F., Burns, K., & Tschopp, J. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00599-3 · Cited by 6,066

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Sun, L., Wu, J., Du, F., Chen, X., & Chen, Z. J. (2013) · Science · doi:10.1126/science.1232458 · Cited by 4,996

Mutations affecting segment number and polarity in Drosophila

Nüsslein‐Volhard, C., & Wieschaus, E. F. (1980) · Nature · doi:10.1038/287795a0 · Cited by 4,370

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Lemaître, B., Nicolas, E., Michaut, L., Reichhart, J., & Hoffmann, J. A. (1996) · Cell · doi:10.1016/s0092-8674(00)80172-5 · Cited by 4,224

The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells

Descamps, D., Evnouchidou, I., Caillens, V., Drajac, C., Riffault, S., Endert, P. V., & Saveanu, L. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.583556 · Cited by 28

Toll-like receptor 5-mediated signaling enhances liver regeneration in mice

Zhang, W., Wang, L., Sun, X., Liu, X., Xiao, Y., Zhang, J., Wang, T., Chen, H., Zhan, Y., Yu, M., et al. (2021) · Military Medical Research · doi:10.1186/s40779-021-00309-4 · Cited by 27

Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level

Clark, H. R., McKenney, C. D., Livingston, N. M., Gershman, A., Sajjan, S., Chan, I. S., Ewald, A. J., Timp, W., Wu, B., Singh, A., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22070-x · Cited by 26

TLR4 is required for macrophage efferocytosis during resolution of ventilator-induced lung injury

Su, K., Bo, L., Jiang, C., Deng, X., Zhao, Y., Minshall, R. D., & Hu, G. (2021) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00226.2021 · Cited by 24

Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice

Pi, A., Jiang, K., Ding, Q., Lai, S., Yang, W., Zhu, J., Guo, R., Fan, Y., Chi, L., & Li, S. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.752148 · Cited by 25

Preventive Effect of a Postbiotic and Prebiotic Mixture in a Rat Model of Early Life Rotavirus Induced-Diarrhea

Morales-Ferré, C., Azagra-Boronat, I., Massot‐Cladera, M., Tims, S., Knipping, K., Garssen, J., Knol, J., Franch, À., Castell, M., Pérez-Cano, F. J., et al. (2022) · Nutrients · doi:10.3390/nu14061163 · Cited by 27

Emerging role of RNA sensors in tumor microenvironment and immunotherapy

Yang, R. Y., Yu, S., Xu, T., Zhang, J., & Wu, S. (2022) · Journal of Hematology & Oncology · doi:10.1186/s13045-022-01261-z · Cited by 27

Cross-Talk between the Cytokine IL-37 and Thyroid Hormones in Modulating Chronic Inflammation Associated with Target Organ Damage in Age-Related Metabolic and Vascular Conditions

Majnarić, L. T., Bosnić, Z., Štefanić, M., & Wittlinger, T. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126456 · Cited by 27

Innate and Adaptive Responses of Intratumoral Immunotherapy with Endosomal Toll-Like Receptor Agonists

Torres, F., Leon, S., Ummarino, A., Redín, E., Allavena, P., Serrano, D., Anfray, C., & Calvo, A. (2022) · Biomedicines · doi:10.3390/biomedicines10071590 · Cited by 24

Sustained Inflammation Induced by LPS Leads to Tolerable Anorexia and Fat Loss via Tlr4 in Mice

Yang, Y., Zhong, W., Zhang, Y., Cheng, Y., Lai, H., Yu, H., Feng, N., Han, Y., Huang, R., & Zhai, Q. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s358518 · Cited by 27

L-Theanine Modulates Intestine-Specific Immunity by Regulating the Differentiation of CD4+ T Cells in Ovalbumin-Sensitized Mice

Qu, Q.-Y., Song, X.-Y., Lin, L., Gong, Z., Xu, W., & Xiao, W. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c06171 · Cited by 25

Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages

Wang, Y., Wang, Y., Ding, L., Ren, X., Wang, B., Wang, L., Zhao, S., Yue, X., Wu, Z., Li, C., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111738 · Cited by 27

HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages

Gupta, K. D., Ramnath, D., von Pein, J. B., Curson, J. E. B., Wang, Y., Abrol, R., Kakkanat, A., Moradi, S. V., Gunther, K. S., Murthy, A. M. V., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2212813120 · Cited by 25

E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2

Zhang, J., Cao, L., Gao, A., Ren, R., Yu, L., Li, Q., Liu, Y., Qi, W., Hou, Y., Sui, W., et al. (2023) · Cell Death and Differentiation · doi:10.1038/s41418-023-01115-2 · Cited by 25

Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen

Chen, P., Zhou, Y., Li, X., Yang, J., Zheng, Z., Zou, Y., Li, X., Liao, J. P., Dai, J., Xu, Y., et al. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c00359 · Cited by 25

The role of toll‐like receptors in immune tolerance induced by Helicobacter pylori infection

Zhang, X., Zhang, K., Yan, L., Wang, P., Zhao, F., & Hu, S. (2023) · Helicobacter · doi:10.1111/hel.13020 · Cited by 25

Integrated bioinformatics and network pharmacology to explore the therapeutic target and molecular mechanisms of Bailing capsule on polycystic ovary syndrome

Guan, H.-R., Li, B., Zhang, Z.-H., Wu, H.-S., He, X., Dong, Y., Su, J., Lv, G., & Chen, S. (2023) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-023-04280-6 · Cited by 27

miR-708–5p deficiency involves the degeneration of mandibular condylar chondrocytes via the TLR4/NF-κB pathway

Xu, L., Zhang, Y., Yu, J., Huo, W., Xu, J., Yang, H., Zhang, M., Yu, S., Wu, Y., & Wang, M. (2024) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2024.02.007 · Cited by 25

Mesenchymal stem cell-derived exosomes ameliorate diabetic kidney disease through NOD2 signaling pathway

Wang, Y., Lu, D., Lv, S., Liu, X., & Liu, G. (2024) · Renal Failure · doi:10.1080/0886022x.2024.2381597 · Cited by 26

Mechanisms of Keap1/Nrf2 modulation in bacterial infections: implications in persistence and clearance

Romero-Durán, M. A., Silva-García, O., Perez‐Aguilar, J. M., & Baizabal-Aguirre, V. M. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1508787 · Cited by 26

Gut microbiome-derived lipopolysaccharides aggravate cognitive impairment via TLR4-mediated inflammatory signaling in neonatal rats following hypoxic-ischemic brain damage

Wei, J., Chen, A., Huang, D., Teng, C., Cai, D., Wu, X., Wang, T., Hu, W., Huang, Z., Wang, P., et al. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.02.029 · Cited by 24

Astragalus polysaccharides: structure-immunomodulation relationships, multi-target pharmacological activities, and cutting-edge applications in immune modulation

Wang, B., Wu, B., Ma, Y., Liu, X., Tao, L., Jia, L., Ding, X., & Zhou, X. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1714898 · Cited by 27

The immune system of sturgeons and paddlefish (Acipenseriformes): a review with new data from a chromosome‐scale sturgeon genome

Höhne, C., Prokopov, D., Kuhl, H., Du, K., Klopp, C., Wuertz, S., Trifonov, V. A., & Stöck, M. (2021) · Reviews in Aquaculture · doi:10.1111/raq.12542 · Cited by 24

ACE2 and Innate Immunity in the Regulation of SARS-CoV-2-Induced Acute Lung Injury: A Review

Qu, L., Chen, C., Yin, T., Fang, Q., Hong, Z.-Z., Zhou, R., Tang, H., & Dong, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111483 · Cited by 23

Fish-specific TLR18 in Nile tilapia (Oreochromis niloticus) recruits MyD88 and TRIF to induce expression of effectors in NF-κB and IFN pathways in melanomacrophages

Trung, N. B., Nan, F., Lee, M., Loh, J., Gong, H., Lu, M., Hang, H. T., Lin, Y., & Lee, P. (2021) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2021.11.001 · Cited by 24

Structural characterization and protective effects of polysaccharide from Gracilaria lemaneiformis on LPS-induced injury in IEC-6 cells

Li, X., Gong, Y., Yao, W., Chen, X., Xian, J., You, L., & Fardim, P. (2021) · Food Chemistry X · doi:10.1016/j.fochx.2021.100157 · Cited by 24

The Role of Long Noncoding RNA BST2-2 in the Innate Immune Response to Viral Infection

Chen, S., Huang, X., Xie, Q., Liu, Q., & Zhu, H. (2022) · Journal of Virology · doi:10.1128/jvi.00207-22 · Cited by 23

Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia

Wang, X. B., Lin, C., Wu, S., Zhang, T., Wang, Y., Jiang, Y., & Wang, X. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.929222 · Cited by 24

RIG-I–like Receptor Regulation of Immune Cell Function and Therapeutic Implications

Solstad, A., Hogaboam, O., Forero, A., & Hemann, E. A. (2022) · The Journal of Immunology · doi:10.4049/jimmunol.2200395 · Cited by 25

Gastric protective effect of Alpinia officinarum flavonoids: mediating TLR4/NF-κB and TRPV1 signalling pathways and gastric mucosal healing

Lin, K., Deng, T., Qu, H., Ou, H., Huang, Q., Gao, B., Li, X., & Wei, N. (2022) · Pharmaceutical Biology · doi:10.1080/13880209.2022.2152058 · Cited by 24

Roles of human trophoblasts’ pattern recognition receptors in host defense and pregnancy complications

Motomura, K., Hara, M., Ito, I., Morita, H., & Matsumoto, K. (2023) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2023.103811 · Cited by 26

Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway

Zhao, L., Miao, Y., Shan, B., Zhao, C., Peng, C., & Gong, J. (2023) · Foods · doi:10.3390/foods12071468 · Cited by 24

A “bulldozer” driven by anoxic bacteria for pancreatic cancer chemo-immunotherapy

Zhang, H., Wang, Y., Zhu, L., Qi, Z., Cao, K., Chang, J., & Hou, L. (2023) · Journal of Controlled Release · doi:10.1016/j.jconrel.2023.07.014 · Cited by 25

Lipid-hybrid cell-derived biomimetic functional materials: A state-of-the-art multifunctional weapon against tumors

Liu, W.-S., Wu, L., Chen, C.-M., Zheng, H., Gao, J., Lu, Z., & Li, M. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100751 · Cited by 24

Lipopolysaccharide-Induced TRPA1 Upregulation in Trigeminal Neurons is Dependent on TLR4 and Vesicular Exocytosis

Michot, B., Casey, S. M., Lee, C. S., Erdoğan, Ö., Basu, H., Chiu, I. M., & Gibbs, J. L. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0162-23.2023 · Cited by 23

TLR7 neo-functionalizes to sense dsRNA and trigger antiviral and antibacterial immunity in non-tetrapod vertebrates

Jiang, R., Zhu, W., Liao, Z., Yang, C., & Su, J. (2023) · iScience · doi:10.1016/j.isci.2023.108315 · Cited by 23

SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms

Sugisawa, R., Shanahan, K. A., Davis, G. M., Davey, G. P., & Bowie, A. (2024) · iScience · doi:10.1016/j.isci.2024.109940 · Cited by 23

Innate immunity-mediated neuroinflammation promotes the onset and progression of post-stroke depression

Xiao, M., Chen, Y., & Mu, J. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.114937 · Cited by 23

Decoding osteoporosis: Understanding the disease, exploring current and new therapies and emerging targets

Patel, D., & Saxena, B. (2024) · Journal of Orthopaedic Reports · doi:10.1016/j.jorep.2024.100472 · Cited by 29

Rethinking Toll-like receptor signalling

Bryant, C. E. (2024) · Current Opinion in Immunology · doi:10.1016/j.coi.2024.102460 · Cited by 23

Nanostructured lipid carriers based mRNA vaccine leads to a T cell–inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumour model

Fournier, C., Mercey-Ressejac, M., Dérangère, V., Kadi, A. A., Rageot, D., Charrat, C., Leroy, A., Vollaire, J., Josserand, V., Escudé, M., et al. (2025) · EBioMedicine · doi:10.1016/j.ebiom.2024.105543 · Cited by 27

Interferon-stimulated gene IFI27 as a multifaceted candidate target in precision medicine

Shojaei, M., & McLean, A. S. (2025) · Trends in Immunology · doi:10.1016/j.it.2025.01.008 · Cited by 23

Chlorogenic acid mitigates avian pathogenic Escherichia coli-induced intestinal barrier damage in broiler chickens via anti-inflammatory and antioxidant effects

Wei, L., Liu, X., Tan, Z., Zhang, B., Wen, C., Tang, Z., Zhou, Y., Zhang, H., & Chen, Y. (2025) · Poultry Science · doi:10.1016/j.psj.2025.105005 · Cited by 23

Toll-like Receptor (TLR)-induced Rasgef1b expression in macrophages is regulated by NF-κB through its proximal promoter

Leão, F. B., Vaughn, L. S., Bhatt, D. M., Liao, W., Maloney, D., Carvalho, B. C., de Oliveira, L. C., Ghosh, S., & Silva, A. M. (2020) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2020.105840 · Cited by 24

Molecular insights into the biochemical functions and signalling mechanisms of plant NLRs

Liu, X., & Wan, L. (2022) · Molecular Plant Pathology · doi:10.1111/mpp.13195 · Cited by 23

MicroRNAs in the cancer cell-to-cell communication: An insight into biological vehicles

Mansoori, B., Baradaran, B., Nazari, A., Gaballu, F. A., Cho, W. C. S., & Mansoori, B. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113449 · Cited by 24

Protective role of TLR 9‐induced macrophage/microglia phagocytosis after experimental intracerebral hemorrhage in mice

Wei, J., Dai, S., Pu, C., Luo, P., Yang, Y., Jiang, X., Li, X., Lin, W. J., & Fei, Z. (2022) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.13919 · Cited by 22

Schizophrenia and obesity: May the gut microbiota serve as a link for the pathogenesis?

Wu, H., Liu, Y., Wang, J., Chen, S., Xie, L., & Wu, X. (2023) · iMeta · doi:10.1002/imt2.99 · Cited by 24

Human leptospirosis: In search for a better vaccine

Azevedo, I. R., Amamura, T. A., & Isaac, L. (2023) · Scandinavian Journal of Immunology · doi:10.1111/sji.13316 · Cited by 27

Loss of function of ENT3 drives histiocytosis and inflammation through TLR-MAPK signaling

Shiloh, R., Lubin, R., David, O., Geron, I., Okon, E., Hazan, I., Zaliova, M. K., Amarilyo, G., Birger, Y., Borovitz, Y., et al. (2023) · Blood · doi:10.1182/blood.2023020714 · Cited by 23

Symbiotic microbial communities in various locations of the lung cancer respiratory tract along with potential host immunological processes affected

Cheng, J., Zhou, L., & Wang, H. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1296295 · Cited by 24

Interaction between the SFTSV envelope glycoprotein Gn and STING inhibits the formation of the STING-TBK1 complex and suppresses the NF-κB signaling pathway

Jia, Y., Li, F., Liu, Z. L., Liu, S., Huang, M., Gao, X., Su, X., Wang, Z., & Wang, T. (2024) · Journal of Virology · doi:10.1128/jvi.01815-23 · Cited by 24

Dysregulation of genes and microRNAs in Localized Aggressive Periodontitis.

Fernandes, J. G., Morford, L., Harrison, P., Kompotiati, T., Huang, H., Aukhil, I., Wallet, S. M., & Shaddox, L. (2020) · Journal of Clinical Periodontology · doi:10.1111/jcpe.13361 · Cited by 22

Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways

Manes, N. P., & Nita‐Lazar, A. (2021) · mSystems · doi:10.1128/msystems.00336-21 · Cited by 23

Underwhelming or Misunderstood? Genetic Variability of Pattern Recognition Receptors in Immune Responses and Resistance to Mycobacterium tuberculosis

Dubé, J.-Y., Fava, V. M., Schurr, E., & Behr, M. A. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.714808 · Cited by 23

Maternal supplementation with Artemisia annua L. ameliorates intestinal inflammation via inhibiting the TLR4/NF-κB and MAPK pathways and improves the oxidative stability of offspring

Zhang, S., Xiong, L., Cui, C., Zhao, H., Zhang, Y., Tian, Z., Guan, W., & Chen, F. (2022) · Food & Function · doi:10.1039/d2fo00675h · Cited by 22

The role of toll-like receptors in orchestrating osteogenic differentiation of mesenchymal stromal cells and osteoimmunology

Liu, X., Zhou, Z., Zeng, W., Zeng, Q., & Zhang, X. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1277686 · Cited by 25

The Role of the Innate Immune Response in Oral Mucositis Pathogenesis

Bowen, J. M., & Cross, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216314 · Cited by 23

Immune Evasion of Mycoplasma gallisepticum: An Overview

Liu, Y., Wang, Y., & Zheng, S. J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25052824 · Cited by 22

Microglial polarization in Alzheimer's disease: Mechanisms, implications, and therapeutic opportunities

Yang, X., Wang, J., Jia, X.-T., Yang, Y., Fang, Y., Ying, X., Li, H., Zhang, M., Wei, J., & Pan, Y. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877241313223 · Cited by 22

Recent Progress in Radiosensitive Nanomaterials for Radiotherapy-Triggered Drug Release

Jiang, R., Fang, Q., Liu, W., Chen, L., & Yang, H. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c23023 · Cited by 22

Rational computational design and development of an immunogenic multiepitope vaccine incorporating transmembrane proteins of Fusobacterium necrophorum

Naveed, M., Toheed, M., Aziz, T., Asim, M., Qadir, P., Rehman, H. M., Mohamed, R. A. E. H., Al‐Joufi, F. A., Alwethaynani, M. S., & Fallatah, D. I. (2025) · Scientific Reports · doi:10.1038/s41598-025-00166-4 · Cited by 22

Interferon and immunity: the role of microRNA in viral evasion strategies

Bayat, M., Samiei, R. N., Nahand, J. S., & Naghili, B. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1567459 · Cited by 27

Loss-of-function mutations in PLD4 lead to systemic lupus erythematosus

Wang, Q., Zhu, H., Sun, X., Zhang, C., Ma, S., Jin, Y., Fu, J., Liu, C., Peng, J., Wang, R., et al. (2025) · Nature · doi:10.1038/s41586-025-09513-x · Cited by 22

The gut microbiota and host immunity synergistically orchestrate colonization resistance

Li, N., & Guo, X. (2026) · Gut Microbes · doi:10.1080/19490976.2025.2611545 · Cited by 26

Self-Nucleic Acid Sensing: A Novel Crucial Pathway Involved in Obesity-Mediated Metaflammation and Metabolic Syndrome

Ferrière, A., Santa, P., Garreau, A., Bandopadhyay, P., Blanco, P., Ganguly, D., & Sisirak, V. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.624256 · Cited by 24

For whom the disc tolls: intervertebral disc degeneration, back pain and toll-like receptors

Bisson, D. G., Mannarino, M., Racine, R., & Haglund, L. (2021) · European Cells and Materials · doi:10.22203/ecm.v041a23 · Cited by 22

Activation of Toll-Like Receptor 7 Signaling Pathway in Primary Sjögren's Syndrome-Associated Thrombocytopenia

Zhang, S., Qu, J., Wang, L., Li, M., Xu, D., Zhao, Y., Zhang, F., & Zeng, X. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.637659 · Cited by 22

Cytosolic detection of phagosomal bacteria—Mechanisms underlying PAMP exodus from the phagosome into the cytosol

Ragland, S. A., & Kagan, J. C. (2021) · Molecular Microbiology · doi:10.1111/mmi.14841 · Cited by 22

Herpes simplex virus interference with immunity: Focus on dendritic cells

Farías, M. A., Duarte, L. F., Tognarelli, E. I., & González, P. A. (2021) · Virulence · doi:10.1080/21505594.2021.1980990 · Cited by 23

SARS-CoV-2-mediated evasion strategies for antiviral interferon pathways

Oh, S. J., & Shin, O. S. (2022) · The Journal of Microbiology · doi:10.1007/s12275-022-1525-1 · Cited by 23

Transcriptome Analysis Indicates Immune Responses against Vibrio harveyi in Chinese Tongue Sole (Cynoglossus semilaevis)

Zhang, X., Hao, X., Ma, W., Zhu, T., Zhang, Z., Wang, Q., Liu, K., Shao, C., & Wang, H. (2022) · Animals · doi:10.3390/ani12091144 · Cited by 22

CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity

Long, Y., Sun, J., Song, T., Liu, T., Tang, F., Zhang, X., Ding, L., Miao, Y., Zhu, W., Pan, X., et al. (2022) · Cell Discovery · doi:10.1038/s41421-021-00370-2 · Cited by 22

P2Y6 receptor-mediated signaling amplifies TLR-induced pro-inflammatory responses in microglia

Timmerman, R., Zuiderwijk-Sick, E. A., & Bajramovic, J. J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.967951 · Cited by 22

Immune mechanisms in fibrotic pulmonary sarcoidosis

Weeratunga, P. N., Möller, D. R., & Ho, L. (2022) · European Respiratory Review · doi:10.1183/16000617.0178-2022 · Cited by 22

The Anti-Inflammatory Mechanism of Flaxseed Linusorbs on Lipopolysaccharide-Induced RAW 264.7 Macrophages by Modulating TLR4/NF-κB/MAPK Pathway

Li, J., Chen, J., Huang, P. H., Cai, Z., Zhang, N., Wang, Y., & Li, Y. (2023) · Foods · doi:10.3390/foods12122398 · Cited by 22

Targeting Inflammasome Activation in Viral Infection: A Therapeutic Solution?

Deng, C.-H., Li, T., Zhang, W., Zhao, Q., & Wang, Y. (2023) · Viruses · doi:10.3390/v15071451 · Cited by 23

Single-cell transcriptome, phagocytic activity and immunohistochemical analysis of crucian carp (Carassius auratus) in response to Rahnella aquatilis infection

Huo, Y., Hu, X., Lü, J., Luo, F., Liang, J., Lei, H., & Lv, A. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.108970 · Cited by 22

The antimicrobial peptide chensinin-1b alleviates the inflammatory response by targeting the TLR4/NF-κB signaling pathway and inhibits Pseudomonas aeruginosa infection and LPS-mediated sepsis

Li, Z., Qu, W., Zhang, D., Sun, Y., & Shang, D. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115227 · Cited by 23

Schaftoside reduces inflammation in Aspergillus fumigatus keratitis through the inhibition of the TLR4/MyD88 pathway

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