Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet
Open accessAbstract
The most extreme environments are the most vulnerable to transformation under a rapidly changing climate. These ecosystems harbor some of the most specialized species, which will likely suffer the highest extinction rates. We document the steepest temperature increase (2010-2021) on record at altitudes of above 4,000 m, triggering a decline of the relictual and highly adapted moss Takakia lepidozioides. Its de-novo-sequenced genome with 27,467 protein-coding genes includes distinct adaptations to abiotic stresses and comprises the largest number of fast-evolving genes under positive selection. The uplift of the study site in the last 65 million years has resulted in life-threatening UV-B radiation and drastically reduced temperatures, and we detected several of the molecular adaptations of Takakia to these environmental changes. Surprisingly, specific morphological features likely occurred earlier than 165 mya in much warmer environments. Following nearly 400 million years of evolution and resilience, this species is now facing extinction.
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Whilst plants and animals in alpine regions are well adapted to both high UV-B radiation and cold environments, there is some evidence that such adaptation may reduce their capacity to adapt to warming environments.
“Whilst plants and animals in alpine regions are well adapted to both high UV-B radiation and cold environments [197, 198], there is some evidence that such adaptation may reduce their capacity to adapt to warming environments [199].”
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Self-citationThe evolutionary emergence of land plants.
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Accurate timetrees require accurate calibrations
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Bryophytes hold a larger gene family space than vascular plants
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Self-citationNew national and regional bryophyte records, 78
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A snapshot of the Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins
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Self-citationDifferential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases
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Self-citationExploring fern pathosystems and immune receptors to bridge gaps in plant immunity
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“…of land plants, including bryophytes ( Marchantia paleacea [46], Marchantia polymorpha [47], Physcomitrium patens [48], Takakia lepidozioides [49]); lycophytes ( Diphasiastrum complanatum [50], Isoetes sinensis [51], Selaginella moellendorffii [52]), ferns ( Alsophila spinulosa [9],…”
Multiplication of peat moss ( Sphagnum L.) species for climate action
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Self-citationCRISPR/Cas9 targeted genetic screening in Physcomitrella identifies novel cell division genes
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Himalayan moss Takakia: a tale of its evolution, adaptation, and climate crisis
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Functional characterisation of Target of Rapamycin (TOR) signalling in Physcomitrella
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Grappling with algal biodiversity
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Decoding genetic diversity through genome engineering in bryophytes
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Self-citationCNGCs in Marchantia paleacea uncouple arbuscular mycorrhizal symbiosis and rhizoid development
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This moss survived 165 million years — and now it's under threat from climate change
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Short Communication: Ardeuma filiforme (Pottiaceae) disjunctive from Peru to India
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Population genomics: A new chapter for Marchantia biology
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- Authors
- Hu, R., Li, X., Hu, Y., Zhang, R., Lv, Q., Zhang, M., Sheng, X., Zhao, F., Chen, Z., Ding, Y., Yuan, H., Wu, X., Xing, S., Yan, X., Bao, F., Wan, P., Xiao, L., Wang, X., Xiao, W., Decker, E. L., van Gessel, N., Renault, H., Wiedemann, G., Horst, N. A., Haas, F. B., Wilhelmsson, P. K. I., Ullrich, K. K., Neumann, E., Lv, B., Liang, C., Du, H., Lu, H., Gao, Q., Cheng, Z., You, H., Xin, P., Chu, J., Huang, C.-H., Liu, Y., Dong, S., Zhang, L., Chen, F., Deng, L., Duan, F., Zhao, W., Li, K., Li, Z., Li, X., Cui, H., Zhang, Y. E., Ma, C., Zhu, R., Jia, Y., Wang, M., Hasebe, M., Fu, J., Goffinet, B., Ma, H., Rensing, S. A., Reski, R., & He, Y.
- Affiliations
- Chinese Academy of Agricultural Sciences (CN)
- Capital Normal University (CN)
- Zhejiang A & F University (CN)
- University of Freiburg (DE)
- Centre National de la Recherche Scientifique (FR)
- University of Bern (CH)
- Philipps University of Marburg (DE)
- Chinese Academy of Sciences (CN)
- Fudan University (CN)
- BGI Group (China) (CN)
- Zhejiang University (CN)
- Hainan University (CN)
- National Institute for Basic Biology (JP)
- University of Guelph (CA)
- University of Connecticut (US)
- Corresponding author
- He, Yikun
- ORCID
- Hu, Ruoyang
- Li, Xuedong
- Hu, Yong
- Lv, Qiang
- Zhang, Min
- Sheng, Xianyong
- Zhao, Feng
- Chen, Zhijia
- Ding, Yuhan
- Yuan, Huan
- Wu, Xiaofeng
- Xing, Shuang
- Yan, Xiaoyu
- Bao, Fang
- Xiao, Lihong
- Wang, Xiaoqin
- Xiao, Wei
- Decker, Eva L.
- van Gessel, Nico
- Renault, Hugues
- Wiedemann, Gertrud
- Haas, Fabian B.
- Wilhelmsson, Per K.I.
- Ullrich, Kristian K.
- Lv, Bin
- Liang, Chengzhi
- Du, Huilong
- Lu, Hongwei
- Gao, Qiang
- Cheng, Zhukuan
- You, Hanli
- Xin, Peiyong
- Chu, Jinfang
- Huang, Chien-Hsun
- Liu, Yang
- Dong, Shanshan
- Zhang, Liangsheng
- Chen, Fei
- Deng, Lei
- Duan, Fuzhou
- Zhao, Wenji
- Li, Kai
- Li, Xingru
- Cui, Hengjian
- Zhang, Yong E.
- Ma, Chuan
- Wang, Meizhi
- Hasebe, Mitsuyasu
- Fu, Jinzhong
- Goffinet, Bernard
- Ma, Hong
- Rensing, Stefan A.
- Reski, Ralf
- He, Yikun
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2023-08
- Volume
- 186
- Issue
- 17
- Pages
- 3558-3576.e17
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W4385697318
- Cited by
- 55
- References
- 154
- Citations by year
- 2026: 10 · 2025: 19 · 2024: 21 · 2023: 5
- FWCI
- 13.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 382 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- BORIS (University Library Bern) (submittedVersion)
- Funders
- Agence Nationale de la Recherche (ANR-19-CE20-0017)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Bryophyte Studies and Records
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- bryophytes, climate change, adaptive evolution, positive selection, UV-B radiation, abiotic stress adaptation, Tibetan Plateau, genome assembly, morphological evolution, extinction risk, uplift
- MeSH terms
- Acclimatization, Adaptation, Physiological, Ecosystem, Tibet, Bryophyta, Climate Change
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