Cited by 55Bryophyte Studies and RecordsGenomics and Phylogenetic StudiesEvolution and Genetic Dynamics

Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet

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Hu, Ruoyang, Li, Xuedong, Hu, Yong, Zhang, Runjie, Lv, Qiang, Zhang, Min, Sheng, Xianyong, Zhao, Feng +53 more·2023·Cell

Abstract

The most extreme environments are the most vulnerable to transformation under a rapidly changing climate. These ecosystems harbor some of the most specialized species, which will likely suffer the highest extinction rates. We document the steepest temperature increase (2010-2021) on record at altitudes of above 4,000 m, triggering a decline of the relictual and highly adapted moss Takakia lepidozioides. Its de-novo-sequenced genome with 27,467 protein-coding genes includes distinct adaptations to abiotic stresses and comprises the largest number of fast-evolving genes under positive selection. The uplift of the study site in the last 65 million years has resulted in life-threatening UV-B radiation and drastically reduced temperatures, and we detected several of the molecular adaptations of Takakia to these environmental changes. Surprisingly, specific morphological features likely occurred earlier than 165 mya in much warmer environments. Following nearly 400 million years of evolution and resilience, this species is now facing extinction.

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Authors
Hu, R., Li, X., Hu, Y., Zhang, R., Lv, Q., Zhang, M., Sheng, X., Zhao, F., Chen, Z., Ding, Y., Yuan, H., Wu, X., Xing, S., Yan, X., Bao, F., Wan, P., Xiao, L., Wang, X., Xiao, W., Decker, E. L., van Gessel, N., Renault, H., Wiedemann, G., Horst, N. A., Haas, F. B., Wilhelmsson, P. K. I., Ullrich, K. K., Neumann, E., Lv, B., Liang, C., Du, H., Lu, H., Gao, Q., Cheng, Z., You, H., Xin, P., Chu, J., Huang, C.-H., Liu, Y., Dong, S., Zhang, L., Chen, F., Deng, L., Duan, F., Zhao, W., Li, K., Li, Z., Li, X., Cui, H., Zhang, Y. E., Ma, C., Zhu, R., Jia, Y., Wang, M., Hasebe, M., Fu, J., Goffinet, B., Ma, H., Rensing, S. A., Reski, R., & He, Y.
Affiliations
  • Chinese Academy of Agricultural Sciences (CN)
  • Capital Normal University (CN)
  • Zhejiang A & F University (CN)
  • University of Freiburg (DE)
  • Centre National de la Recherche Scientifique (FR)
  • University of Bern (CH)
  • Philipps University of Marburg (DE)
  • Chinese Academy of Sciences (CN)
  • Fudan University (CN)
  • BGI Group (China) (CN)
  • Zhejiang University (CN)
  • Hainan University (CN)
  • National Institute for Basic Biology (JP)
  • University of Guelph (CA)
  • University of Connecticut (US)
Corresponding author
He, Yikun
Venue
Cell
Publisher
Elsevier BV
Published
2023-08
Volume
186
Issue
17
Pages
3558-3576.e17
ISSN
0092-8674 (ISSN-L)
OpenAlex
W4385697318
Cited by
55
References
154
Citations by year
2026: 10 · 2025: 19 · 2024: 21 · 2023: 5
FWCI
13.91
Type
journal article
Language
en
Open access
Locations
  • Cell (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion, other-oa)
  • BORIS (University Library Bern) (submittedVersion)
Funders
Agence Nationale de la Recherche (ANR-19-CE20-0017)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Bryophyte Studies and Records
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Keywords
bryophytes, climate change, adaptive evolution, positive selection, UV-B radiation, abiotic stress adaptation, Tibetan Plateau, genome assembly, morphological evolution, extinction risk, uplift
MeSH terms
Acclimatization, Adaptation, Physiological, Ecosystem, Tibet, Bryophyta, Climate Change

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