The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Mechanisms of EHD/RME‐1 Protein Function in Endocytic Transport
Abstract
The evolutionarily conserved Eps15 homology domain (EHD)/receptor‐mediated endocytosis (RME)‐1 family of C‐terminal EH domain proteins has recently come under intense scrutiny because of its importance in intracellular membrane transport, especially with regard to the recycling of receptors from endosomes to the plasma membrane. Recent studies have shed new light on the mode by which these adenosine triphosphatases function on endosomal membranes in mammals and Caenorhabditis elegans. This review highlights our current understanding of the physiological roles of these proteins in vivo, discussing conserved features as well as emerging functional differences between individual mammalian paralogs. In addition, these findings are discussed in light of the identification of novel EHD/RME‐1 protein and lipid interactions and new structural data for proteins in this family, indicating intriguing similarities to the Dynamin superfamily of large guanosine triphosphatases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“the C-terminal EH domain for binding to NPF motifs in a number of proteins18”
From Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development (2016) · cites this paper as [18]
In the citing paper
“The N-terminal G domain of EHD1 is required for ATP binding and membrane recruitment”
From Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development (2016) · cites this paper as [18]
In the citing paper
“the central region for dimerization/oligomerization”
From Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development (2016) · cites this paper as [18]
In the citing paper
“In non-polarized cells, EHD1 (Rme1), EHD3, and EHD4 (pincher) function in endosomes and regulate trafficking through early and recycling endosomes (Grant and Caplan, 2008).”
From Alterations of EHD1/EHD4 Protein Levels Interfere with L1/NgCAM Endocytosis in Neurons and Disrupt Axonal Targeting (2010) · cites this paper as Grant and Caplan, 2008
In the citing paper
“The EHD proteins have a highly conserved domain structure. The N-terminal G domain is required for ATP binding and membrane recruitment, the central region for dimerization/oligomerization, and the C-terminal EH domain for binding to NPF motifs in a number of proteins (Grant and Caplan, 2008).”
From Alterations of EHD1/EHD4 Protein Levels Interfere with L1/NgCAM Endocytosis in Neurons and Disrupt Axonal Targeting (2010) · cites this paper as Grant and Caplan, 2008
In the citing paper
“Endocytosed NgCAM partially overlapped with cytoplasmic puncta of EHD1 and EHD4 staining (Fig. 8B), in agreement with the endosomal localization of EHD1 and EHD4 observed in fibroblasts (Grant and Caplan, 2008).”
From Alterations of EHD1/EHD4 Protein Levels Interfere with L1/NgCAM Endocytosis in Neurons and Disrupt Axonal Targeting (2010) · cites this paper as Grant and Caplan, 2008
In the citing paper
“EHD family members dimerize with themselves and with other members of the EHD family and form higher oligomeric structures which are crucial to their function (Grant and Caplan, 2008).”
From Alterations of EHD1/EHD4 Protein Levels Interfere with L1/NgCAM Endocytosis in Neurons and Disrupt Axonal Targeting (2010) · cites this paper as Grant and Caplan, 2008
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Recycling Endosomes Supply AMPA Receptors for LTP
Park, M., Penick, E. C., Edwards, J. G., Kauer, J. A., & Ehlers, M. D. (2004) · Science · doi:10.1126/science.1102026 · Cited by 730
Galperin, E., Benjamin, S., Rapaport, D., Rotem‐Yehudar, R., Tolchinsky, S., & Horowitz, M. (2002) · Traffic · doi:10.1034/j.1600-0854.2002.30807.x · Cited by 83
EHD1 regulates cholesterol homeostasis and lipid droplet storage
Naslavsky, N., Rahajeng, J., Rapaport, D., Horowitz, M., & Caplan, S. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.04.022 · Cited by 53
Self-citation
Flagged first, then by citations
Research works printed but not linked: 64
- 10.1038/35078549 · DOI
- 10.1242/jcs.02595 · DOI · Paper page
- 10.1038/nature06173 · DOI · Paper page
- 10.1038/351411a0 · DOI
- 10.1128/MCB.13.9.5814 · DOI
- 10.1073/pnas.92.21.9530 · DOI
- 10.1385/CBB:41:2:295 · DOI
- 10.1006/excr.1999.4694 · DOI · Paper page
- Polo S, 2003, EH and UIM: endocytosis and more, Sci STKE, 2003, 10.1126/stke.2132003re17 · DOI
- 10.1126/science.281.5381.1357 · DOI
- 10.1007/s10858-007-9196-0 · DOI
- 10.1093/emboj/17.22.6541 · DOI
- 10.1101/gad.11.17.2239 · DOI · Paper page
- 10.1038/80924 · DOI
- 10.1016/S0014-5793(01)03241-0 · DOI
- 10.1038/sj.emboj.7601980 · DOI
- 10.1091/mbc.e05-01-0076 · DOI · Paper page
- 10.1091/mbc.e03-10-0733 · DOI
- 10.1091/mbc.E05-05-0466 · DOI · Paper page
- 10.1080/09687680410001716871 · DOI · Paper page
- 10.1016/j.cub.2007.10.045 · DOI · Paper page
- 10.1074/jbc.M609493200 · DOI
- 10.1093/emboj/21.11.2557 · DOI · Paper page
- 10.1016/j.yexcr.2006.10.006 · DOI
- 10.1016/0968-0004(90)90281-F · DOI
- 10.1074/jbc.M412751200 · DOI
- 10.1146/annurev.biochem.66.1.639 · DOI
- 10.1038/355733a0 · DOI
- 10.1038/374190a0 · DOI
- 10.1002/bies.950181107 · DOI
- 10.1038/19024 · DOI
- 10.1074/jbc.271.37.22310 · DOI
- 10.1186/1471-2121-8-3 · DOI · Paper page
- 10.1111/j.1600-0854.2008.00732.x · DOI · Paper page
- 10.1038/35078543 · DOI · Paper page
- 10.1242/jcs.03383 · DOI
- 10.1152/ajpcell.00140.2003 · DOI
- 10.1111/j.1600-0854.2005.00359.x · DOI · Paper page
- 10.1091/mbc.e05-08-0787 · DOI · Paper page
- 10.1074/jbc.M307702200 · DOI · Paper page
- 10.1021/bi049970f · DOI
- 10.1074/jbc.M106128200 · DOI
- 10.1083/jcb.200201063 · DOI · Paper page
- 10.1038/nrm1500 · DOI
- 10.1083/jcb.135.4.913 · DOI · Paper page
- 10.1016/0092-8674(92)90307-X · DOI
- 10.1091/mbc.e07-02-0169 · DOI
- 10.1091/mbc.e05-08-0799 · DOI · Paper page
- 10.1091/mbc.E07-09-0902 · DOI
- 10.1111/j.1600-0854.2006.00506.x · DOI · Paper page
- 10.1111/j.1600-0854.2004.00169.x · DOI
- 10.1074/jbc.M301604200 · DOI
- 10.1073/pnas.2133846100 · DOI
- 10.1242/jcs.00395 · DOI
- 10.1091/mbc.10.2.501 · DOI
- 10.1016/j.devcel.2005.11.005 · DOI
- 10.1038/nature04718 · DOI
- 10.1074/jbc.M401918200 · DOI · Paper page
- 10.1074/jbc.M602263200 · DOI
- 10.1091/mbc.E04-01-0026 · DOI
- 10.1038/ncb1627 · DOI
- 10.1111/j.1600-0854.2007.00652.x · DOI · Paper page
- 10.1016/S0006-291X(02)00282-6 · DOI
- 10.1074/jbc.M009913200 · DOI · Paper page
Cited by
Sorted by citations
Posey, A. D., Swanson, K. E., Alvarez, M. G., Krishnan, S., Earley, J. U., Band, H., Pytel, P., McNally, E. M., & Demonbreun, A. R. (2014) · Developmental Biology · doi:10.1016/j.ydbio.2014.01.004 · Cited by 52
Yap, C. C. C., Lasiecka, Z. M., Caplan, S., & Winckler, B. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5428-09.2010 · Cited by 44
Self-citationDifferential regulation of EHD3 in human and mammalian heart failure
Gudmundsson, H., Curran, J., Kashef, F., Snyder, J. S., Smith, S. A., Vargas-Pinto, P., Bonilla, I. M., Weiss, R. M., Anderson, M. E., Binkley, P., et al. (2012) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2012.02.008 · Cited by 37
Bhattacharyya, S., Rainey, M. A., Arya, P., Mohapatra, B. C., Mushtaq, I., Dutta, S., George, M., Storck, M. D., McComb, R. D., Muirhead, D., et al. (2016) · Scientific Reports · doi:10.1038/srep20727 · Cited by 36
Dhawan, K., Naslavsky, N., & Caplan, S. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.011368 · Cited by 36
Self-citation
Metadata
- Authors
- Grant, B. D., & Caplan, S.
- Venue
- Traffic
- Publisher
- Wiley
- Published
- 2008-11-20
- Volume
- 9
- Issue
- 12
- Pages
- 2043-2052
- ISSN
- 1398-9219
- 1600-0854
- PMC
- PMC2766864
- Cited by
- 137
- References
- 3
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
