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Liddiard, K., Ruis, B. L., Takasugi, T., Harvey, A., Ashelford, K. E., Hendrickson, E. A., & Baird, D. M. (2016) · Genome Research · doi:10.1101/gr.200840.115 · Cited by 47 · see citing works

Telomeres as hotspots for innate immunity and inflammation

Nassour, J., Przetocka, S., & Karlseder, J. (2023) · DNA repair · doi:10.1016/j.dnarep.2023.103591 · Cited by 40 · see citing works

Ligase-4 Deficiency Causes Distinctive Immune Abnormalities in Asymptomatic Individuals

Felgentreff, K., Baxi, S. N., Lee, Y. N., Dobbs, K., Henderson, L. A., Csomós, K., Tsitsikov, E. N., Armanios, M. Y., Walter, J. E., & Notarangelo, L. D. (2016) · Journal of Clinical Immunology · doi:10.1007/s10875-016-0266-5 · Cited by 38 · see citing works

High-throughput STELA provides a rapid test for the diagnosis of telomere biology disorders

Norris, K., Walne, A. J., Ponsford, M., Cleal, K., Grimstead, J. W., Ellison, A., Alnajar, J., Dokal, I. S., Vulliamy, T., & Baird, D. M. (2021) · Human Genetics · doi:10.1007/s00439-021-02257-4 · Cited by 36 · see citing works

Alternative Okazaki Fragment Ligation Pathway by DNA Ligase III

Arakawa, H., & Iliakis, G. E. (2015) · Genes · doi:10.3390/genes6020385 · Cited by 34 · see citing works

Telomere length is a critical determinant for survival in multiple myeloma

Hyatt, S., Jones, R. E., Heppel, N. H., Grimstead, J. W., Fegan, C., Jackson, G. H., Hills, R. K., Allan, J. M., Pratt, G., Pepper, C. J., et al. (2017) · British Journal of Haematology · doi:10.1111/bjh.14643 · Cited by 30 · see citing works

Chromothripsis and telomere crisis: engines of genome instability

Dewhurst, S. M. (2020) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2020.02.009 · Cited by 27 · see citing works

DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase

Liddiard, K., Ruis, B. L., Kan, Y., Cleal, K., Ashelford, K. E., Hendrickson, E. A., & Baird, D. M. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky1279 · Cited by 28 · see citing works

SMCHD1 promotes ATM‐dependent DNA damage signaling and repair of uncapped telomeres

Vančevska, A., Ahmed, W., Pfeiffer, V., Feretzaki, M., Boulton, S. J., & Lingner, J. (2020) · The EMBO Journal · doi:10.15252/embj.2019102668 · Cited by 25 · see citing works

Telomere length heterogeneity in placenta revealed with high-resolution telomere length analysis

García-Martín, I., Janssen, A. B., Jones, R. E., Grimstead, J. W., Penketh, R., Baird, D. M., & John, R. M. (2017) · Placenta · doi:10.1016/j.placenta.2017.09.007 · Cited by 25 · see citing works

The DNA damage response at dysfunctional telomeres, and at interstitial and subtelomeric DNA double-strand breaks

Muraki, K., & Murnane, J. P. (2017) · Genes & Genetic Systems · doi:10.1266/ggs.17-00014 · Cited by 23 · see citing works

Genome rearrangements associated with aberrant telomere maintenance

Bhargava, R., Fischer, M., & O’Sullivan, R. J. (2020) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2020.02.005 · Cited by 22 · see citing works

hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells

Romaniuk-Drapała, A., Totoń, E., Konieczna, N., Machnik, M., Barczak, W., Kowal, D., Kopczyński, P., Kaczmarek, M., & Rubiś, B. (2021) · Cells · doi:10.3390/cells10040867 · Cited by 22 · see citing works

Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1

Majerská, J., Feretzaki, M., Glousker, G., & Lingner, J. (2018) · Life Science Alliance · doi:10.26508/lsa.201800121 · Cited by 20 · see citing works

Telomere fusions and translocations: a bridge too far?

Stroik, S., & Hendrickson, E. A. (2020) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2020.02.010 · Cited by 20 · see citing works

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ

Harvey, A., Mielke, N., Grimstead, J. W., Jones, R. E., Nguyen, T., Mueller, M. R., Baird, D. M., & Hendrickson, E. A. (2018) · Oncotarget · doi:10.18632/oncotarget.26201 · Cited by 17 · see citing works

How homologous recombination maintains telomere integrity

Tacconi, E. M., & Tarsounas, M. (2014) · Chromosoma · doi:10.1007/s00412-014-0497-2 · Cited by 17 · see citing works

Kinetic analyses of single-stranded break repair by human DNA ligase III isoforms reveal biochemical differences from DNA ligase I

McNally, J., & O’Brien, P. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.804625 · Cited by 16 · see citing works

POLQ suppresses genome instability and alterations in DNA repeat tract lengths

Liddiard, K., Aston, A. N., Cleal, K., Hendrickson, E. A., & Baird, D. M. (2022) · NAR Cancer · doi:10.1093/narcan/zcac020 · Cited by 15 · see citing works

To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks

Casari, E., Gnugnoli, M., Rinaldi, C., Pizzul, P., Colombo, C. V., Bonetti, D., & Longhese, M. P. (2022) · Cells · doi:10.3390/cells11203224 · Cited by 17 · see citing works

Association of Telomere Length with Colorectal Cancer Risk and Prognosis: A Systematic Review and Meta-Analysis

Pauleck, S., Sinnott, J. A., Zheng, Y., Gadalla, S. M., Viskochil, R. H., Haaland, B. A., Cawthon, R., Hoffmeister, A., & Hardikar, S. S. (2023) · Cancers · doi:10.3390/cancers15041159 · Cited by 12 · see citing works

Telomere erosion in NF1 tumorigenesis

Jones, R. E., Grimstead, J. W., Sedani, A., Baird, D. M., & Upadhyaya, M. (2017) · Oncotarget · doi:10.18632/oncotarget.16981 · Cited by 11 · see citing works

Telomere Crisis Shapes Cancer EvolutionPreprint

Nassour, J., & Karlseder, J. (2025) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041688 · Cited by 13 · see citing works

Chromosome instability induced by a single defined sister chromatid fusion

Kagaya, K., Noma-Takayasu, N., Yamamoto, I., Tashiro, S., Ishikawa, F., & Hayashi, M. (2020) · Life Science Alliance · doi:10.26508/lsa.202000911 · Cited by 10 · see citing works

ATRX modulates the escape from a telomere crisis

Geiller, H. E. B., Harvey, A., Jones, R. E., Grimstead, J. W., Cleal, K., Hendrickson, E. A., & Baird, D. M. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010485 · Cited by 10 · see citing works

Extensive telomere erosion is consistent with localised clonal expansions in Barrett’s metaplasia

Letsolo, B. T., Jones, R. E., Rowson, J., Grimstead, J. W., Keith, W. N., Jenkins, G. J. S., & Baird, D. M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0174833 · Cited by 9 · see citing works

PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation

Ngo, H.-P., Hyatt, S., Grimstead, J. W., Jones, R. E., Hendrickson, E. A., Pepper, C. J., & Baird, D. M. (2018) · Oncotarget · doi:10.18632/oncotarget.26499 · Cited by 9 · see citing works

Stretching, scrambling, piercing and entangling: Challenges for telomeres in mitotic and meiotic chromosome segregation

Hou, H., & Cooper, J. P. (2018) · Differentiation · doi:10.1016/j.diff.2018.01.002 · Cited by 8 · see citing works

Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA damage response

Liddiard, K., Grimstead, J. W., Cleal, K., Evans, A., & Baird, D. M. (2021) · NAR Cancer · doi:10.1093/narcan/zcaa044 · Cited by 7 · see citing works

Parent and Metabolite Concentration-QT Modeling to Evaluate QT-Interval Prolongation at Savolitinib Therapeutic Doses

Schalkwijk, S. J., Sahota, T., Verheijen, R. B., Harmer, A. R., & Ahmed, G. F. (2021) · The AAPS Journal · doi:10.1208/s12248-021-00573-1 · Cited by 8 · see citing works

Telomeres and Chromosomal Translocations : There's a Ligase at the End of the Translocation.

Baird, D., & Hendrickson, E. (2018) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-13-0593-1_7 · Cited by 6 · see citing works

Telomere length profiles in primary human peritoneal mesothelial cells are consistent with senescence

Lopez-Anton, M., Rudolf, A. H., Baird, D. M., Roger, L., Jones, R. E., Witowski, J., Fraser, D. J., & Bowen, T. (2017) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2017.03.010 · Cited by 7 · see citing works

The absence of (TCAGGG)n repeats in some telomeres, combined with variable responses to NR2F2 depletion, suggest that this nuclear receptor plays an indirect role in the alternative lengthening of telomeres

Alhendi, A. S. N., & Royle, N. J. (2020) · Scientific Reports · doi:10.1038/s41598-020-77606-w · Cited by 7 · see citing works

Telomere Dynamics in Human Health and DiseasePreprint

Baird, D. M. (2024) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041701 · Cited by 6 · see citing works

In vitro assessment of the antioxidative, toxicological and antimicrobial properties of battery of parabens

Katavic, S., Cehic, I., Zukic, N., Mirvic, M., Dizdar, M., Gutalj, A., Medić, B. Š., Jerković-Mujkić, A., Mahmutović-Dizdarević, I., & Mešić, A. (2023) · Drug and Chemical Toxicology · doi:10.1080/01480545.2023.2222928 · Cited by 5 · see citing works

LINE retrotransposition and host DNA repair machinery

YAMAGUCHI, K., Kajikawa, M., & Okada, N. (2015) · Mobile Genetic Elements · doi:10.1080/2159256x.2015.1096998 · Cited by 5 · see citing works

Both the classical and alternative non-homologous end joining pathways contribute to the fusion of drastically shortened telomeres induced by TRF2 overexpression

Nera, B., Huang, H.-S., Hendrickson, E. A., & Xu, L. (2019) · Cell Cycle · doi:10.1080/15384101.2019.1598724 · Cited by 5 · see citing works

Telomerase-independent survival leads to a mosaic of complex subtelomere rearrangements in Chlamydomonas reinhardtiiPreprint

Chaux, F., Agier, N., Garrido, C., Fischer, G., Eberhard, S., & Xu, Z. (2023) · Genome Research · doi:10.1101/gr.278043.123 · Cited by 5 · see citing works

A patent review of DNA polymerase theta (Polθ) targeted therapies (2019–2025)

Ma, L., Luo, M., Xiang, H., & Luo, G. (2026) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2026.2614484 · Cited by 4 · see citing works

The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional TelomeresPreprint

Billing, D. L., & Sfeir, A. J. (2024) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a041687 · Cited by 4 · see citing works

Benzothiazole Derivatives Targeting G‐Quadruplex DNA: Synthesis, DNA Interaction and Living Cell Imaging

Wei, C., & Li, H. (2022) · ChemistrySelect · doi:10.1002/slct.202202565 · Cited by 3 · see citing works

Alternative end joining, clonal evolution, and escape from a telomere-driven crisis

Hendrickson, E. A., & Baird, D. M. (2015) · Molecular & Cellular Oncology · doi:10.4161/23723556.2014.975623 · Cited by 3 · see citing works

Effect of DNA repair inhibitor AsiDNA on the incidence of telomere fusion in crisis

Subecz, C., Sun, J., & Roger, L. (2021) · Human Molecular Genetics · doi:10.1093/hmg/ddab008 · Cited by 2 · see citing works

Repair pathway choice at dysfunctional telomeres

Gillespie, A., & Nassour, J. (2026) · Trends in Cell Biology · doi:10.1016/j.tcb.2026.04.006 · Cited by 1 · see citing works

Telomere Length in Cystic Fibrosis Patients – Are Patients with CF Ageing Too Quickly?

Ashworth, I., Norris, K., Thia, L. P., Dodge, J. A., Grimstead, J. W., Jones, R. E., Forton, J. T., Smith, A., Farewell, D., Baird, D. M., et al. (2021) · International Journal of Aging Research · doi:10.28933/ijoar-2021-06-2005 · Cited by 1 · see citing works

Alternative Okazaki Fragment Ligation Pathway by

Arakawa, H., Iliakis, G. E., & Frank, P. H. (2015)

Faculty Opinions recommendation of Telomeres in cancer: tumour suppression and genome instability.

Savage, S. A. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.727224887.793545187

Crucial role of telomere maintenance-related genes in survival prediction and subtype identification in colorectal cancer

Huang, F., Zhao, W. G., Li, Z. Y., Fong, J. Y., Okechukwu, P. N., Ng, C. T., Venkatachalam, K., Alshawsh, M. A., Letchumanan, V., & Selvaraja, M. (2026) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2026.1728178

An Orally Available Telomeric G-Quadruplex Ligand Induces Telomere Crisis and Dual DNA/RNA-Sensing Innate Immunity for Cancer Therapy

Cai, J.-H., Shi, Y., Yang, D.-Y., Huang, W., Liu, Y., Zhong, L., Zhang, J.-J., Gong, Z., Lü, Y.-Y., Lin, J., et al. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c03148

Alternative end joining, clonal evolution, and escape from a telomere-driven crisis

Hendrickson, E. A., & Baird, D. M. (2015) · Molecular & Cellular Oncology · doi:10.4161/23723556.2014.975623 · Cited by 3 · see citing works

Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4Preprint

Liddiard, K., Ruis, B. L., Takasugi, T., Harvey, A., Ashelford, K. E., Hendrickson, E. A., & Baird, D. M. (2016) · Genome Research · doi:10.1101/gr.200840.115 · Cited by 47 · see citing works

Both the classical and alternative non-homologous end joining pathways contribute to the fusion of drastically shortened telomeres induced by TRF2 overexpression

Nera, B., Huang, H.-S., Hendrickson, E. A., & Xu, L. (2019) · Cell Cycle · doi:10.1080/15384101.2019.1598724 · Cited by 5 · see citing works

DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2

Smogorzewska, A., Karlseder, J., Holtgreve-Grez, H., Jauch, A. S., & de Lange, T. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01179-x · Cited by 377 · see citing works

Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV

Heacock, M. L., Idol, R. A., Friesner, J. D., Britt, A., & Shippen, D. E. (2007) · Nucleic Acids Research · doi:10.1093/nar/gkm472 · Cited by 68 · see citing works