CoChat
Sign Up
Cited by 38

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis

Lee, Jeesan, Villarreal, Oscar David, Chen, Xiaoru, Zandee, Stéphanie, Young, Yoon Kow, Torok, Cynthia, Lamarche-Vane, Nathalie, Prat, Alexandre, Rivest, Serge, Gosselin, David, Richard, Stéphane·2020·Cell Reports
DOI 10.1016/j.celrep.2020.108560
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.celrep.2020.108560

Cites

15 of 15 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 15 references

Research works printed but not linked: 54

  1. Aberg, 2006, Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia, Proc. Natl. Acad. Sci. USA, 103, 7482, 10.1073/pnas.0601213103 · DOI · Paper page
  2. Anwar, 2004, RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65, J. Immunol., 173, 6965, 10.4049/jimmunol.173.11.6965 · DOI
  3. Baaklini, 2019, Central Nervous System Remyelination: Roles of Glia and Innate Immune Cells, Front. Mol. Neurosci., 12, 225, 10.3389/fnmol.2019.00225 · DOI
  4. Caron, 1998, Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases, Science, 282, 1717, 10.1126/science.282.5394.1717 · DOI · Paper page
  5. Chen, 2013, Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool, BMC Bioinformatics, 14, 128, 10.1186/1471-2105-14-128 · DOI · Paper page
  6. Cooper, 2009, RNA and disease, Cell, 136, 777, 10.1016/j.cell.2009.02.011 · DOI
  7. Corley, 2020, How RNA-Binding Proteins Interact with RNA: Molecules and Mechanisms, Mol. Cell, 78, 9, 10.1016/j.molcel.2020.03.011 · DOI
  8. Darbelli, 2016, Emerging functions of the Quaking RNA-binding proteins and link to human diseases, Wiley Interdiscip. Rev. RNA, 7, 399, 10.1002/wrna.1344 · DOI
  9. Darbelli, 2016, Quaking Regulates Neurofascin 155 Expression for Myelin and Axoglial Junction Maintenance, J. Neurosci., 36, 4106, 10.1523/JNEUROSCI.3529-15.2016 · DOI
  10. Darbelli, 2017, Transcriptome profiling of mouse brains with qkI-deficient oligodendrocytes reveals major alternative splicing defects including self-splicing, Sci. Rep., 7, 7554, 10.1038/s41598-017-06211-1 · DOI
  11. David, 2012, Cell cycle regulation of Rho signaling pathways, Cell Cycle, 11, 3003, 10.4161/cc.21088 · DOI
  12. de Bruin, 2016, Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression, Nat. Commun., 7, 10846, 10.1038/ncomms10846 · DOI
  13. de Hoon, 2004, Open source clustering software, Bioinformatics, 20, 1453, 10.1093/bioinformatics/bth078 · DOI
  14. Dhaeze, 2019, CD70 defines a subset of proinflammatory and CNS-pathogenic TH1/TH17 lymphocytes and is overexpressed in multiple sclerosis, Cell. Mol. Immunol., 16, 652, 10.1038/s41423-018-0198-5 · DOI
  15. Fani Maleki, 2019, Innate Immune Cells: Monocytes, Monocyte-Derived Macrophages and Microglia as Therapeutic Targets for Alzheimer’s Disease and Multiple Sclerosis, Front. Cell. Neurosci., 13, 355, 10.3389/fncel.2019.00355 · DOI
  16. Farnsworth, 2016, Gene Expression of Quaking in Sporadic Alzheimer’s Disease Patients is Both Upregulated and Related to Expression Levels of Genes Involved in Amyloid Plaque and Neurofibrillary Tangle Formation, J. Alzheimers Dis., 53, 209, 10.3233/JAD-160160 · DOI
  17. Frankish, 2019, GENCODE reference annotation for the human and mouse genomes, Nucleic Acids Res., 47, D766, 10.1093/nar/gky955 · DOI
  18. Galarneau, 2005, Target RNA motif and target mRNAs of the Quaking STAR protein, Nat. Struct. Mol. Biol., 12, 691, 10.1038/nsmb963 · DOI
  19. Goldmann, 2013, A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation, Nat. Neurosci., 16, 1618, 10.1038/nn.3531 · DOI · Paper page
  20. Gonatopoulos-Pournatzis, 2020, Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions, Mol. Cell, 77, 1176, 10.1016/j.molcel.2020.01.006 · DOI
  21. Gosselin, 2014, Environment drives selection and function of enhancers controlling tissue-specific macrophage identities, Cell, 159, 1327, 10.1016/j.cell.2014.11.023 · DOI · Paper page
  22. Gu, 2016, Complex heatmaps reveal patterns and correlations in multidimensional genomic data, Bioinformatics, 32, 2847, 10.1093/bioinformatics/btw313 · DOI
  23. Hall, 2013, Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation, RNA, 19, 627, 10.1261/rna.038422.113 · DOI
  24. Hanley, 2010, Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility, Proc. Natl. Acad. Sci. USA, 107, 12145, 10.1073/pnas.0911986107 · DOI
  25. Heinz, 2010, Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities, Mol. Cell, 38, 576, 10.1016/j.molcel.2010.05.004 · DOI · Paper page
  26. Huang, 2009, Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nat. Protoc., 4, 44, 10.1038/nprot.2008.211 · DOI · Paper page
  27. Itoh, 2012, Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-myosin II signaling, Proc. Natl. Acad. Sci. USA, 109, 9905, 10.1073/pnas.1115063109 · DOI
  28. Kapellos, 2016, A novel real time imaging platform to quantify macrophage phagocytosis, Biochem. Pharmacol., 116, 107, 10.1016/j.bcp.2016.07.011 · DOI · Paper page
  29. Keren-Shaul, 2017, A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease, Cell, 169, 1276, 10.1016/j.cell.2017.05.018 · DOI · Paper page
  30. Kitzing, 2007, Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion, Genes Dev., 21, 1478, 10.1101/gad.424807 · DOI
  31. Kuleshov, 2016, Enrichr: a comprehensive gene set enrichment analysis web server 2016 update, Nucleic Acids Res., 44, W90, 10.1093/nar/gkw377 · DOI · Paper page
  32. Lavon, 2019, QKI-V5 is downregulated in CNS inflammatory demyelinating diseases, Mult. Scler. Relat. Disord., 39, 101881, 10.1016/j.msard.2019.101881 · DOI
  33. Li, 2015, RBFOX and PTBP1 proteins regulate the alternative splicing of micro-exons in human brain transcripts, Genome Res., 25, 1, 10.1101/gr.181990.114 · DOI
  34. Love, 2014, Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2, Genome Biol., 15, 550, 10.1186/s13059-014-0550-8 · DOI · Paper page
  35. Lukong, 2008, RNA-binding proteins in human genetic disease, Trends Genet., 24, 416, 10.1016/j.tig.2008.05.004 · DOI
  36. Masaki, 2020, RNA-binding protein altered expression and mislocalization in MS, Neurol. Neuroimmunol. Neuroinflamm., 7, e704, 10.1212/NXI.0000000000000704 · DOI
  37. Pillman, 2018, miR-200/375 control epithelial plasticity-associated alternative splicing by repressing the RNA-binding protein Quaking, EMBO J., 37, e99016, 10.15252/embj.201899016 · DOI
  38. Polman, 2011, Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria, Ann. Neurol., 69, 292, 10.1002/ana.22366 · DOI · Paper page
  39. Qi, 2020, The chemokine CCL7 regulates invadopodia maturation and MMP-9 mediated collagen degradation in liver-metastatic carcinoma cells, Cancer Lett., 483, 98, 10.1016/j.canlet.2020.03.018 · DOI
  40. Robinson, 2011, Integrative genomics viewer, Nat. Biotechnol., 29, 24, 10.1038/nbt.1754 · DOI · Paper page
  41. Roser, 2017, Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson’s Disease and Amyotrophic Lateral Sclerosis, Front. Aging Neurosci., 9, 94, 10.3389/fnagi.2017.00094 · DOI · Paper page
  42. Saldanha, 2004, Java Treeview--extensible visualization of microarray data, Bioinformatics, 20, 3246, 10.1093/bioinformatics/bth349 · DOI
  43. Salter, 2017, Microglia emerge as central players in brain disease, Nat. Med., 23, 1018, 10.1038/nm.4397 · DOI · Paper page
  44. Shen, 2014, rMATS: robust and flexible detection of differential alternative splicing from replicate RNA-Seq data, Proc. Natl. Acad. Sci. USA, 111, E5593, 10.1073/pnas.1419161111 · DOI · Paper page
  45. Shen, 2016, The Rag-Ragulator Complex Regulates Lysosome Function and Phagocytic Flux in Microglia, Cell Rep., 14, 547, 10.1016/j.celrep.2015.12.055 · DOI
  46. Shingu, 2017, Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation, Nat. Genet., 49, 75, 10.1038/ng.3711 · DOI
  47. Socodato, 2020, Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration, Cell Rep., 31, 107796, 10.1016/j.celrep.2020.107796 · DOI · Paper page
  48. Tönges, 2011, ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration, Front. Mol. Neurosci., 4, 39, 10.3389/fnmol.2011.00039 · DOI
  49. Ule, 2019, Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution, Mol. Cell, 76, 329, 10.1016/j.molcel.2019.09.017 · DOI · Paper page
  50. van der Veer, 2013, Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype, Circ. Res., 113, 1065, 10.1161/CIRCRESAHA.113.301302 · DOI
  51. Vaquero-Garcia, 2016, A new view of transcriptome complexity and regulation through the lens of local splicing variations, eLife, 5, e11752, 10.7554/eLife.11752 · DOI · Paper page
  52. Yokoo, 2004, Anti-human Olig2 antibody as a useful immunohistochemical marker of normal oligodendrocytes and gliomas, Am. J. Pathol., 164, 1717, 10.1016/S0002-9440(10)63730-3 · DOI
  53. Zhang, 2008, Lesional accumulation of RhoA(+) cells in brains of experimental autoimmune encephalomyelitis and multiple sclerosis, Neuropathol. Appl. Neurobiol., 34, 231, 10.1111/j.1365-2990.2007.00892.x · DOI
  54. Zong, 2014, The RNA-binding protein QKI suppresses cancer-associated aberrant splicing, PLoS Genet., 10, e1004289, 10.1371/journal.pgen.1004289 · DOI

Cited by

Sorted by citations

See all 38

Metadata

Authors
Lee, J., Villarreal, O. D., Chen, X., Zandee, S., Young, Y. K., Torok, C., Lamarche-Vane, N., Prat, A., Rivest, S., Gosselin, D., & Richard, S.
Venue
Cell Reports
Publisher
Elsevier BV
Published
2020-12
Volume
33
Issue
13
Pages
108560
ISSN
2211-1247
DOI
10.1016/j.celrep.2020.108560
Cited by
38
References
15
Language
en
Licence
Funders
Canadian Institutes of Health Research

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review