A Comparison of the Quick-SOFA and Systemic Inflammatory Response Syndrome Criteria for the Diagnosis of Sepsis and Prediction of Mortality

The third international consensus definitions for sepsis and septic shock (Sepsis-3).

Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J.-D., Coopersmith, C. M., et al. (2016) · JAMA · doi:10.1001/jama.2016.0287 · Cited by 28,250 · see citing works

The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164 · see citing works

Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>

Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623 · see citing works

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

Bone, R. C., BALK, R. A., Cerra, F. B., Dellinger, R. P., Fein, A. M., Knaus, W. A., Schein, R. M. H., & Sibbald, W. J. (1992) · CHEST Journal · doi:10.1378/chest.101.6.1644 · Cited by 13,192 · see citing works

The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration

Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.006 · Cited by 10,578 · see citing works

Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

Seymour, C. W., Liu, V. X., Iwashyna, T. J., Brunkhorst, F. M., Rea, T. D., Scherag, A., Rubenfeld, G., Kahn, J. M., Shankar-Hari, M., Singer, M., et al. (2016) · JAMA · doi:10.1001/jama.2016.0288 · Cited by 3,939 · see citing works

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

Conference, F. T. I. S. D., Levy, M. M., Fink, M. P., Marshall, J. C., Abraham, E. H., Angus, D. C., Cook, D., Cohen, J., Opal, S. M., Vincent, J., et al. (2003) · Intensive Care Medicine · doi:10.1007/s00134-003-1662-x · Cited by 2,877 · see citing works

Prognostic accuracy of the SOFA score, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit

Raith, E. P., Udy, A. A., Bailey, M., McGloughlin, S., MacIsaac, C., Bellomo, R., Pilcher, D. V., & for the Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcomes and Resource Evaluation (CORE) (2017) · JAMA · doi:10.1001/jama.2016.20328 · Cited by 1,279 · see citing works

Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy A Randomized Clinical Trial

Jones, A. E. (2010) · JAMA · doi:10.1001/jama.2010.158 · Cited by 1,076 · see citing works

Prognostic Accuracy of Sepsis-3 Criteria for In-Hospital Mortality Among Patients With Suspected Infection Presenting to the Emergency Department

Freund, Y., Lemachatti, N., Krastinova, E., Laer, M. V., Claessens, Y.-É., Avondo, A., Occelli, C., Féral‐Pierssens, A., Truchot, J., Ortega, M., et al. (2017) · JAMA · doi:10.1001/jama.2016.20329 · Cited by 708 · see citing works

Quick sepsis-related organ failure assessment, systemic inflammatory response syndrome, and early warning scores for detecting clinical deterioration in infected patients outside the intensive care unit

Churpek, M. M., Snyder, A., Han, X., Sokol, S., Pettit, N., Howell, M. D., & Edelson, D. P. (2017) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201604-0854oc · Cited by 689 · see citing works

Systemic Inflammatory Response Syndrome, Quick Sequential Organ Function Assessment, and Organ Dysfunction

Williams, J. M., Greenslade, J. H., McKenzie, J. V., Chu, K., Brown, A. F., & Lipman, J. (2016) · CHEST Journal · doi:10.1016/j.chest.2016.10.057 · Cited by 293 · see citing works

Confidence Limits Made Easy: Interval Estimation Using a Substitution Method

Daly, L. (1998) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009523 · Cited by 289 · see citing works

Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality – a prospective study of patients admitted with infection to the emergency department

Askim, Å., Moser, F., Gustad, L. T., Stene, H., Gundersen, M., Åsvold, B. O., Dale, J., Bjørnsen, L. P., Damås, J. K., & Solligård, E. (2017) · Scandinavian Journal of Trauma Resuscitation and Emergency Medicine · doi:10.1186/s13049-017-0399-4 · Cited by 247 · see citing works

Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit

Finkelsztein, E. J., Jones, D. S., Ma, K. C., Pabón, M. A., Delgado, T., Nakahira, K., Arbo, J. E., Berlin, D., Schenck, E. J., Choi, A. M. K., et al. (2017) · Critical Care · doi:10.1186/s13054-017-1658-5 · Cited by 231 · see citing works

New Sepsis Criteria

Simpson, S. Q. (2016) · CHEST Journal · doi:10.1016/j.chest.2016.02.653 · Cited by 215 · see citing works

qSOFA Has Poor Sensitivity for Prehospital Identification of Severe Sepsis and Septic Shock

Dorsett, M., Kroll, M., Smith, C. S., Asaro, P. V., Liang, S. Y., & Moy, H. P. (2017) · Prehospital Emergency Care · doi:10.1080/10903127.2016.1274348 · Cited by 119 · see citing works

Application of the Third International Consensus Definitions for Sepsis (Sepsis-3) Classification: a retrospective population-based cohort study

Donnelly, J. P., Safford, M. M., Shapiro, N. I., Baddley, J. W., & Wang, H. E. (2017) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(17)30117-2 · Cited by 119 · see citing works

One year mortality of patients treated with an emergency department based early goal directed therapy protocol for severe sepsis and septic shock: a before and after study

Puskarich, M. A., Marchick, M. R., Kline, J. A., Steuerwald, M., & Jones, A. E. (2009) · Critical Care · doi:10.1186/cc8138 · Cited by 117 · see citing works

The Impact of the Sepsis-3 Septic Shock Definition on Previously Defined Septic Shock Patients*

Sterling, S. A., Puskarich, M. A., Glass, A. F., Guirgis, F. W., & Jones, A. E. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002512 · Cited by 91 · see citing works

O pening the D ebate on the N ew S epsis D efinition Change Is Not Necessarily Progress: Revision of the Sepsis Definition Should Be Based on New Scientific Insights

Cortés‐Puch, I., & Hartog, C. S. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201604-0734ed · Cited by 76 · see citing works

Sepsis Clinical Criteria in Emergency Department Patients Admitted to an Intensive Care Unit: An External Validation Study of Quick Sequential Organ Failure Assessment

April, M. D., Aguirre, J., Tannenbaum, L., Moore, T. M., Pingree, A., Thaxton, R. E., Sessions, D. J., & Lantry, J. H. (2016) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2016.10.012 · Cited by 73 · see citing works

Influence of vasopressor agent in septic shock mortality. Results from the Portuguese Community-Acquired Sepsis Study (SACiUCI study)*

Póvoa, P. M. S. R., Carneiro, A., Ribeiro, O., & Costa‐Pereira, A. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181958b1c · Cited by 71 · see citing works

Quick sequential organ failure assessment compared to systemic inflammatory response syndrome for predicting sepsis in emergency department

Park, H., Kim, W. Y., Kim, M. C., Jung, W., & Ko, B. S. (2017) · Journal of Critical Care · doi:10.1016/j.jcrc.2017.06.020 · Cited by 63 · see citing works

Systemic Inflammatory Response Syndrome Criteria for Severe Sepsis

Kaukonen, K.-M., Bailey, M., & Bellomo, R. (2015) · New England Journal of Medicine · doi:10.1056/nejmc1506819 · Cited by 61 · see citing works

Dear Sepsis-3, we are sorry to say that we don’t like you

Carneiro, A. H., Póvoa, P. M. S. R., & Gomes, J. A. (2017) · Revista Brasileira de Terapia Intensiva · doi:10.5935/0103-507x.20170002 · Cited by 57 · see citing works

Predictors of Patients Who Present to the Emergency Department With Sepsis and Progress to Septic Shock Between 4 and 48 Hours of Emergency Department Arrival*

Capp, R., Horton, C. L., Takhar, S. S., Ginde, A. A., Peak, D. A., Zane, R. D., & Marill, K. A. (2015) · Critical Care Medicine · doi:10.1097/ccm.0000000000000861 · Cited by 56 · see citing works

The new sepsis consensus definitions: the good, the bad and the ugly

Sprung, C. L., Schein, R. M. H., & BALK, R. A. (2016) · Intensive Care Medicine · doi:10.1007/s00134-016-4604-0 · Cited by 54 · see citing works

Impact of an electronic sepsis initiative on antibiotic use and health care facility–onset Clostridium difficile infection rates

Hiensch, R., Poeran, J., Saunders-Hao, P., Adams, V., Powell, C. A., Glasser, A., Mazumdar, M., & Patel, G. (2017) · American Journal of Infection Control · doi:10.1016/j.ajic.2017.04.005 · Cited by 44 · see citing works

A comparison of pre ICU admission SIRS, EWS and q SOFA scores for predicting mortality and length of stay in ICU

Siddiqui, S., Chua, M., Venkatesan, K., & Choo, R. W. M. (2017) · Journal of Critical Care · doi:10.1016/j.jcrc.2017.05.017 · Cited by 38 · see citing works

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.

Evans, L., Rhodes, A., Alhazzani, W., Antonelli, M., Coopersmith, C. M., French, C., Machado, F. R., Mcintyre, L., Ostermann, M., Prescott, H. C., et al. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005337 · Cited by 2,935 · see citing works

Machine learning for the prediction of sepsis: a systematic review and meta-analysis of diagnostic test accuracy

Fleuren, L. M., Klausch, T. L. T., Zwager, C. L., Schoonmade, L. J., Guo, T., Roggeveen, L. F., Swart, E. L., Girbes, A. R. J., Thoral, P., Ercole, A., et al. (2020) · Intensive Care Medicine · doi:10.1007/s00134-019-05872-y · Cited by 755 · see citing works

Sepsis: evolving concepts and challenges

Salomão, R., Ferreira, B. L., Salomão, M. C., Santos, S. S., Azevedo, L. C. P., & Brunialti, M. K. C. (2019) · Brazilian Journal of Medical and Biological Research · doi:10.1590/1414-431x20198595 · Cited by 362 · see citing works

Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries

Rudd, K. E., Seymour, C. W., Aluisio, A. R., Augustin, M. E., Bagenda, D. S., Beane, A., Byiringiro, J. C., Chang, C.-C. H., Colas, L. N., Day, N., et al. (2018) · JAMA · doi:10.1001/jama.2018.6229 · Cited by 227 · see citing works

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

Egi, M., Ogura, H., Yatabe, T., Atagi, K., Inoue, S., Iba, T., Kakihana, Y., Kawasaki, T., Kushimoto, S., Kuroda, Y., et al. (2021) · Journal of Intensive Care · doi:10.1186/s40560-021-00555-7 · Cited by 226 · see citing works

Sepsis: key insights, future directions, and immediate goals. A review and expert opinion

Martín‐Loeches, I., Singer, M., & Léone, M. (2024) · Intensive Care Medicine · doi:10.1007/s00134-024-07694-z · Cited by 190 · see citing works

Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients*

Crouser, E. D., Parrillo, J. E., Seymour, C. W., Angus, D. C., Bicking, K., Esguerra, V. G., Peck‐Palmer, O. M., Magari, R. T., JULIAN, M. W., Kleven, J. M., et al. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000003799 · Cited by 169 · see citing works

SIRS, SOFA, qSOFA, and NEWS in the diagnosis of sepsis and prediction of adverse outcomes: a systematic review and meta-analysis

Qiu, X., Lei, Y.-H., & Zhou, R.-X. (2023) · Expert Review of Anti-Infective Therapy · doi:10.1080/14787210.2023.2237192 · Cited by 146 · see citing works

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

Evans, L., Rhodes, A., Alhazzani, W., Antonelli, M., Coopersmith, C. M., French, C., Machado, F. R., Mcintyre, L., Ostermann, M., Prescott, H. C., et al. (2021) · Intensive Care Medicine · doi:10.1007/s00134-021-06506-y · Cited by 5,082 · see citing works

Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026

Prescott, H. C., Antonelli, M. M., Alhazzani, W. A., Møller, M. H., Alshamsi, F. E., Azevedo, L. C. P., Belley‐Côté, E. P., Waele, J. D., Derde, L. P. G., Dionne, J. C., et al. (2026) · Intensive Care Medicine · doi:10.1007/s00134-026-08361-1 · Cited by 134 · see citing works

Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA

Crouser, E. D., Parrillo, J. E., Martin, G. S., Huang, D. T., Hausfater, P., Grigorov, I. L., Careaga, D., Osborn, T. M., Hasan, M., & Tejidor, L. (2020) · Journal of Intensive Care · doi:10.1186/s40560-020-00446-3 · Cited by 95 · see citing works

Incorporation of dynamic segmented neutrophil-to-monocyte ratio with leukocyte count for sepsis risk stratification

Fang, W., Chen, Y., Wang, Y.-H., Huang, C.-H., Hung, K.-Y., Fang, Y.-T., Chang, Y.-C., Lin, C.-Y., Chang, Y., Chen, H., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-56368-0 · Cited by 91 · see citing works

Management of Urosepsis in 2018

Bonkat, G., Cai, T., Veeratterapillay, R., Bruyère, F., Bartoletti, R., Pilatz, A. M. E., Köves, B., Geerlings, S. E., Pradère, B., Pickard, R. S., et al. (2018) · European Urology Focus · doi:10.1016/j.euf.2018.11.003 · Cited by 89 · see citing works

Risk Factors, Etiologies, and Screening Tools for Sepsis in Pregnant Women: A Multicenter Case-Control Study

Bauer, M. E., Housey, M., Bauer, S. T., Behrmann, S., Chau, A., Clancy, C., Clark, E. A. S., Einav, S., Langen, E., Leffert, L., et al. (2019) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000003709 · Cited by 89 · see citing works

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J‐SSCG 2020)

Egi, M., Ogura, H., Yatabe, T., Atagi, K., Inoue, S., Iba, T., Kakihana, Y., Kawasaki, T., Kushimoto, S., Kuroda, Y., et al. (2021) · Acute Medicine & Surgery · doi:10.1002/ams2.659 · Cited by 86 · see citing works

Surviving Sepsis campaign: international guidelines for Management of Sepsis and Septic Shock 2026

Prescott, H. C., Antonelli, M., Alhazzani, W., Møller, M. H., Alshamsi, F., Azevedo, L. C. P., Belley-Cote, E., De Waele, J., Derde, L., Dionne, J. C., et al. (2026) · Critical Care Medicine · doi:10.1097/ccm.0000000000007075 · Cited by 117 · see citing works

Society for Maternal-Fetal Medicine Consult Series #67: Maternal sepsis

Shields, A. D., Plante, L. A., Pacheco, L. D., & Louis, J. M. (2023) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2023.05.019 · Cited by 79 · see citing works

Comparison of SOFA Score, SIRS, qSOFA, and qSOFA + L Criteria in the Diagnosis and Prognosis of Sepsis

Toker, A. K., Köse, Ş., & Türken, M. (2021) · Eurasian Journal of Medicine · doi:10.5152/eurasianjmed.2021.20081 · Cited by 68 · see citing works

Implementation of a whole of hospital sepsis clinical pathway in a cancer hospital: impact on sepsis management, outcomes and costs

Thursky, K., Lingaratnam, S. M., Jayarajan, J., Haeusler, G. M., Teh, B. W., Tew, M., Venn, G., Hiong, A., Brown, C., Leung, V. K. Y., et al. (2018) · BMJ Open Quality · doi:10.1136/bmjoq-2018-000355 · Cited by 66 · see citing works

Machine learning algorithms for early sepsis detection in the emergency department: a retrospective study

Kijpaisalratana, N., Sanglertsinlapachai, D., Techaratsami, S., Musikatavorn, K., & Saoraya, J. (2022) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2022.104689 · Cited by 65 · see citing works

Comparison of qSOFA score, SOFA score, and SIRS criteria for the prediction of infection and mortality among surgical intermediate and intensive care patients

Koch, C., Edinger, F., Fischer, T., Brenck, F., Hecker, A., Katzer, C., Markmann, M., Sander, M., & Schneck, E. (2020) · World Journal of Emergency Surgery · doi:10.1186/s13017-020-00343-y · Cited by 62 · see citing works

A comparison of different scores for diagnosis and mortality prediction of adults with sepsis in Low-and-Middle-Income Countries: a systematic review and meta-analysis

Adégbitè, B. R., Edoa, J. R., Ndoumba, W. N., Mbadinga, L. B. D., Mombo‐Ngoma, G., Jacob, S. T., Rylance, J., Hänscheid, T., Adégnika, A. A., & Grobusch, M. P. (2021) · EClinicalMedicine · doi:10.1016/j.eclinm.2021.101184 · Cited by 59 · see citing works

Epidemiology of Quick Sequential Organ Failure Assessment Criteria in Undifferentiated Patients and Association With Suspected Infection and Sepsis

Anand, V., Zhang, Z., Kadri, S. S., Klompas, M., & Rhee, C. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.03.032 · Cited by 57 · see citing works

Accuracy of Quick Sequential Organ Failure Assessment Score to Predict Sepsis Mortality in 121 Studies Including 1,716,017 Individuals: A Systematic Review and Meta-Analysis

Herwanto, V., Shetty, A., Nalos, M., Chakraborty, M., McLean, A., Eslick, G. D., & Tang, B. (2019) · Critical Care Explorations · doi:10.1097/cce.0000000000000043 · Cited by 58 · see citing works

Development and validation of a score to predict mortality in ICU patients with sepsis: a multicenter retrospective study

Weng, J., Hou, R., Zhou, X., Xu, Z., Zhou, Z., Wang, P., Wang, L., Chen, C., Wu, J., & Wang, Z. (2021) · Journal of Translational Medicine · doi:10.1186/s12967-021-03005-y · Cited by 53 · see citing works

Management of Sepsis and Septic Shock: What Have We Learned in the Last Two Decades?

Kamath, S., Altaq, H. H., & Abdo, T. (2023) · Microorganisms · doi:10.3390/microorganisms11092231 · Cited by 53 · see citing works

New guidelines for severe community-acquired pneumonia

Martín‐Loeches, I., & Torres, A. (2021) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000760 · Cited by 48 · see citing works

Quick Sequential Organ Failure Assessment as a prognostic factor for infected patients outside the intensive care unit: a systematic review and meta-analysis

Liu, Y., Luo, Y., Zhang, X., Shou, S., Gao, Y., Bin, L., Li, C., & Chai, Y. (2019) · Internal and Emergency Medicine · doi:10.1007/s11739-019-02036-0 · Cited by 46 · see citing works

The SIRS criteria have better performance for predicting infection than qSOFA scores in the emergency department

Gando, S., Shiraishi, A., Abe, T., Kushimoto, S., Mayumi, T., Fujishima, S., Hagiwara, A., Shiino, Y., Shiraishi, S., Hifumi, T., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-64314-8 · Cited by 48 · see citing works

Endothelial dysfunction is an early indicator of sepsis and neutrophil degranulation of septic shock in surgical patients

Martín-Fernández, M., Roncero, L. M. V., Almansa, R., Gómez-Sánchez, E., Martín, S., Tamayo, E., Esteban-Velasco, M. C., RUIZ-GRANADO, P., Aragón, M. F., Calvo, D., et al. (2020) · BJS Open · doi:10.1002/bjs5.50265 · Cited by 43 · see citing works

qSOFA score for prediction of sepsis outcome in emergency department

Shahsavarinia, K., Moharramzadeh, P., Arvanagi, R. J., & Mahmoodpoor, A. (2020) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.36.4.2031 · Cited by 40 · see citing works

Challenging the One-hour Sepsis Bundle

Kalantari, A., & Rezaie, S. R. (2019) · Western Journal of Emergency Medicine · doi:10.5811/westjem.2018.11.39290 · Cited by 37 · see citing works

Association between site of infection and in-hospital mortality in patients with sepsis admitted to emergency departments of tertiary hospitals in Medellin, Colombia

Caraballo, C., Ascuntar, J., Hincapié, C., Restrepo, C., Bernal, E., & Jaimes, F. A. (2019) · Revista Brasileira de Terapia Intensiva · doi:10.5935/0103-507x.20190011 · Cited by 36 · see citing works

Preoperative Midstream Urine Cultures vs Renal Pelvic Urine Culture or Stone Culture in Predicting Systemic Inflammatory Response Syndrome and Urosepsis After Percutaneous Nephrolithotomy: A Systematic Review and Meta-Analysis

Liu, M., Chen, J., Gao, M. Q., Zeng, H., Cui, Y., Zhu, Z., & Chen, H. (2021) · Journal of Endourology · doi:10.1089/end.2020.1140 · Cited by 36 · see citing works

Dynamic Prediction of Patient Outcomes in the Intensive Care Unit: A Scoping Review of the State-of-the-Art

Lapp, L., Roper, M., Kavanagh, K., Bouamrane, M.-M., & Schraag, S. (2023) · Journal of Intensive Care Medicine · doi:10.1177/08850666231166349 · Cited by 36 · see citing works

Early Physician Gestalt Versus Usual Screening Tools for the Prediction of Sepsis in Critically Ill Emergency Patients

Knack, S. K., Scott, N. L., Driver, B. E., Prekker, M. E., Black, L. P., Hopson, C., Maruggi, E., Kaus, O., Tordsen, W. J., & Puskarich, M. A. (2024) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2024.02.009 · Cited by 35 · see citing works

SIRS or qSOFA? Is that the question? Clinical and methodological observations from a meta-analysis and critical review on the prognostication of patients with suspected sepsis outside the ICU

Franchini, S., Scarallo, L., Carlucci, M., Cabrini, L., & Tresoldi, M. (2018) · Internal and Emergency Medicine · doi:10.1007/s11739-018-1965-0 · Cited by 34 · see citing works

Application Prospect of the SOFA Score and Related Modification Research Progress in Sepsis

Wang, X., Guo, Z., Chai, Y., Wang, Z., Liao, H., Wang, Z., & Wang, Z. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12103493 · Cited by 37 · see citing works

Accuracy of qSOFA for the diagnosis of sepsis-3: a secondary analysis of a population-based cohort study

Tian, H., Zhou, J., Weng, L., Hu, X. X., Peng, J., Wang, C.-Y., Jiang, W., Du, X., Xi, X., An, Y., et al. (2019) · Journal of Thoracic Disease · doi:10.21037/jtd.2019.04.90 · Cited by 30 · see citing works

Structured, proactive care coordination versus usual care for Improving Morbidity during Post-Acute Care Transitions for Sepsis (IMPACTS): a pragmatic, randomized controlled trial

On behalf of Atrium Health ACORN Investigators, Kowalkowski, M., Chou, S.-H., McWilliams, A., Lashley, C., Murphy, S., Rossman, W., Papali, A., Heffner, A., Russo, M., et al. (2019) · Trials · doi:10.1186/s13063-019-3792-7 · Cited by 29 · see citing works

What is new and different in the 2021 Surviving Sepsis Campaign guidelines

Prescott, H. C., & Ostermann, M. (2023) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-023-01028-5 · Cited by 32 · see citing works

The Impact of Sepsis on the Outcomes of COPD Patients: A Population-Based Cohort Study

Chen, C., Lai, C., Wang, Y., Wang, C., Wang, H., Yu, C., & Chen, L. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7110393 · Cited by 29 · see citing works

Development and Validation of a Quick Sepsis-Related Organ Failure Assessment-Based Machine-Learning Model for Mortality Prediction in Patients with Suspected Infection in the Emergency Department

Kwon, Y. S., & Baek, M. S. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9030875 · Cited by 29 · see citing works

Quick Sequential Organ Failure Assessment Score and the Modified Early Warning Score for Predicting Clinical Deterioration in General Ward Patients Regardless of Suspected Infection

Ko, R., Kwon, O., Cho, K.-J., Lee, Y. J., Kwon, J., Park, J., Kim, J. S., Kim, A. J., Jo, Y. H., Lee, Y., et al. (2022) · Journal of Korean Medical Science · doi:10.3346/jkms.2022.37.e122 · Cited by 29 · see citing works

Biomarkers of sepsis in pigs, horses and cattle: from acute phase proteins to procalcitonin

López-Martínez, M. J., Franco‐Martínez, L., Martı́nez-Subiela, S., & Cerón, J. M. C. (2022) · Animal Health Research Reviews · doi:10.1017/s1466252322000019 · Cited by 29 · see citing works

Comparison of Sepsis Definitions as Automated Criteria

Yu, S. C., Betthauser, K. D., Gupta, A., Lyons, P. G., Lai, A. M., Kollef, M. H., Payne, P. R. O., & Michelson, A. P. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000004875 · Cited by 29 · see citing works

Prognostic ability of quick-SOFA across different age groups of patients with suspected infection outside the intensive care unit: A cohort study

Ramos, J. G. R., Passos, R. D. H., Teixeira, M. B., Gobatto, A. L. N., Coutinho, R. V. D. S., Caldas, J. R., da Guarda, S. N. F., Ribeiro, M. P., & Batista, P. B. P. (2018) · Journal of Critical Care · doi:10.1016/j.jcrc.2018.07.008 · Cited by 27 · see citing works

Diagnostic and Prognostic Utility Compared Among Different Sepsis Scoring Systems in Adult Patients With Sepsis in Thailand: A Prospective Cohort Study

Pairattanakorn, P., Angkasekwinai, N., Sirijatuphat, R., Wangchinda, W., Tancharoen, L., & Thamlikitkul, V. (2020) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofaa573 · Cited by 27 · see citing works

A Prospective Comparison of Quick Sequential Organ Failure Assessment, Systemic Inflammatory Response Syndrome Criteria, Universal Vital Assessment, and Modified Early Warning Score to Predict Mortality in Patients with Suspected Infection in Gabon

Schmedding, M., Adégbitè, B. R., Gould, S., Beyeme, J. O., Adégnika, A. A., Grobusch, M. P., & Huson, M. A. M. (2018) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.18-0577 · Cited by 25 · see citing works

Improving clinical outcomes in sepsis and multiple organ dysfunction through precision medicine

Mehta, S., & Gill, S. E. (2019) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.11.74 · Cited by 26 · see citing works

Developing a shared sepsis data infrastructure: a systematic review and concept map to FHIR

Brant, E. B., Kennedy, J. N., King, A. J., Gerstley, L. D., Mishra, P., Schlessinger, D., Shalaby, J., Escobar, G. J., Angus, D. C., Seymour, C. W., et al. (2022) · npj Digital Medicine · doi:10.1038/s41746-022-00580-2 · Cited by 24 · see citing works

Early Diagnosis of Sepsis: The Role of Biomarkers and Rapid Microbiological Tests

Plata-Menchaca, E. P., Ruiz‐Rodríguez, J. C., & Ferrer, R. (2024) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0044-1787270 · Cited by 25 · see citing works

Monocyte distribution width as part of a broad pragmatic sepsis screen in the emergency department

Malinovska, A., Hinson, J. S., Badaki‐Makun, O., Hernried, B., Smith, A., Debraine, A., Toerper, M. F., Rothman, R. E., Kickler, T. S., & Levin, S. (2022) · Journal of the American College of Emergency Physicians Open · doi:10.1002/emp2.12679 · Cited by 24 · see citing works

Update in Infectious Diseases 2018.

Candel, F. J., Emilov, T., de la Torre, I. D., Ruedas, A., Viñuela-Prieto, J. M., Visiedo, C., Martínez-Jordán, J., López-González, L., Matesanz, M., & Arribi, A. (2018) · Europe PMC (PubMed Central) · Cited by 23 · see citing works

Added value of inflammatory markers to vital signs to predict mortality in patients suspected of severe infection

Takada, T., Hoogland, J., Yano, T., Fujii, K., Fujiishi, R., Miyashita, J., Takeshima, T., Hayashi, M., Azuma, T., & Moons, K. G. M. (2019) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2019.11.030 · Cited by 23 · see citing works

Computer-aided National Early Warning Score to predict the risk of sepsis following emergency medical admission to hospital: a model development and external validation study

Faisal, M., Richardson, D., Scally, A., Howes, R., Beatson, K., Speed, K., & Mohammed, M. A. (2019) · Canadian Medical Association Journal · doi:10.1503/cmaj.181418 · Cited by 22 · see citing works

MR‐ proADM to detect specific types of organ failure in infection

Andrés, C., Andaluz‐Ojeda, D., Cicuéndez, R., Nogales, L., Martín, S., Martín-Fernández, M., Almansa, R., Calvo, D., Esteban-Velasco, M. C., Roncero, L. M. V., et al. (2020) · European Journal of Clinical Investigation · doi:10.1111/eci.13246 · Cited by 22 · see citing works

A generalizable and interpretable model for mortality risk stratification of sepsis patients in intensive care unit

Zhuang, J., Huang, H., Jiang, S., Liang, J., Liu, Y., & Yu, X. (2023) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-023-02279-0 · Cited by 24 · see citing works

Role of qSOFA and SOFA Scoring Systems for Predicting In-Hospital Risk of Deterioration in the Emergency Department

López‐Izquierdo, R., Ibáñez, P., Rodríguez, F. M., Mohedano‐Moriano, A., López, B. P., Maestre-Miquel, C., Viñuela, A., Durantez‐Fernández, C., Villamor, M. Á. C., & Martín‐Conty, J. L. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17228367 · Cited by 21 · see citing works

Combining quick sequential organ failure assessment score with heart rate variability may improve predictive ability for mortality in septic patients at the emergency department

Prabhakar, S. M., Tagami, T., Liu, N., Samsudin, M. I., Ng, J. C. J., Koh, Z. X., & Ong, M. E. H. (2019) · PLoS ONE · doi:10.1371/journal.pone.0213445 · Cited by 21 · see citing works

A prospective validation of Sepsis-3 guidelines in acute hepatobiliary sepsis: qSOFA lacks sensitivity and SIRS criteria lacks specificity (Cohort Study)

Mak, M. H. W., Low, J. K., Junnarkar, S. P., Huey, T. C. W., & Shelat, V. G. (2019) · International Journal of Surgery · doi:10.1016/j.ijsu.2019.10.022 · Cited by 21 · see citing works

Public health programmes for vitamin A deficiency control

Bruins, M. J., & Kraemer, K. (2013) · Community Eye Health Journal · doi:10.56920/cehj.681 · Cited by 20 · see citing works

The Integration of qSOFA with Clinical Variables and Serum Biomarkers Improves the Prognostic Value of qSOFA Alone in Patients with Suspected or Confirmed Sepsis at ED Admission

Mearelli, F., Barbati, G., Casarsa, C., Giansante, C., Breglia, A., Spica, A., Moras, C., Olivieri, G., Occhipinti, A. A., Nardo, M. D., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9041205 · Cited by 21 · see citing works

Predictive value of SOFA, PCT, Lactate, qSOFA and their combinations for mortality in patients with sepsis: A systematic review and meta-analysis

Lu, J., Dong, Z., Ye, L., Gao, Y., & Zheng, Z. (2025) · PLoS ONE · doi:10.1371/journal.pone.0332525 · Cited by 20 · see citing works

Effect of do-not-resuscitate orders on patients with sepsis in the medical intensive care unit: a retrospective, observational and propensity score-matched study in a tertiary referral hospital in Taiwan

Chang, Y.-C., Fang, Y.-T., Chen, H., Lin, C.-Y., Chang, Y.-P., Chen, Y., Huang, C.-H., Huang, K., Chang, H., Su, M., et al. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-029041 · Cited by 21 · see citing works

Back to Basics: Recognition of Sepsis with New Definition

Horák, J., Martínková, V., Raděj, J., & Matějovič, M. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8111838 · Cited by 20 · see citing works

Prospective evaluation of the quickSOFA score as a screening for sepsis in the emergency department

Loritz, M., Busch, H.-J., Helbing, T., & Fink, K. (2020) · Internal and Emergency Medicine · doi:10.1007/s11739-019-02258-2 · Cited by 20 · see citing works

Nomograms for Predicting the Risk of SIRS and Urosepsis after Uroscopic Minimally Invasive Lithotripsy

Wang, C., Xu, R., Zhang, Y., Wu, Y., Zhang, T., Dong, X., Zhang, R., & Hu, X. (2022) · BioMed Research International · doi:10.1155/2022/6808239 · Cited by 19 · see citing works

The systemic inflammatory response syndrome criteria and their differential association with mortality

Kaukonen, K.-M., Bailey, M., Pilcher, D. V., Cooper, D. J., & Bellomo, R. (2018) · Journal of Critical Care · doi:10.1016/j.jcrc.2018.04.005 · Cited by 18 · see citing works

[Comparison of four scoring systems for predicting ICU mortality in patients with sepsis].

Hu, C., Hu, B., Li, Z., Yang, X., Song, H., & Li, J. (2020) · PubMed Central · doi:10.12122/j.issn.1673-4254.2020.04.10 · Cited by 18 · see citing works

Contrasting qSOFA and SIRS Criteria for Early Sepsis Identification in a Veteran Population.

Dykes, L. A., Heintz, S. J., Heintz, B. H., Livorsi, D. J., Egge, J. A., & Lund, B. C. (2019) · Europe PMC (PubMed Central) · Cited by 18 · see citing works

Factors associated with inflamm-aging in institutionalized older people

Neto, L. D. O., Tavares, V. D. D. O., Agrícola, P. M. D., de Oliveira, L. P., Sales, M. C., Sena‐Evangelista, K. C. M., Gomes, I. C., Coelho, N. L. G., Pedrosa, L. F. C., & de Lima, K. C. (2021) · Scientific Reports · doi:10.1038/s41598-021-97225-3 · Cited by 17 · see citing works

Prognostic performance of endothelial biomarkers to early predict clinical deterioration of patients with suspected bacterial infection and sepsis admitted to the emergency department

Lafon, T., Cazalis, M.-A., Vallejo, C., Tazarourte, K., Blein, S., Pachot, A., Laterre, P., Laribi, S., François, B., Textoris, J., et al. (2020) · Annals of Intensive Care · doi:10.1186/s13613-020-00729-w · Cited by 17 · see citing works

Recommendations for antibiotic selection for severe nosocomial infections

Mensa, J., Barberán, J., Ferrer, R., Borges-Sa, M., Sedes, P. R., Maseda, E., Oliver, A., Marco, F., Adàlia, R., Aguilar, G., et al. (2021) · Revista Española de Quimioterapia · doi:10.37201/req/126.2021 · Cited by 16 · see citing works

Antibiotic treatment in patients with sepsis: a narrative review

Plata-Menchaca, E. P., Ferrer, R., Ruiz‐Rodríguez, J. C., Morais, R., & Póvoa, P. M. S. R. (2020) · Hospital Practice · doi:10.1080/21548331.2020.1791541 · Cited by 17 · see citing works

Nanotechnology Applications in Sepsis: Essential Knowledge for Clinicians

Vasconcelos, I., & Santos, T. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15061682 · Cited by 19 · see citing works

Consideration of Occult Infection and Sepsis Mimics in the Sick Patient Without an Apparent Infectious Source

Boushra, M. N., Miller, S. N., Koyfman, A., & Long, B. (2018) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2018.09.035 · Cited by 14 · see citing works

Application of dynamic pulse pressure and vasopressor tools for predicting outcomes in patients with sepsis in intensive care units

Fang, W., Huang, C.-H., Chen, Y., Hung, K.-Y., Chang, Y.-C., Lin, C.-Y., Fang, Y.-T., Chang, Y., Chen, H., Huang, K., et al. (2019) · Journal of Critical Care · doi:10.1016/j.jcrc.2019.05.003 · Cited by 13 · see citing works

Prognostic accuracy of SIRS criteria and qSOFA score for in-hospital mortality among influenza patients in the emergency department

Chu, S., Seak, C., Su, T., Chaou, C., Tseng, H., & Li, C.-H. (2020) · BMC Infectious Diseases · doi:10.1186/s12879-020-05102-7 · Cited by 14 · see citing works

Identification and Validation of an Explainable Prediction Model of Sepsis in Patients With Intracerebral Hemorrhage: Multicenter Retrospective Study

Liu, X., Huang, Z., Guo, Y., Li, Y., Zhu, J., Wen, J., Gao, Y., & Liu, J. (2025) · Journal of Medical Internet Research · doi:10.2196/71413 · Cited by 13 · see citing works

Validation of National Early Warning Score and Quick Sequential ( sepsis‐related ) Organ Failure Assessment in acute myeloid leukaemia patients treated with intensive chemotherapy

Frairia, C., Nicolino, B., Secreto, C., Messa, E., Arrigo, G., Busca, A., Cerrano, M., D’Ardìa, S., Dellacasa, C. M., Evangelista, A., et al. (2023) · European Journal Of Haematology · doi:10.1111/ejh.13952 · Cited by 13 · see citing works

Classification versus Prediction of Mortality Risk using the SIRS and qSOFA Scores in Patients with Infection Transported by Paramedics

Lane, D. J., Lin, S., & Scales, D. C. (2019) · Prehospital Emergency Care · doi:10.1080/10903127.2019.1624901 · Cited by 13 · see citing works

Electronic early notification of sepsis in hospitalized ward patients: a study protocol for a stepped-wedge cluster randomized controlled trial

Arabi, Y. M., Alsaawi, A., Zahrani, M., Khathaami, A. M. A., AlHazme, R. H., Mutrafy, A. A., Qarni, A. A. A., Shouabi, A. A., Qasim, E. A., Abdukahil, S. A., et al. (2021) · Trials · doi:10.1186/s13063-021-05562-5 · Cited by 13 · see citing works

Quick Sequential Organ Failure Assessment Is Not Good for Ruling Sepsis In or Out

Kalil, A. C., & Machado, F. R. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.06.003 · Cited by 13 · see citing works

Validation of Sepsis-3 using survival analysis and clinical evaluation of quick SOFA, SIRS, and burn-specific SIRS for sepsis in burn patients with suspected infection

Yoon, J., Kym, D., Hur, J., Cho, Y. S., Chun, W., & Yoon, D. (2023) · PLoS ONE · doi:10.1371/journal.pone.0276597 · Cited by 12 · see citing works

The prognostic utility of prehospital qSOFA in addition to emergency department qSOFA for sepsis in patients with suspected infection: A retrospective cohort study

Saito, A., Osawa, I., Shibata, J., Sonoo, T., Nakamura, K., & Goto, T. (2023) · PLoS ONE · doi:10.1371/journal.pone.0282148 · Cited by 12 · see citing works

Identification of Risk Factors and Prediction of Sepsis in Pregnancy Using Machine Learning Methods

Kopanitsa, G., Metsker, O., Paskoshev, D. D., & Greschischeva, S. (2021) · Procedia Computer Science · doi:10.1016/j.procs.2021.10.040 · Cited by 12 · see citing works

Prognostic value of the Quick Sepsis-related Organ Failure Assessment (qSOFA) score among critically ill medical and surgical patients with suspected infection in a resourcelimited setting

Bischop, L. A., Wilson, D., Wise, R., Savarimuthu, S. M., & Anesi, G. L. (2021) · African Journal of Thoracic and Critical Care Medicine · doi:10.7196/ajtccm.2021.v27i4.158 · Cited by 12 · see citing works

Predictive accuracy of Sepsis-3 definitions for mortality among adult critically ill patients with suspected infection

Chen, Q., Shao, J., Liu, W., Wang, H., Liu, L., Gu, X., & Zheng, R. (2019) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000166 · Cited by 12 · see citing works

50 Years of Sepsis Investigation/Enlightenment Among Adults—The Long and Winding Road

Dellinger, R. P., Levy, M. M., Schorr, C., & Townsend, S. R. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005203 · Cited by 12 · see citing works

Challenges in early detection and prognostication of sepsis: new approaches from the emergency department and intensive care unit

Lafon, T., Weingart, M., Vaidie, J., Calfee, C. S., Jacob, S. T., Freund, Y., Shapiro, N. I., Barraud, O., Monneret, G., van der Poll, T., et al. (2026) · EClinicalMedicine · doi:10.1016/j.eclinm.2026.103864 · Cited by 13 · see citing works

Dynamic analysis of acute deterioration in chronic liver disease patients using modified quick sequential organ failure assessment

Song, D. S., Kim, H. Y., Jung, Y. K., Kim, T. H., Yim, H. J., Yoon, E. L., Suk, K. T., Yoo, J., Kim, S. G., Kim, M. Y., et al. (2024) · Clinical and Molecular Hepatology · doi:10.3350/cmh.2023.0563 · Cited by 11 · see citing works

Preventing, identifying, and managing sepsis in the community: research and clinical priorities

Rudd, K. E., Randolph, A. G., Angus, D. C., Bauer, M. W., Chesley, C. F., Filbin, M. R., Jenq, G. Y., Kempker, J. A., Levine, A. C., Levy, P. D., et al. (2025) · The Lancet Primary Care · doi:10.1016/j.lanprc.2025.100010 · Cited by 11 · see citing works

Impact of a qSOFA-based triage procedure on antibiotic timing in ED patients with sepsis: A prospective interventional study

Petit, J., Passerieux, J., Maître, O., Guérin, C., Rozelle, C., Cordeau, O., Cassonnet, A., Malet, A., Boulain, T., Barbier, F., et al. (2019) · The American Journal of Emergency Medicine · doi:10.1016/j.ajem.2019.05.022 · Cited by 11 · see citing works

Improving the diagnosis and prognosis of sepsis according to the sources of infection

Mendoza, D., Ascuntar, J., Rosero, O., & Jaimes, F. A. (2022) · Emergency Medicine Journal · doi:10.1136/emermed-2021-211910 · Cited by 11 · see citing works

Monocyte Distribution Width as a predictor of community acquired sepsis in patients prospectively enrolled at the Emergency Department

Polilli, E., Iorio, G. D., Silveri, C., Angelini, G., Anelli, M. C., Esposito, J. E., D’Amato, M., Parruti, G., & Carinci, F. (2022) · BMC Infectious Diseases · doi:10.1186/s12879-022-07803-7 · Cited by 11 · see citing works

Early Identification of Sepsis-Induced Acute Kidney Injury by Using Monocyte Distribution Width, Red-Blood-Cell Distribution, and Neutrophil-to-Lymphocyte Ratio

Pan, Y.-H., Tsai, H., Lin, H.-A., Chen, C., Chao, C.-C., Lin, S., & Hou, S. (2024) · Diagnostics · doi:10.3390/diagnostics14090918 · Cited by 13 · see citing works

Maternal sepsis: new concepts, new practices

Foeller, M. E., & Gibbs, R. S. (2019) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000523 · Cited by 11 · see citing works

Performance of scores in the prediction of clinical outcomes in patients admitted from the emergency service

da Silva, L. M. F., Diogo, L. P., Vieira, L. B., Michielin, F. D. C., Santarém, M. D., & Machado, M. L. P. (2021) · Revista Latino-Americana de Enfermagem · doi:10.1590/1518-8345.4722.3479 · Cited by 11 · see citing works

Patients with Bacterial Sepsis Are Heterogeneous with Regard to Their Systemic Lipidomic Profiles

Mosevoll, K. A., Hansen, B., Gundersen, I. M., Reikvam, H., Bruserud, Ø., Bruserud, Ø., & Bruserud, Ø. (2022) · Metabolites · doi:10.3390/metabo13010052 · Cited by 11 · see citing works

Are qSOFA Criteria Better Than the Systemic Inflammatory Response Syndrome Criteria for Diagnosing Sepsis and Predicting Inhospital Mortality?

Long, B., & April, M. D. (2018) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2018.03.008 · Cited by 7 · see citing works

Combination of Systemic Inflammatory Response Syndrome and Quick-SOFA

Xu, R. (2019) · CHEST Journal · doi:10.1016/j.chest.2018.09.033 · Cited by 1 · see citing works

Which rating system is better – qSOFA or SIRS?

Peneva, P., Nikolova, S., & Bocheva, Y. (2019) · Scripta Scientifica Medica · doi:10.14748/ssm.v51i3.6407 · Cited by 1 · see citing works

Comparison of QSOFA score and SIRS criteria for prediction of sepsis outcome of patients with suspicion of sepsis outside the intensive care unit: A single-center retrospective studyPreprint

Mosavi, M., & Mahfoozi, L. (2021) · Research Square · doi:10.21203/rs.3.rs-286120/v1

SIRS or qSOFA? Is that the question? Clinical and methodological observations from a meta-analysis and critical review on the prognostication of patients with suspected sepsis outside the ICU

Franchini, S., Scarallo, L., Carlucci, M., Cabrini, L., & Tresoldi, M. (2018) · Internal and Emergency Medicine · doi:10.1007/s11739-018-1965-0 · Cited by 34 · see citing works