Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Huang, D. W., Sherman, B. T., & Lempicki, R. A. (2009) · Nature Protocols · doi:10.1038/nprot.2008.211 · Cited by 35,890 · see citing works

QIIME allows analysis of high-throughput community sequencing data

Caporaso, J. G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F. D., Costello, E. K., Fierer, N., Peña, A. G., Goodrich, J. K., Gordon, J. I., et al. (2010) · Nature Methods · doi:10.1038/nmeth.f.303 · Cited by 34,887 · see citing works

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions.

Kim, D., Pertea, G., Trapnell, C., Pimentel, H., Kelley, R., & Salzberg, S. L. (2013) · Genome Biology · doi:10.1186/gb-2013-14-4-r36 · Cited by 12,668 · see citing works

The microbiome and innate immunity

Thaiss, C. A., Zmora, N., Levy, M., & Elinav, E. (2016) · Nature · doi:10.1038/nature18847 · Cited by 2,012 · see citing works

Detecting differential usage of exons from RNA-seq data

Anders, S., Reyes, A., & Huber, W. (2012) · Genome Research · doi:10.1101/gr.133744.111 · Cited by 1,545 · see citing works

Minireview: Gut microbiota: The neglected endocrine organ

Clarke, G., Stilling, R. M., Kennedy, P. J., Stanton, C., Cryan, J. F., & Dinan, T. G. (2014) · Molecular Endocrinology · doi:10.1210/me.2014-1108 · Cited by 1,192 · see citing works

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

Ryu, J.-H., Kim, S.-H., Lee, H.-Y., Bai, J. Y., Nam, Y., Bae, J., Lee, D. G., Shin, S. C., Ha, E.-M., & Lee, W. (2008) · Science · doi:10.1126/science.1149357 · Cited by 832 · see citing works

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

Wang, J., Thingholm, L. B., Skiecevičienė, J., Rausch, P., Kummen, M., Hov, J. R., Degenhardt, F., Heinsen, F.-A., Rühlemann, M. C., Szymczak, S., et al. (2016) · Nature Genetics · doi:10.1038/ng.3695 · Cited by 625 · see citing works

Requirement for a Peptidoglycan Recognition Protein (PGRP) in Relish Activation and Antibacterial Immune Responses in Drosophila

Choe, K., Werner, T., Stöven, S., Hultmark, D., & Anderson, K. V. (2002) · Science · doi:10.1126/science.1070216 · Cited by 606 · see citing works

COURTSHIP IN DROSOPHILA

Greenspan, R. J., & Ferveur, J. (2000) · Annual Review of Genetics · doi:10.1146/annurev.genet.34.1.205 · Cited by 594 · see citing works

Gut-associated microbes of Drosophila melanogaster

Broderick, N. A., & Lemaître, B. (2012) · Gut Microbes · doi:10.4161/gmic.19896 · Cited by 555 · see citing works

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

Clark, R. I., Salazar, A., Yamada, R., Fitz-Gibbon, S., Morselli, M., Alcaraz, J., Rana, A., Rera, M., Pellegrini, M., Ja, W. W., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.08.004 · Cited by 510 · see citing works

Gut homeostasis in a microbial world: insights from Drosophila melanogaster

Buchon, N. S., Broderick, N. A., & Lemaître, B. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3074 · Cited by 493 · see citing works

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

Broderick, N. A., Buchon, N., & Lemaître, B. (2014) · mBio · doi:10.1128/mbio.01117-14 · Cited by 431 · see citing works

Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes

Chen, K., Chen, Z., Wu, D., Zhang, L., Lin, X., Su, J., Rodriguez, B., Xi, Y., Xia, Z., Chen, X., et al. (2015) · Nature Genetics · doi:10.1038/ng.3385 · Cited by 373 · see citing works

FOXO-dependent regulation of innate immune homeostasis

Becker, T., Loch, G., Beyer, M., Zinke, I., Aschenbrenner, A. C., Carrera, P., Inhester, T., Schultze, J. L., & Hoch, M. (2010) · Nature · doi:10.1038/nature08698 · Cited by 357 · see citing works

Gut microbiota dictates the metabolic response ofDrosophilato diet

Wong, A. C.-N., Dobson, A. J., & Douglas, A. E. (2014) · Journal of Experimental Biology · doi:10.1242/jeb.101725 · Cited by 305 · see citing works

Altered brain-gut axis in autism: comorbidity or causative mechanisms

Mayer, E. A., Padua, D., & Tillisch, K. (2014) · BioEssays · doi:10.1002/bies.201400075 · Cited by 304 · see citing works

The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growthPreprint

Secombe, J., Li, L., Carlos, L. S., & Eisenman, R. N. (2007) · Genes & Development · doi:10.1101/gad.1523007 · Cited by 277 · see citing works

Peptidoglycan Sensing by the Receptor PGRP-LE in the Drosophila Gut Induces Immune Responses to Infectious Bacteria and Tolerance to Microbiota

Bosco-Drayon, V., Poidevin, M., Boneca, I. G., Narbonne-Reveau, K., Royet, J., & Charroux, B. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.06.002 · Cited by 255 · see citing works

Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila

Wu, S.-C., Cao, Z.-S., Chang, K.-M., & Juang, J. (2017) · Nature Communications · doi:10.1038/s41467-017-00040-6 · Cited by 253 · see citing works

NF- B in the Immune Response of DrosophilaPreprint

Hétru, C., & Hoffmann, J. A. (2009) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000232 · Cited by 252 · see citing works

Cognitive decline, dietary factors and gut–brain interactions

Caracciolo, B., Xu, W., Collins, S. M., & Fratiglioni, L. (2013) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2013.11.011 · Cited by 205 · see citing works

Redox signaling mediated by the gut microbiota

Jones, R. M., & Neish, A. S. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.10.495 · Cited by 204 · see citing works

Quantifying the contribution of recessive coding variation to developmental disorders

Martin, H. C., Jones, W. D., McIntyre, R., Sanchez-Andrade, G., Sanderson, M., Stephenson, J. D., Jones, C. P., Handsaker, J., Gallone, G., Bruntraeger, M., et al. (2018) · Science · doi:10.1126/science.aar6731 · Cited by 201 · see citing works

Ecdysone triggered PGRP‐LC expression controls Drosophila innate immunity

Rus, F., Flatt, T., Tong, M., Aggarwal, K., Okuda, K., Kleino, A., Yates, E., Tatar, M., & Silverman, N. S. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.100 · Cited by 174 · see citing works

Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction

Bross, T. G., Rogina, B., & Helfand, S. L. (2005) · Aging Cell · doi:10.1111/j.1474-9726.2005.00181.x · Cited by 166 · see citing works

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder

Koemans, T. S., Kleefstra, T., Chubak, M. C., Stone, M. H., Reijnders, M. R. F., de Munnik, S., Willemsen, M. H., Fencková, M., Schrander-Stumpel, C. T. R. M., Bok, L. A., et al. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006864 · Cited by 159 · see citing works

Speciation by Symbiosis: the Microbiome and Behavior

Shropshire, J. D., & Bordenstein, S. R. (2016) · mBio · doi:10.1128/mbio.01785-15 · Cited by 152 · see citing works

Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes

Tynkkynen, S. (1998) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(98)00051-8 · Cited by 149 · see citing works

Coordination of legs during straight walking and turning in Drosophila melanogaster

Strau�, R., & Heisenberg, M. (1990) · Journal of Comparative Physiology A · doi:10.1007/bf00192575 · Cited by 146 · see citing works

Nutrient-Dependent Impact of Microbes onDrosophila suzukiiDevelopment

Bing, X., Gerlach, J., Loeb, G. M., & Buchon, N. S. (2018) · mBio · doi:10.1128/mbio.02199-17 · Cited by 142 · see citing works

A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone Methylation

Iwase, S., Brookes, E., Agarwal, S., Badeaux, A. I., Ito, H., Vallianatos, C. N., Tomassy, G. S., Kasza, T., Lin, G. R., Thompson, A., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2015.12.091 · Cited by 132 · see citing works

Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome

Snijders, A. M., Langley, S. A., Kim, Y., Brislawn, C., Noecker, C. A., Zink, E., Fansler, S. J., Casey, C., Miller, D. R., Huang, Y., et al. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.221 · Cited by 131 · see citing works

Loss of Kdm5c Causes Spurious Transcription and Prevents the Fine-Tuning of Activity-Regulated Enhancers in Neurons

Scandaglia, M., López‐Atalaya, J. P., Medrano-Fernandez, A., López-Cascales, M. T., del Blanco, B., Lipiński, M., Benito, E., Olivares, R., Iwase, S., Shi, Y., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.09.014 · Cited by 123 · see citing works

Social attraction mediated by fruit flies' microbiome

Venu, I., Durisko, Z., Xu, J., & Dukas, R. (2014) · Journal of Experimental Biology · doi:10.1242/jeb.099648 · Cited by 114 · see citing works

Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila

Qian, Y., Cao, Y., Deng, B., Yang, G., Li, J., Xu, R., Zhang, D., Huang, J., & Rao, Y. (2017) · eLife · doi:10.7554/elife.26519 · Cited by 104 · see citing works

Binding and Cellular Activation Studies Reveal That Toll-like Receptor 2 Can Differentially Recognize Peptidoglycan from Gram-positive and Gram-negative Bacteria

Asong, J., Wolfert, M. A., Maiti, K. K., Miller, D. K., & Boons, G. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m806633200 · Cited by 103 · see citing works

The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif

Liu, X., & Secombe, J. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.11.007 · Cited by 101 · see citing works

Mutations in the intellectual disability gene KDM5C reduce protein stability and demethylase activity

Brookes, E., Laurent, B., Õunap, K., Carroll, R., Moeschler, J. B., Field, M. J., Schwartz, C. E., Gécz, J., & Shi, Y. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv046 · Cited by 88 · see citing works

Rett Syndrome: A Focus on Gut Microbiota

Borghi, E., Borgo, F., Severgnini, M., Savini, M. N., Casiraghi, M. C., & Vignoli, A. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18020344 · Cited by 88 · see citing works

RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo

Ptaschinski, C., Mukherjee, S., Moore, M. L., Albert, M., Helin, K., Kunkel, S. L., & Lukacs, N. W. (2015) · PLoS Pathogens · doi:10.1371/journal.ppat.1004978 · Cited by 84 · see citing works

Comparative Analysis of Drosophila melanogaster Gut Microbiota with Respect to Host Strain, Sex, and Age

Han, G., Lee, H., Jeong, S. E., Jeon, C. O., & Hyun, S. (2017) · Microbial Ecology · doi:10.1007/s00248-016-0925-3 · Cited by 69 · see citing works

Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling

Navarro‐Costa, P., McCarthy, A., Prudêncio, P., Greer, C., Guilgur, L. G., Becker, J. D., Secombe, J., Rangan, P., & Martinho, R. G. (2016) · Nature Communications · doi:10.1038/ncomms12331 · Cited by 67 · see citing works

Beyond immunity: The Imd pathway as a coordinator of host defense, organismal physiology and behavior

Zhai, Z., Huang, X., & Yin, Y. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.11.008 · Cited by 67 · see citing works

Drosophila as a model for intestinal dysbiosis and chronic inflammatory diseases

Lee, K., & Lee, W. (2013) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2013.05.005 · Cited by 62 · see citing works

The neurogenetics of group behavior inDrosophila melanogaster

Ramdya, P. P., Schneider, J., & Levine, J. D. (2017) · Journal of Experimental Biology · doi:10.1242/jeb.141457 · Cited by 60 · see citing works

KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress

Liu, X., Greer, C., & Secombe, J. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004676 · Cited by 57 · see citing works

Leveraging blood serotonin as an endophenotype to identify de novo and rare variants involved in autism

Chen, R., Davis, L. K., Guter, S. J., Wei, Q., Jacob, S., Potter, M. H., Cox, N. J., Cook, E. H., Sutcliffe, J. S., & Li, B. (2017) · Molecular Autism · doi:10.1186/s13229-017-0130-3 · Cited by 57 · see citing works

Drosophilamutants of the autism candidategene neurobeachin(rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, and impaired adult social behavior and activity patterns

Wise, A., Tenezaca, L., Fernandez, R. W., Schatoff, E. M., Flores, J., Ueda, A., Zhong, X., Wu, C., Simon, A. F., & Venkatesh, T. (2015) · Journal of Neurogenetics · doi:10.3109/01677063.2015.1064916 · Cited by 54 · see citing works

A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5

Zamurrad, S., Hatch, H. A. M., Drelon, C., Belálcazar, H. M., & Secombe, J. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.02.018 · Cited by 53 · see citing works

The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors

Neyen, C. D., Runchel, C., Schüpfer, F., Meier, P., & Lemaître, B. (2016) · Nature Immunology · doi:10.1038/ni.3536 · Cited by 49 · see citing works

Landscape of protein–protein interactions in Drosophila immune deficiency signaling during bacterial challenge

Fukuyama, H., Verdier, Y., Guan, Y., Makino‐Okamura, C., Shilova, V. Y., Liu, X., Maksoud, É., Matsubayashi, J., Haddad, I., Spirohn, K., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1304380110 · Cited by 45 · see citing works

Automated Quantification of Locomotion, Social Interaction, and Mate Preference in Drosophila Mutants

Iyengar, A. S. R., Imoehl, J., Ueda, A., Nirschl, J., & Wu, C. (2012) · Journal of Neurogenetics · doi:10.3109/01677063.2012.729626 · Cited by 44 · see citing works

Microdeletion of the escape genes KDM5C and IQSEC2 in a girl with severe intellectual disability and autistic features

Fieremans, N., Esch, H. V., de Ravel, T. J. L., Driessche, J. V., Belet, S., Bauters, M., & Froyen, G. (2015) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2015.03.003 · Cited by 33 · see citing works

The Histone Demethylase KDM5 Is Essential for Larval Growth in Drosophila

Drelon, C., Belálcazar, H. M., & Secombe, J. (2018) · Genetics · doi:10.1534/genetics.118.301004 · Cited by 31 · see citing works

Using Animal Models to Study the Role of the Gut–Brain Axis in Autism

Nithianantharajah, J., Balasuriya, G. K., Franks, A. E., & Hill‐Yardin, E. L. (2017) · Current Developmental Disorders Reports · doi:10.1007/s40474-017-0111-4 · Cited by 28 · see citing works

Conditions Affecting Social Space in Drosophila melanogaster

McNeil, A. R., Jolley, S. N., Akinleye, A. A., Nurilov, M., Rouzyi, Z., Milunovich, A. J., Chambers, M. C., & Simon, A. F. (2015) · Journal of Visualized Experiments · doi:10.3791/53242 · Cited by 26 · see citing works

Patient Mutations of the Intellectual Disability Gene KDM5C Downregulate Netrin G2 and Suppress Neurite Growth in Neuro2a Cells

Wei, G., Deng, X., Agarwal, S., Iwase, S., Distèche, C. M., & Xu, J. (2016) · Journal of Molecular Neuroscience · doi:10.1007/s12031-016-0770-3 · Cited by 25 · see citing works

A subset of neurons controls the permeability of the peritrophic matrix and midgut structure in Drosophila adults

Kenmoku, H., Ishikawa, H., Oté, M., Kuraishi, T., & Kurata, S. (2016) · Journal of Experimental Biology · doi:10.1242/jeb.122960 · Cited by 21 · see citing works

Inducing RNAi in Drosophila Cells by Transfection with dsRNAPreprint

Zhou, R., Mohr, S. E., Hannon, G. J., & Perrimon, N. (2013) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot074351 · Cited by 21 · see citing works

Towards understanding the genetics of Autism

Ouhtit, A. (2016) · Frontiers in Bioscience-Elite · doi:10.2741/776 · Cited by 17 · see citing works

Straightforward Assay for Quantification of Social Avoidance in Drosophila melanogaster

Fernandez, R. W., Nurilov, M., Feliciano, O., McDonald, I. S., & Simon, A. F. (2014) · Journal of Visualized Experiments · doi:10.3791/52011 · Cited by 13 · see citing works

Impact of the Chromatin Remodeling Factor CHD1 on Gut Microbiome Composition of Drosophila melanogaster

Johanna, S., Willi, M., Schoberleitner, I., Krogsdam, A., Orth‐Höller, D., Trajanoski, Z., & Lusser, A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153476 · Cited by 12 · see citing works

Methods to Assess Intestinal Stem Cell Activity in Response to Microbes in Drosophila melanogaster

Houtz, P., & Buchon, N. S. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1453-1_14 · Cited by 6 · see citing works

The Microbiota-Gut-Brain Axis

Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286 · see citing works

Microbiota in health and diseases

Hou, K., Wu, Z.-X., Chen, X.-Y., Wang, J.-Q., Zhang, D., Xiao, C., Zhu, D., Koya, J. B., Wei, L., Li, J., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00974-4 · Cited by 3,171 · see citing works

Short chain fatty acids: Microbial metabolites for gut-brain axis signalling

O’Riordan, K. J., Collins, M., Moloney, G. M., Knox, E. G., Aburto, M. R., Fülling, C., Morley, S. J., Clarke, G. A., Schellekens, H., & Cryan, J. F. (2022) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2022.111572 · Cited by 742 · see citing works

Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T cell immunity

Zhang, Q., Zhao, Q., Li, T., Lu, L., Wang, F., Zhang, H., Liu, Z., Ma, H., Zhu, Q., Wang, J., et al. (2023) · Cell Metabolism · doi:10.1016/j.cmet.2023.04.015 · Cited by 483 · see citing works

Gut–Brain Axis: Role of Gut Microbiota on Neurological Disorders and How Probiotics/Prebiotics Beneficially Modulate Microbial and Immune Pathways to Improve Brain Functions

Kanmani, S., & Koo, B. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207551 · Cited by 381 · see citing works

The microbiota–gut–brain axis and neurodevelopmental disorders

Wang, Q., Yang, Q., & Liu, X. (2023) · Protein & Cell · doi:10.1093/procel/pwad026 · Cited by 407 · see citing works

Gut Akkermansia muciniphila ameliorates metabolic dysfunction-associated fatty liver disease by regulating the metabolism of L-aspartate via gut-liver axis

Rao, Y., Kuang, Z., Li, C., Guo, S., Xu, Y., Zhao, D., Hu, Y., Song, B., Jiang, Z., Ge, Z., et al. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1927633 · Cited by 356 · see citing works

Microbiota Metabolites in Health and Disease

McCarville, J. L., Chen, G. Y., Cuevas, V. D., Troha, K., & Ayres, J. S. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-071219-125715 · Cited by 251 · see citing works

Effect of fecal microbiota transplantation on neurological restoration in a spinal cord injury mouse model: involvement of brain-gut axis

Jing, Y., Yu, Y., Bai, F., Wang, L., Yang, D., Zhang, C., Qin, C., Yang, M., Zhang, D., Zhu, Y., et al. (2021) · Microbiome · doi:10.1186/s40168-021-01007-y · Cited by 225 · see citing works

The emerging role of KDM5A in human cancer

Yang, G., Zhu, M., Lu, X., Liu, Y., Lu, J., Leung, C., Ma, D., & Chen, J. (2021) · Journal of Hematology & Oncology · doi:10.1186/s13045-021-01041-1 · Cited by 116 · see citing works

Unraveling host regulation of gut microbiota through the epigenome–microbiome axis

Pepke, M. L., Hansen, S. B., & Limborg, M. T. (2024) · Trends in Microbiology · doi:10.1016/j.tim.2024.05.006 · Cited by 117 · see citing works

A Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior

Cheng, L., Wu, H., Cai, X., Zhang, Y., Yu, S., Hou, Y., Yin, Z., Yan, Q., Wang, Q., Sun, T., et al. (2024) · Cell Host & Microbe · doi:10.1016/j.chom.2023.12.009 · Cited by 114 · see citing works

Microbiota-brain interactions: Moving toward mechanisms in model organisms

Nagpal, J. K., & Cryan, J. F. (2021) · Neuron · doi:10.1016/j.neuron.2021.09.036 · Cited by 107 · see citing works

Intestinal infection regulates behavior and learning via neuroendocrine signaling

Singh, J., & Aballay, A. (2019) · eLife · doi:10.7554/elife.50033 · Cited by 108 · see citing works

The gut microbiota — brain axis of insects

Liberti, J., & Engel, P. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2020.01.004 · Cited by 104 · see citing works

Dietary Pattern, Gut Microbiota, and Alzheimer’s Disease

Zhang, M., Zhao, D., Zhou, G., & Li, C. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b08309 · Cited by 106 · see citing works

Autism Spectrum Disorders and the Gastrointestinal Tract: Insights into Mechanisms and Clinical Relevance

Hung, L. Y., & Margolis, K. G. (2024) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-023-00857-1 · Cited by 96 · see citing works

Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8+/− mouse model of ASD-like behavior

Yu, Y., Zhang, B., Ji, P., Zuo, Z., Huang, Y., Wang, N., Liu, C., Liu, S., & Zhao, F. (2022) · Nature Communications · doi:10.1038/s41467-022-28746-2 · Cited by 89 · see citing works

Microbiomes as modulators of Drosophila melanogaster homeostasis and disease

Lesperance, D. N. A., & Broderick, N. A. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2020.03.003 · Cited by 83 · see citing works

Fecal and Serum Metabolomic Signatures and Microbial Community Profiling of Postmenopausal Osteoporosis Mice Model

Wen, K., Tao, L., Tao, Z., Meng, Y., Zhou, S., Chen, J., Yang, K., Da, W., & Zhu, Y. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.535310 · Cited by 77 · see citing works

Gene variations in Autism Spectrum Disorder are associated with alternation of gut microbiota, metabolites and cytokines

Liu, Z., Mao, X., Zhou, D., Pei, Y., Xu, R., Guo, M., Liu, K., Zhang, F., Chen, J., Su, C., et al. (2021) · Gut Microbes · doi:10.1080/19490976.2020.1854967 · Cited by 74 · see citing works

Probiotics for Neurodegenerative Diseases: A Systemic Review

Ojha, S., Patil, N., Jain, M., Kole, C., & Kaushik, P. (2023) · Microorganisms · doi:10.3390/microorganisms11041083 · Cited by 77 · see citing works

How commensal microbes shape the physiology of Drosophila melanogaster

Grenier, T., & Leulier, F. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2020.08.002 · Cited by 72 · see citing works

Chromatin dynamics and histone modifications in intestinal microbiota-host crosstalk

Fellows, R., & Varga‐Weisz, P. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.12.005 · Cited by 72 · see citing works

Alteration of Gut Microbiota: New Strategy for Treating Autism Spectrum Disorder

Liu, J., Gao, Z., Chuanqi, L., Liu, T., Gao, J., Cai, Y., & Fan, X. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.792490 · Cited by 62 · see citing works

Microbiota-gut-brain axis in autism spectrum disorder

Yu, Y., & Zhao, F. (2021) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2021.07.001 · Cited by 63 · see citing works

Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation

Vallianatos, C. N., Raines, B., Porter, R. S., Bonefas, K. M., Wu, M. C., Garay, P. M., Collette, K. M., Seo, Y. A., Dou, Y., Keegan, C. E., et al. (2020) · Communications Biology · doi:10.1038/s42003-020-1001-6 · Cited by 53 · see citing works

Advancements in Lactiplantibacillus plantarum : probiotic characteristics, gene editing technologies and applications

Zhang, Z., Niu, H., Qu, Q., Guo, D., Wan, X., Yang, Q., Mo, Z., Tan, S., Xiang, Q., Xue, T., et al. (2025) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2024.2448562 · Cited by 57 · see citing works

The microbiota promotes social behavior by modulating microglial remodeling of forebrain neurons

Bruckner, J. J., Stednitz, S. J., Grice, M. Z., Zaidan, D., Massaquoi, M. S., Larsch, J., Tallafuß, A., Guillemin, K. J., Washbourne, P., & Eisen, J. S. (2022) · PLoS Biology · doi:10.1371/journal.pbio.3001838 · Cited by 52 · see citing works

Marine Natural Products: Promising Candidates in the Modulation of Gut-Brain Axis towards Neuroprotection

Fakhri, S., Yarmohammadi, A., Yarmohammadi, M., Farzaei, M. H., & Echeverría, J. (2021) · Marine Drugs · doi:10.3390/md19030165 · Cited by 51 · see citing works

Intestine-derived α-synuclein initiates and aggravates pathogenesis of Parkinson’s disease in Drosophila

Liu, W., Lim, K., & Tan, E. (2022) · Translational Neurodegeneration · doi:10.1186/s40035-022-00318-w · Cited by 49 · see citing works

Ruminococcaceae_UCG-013 Promotes Obesity Resistance in Mice

Feng, J., Ma, H., Huang, Y., Li, J., & Li, W. (2022) · Biomedicines · doi:10.3390/biomedicines10123272 · Cited by 49 · see citing works

Compartmentalized PGRP expression along the dipteran Bactrocera dorsalis gut forms a zone of protection for symbiotic bacteria

Yao, Z., Cai, Z., Ma, Q., Bai, S., Wang, Y., Zhang, P., Guo, Q., Gu, J., Lemaître, B., & Zhang, H. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111523 · Cited by 49 · see citing works

The Role of Microbiota in Drosophila melanogaster Aging

Arias-Rojas, A., & Iatsenko, I. (2022) · Frontiers in Aging · doi:10.3389/fragi.2022.909509 · Cited by 47 · see citing works

Akkermansia muciniphila and Lactobacillus plantarum ameliorate systemic lupus erythematosus by possibly regulating immune response and remodeling gut microbiota

Guo, M., Lü, M., Chen, K., Xu, R. C., Xia, Y., Liu, X., Liu, Z., & Liu, Q. (2023) · mSphere · doi:10.1128/msphere.00070-23 · Cited by 47 · see citing works

Pharmacological inhibition of KDM5A for cancer treatment

Yang, G., Wu, J., Miao, L., Zhu, M., Zhou, Q., Lu, X., Lu, J., Leung, C., Ma, D., & Chen, J. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.113855 · Cited by 46 · see citing works

Histone demethylase KDM5B licenses macrophage-mediated inflammatory responses by repressing Nfkbia transcription

Zhang, Y., Gao, Y., Jiang, Y., Ding, Y., Chen, H., Yan, X. Y., Zhan, Z., & Liu, X. (2023) · Cell Death and Differentiation · doi:10.1038/s41418-023-01136-x · Cited by 44 · see citing works

New insights into irritable bowel syndrome pathophysiological mechanisms: contribution of epigenetics

Dothel, G., Barbaro, M. R., Vito, A. D., Ravegnini, G., Gorini, F., Monesmith, S., Coschina, E., Benuzzi, E., Fuschi, D., Palombo, M., et al. (2023) · Journal of Gastroenterology · doi:10.1007/s00535-023-01997-6 · Cited by 46 · see citing works

Unveiling the role of gut-brain axis in regulating neurodegenerative diseases: A comprehensive review

Yadav, H., Jaldhi, Bhardwaj, R., Anamika, A., Bakshi, A., Gupta, S., & Maurya, S. K. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122022 · Cited by 46 · see citing works

The Drosophila gut: A gatekeeper and coordinator of organism fitness and physiology

Colombani, J., & Andersen, D. S. (2020) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.378 · Cited by 44 · see citing works

The Many Faces of Microbiota-Gut-Brain Axis in Autism Spectrum Disorder

Gonçalves, C. L., Doifode, T., Rezende, V. L., Costa, M. A., Rhoads, J. M., & Soutullo, C. A. (2024) · Life Sciences · doi:10.1016/j.lfs.2023.122357 · Cited by 42 · see citing works

Inflammation in Mental Disorders: Is the Microbiota the Missing Link?

Marin, S., Hé, Y., Butler, K., & Tsuang, M. T. (2020) · Neuroscience Bulletin · doi:10.1007/s12264-020-00535-1 · Cited by 41 · see citing works

Epigenetic regulation of post-embryonic development

Palli, S. R. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2020.09.011 · Cited by 41 · see citing works

Insect–microbe interactions and their influence on organisms and ecosystems

Holt, J. R., de Oliveira, N. C., Medina, R. F., Malacrinò, A., & Lindsey, A. R. I. (2024) · Ecology and Evolution · doi:10.1002/ece3.11699 · Cited by 40 · see citing works

Gut microbiota shapes social dominance through modulating HDAC2 in the medial prefrontal cortex

Wang, T., Xu, J., Xu, Y., Xiao, J., Bi, N., Gu, X., & Wang, H.-L. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110478 · Cited by 38 · see citing works

Axenic and gnotobiotic insect technologies in research on host–microbiota interactions

Wu, J., Wang, Q., Wang, D., Wong, A. C.-N., & Wang, G.-H. (2023) · Trends in Microbiology · doi:10.1016/j.tim.2023.02.007 · Cited by 40 · see citing works

Lactobacillus plantarum L168 improves hyperoxia-induced pulmonary inflammation and hypoalveolarization in a rat model of bronchopulmonary dysplasia

Shen, X., Yang, Z., Wang, Q., Chen, X., Zhu, Q., Liu, Z., Patel, N. D., Liu, X., & Mo, X. (2024) · npj Biofilms and Microbiomes · doi:10.1038/s41522-024-00504-w · Cited by 37 · see citing works

Drosophila Model for Studying Gut Microbiota in Behaviors and Neurodegenerative Diseases

Chiang, M.-H., Ho, S.-M., Wu, H.-Y., Lin, Y.-C., Tsai, W.-H., Wu, T., Lai, C., & Wu, C. (2022) · Biomedicines · doi:10.3390/biomedicines10030596 · Cited by 37 · see citing works

The histone demethylase KDM5 controls developmental timing in Drosophila by promoting prothoracic gland endocycles

Drelon, C., Rogers, M. F., Belálcazar, H. M., & Secombe, J. (2019) · Development · doi:10.1242/dev.182568 · Cited by 35 · see citing works

Local Necrotic Cells Trigger Systemic Immune Activation via Gut Microbiome Dysbiosis in Drosophila

Kosakamoto, H., Yamauchi, T., Akuzawa-Tokita, Y., Nishimura, K., Soga, T., Murakami, T., Mori, H., Yamamoto, K., Miyazaki, R., Koto, A., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.107938 · Cited by 35 · see citing works

Gut microbes and host behavior: The forgotten members of the gut-microbiome

Weiner, A., Turjeman, S. C., & Koren, O. (2023) · Neuropharmacology · doi:10.1016/j.neuropharm.2023.109453 · Cited by 33 · see citing works

Multi-omics data reveals the disturbance of glycerophospholipid metabolism and linoleic acid metabolism caused by disordered gut microbiota in PM2.5 gastrointestinal exposed rats

Zhang, Y., Li, M., Pu, Z., Chi, X., & Yang, J. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.115182 · Cited by 33 · see citing works

Molecular and cellular events linking variants in the histone demethylase KDM5C to the intellectual disability disorder Claes‐Jensen syndrome

Hatch, H. A. M., & Secombe, J. (2021) · FEBS Journal · doi:10.1111/febs.16204 · Cited by 32 · see citing works

Molecular Rationale of Insect-Microbes Symbiosis—From Insect Behaviour to Mechanism

Singh, S., Singh, A. K., Baweja, V., Roy, A., Chakraborty, A., & Singh, I. K. (2021) · Microorganisms · doi:10.3390/microorganisms9122422 · Cited by 33 · see citing works

Fecal Microbiota Transplantation in Autism Spectrum Disorder

Li, Y., Wang, Y., & Zhang, T. (2022) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s382571 · Cited by 33 · see citing works

A KDM5–Prospero transcriptional axis functions during early neurodevelopment to regulate mushroom body formation

Hatch, H. A. M., Belálcazar, H. M., Marshall, O. J., & Secombe, J. (2021) · eLife · doi:10.7554/elife.63886 · Cited by 32 · see citing works

Exposure to cytarabine causes side effects on adult development and physiology and induces intestinal damage via apoptosis in Drosophila

Han, S., Xiu, M., Li, S., Shi, Y., Wang, X., Lin, X., Cai, H., Liu, Y., & He, J. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.114265 · Cited by 31 · see citing works

Gut microbiota mediates the absorption of FLZ, a new drug for Parkinson's disease treatment

Shang, J., Ma, S., Zang, C., Bao, X., Wang, Y., & Zhang, D. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.01.009 · Cited by 31 · see citing works

Nutrient Sensing via Gut in Drosophila melanogaster

Chopra, G., Kaushik, S., & Kain, P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052694 · Cited by 30 · see citing works

The Epigenetics of Aging in Invertebrates

Yu, G., Wu, Q., Gao, Y., Chen, M., & Yang, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20184535 · Cited by 29 · see citing works

The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction

Belálcazar, H. M., Hendricks, E. L., Zamurrad, S., Liebl, F. L. W., & Secombe, J. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108753 · Cited by 28 · see citing works

Epigenetic enzymes: A role in aging and prospects for pharmacological targeting

PASYUKOVA, E. G., Symonenko, A. V., Rybina, O. Y., & Vaiserman, A. M. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101312 · Cited by 27 · see citing works

The Effect of Limosilactobacillus reuteri on Social Behavior Is Independent of the Adaptive Immune System

Dooling, S. W., Sgritta, M., Wang, I.-C., Duque, A. L. R. F., & Costa‐Mattioli, M. (2022) · mSystems · doi:10.1128/msystems.00358-22 · Cited by 28 · see citing works

Gut microbiota influences onset of foraging-related behavior but not physiological hallmarks of division of labor in honeybees

Liberti, J., Frank, E. T., Kay, T., Kesner, L., Monié--Ibanes, M., Quinn, A., Schmitt, T., Keller, L., & Engel, P. (2024) · mBio · doi:10.1128/mbio.01034-24 · Cited by 27 · see citing works

The lipid-lowering effects of fenugreek gum, hawthorn pectin, and burdock inulin

Wang, Y., Zheng, Y., Liu, Y., Shan, G., Zhang, B., Cai, Q., Lou, J., & Qu, Y. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1149094 · Cited by 26 · see citing works

Maternal-infant probiotic transmission mitigates early-life stress-induced autism in mice

Qing, L., Qian, X., Zhu, H., Wang, J., Sun, J., Jin, Z., Tang, X., Zhao, Y., Wang, G., Zhao, J., et al. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2456584 · Cited by 26 · see citing works

Microbiota-derived metabolites in the epigenetic regulation of the host

Lei, J., Wang, X., & Liu, X. (2025) · 中国科学通报：英文版 · doi:10.1016/j.scib.2025.09.030 · Cited by 27 · see citing works

Transcriptional regulation in model organisms: recent progress and clinical implications

Tang, J., Xu, Z., Huang, L., Luo, H., & Zhu, X. M. (2019) · Open Biology · doi:10.1098/rsob.190183 · Cited by 21 · see citing works

Male‐Specific Activation of Lysine Demethylases 5B and 5C Mediates Alcohol‐Induced Liver Injury and Hepatocyte Dedifferentiation

Schonfeld, M. P., Averilla, J. N., Gunewardena, S., Weinman, S. A., & Tikhanovich, I. (2022) · Hepatology Communications · doi:10.1002/hep4.1895 · Cited by 21 · see citing works

Biglycan regulated colorectal cancer progress by modulating enteric neuron-derived IL-10 and abundance of Bacteroides thetaiotaomicron

Xu, Y., Wang, F., Mi, K., Wang, X., Wang, D., Zhao, Q., Wang, J., Liu, Z., Zhang, Q., Liu, Y., et al. (2023) · iScience · doi:10.1016/j.isci.2023.107515 · Cited by 21 · see citing works

The gut-microbiota-brain axis in autism: what Drosophila models can offer?

Salim, S., Banu, A., Alwa, A., Gowda, S. B. M., & Mohammad, F. (2021) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-021-09378-x · Cited by 19 · see citing works

Combined treatment with Rg1 and adipose-derived stem cells alleviates DSS-induced colitis in a mouse model

Zhang, R., Zhang, Q., Chen, Y., Zhao, Q., Zhang, B., Wang, L., Zhou, C., Zhang, Q., Chen, K., Zhang, Y., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02940-x · Cited by 20 · see citing works

Lead exposure results in defective behavior as well as alteration of gut microbiota composition in flies and their offsprings

Sun, Y., Tang, Y., Xu, X., Hu, K., Zhang, Z., Zhang, Y., Yi, Z., Zhu, Q., Xu, R., Zhang, Y., et al. (2020) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10067 · Cited by 20 · see citing works

Comparative Genomic Analysis of Lactiplantibacillus plantarum: Insights into Its Genetic Diversity, Metabolic Function, and Antibiotic Resistance

Li, R., & Bi, C. (2025) · Genes · doi:10.3390/genes16080869 · Cited by 19 · see citing works

Influence of Serratia marcescens and Rhodococcus rhodnii on the Humoral Immunity of Rhodnius prolixus

Batista, K. K. S., Vieira, C. S., Figueiredo, M. B., Costa, S., Azambuja, P., Genta, F. A., & de Castro, D. P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010901 · Cited by 19 · see citing works

Sleep loss impairs intestinal stem cell function and gut homeostasis through the modulation of the GABA signalling pathway in Drosophila

Zhou, J., He, L., Liu, M., Guo, X., Du, G., Yan, L., Zhang, Z., Zhong, Z.-D., & Chen, H. (2023) · Cell Proliferation · doi:10.1111/cpr.13437 · Cited by 18 · see citing works

Dephosphorylation of T517 on Hemocyanin Is Required for Antibacterial Activity in Penaeus vannamei

Feng, Q., Aweya, J. J., Huang, Y., Zhang, P., Wang, F., Yao, D., Zheng, Z., Li, E., & Zhang, Y. (2023) · The Journal of Immunology · doi:10.4049/jimmunol.2200598 · Cited by 19 · see citing works

Larval microbiota primes the Drosophila adult gustatory response

Montanari, M., Manière, G., Berthelot‐Grosjean, M., Dusabyinema, Y., Gillet, B., Grosjean, Y., Kurz, C. L., & Royet, J. (2024) · Nature Communications · doi:10.1038/s41467-024-45532-4 · Cited by 19 · see citing works

Host–diet–microbiota interplay in intestinal nutrition and health

Ignatiou, A., & Pitsouli, C. (2024) · FEBS Letters · doi:10.1002/1873-3468.14966 · Cited by 20 · see citing works

Soma‐to‐germline transformation in chromatin‐linked neurodevelopmental disorders?

Bonefas, K. M., & Iwase, S. (2021) · FEBS Journal · doi:10.1111/febs.16196 · Cited by 18 · see citing works

Alcohol‐associated fibrosis in females is mediated by female‐specific activation of lysine demethylases KDM5B and KDM5C

Schonfeld, M. P., Averilla, J. N., Gunewardena, S., Weinman, S. A., & Tikhanovich, I. (2022) · Hepatology Communications · doi:10.1002/hep4.1967 · Cited by 18 · see citing works

Vitamin B12 ameliorates gut epithelial injury via modulating the HIF-1 pathway and gut microbiota

Feng, C., Yan, J., Luo, T., Zhang, H., Zhang, H., Yu, Y., Chen, Y., & Chen, H. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05435-5 · Cited by 17 · see citing works

Treatment with Bacterial Biologics Promotes Healthy Aging and Traumatic Brain Injury Responses in Adult Drosophila, Modeling the Gut–Brain Axis and Inflammation Responses

Molina, B., Mastroianni, J., Suarez, E., Soni, B., Forsberg, E. M., & Finley, K. D. (2021) · Cells · doi:10.3390/cells10040900 · Cited by 17 · see citing works

Whole genome sequencing of nearly isogenic WMI and WLI inbred rats identifies genes potentially involved in depression and stress reactivity

de Jong, T. V., Kim, P., Guryev, V., Mulligan, M. K., Williams, R. W., Redei, E. E., & Chen, H. (2021) · Scientific Reports · doi:10.1038/s41598-021-92993-4 · Cited by 17 · see citing works

Impact of Microorganisms and Parasites on Neuronally Controlled Drosophila Behaviours

Montanari, M., & Royet, J. (2021) · Cells · doi:10.3390/cells10092350 · Cited by 17 · see citing works

Social environment drives sex and age‐specific variation in Drosophila melanogaster microbiome composition and predicted function

Leech, T., McDowall, L., Hopkins, K., Sait, S. M., Harrison, X. A., & Bretman, A. J. (2021) · Molecular Ecology · doi:10.1111/mec.16149 · Cited by 16 · see citing works

Intestinal GCN2 controls Drosophila systemic growth in response to Lactiplantibacillus plantarum symbiotic cues encoded by r/tRNA operons

Grenier, T., Consuegra, J., Ferrarini, M. G., Akherraz, H., Bai, L., Dusabyinema, Y., Rahioui, I., Silva, P. D., Gillet, B., Hughes, S., et al. (2023) · eLife · doi:10.7554/elife.76584 · Cited by 16 · see citing works

Pinobanksin ameliorated DSS-induced acute colitis mainly through modulation of SLC7A11/glutathione-mediated intestinal epithelial ferroptosis

Bi, H.-L., Guo, S., Wang, Y., Liu, Z., Wu, G., Huo, X., Li, G., Guo, H., & Xiong, Y. (2024) · Food & Function · doi:10.1039/d3fo04500e · Cited by 16 · see citing works

Honeybee gut microbiota modulates host behaviors and neurological processesPreprint

Zhang, Z., Mu, X., Cao, Q., Shi, Y., Hu, X., & Zheng, H. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.19.423587 · Cited by 15 · see citing works

The gut microbiome shapes social behaviour across animal species

Griffiths, J. A., Nirmalkar, K., Wu, W., Krajmalnik‐Brown, R., & Mazmanian, S. K. (2025) · Nature Reviews Microbiology · doi:10.1038/s41579-025-01262-y · Cited by 15 · see citing works

The Role of Gut Microbiota in Aging and Aging Related Neurodegenerative Disorders: Insights from Drosophila Model

Kong, Y., Wang, L., & Jiang, B. (2021) · Life · doi:10.3390/life11080855 · Cited by 14 · see citing works

How Gut Microbes Nurture Intestinal Stem Cells: A Drosophila Perspective

Neophytou, C., & Pitsouli, C. (2022) · Metabolites · doi:10.3390/metabo12020169 · Cited by 13 · see citing works

Thallium(I) exposure perturbs the gut microbiota and metabolic profile as well as the regional immune function of C57BL/6 J mice

Li, D., Yao, H., Zhu, X., Li, Z., & Zeng, X. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-22145-2 · Cited by 12 · see citing works

Role of Synbiotics in Reproductive Disorders

Thapa, R., Gilhotra, R. M., Bhat, A. A., Purohit, M., Kulshrestha, R., Singla, N., & Gupta, G. (2024) · Springer eBooks · doi:10.1007/978-981-99-5575-6_8 · Cited by 12 · see citing works

Stroke and Distal Organ Damage: Exploring Brain-Kidney Crosstalk

Dulam, V., Katta, S., & Nakka, V. P. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04126-8 · Cited by 11 · see citing works

Finasteride Alleviates High Fat Associated Protein-Overload Nephropathy by Inhibiting Trimethylamine N-Oxide Synthesis and Regulating Gut Microbiota

Wang, Z., You, L., Ren, Y., Zhu, X., Mao, X., Liang, X., Wang, T., Guo, Y., Liu, T., & Xue, J. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.900961 · Cited by 11 · see citing works

Synthetic microbial consortia for the treatment of Clostridioides difficile infection in mice model

Liu, J., Zhu, W., Lessing, D. J., & Chu, W. (2023) · Microbial Biotechnology · doi:10.1111/1751-7915.14333 · Cited by 10 · see citing works

DVT: a high-throughput analysis pipeline for locomotion and social behavior in adult Drosophila melanogaster

Mi, K., Li, Y., Yang, Y., Secombe, J., & Liu, X. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01125-0 · Cited by 10 · see citing works

Inferior social hierarchy is vulnerable to anxiety-like behavior in chronic pain mice: Potential role of gut microbiota and metabolites

Wang, Y., Zhang, X., Yao, Y., Hu, S.-W., Wang, W., Wang, D., Huang, C., Liu, H., Zhang, Q., He, T., et al. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106402 · Cited by 10 · see citing works

Microbiota-Based Interventions Differentially Rescue Gut and Social Behavior Phenotypes in Drosophila with Kdm5 Deficiency

Martinez, N. A. P., Arnaldi, M. R., Santiago-Rodriguez, T. M., & Rodriguez‐Fernandez, I. A. (2026) · Developmental Neuroscience · doi:10.1159/000552681

Microbiota-Based Interventions Differentially Rescue Gut and Social Behavior Phenotypes in a Drosophila Autism-like ModelPreprint

Martinez, N. A. P., Arnaldi, M. R., Santiago-Rodríguez, T. M., & Rodriguez‐Fernandez, I. A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.09.698713

The Histone H3K4 Demethylase KDM5 Modulate Gut Microbiota Composition to Affect Social Behavior

Chen, K., Liu, Q., Qiu, C., Wang, J., Luan, X., Dan, Z., Chang, X., & Liu, X. (2017) · Gastroenterology · doi:10.1016/s0016-5085(17)32836-6

Kismet/CHD7/CHD8 affects gut microbiota, mechanics, and the gut-brain axis in Drosophila melanogaster

Niosi, A., Võ, N. H., Sundaramurthy, P., Welch, C. J., Penn, A., Yuldasheva, Y., Alfareh, A., Rausch, K., Amin-Rahbar, T., Cavanaugh, J., et al. (2024) · Biophysical Journal · doi:10.1016/j.bpj.2024.06.016 · Cited by 3 · see citing works

Drosophila as a Model for Microbiota Studies of Neurodegeneration

Kitani‐Morii, F., Friedland, R. P., Yoshida, H., & Mizuno, T. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-215031 · Cited by 26 · see citing works