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Supercritical fluid extraction: Recent advances and applications
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Among the different extraction techniques used at analytical and preparative scale, supercritical fluid extraction (SFE) is one of the most used. This review covers the most recent developments of SFE in different fields, such as food science, natural products, by-product recovery, pharmaceutical and environmental sciences, during the period 2007-2009. The revision is focused on the most recent advances and applications in the different areas; among them, it is remarkable the strong impact of SFE to extract high value compounds from food and natural products but also its increasing importance in areas such as heavy metals recovery, enantiomeric resolution or drug delivery systems.
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“The main supercritical solvent used is CO2, which is accessible, environmentally friendly, and generally recognized as safe by the U.S. Food and Drug Administration [31].”
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Metadata
- Authors
- Herrero, M., Mendiola, J. A., Cifuentes, A., & Ibáñez, E.
- Affiliations
- Instituto de Fermentaciones Industriales (ES)
- Corresponding author
- Ibáñez, Elena
- Venue
- Journal of Chromatography A
- Publisher
- Elsevier BV
- Published
- 2010-04
- Volume
- 1217
- Issue
- 16
- Pages
- 2495-2511
- ISSN
- 0021-9673 (ISSN-L)
- OpenAlex
- W2028488322
- Cited by
- 849
- References
- 247
- Citations by year
- 2026: 57 · 2025: 86 · 2024: 76 · 2023: 54 · 2022: 46 · 2021: 59 · 2020: 46 · 2019: 57 · 2018: 54 · 2017: 46 · 2016: 49 · 2015: 42 · 2014: 41 · 2013: 47 · 2012: 47
- FWCI
- 2.58
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Journal of Chromatography A (publishedVersion)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, other-oa)
- Topics
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Phase Equilibria and Thermodynamics
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Chemistry and Chromatography
- Keywords
- supercritical fluid extraction, food analysis, natural products, by-product recovery, pharmaceutical applications, environmental analysis, heavy metal recovery, enantiomer resolution, drug delivery systems, value-added chemicals
- MeSH terms
- Biological Products, Pharmaceutical Preparations, Environmental Pollutants, Food Analysis, Chemical Fractionation, Metals, Heavy
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