Antimicrobial Activity of Sub- and Supercritical CO2 Extracts of the Green Alga Dunaliella salina
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The objective of this research was to evaluate the antimicrobial activity of carbon dioxide extracts of the unicellular biflagellated green alga Dunaliella salina against Escherichia coli, Staphylococcus aureus, Candida albicans, and Aspergillus niger. The effects of different extraction pressures ranging from 185 to 442 bar and extraction temperatures ranging from 9.8 to 45.2 degrees C on the extracts' composition and consequently on their antimicrobial activities were investigated. The extracts were analyzed by gas chromatography-mass spectrometry in order to identify the compounds responsible for the antimicrobial activity detected. Fourteen different volatile compounds and several fatty acids were identified. The highest antimicrobial activity was obtained using 314 bar and 9.8 degrees C. Under these conditions, the presence of an indolic derivative that had never been reported in D. salina was detected in the extract, together with polyunsaturated fatty acids and compounds related to carotene metabolism, such as beta-ionone and neophytadiene, with known antimicrobial activity.
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Dunaliella salina produces compounds that are active against several bacterial and fungus strains.
“Dunaliella salina also produces compounds that are active against several bacterial and fungus strains (e.g., Staphylococcus aureus, Escherichia coli, Candida albicans, Psuedomonas aeruginosa, Aspergillus niger) [259].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [259]
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Khadim, S. R., Mohanta, A., Maurya, P., Singh, P., & Asthana, R. K. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-820655-3.00008-2 · Cited by 3 · see citing works
Issues Regarding Toxicity and Safety of Foods from Seaweeds
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Red Algal Bioactive Compounds and their Nutraceutical Application: An Overview
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Valorisation des activités biologiques de la diatomée marine Haslea ostrearia
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- Authors
- Mendiola, J. A., Santoyo, S., Cifuentes, A., Reglero, G., Ibáñez, E., & Señoráns, F. J.
- Affiliations
- Universidad Autónoma de Madrid (ES)
- Instituto de Fermentaciones Industriales (ES)
- Corresponding author
- Santoyo, Susana
- ORCID
- Venue
- Journal of Food Protection
- Publisher
- Elsevier BV
- Published
- 2008-10
- Volume
- 71
- Issue
- 10
- Pages
- 2138-2143
- ISSN
- 0362-028X (ISSN-L)
- OpenAlex
- W2439381583
- Cited by
- 80
- References
- 31
- Citations by year
- 2025: 4 · 2024: 4 · 2023: 4 · 2022: 10 · 2021: 5 · 2020: 8 · 2019: 5 · 2018: 7 · 2017: 2 · 2016: 3 · 2015: 8 · 2014: 5 · 2013: 4 · 2012: 4
- FWCI
- 3.52
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Food Protection (publishedVersion, other-oa)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (acceptedVersion, other-oa)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, other-oa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Keywords
- Dunaliella salina, antimicrobial activity, subcritical CO2 extraction, supercritical CO2 extraction, green algae extract, Escherichia coli, Staphylococcus aureus, Candida albicans, Aspergillus niger, extraction pressure, extraction temperature, volatile compounds, fatty acids, β-ionone, neophytadiene, carotene metabolism, polyunsaturated fatty acids
- MeSH terms
- Chlorophyta, Anti-Bacterial Agents, Aspergillus niger, Candida albicans, Carbon Dioxide, Dose-Response Relationship, Drug, Escherichia coli, Food Preservation, Gas Chromatography-Mass Spectrometry, Microbial Sensitivity Tests, Oils, Volatile, Plant Extracts, Staphylococcus aureus, Colony Count, Microbial, Food, Organic
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