Cited by 80Seaweed-derived Bioactive CompoundsEssential Oils and Antimicrobial ActivityAlgal biology and biofuel production

Antimicrobial Activity of Sub- and Supercritical CO2 Extracts of the Green Alga Dunaliella salina

Open access
Mendiola, Jose A., Santoyo, Susana, Cifuentes, Alejandro, Reglero, Guillermo, Ibáñez, Elena, Señoráns, F.Javier·2008·Journal of Food Protection

Abstract

The objective of this research was to evaluate the antimicrobial activity of carbon dioxide extracts of the unicellular biflagellated green alga Dunaliella salina against Escherichia coli, Staphylococcus aureus, Candida albicans, and Aspergillus niger. The effects of different extraction pressures ranging from 185 to 442 bar and extraction temperatures ranging from 9.8 to 45.2 degrees C on the extracts' composition and consequently on their antimicrobial activities were investigated. The extracts were analyzed by gas chromatography-mass spectrometry in order to identify the compounds responsible for the antimicrobial activity detected. Fourteen different volatile compounds and several fatty acids were identified. The highest antimicrobial activity was obtained using 314 bar and 9.8 degrees C. Under these conditions, the presence of an indolic derivative that had never been reported in D. salina was detected in the extract, together with polyunsaturated fatty acids and compounds related to carotene metabolism, such as beta-ionone and neophytadiene, with known antimicrobial activity.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.4315/0362-028x-71.10.2138

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Mendiola, J. A., Santoyo, S., Cifuentes, A., Reglero, G., Ibáñez, E., & Señoráns, F. J.
Affiliations
  • Universidad Autónoma de Madrid (ES)
  • Instituto de Fermentaciones Industriales (ES)
Corresponding author
Santoyo, Susana
Venue
Journal of Food Protection
Publisher
Elsevier BV
Published
2008-10
Volume
71
Issue
10
Pages
2138-2143
ISSN
0362-028X (ISSN-L)
OpenAlex
W2439381583
Cited by
80
References
31
Citations by year
2025: 4 · 2024: 4 · 2023: 4 · 2022: 10 · 2021: 5 · 2020: 8 · 2019: 5 · 2018: 7 · 2017: 2 · 2016: 3 · 2015: 8 · 2014: 5 · 2013: 4 · 2012: 4
FWCI
3.52
Type
journal article
Language
en
Open access
Locations
  • Journal of Food Protection (publishedVersion, other-oa)
  • PubMed (publishedVersion)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (acceptedVersion, other-oa)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, other-oa)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
  • Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
Keywords
Dunaliella salina, antimicrobial activity, subcritical CO2 extraction, supercritical CO2 extraction, green algae extract, Escherichia coli, Staphylococcus aureus, Candida albicans, Aspergillus niger, extraction pressure, extraction temperature, volatile compounds, fatty acids, β-ionone, neophytadiene, carotene metabolism, polyunsaturated fatty acids
MeSH terms
Chlorophyta, Anti-Bacterial Agents, Aspergillus niger, Candida albicans, Carbon Dioxide, Dose-Response Relationship, Drug, Escherichia coli, Food Preservation, Gas Chromatography-Mass Spectrometry, Microbial Sensitivity Tests, Oils, Volatile, Plant Extracts, Staphylococcus aureus, Colony Count, Microbial, Food, Organic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review