Cited by 59Hepatitis C virus researchTryptophan and brain disordersCOVID-19 and Mental Health

Chronic hepatitis C virus infection and depression

Adinolfi, Luigi Elio, Nevola, Riccardo, Rinaldi, Luca, Romano, Ciro, Giordano, Mauro·2017·Clinics in Liver Disease

Abstract

Hepatitis C virus (HCV) infection is a systemic disease with hepatic and extrahepatic manifestations, including neuropsychiatric conditions. Depression is a frequent disorder, which has been reported in one-third of patients with HCV infection and has an estimated prevalence of 1.5 to 4.0 times higher than that observed in patients with chronic hepatitis B virus infection or the general population. HCV seems to play a direct and indirect role in the development of depression. Impaired quality of life and increasing health care costs have been reported for patients with HCV infection with depression. Treatment-induced HCV clearance has been associated with improvement of depression and quality of life.

Integrity signals

Registry

Crossref · 10.1016/j.cld.2017.03.007

Cites

139 of 139 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

1 of the 140 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Adinolfi, L. E., Nevola, R., Rinaldi, L., Romano, C., & Giordano, M.
Affiliations
University of Campania "Luigi Vanvitelli" (IT)
Corresponding author
Adinolfi, Luigi Elio
Venue
Clinics in Liver Disease
Publisher
Elsevier BV
Published
2017-08
Volume
21
Issue
3
Pages
517-534
ISSN
1089-3261 (ISSN-L)
OpenAlex
W2608662514
Cited by
59
References
140
Citations by year
2026: 2 · 2025: 1 · 2024: 5 · 2023: 7 · 2022: 9 · 2021: 11 · 2020: 8 · 2019: 7 · 2018: 8 · 2017: 1
FWCI
0.95
Type
journal article
Language
en
Open access
closed
Locations
  • Clinics in Liver Disease (publishedVersion)
  • PubMed (publishedVersion)
  • Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli" (submittedVersion)
  • Archivio Istituzionale della Ricerca - Università degli Studi del Molise (submittedVersion)
Topics
  • Health Sciences › Medicine › Hepatology › Hepatitis C virus research
  • Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
  • Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
Keywords
hepatitis C virus, chronic hepatitis C, depression, neuropsychiatric symptoms, extrahepatic manifestations, quality of life, health care costs, antiviral therapy, HCV clearance, depression prevalence
MeSH terms
Antidepressive Agents, Antiviral Agents, Central Nervous System, Depression, Humans, Quality of Life, Prevalence, Hepacivirus, Hepatitis C, Chronic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review