Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
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- The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibitionJessica Brandi, Daniela Cecconi, Marco Cordani, Margalida Torrens‐Mas, Raffaella Pacchiana, Elisa Dalla Pozza, Giovanna Butera, Marcello Manfredi, Emílio Marengo, Jordi Oliver et al. · 2016 · Free Radical Biology and Medicine
- UCP 2 gene polymorphisms in obesity and diabetes, and the role of UCP 2 in cancerJinran Li, Rihua Jiang, Xianling Cong, Yunfeng Zhao · 2019 · FEBS Letters
- Metabolic Reprogramming in Dietary RestrictionRozalyn M. Anderson, Richard H. Weindruch · 2006 · KARGER eBooks
- Further Support to the Uncoupling-to-Survive Theory: The Genetic Variation of Human UCP Genes Is Associated with LongevityGiuseppina Rose, Paolina Crocco, Francesco De Rango, Alberto Montesanto, Giuseppe Passarino · 2011 · PLoS ONE
- Bisphenol-A induces neurodegeneration through disturbance of intracellular calcium homeostasis in human embryonic stem cells-derived cortical neuronsHongou Wang, Peiqiang Zhao, Qiansheng Huang, Yulang Chi, Sijun Dong, Jianglin Fan · 2019 · Chemosphere
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- Association between obesity and insulin resistance with UCP2–UCP3 gene variants in Spanish children and adolescentsMaría Carmen Ochoa, José Luis Santos, Cristina Azcona, María Jesús Moreno-Aliaga, Miguel Ángel Martínez‐González, José Alfredo Martínez, Amelia Martí · 2007 · Molecular Genetics and Metabolism
- An ancient look at UCP1Martin Klingenspor, Tobias Fromme, David A. Hughes, Lars H. Manzke, Elias T. Polymeropoulos, Tobias Riemann, Magdalene Trzcionka, Verena Hirschberg, Martin Jastroch · 2008 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Role of Uncoupling Proteins in CancerAdamo Valle, Jordi Oliver, Pilar Roca · 2010 · Cancers
- Both ischemic preconditioning and ghrelin administration protect hippocampus from ischemia/reperfusion and upregulate uncoupling protein-2Yajun Liu, Lian-Bi Chen, Xiaoqun Xu, Éric Vicaut, Richard Sercombe · 2009 · BMC Physiology
- Do skeletal muscle-secreted factors influence the function of pancreatic β-cells?Jonathan P. Barlow, Thomas P. J. Solomon · 2017 · American Journal of Physiology-Endocrinology and Metabolism
- Drosophila Models of Sporadic Parkinson’s DiseaseEmi Nagoshi · 2018 · International Journal of Molecular Sciences
- Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondriaNadeene Parker, Paul G. Crichton, Antonio Vidal‐Puig, Martin D. Brand · 2009 · Journal of Bioenergetics and Biomembranes
- Maternal malnutrition programs pancreatic islet mitochondrial dysfunction in the adult offspringNicolas Theys, Marie‐Thérèse Ahn, Thomas Bouckenooghe, Brigitte Reusens, Claude Remacle · 2010 · The Journal of Nutritional Biochemistry
- UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergismIlaria Dando, Raffaella Pacchiana, Elisa Dalla Pozza, Ivana Cataldo, Stefano Bruno, Paola Conti, Marco Cordani, Anna Grimaldi, Giovanna Butera, Michele Caraglia et al. · 2017 · Free Radical Biology and Medicine
- A lncRNA-encoded mitochondrial micropeptide exacerbates microglia-mediated neuroinflammation in retinal ischemia/reperfusion injuryXintong Zheng, Mingwei Wang, Shuting Liu, Haiqiao Chen, Yifei Li, Fa Yuan, Ludong Yang, Suo Qiu, Hongwei Wang, Zhi Xie et al. · 2023 · Cell Death and Disease
- The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesisPaolo Puddu, Giovanni M. Puddu, Eleonora Cravero, Susanna De Pascalis, Antonio Muscari · 2009 · Journal of Biomedical Science
- Mitochondrial uncoupling in cancer cells: Liabilities and opportunitiesGyörgy Baffy · 2017 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Histamine receptor signaling in energy homeostasisIustin V. Tabarean · 2015 · Neuropharmacology
- UCP2, UCP3, avUCP, what do they do when proton transport is not stimulated? Possible relevance to pyruvate and glutamine metabolismFrançois Criscuolo, Julien Mozo, Corinne Hurtaud, Tobias Nübel, Frédéric Bouillaud · 2006 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Skeletal Muscle Type Comparison of Subsarcolemmal Mitochondrial Membrane Phospholipid Fatty Acid Composition in RatLeslie E. Stefanyk, Nicole S. Coverdale, Brian D. Roy, Sandra J. Peters, Paul J. LeBlanc · 2010 · The Journal of Membrane Biology
- Roles of Norepinephrine, Free Fatty Acids, Thyroid Status, and Skeletal Muscle Uncoupling Protein 3 Expression in Sympathomimetic-Induced ThermogenesisJon E. Sprague, Xianmei Yang, Joni Sommers, T. Lee Gilman, Edward Mills · 2006 · Journal of Pharmacology and Experimental Therapeutics
- ROS production in brown adipose tissue mitochondria: The question of UCP1-dependenceIrina G. Shabalina, Marek Vrbacký, Alena Pecinová, Anastasia Kalinovich, Z Drahota, J Houštěk, Tomáš Mráček, Barbara Cannon, Jan Nedergaard · 2014 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytesLonghua Liu, Zhipeng Tao, Louise Zheng, Joseph Brooke, Cayleen Smith, Dongmin Liu, Yun Chau Long, Zhiyong Cheng · 2016 · Cell Death Discovery
- Cold defence responses the role of oxidative stressDuško P. Blagojević · 2010 · Frontiers in Bioscience-Scholar
- Effects of the presence, absence, and overexpression of uncoupling protein-3 on adiposity and fuel metabolism in congenic miceSheila R. Costford, Shehla N. Chaudhry, Mahmoud Salkhordeh, Mary‐Ellen Harper · 2006 · American Journal of Physiology-Endocrinology and Metabolism
- Immune Tolerance in Mytilus galloprovincialis Hemocytes After Repeated Contact With Vibrio splendidusMagalí Rey-Campos, Rebeca Moreira, Marco Gerdol, Alberto Pallavicini, Beatriz Novoa, Antonio J. Figueras · 2019 · Frontiers in Immunology
- Glucose Transporter-8 (GLUT8) Mediates Glucose Intolerance and Dyslipidemia in High-Fructose Diet-Fed Male MiceBrian J. DeBosch, Zhouji Chen, Brian N. Finck, Maggie M.-Y. Chi, Kelle H. Moley · 2013 · Molecular Endocrinology
- Insights into the Molecular Mechanisms of the Anti-Atherogenic Actions of Flavonoids in Normal and Obese MiceElena V. Shabrova, Tarnopolsky Olga, Ajay P. Singh, Jorge Plutzky, Nicholi Vorsa, Loredana Quadro · 2011 · PLoS ONE
- An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycleJan Niemann, Cindy Johne, Susanne Schröder, Franziska Koch, Saleh Mohamed Ibrahim, Julia Schultz, Markus Tiedge, Simone Baltrusch · 2016 · Free Radical Biology and Medicine
- “Alternative” fuels contributing to mitochondrial electron transport: Importance of non-classical pathways in the diversity of animal metabolismAllison E. McDonald, Nicolas Pichaud, Charles-A. Darveau · 2017 · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology
- Mitochondrial Ca2+, the secret behind the function of uncoupling proteins 2 and 3?Wolfgang F. Graier, Michael Trenker, Roland Malli · 2008 · Cell Calcium
- Effect of exercise and calorie restriction on biomarkers of aging in miceDerek M. Huffman, Douglas R. Moellering, William E. Grizzle, Cecil R. Stockard, Maria S. Johnson, Tim R. Nagy · 2008 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Rapid turnover of mitochondrial uncoupling protein 3Vian Azzu, Shona A. Mookerjee, Martin D. Brand · 2009 · Biochemical Journal
- Mitochondria and AngiogenesisRaluca Marcu, Ying Yi Zheng, Brian John Hawkins · 2017 · Advances in experimental medicine and biology
- Genetic Variance inUncoupling Protein 2in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional −866G>A Promoter Variant (rs659366)Louise T. Dalgaard · 2011 · Journal of Obesity
- 4-Hydroxynonenal induces Nrf2-mediated UCP3 upregulation in mouse cardiomyocytesElia López-Bernardo, Andrea Anedda, Patricia Sánchez-Pérez, Bárbara Acosta‐Iborra, Susana Cadenas · 2015 · Free Radical Biology and Medicine
- Myocardial Metabolism in Diabetic Cardiomyopathy: Potential Therapeutic TargetsMiranda M. Y. Sung, Shereen M. Hamza, Jason R.B. Dyck · 2015 · Antioxidants and Redox Signaling
- Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondriaDarren A. Talbot, Martin D. Brand · 2005 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Mitochondria: The Missing Link Between Preconditioning and NeuroprotectionSónia C. Correia, Renato X. Santos, George L. Perry, Xiongwei Zhu, Paula Isabel Moreira, Mark A. Smith · 2010 · Journal of Alzheimer s Disease
- Role of Protein Carbonylation in Skeletal Muscle Mass Loss Associated with Chronic ConditionsBarreiro, Esther · 2016 · Proteomes
- Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperaturesFabian Swirplies, Sven Wuertz, Björn Baßmann, Axel M. Orban, Nadine Schäfer, Ronald M. Brunner, Frieder Hadlich, Tom Goldammer, Alexander Rebl · 2018 · Aquaculture
- Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal musclesClaire Tiraby, Geneviève Tavernier, Frédéric Capel, Aline Mairal, F. Crampes, JACQUES RAMI, C. Pujol, Jean Albert Boutin, Dominique Langin · 2007 · Diabetologia
- Mitochondria–actin cytoskeleton crosstalk in cell migrationTarun Yadav, David M. Gau, Partha Sarathi Roy · 2022 · Journal of Cellular Physiology
- Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clampsYong Qi, Kenneth A. Longo, Derek J. Giuliana, Samantha Gagne, Tom McDonagh, Elizabeth K. Govek, Anna L. Nolan, Chaoseng Zou, Kristen Morgan, Jeffrey Hixon et al. · 2011 · BMC Physiology
- Dietary fat, fatty acid saturation and mitochondrial bioenergeticsLiping P. Yu, Brian D. Fink, Judith A. Herlein, Christine L. Oltman, Kathryn Griffin Lamping, William I. Sivitz · 2013 · Journal of Bioenergetics and Biomembranes
- Modulation of mitochondrial K+ permeability and reactive oxygen species production by the p13 protein of human T-cell leukemia virus type 1Micol Silic‐Benussi, Enrica Cannizzaro, Andrea Venerando, Ilaria Cavallari, Valeria Petronilli, Nicoletta La Rocca, Oriano Marin, Luigi Chieco‐Bianchi, Fabio Di Lisa, Donna M. D’Agostino et al. · 2009 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Physiological adaptations to reproduction I. Experimentally increasing litter size enhances aspects of antioxidant defence but does not cause oxidative damage in miceMichael Garratt, Nicolas Pichaud, Edith D. Aloise King, Robert C. Brooks · 2013 · Journal of Experimental Biology
- Neural Control of Energy ExpenditureHeike Münzberg, Emily Qualls‐Creekmore, Hans‐Rudolf Berthoud, Christopher D. Morrison, Sangho Yu · 2015 · Handbook of experimental pharmacology
- G protein-coupled estrogen receptor (GPER) deficiency induces cardiac remodeling through oxidative stressHao Wang, Xuming Sun, Marina S. Lin, Carlos Maria Ferrario, Holly Van Remmen, Leanne Groban · 2018 · Translational research
- Mitochondria at the Interface Between Danger Signaling and Metabolism: Role of Unfolded Protein Responses in Chronic InflammationEva Rath, Dirk Haller · 2011 · Inflammatory Bowel Diseases
- Targeted Expression of Uncoupling Protein 2 to Mouse Liver Increases the Susceptibility to Lipopolysaccharide/Galactosamine-Induced Acute Liver Injury†Yingli Shang, Yong Liu, Lei Du, Youliang Wang, Xuan Cheng, Weiming Xiao, Xiaohui Wang, Haijing Jin, Xiao Yi Yang, Shusen Liu et al. · 2009 · Hepatology
- Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondriaPaul M. Rindler, Clair Crewe, Jolyn Fernandes, Michael T Kinter, Luke I. Szweda · 2013 · American Journal of Physiology-Heart and Circulatory Physiology
- A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin SensitivityMarc J. Tol, Roelof Ottenhoff, Marco van Eijk, Noam Zelcer, Jan Aten, Sander M. Houten, Dirk Geerts, Cindy P. A. A. van Roomen, Marlou C. Bierlaagh, Saskia S. Scheij et al. · 2016 · Diabetes
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- Energetics and longevity in birdsLindsay Furness, John Roger Speakman · 2008 · AGE
- Bioenergetic Aspects of Mitochondrial Actions of Thyroid HormonesFederica Cioffi, Antonia Giacco, Fernando Goglia, Elena Silvestri · 2022 · Cells
- Regulation of skeletal muscle mitochondrial activity by thyroid hormones: focus on the “old” triiodothyronine and the “emerging” 3,5-diiodothyronineAssunta Lombardi, María Moreno, Pieter de Lange, Susanna Iossa, Rosa Anna Busiello, Fernando Goglia · 2015 · Frontiers in Physiology
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- The Atlantic salmon’s stress- and immune-related transcriptional responses to moderate hypoxia, an incremental temperature increase, and these challenges combinedAnne Beemelmanns, Fábio S. Zanuzzo, Rebeccah M. Sandrelli, Matthew L. Rise, A. Kurt Gamperl · 2021 · G3 Genes Genomes Genetics
- An Overview of Physical Exercise and Antioxidant Supplementation Influences on Skeletal Muscle Oxidative StressShima Taherkhani, Kosar Valaei, Hamid Arazi, Katsuhiko Suzuki · 2021 · Antioxidants
- β- cell dynamics in type 2 diabetes and in dietary and exercise interventionsCheng-an Lv, Yuchen Sun, Zhe Yu Zhang, Zeyad Aboelela, Xinyuan Qiu, Zhuo‐Xian Meng · 2022 · Journal of Molecular Cell Biology
- UCP2 as a Cancer Target through Energy Metabolism and Oxidative Stress ControlAngèle Luby, Marie‐Clotilde Alves‐Guerra · 2022 · International Journal of Molecular Sciences
- UCP3 Translocates Lipid Hydroperoxide and Mediates Lipid Hydroperoxide-dependent Mitochondrial UncouplingAssunta Lombardi, Rosa Anna Busiello, Laura Napolitano, Federica Cioffi, María Moreno, Pieter de Lange, Elena Silvestri, Antonia Lanni, Fernando Goglia · 2010 · Journal of Biological Chemistry
- Diabetes and dyslipidemia: characterizing lipoprotein metabolismGERALD H. TOMKIN, Daphne Owens · 2017 · Diabetes Metabolic Syndrome and Obesity
- UCP2‐dependent improvement of mitochondrial dynamics protects against acute kidney injuryNan Qin, Ting Cai, Qingqing Ke, Qi Yuan, Jing Luo, Xiaoming Mao, Lei Jiang, Hongdi Cao, Ping Wen, Ke Zen et al. · 2018 · The Journal of Pathology
- Diazoxide-induced respiratory inhibition – a putative mitochondrial KATP channel independent mechanism of pharmacological preconditioningJan Minners, Lydia Lacerda, Derek M. Yellon, Lionel Henry Opie, Christopher John McLeod, Michael N. Sack · 2006 · Molecular and Cellular Biochemistry
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- MiR-30e-5p and MiR-15a-5p Expressions in Plasma and Urine of Type 1 Diabetic Patients With Diabetic Kidney DiseaseCristine Dieter, Taís Silveira Assmann, Aline Rodrigues Costa, Luís Henrique Santos Canani, Bianca Marmontel de Souza, Andréa Carla Bauer, Daisy Crispim · 2019 · Frontiers in Genetics
- The Role of MicroRNAs in Diabetes-Related Oxidative StressMirza Muhammad Fahd Qadir, Dagmar Klein, Silvia Álvarez-Cubela, Juan Domínguez‐Bendala, Ricardo Luis Pastori · 2019 · International Journal of Molecular Sciences
- Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat dietPauline M. Jamieson, Mark E. Cleasby, Yael Kuperman, Nicholas M. Morton, P. A. T. Kelly, David G. Brownstein, Kirsty J. Mustard, Joan M. Vaughan, R. N. Carter, CAROLINE N. HAHN et al. · 2011 · Diabetologia
- Mitochondrial function and diabetes: consequences for skeletal and cardiac muscle metabolismSchrauwen-Hinderling, Vera B., Kooi, Marianne Eline, Schrauwen, Patrick · 2016 · Antioxidants & Redox Signaling
- Protective effect of myokine IL-15 against H2O2-mediated oxidative stress in skeletal muscle cellsLi, Fengna, Li, Yinghui, Tang, Yulong, Lin, Binbin, Kong, Xiangfeng, Oladele, Oso Abimbola, Yin, Yulong · 2014 · Molecular Biology Reports
- Superoxide Anion Regulates the Mitochondrial Free Ca 2+ Through Uncoupling ProteinsZhaofei Wu, Jie Zhang, Baolu Zhao · 2009 · Antioxidants and Redox Signaling
- Anti-obesity efficacy of nanoemulsion oleoresin capsicum in obese rats fed a high-fat dietYangha Kim, Joo-Yeon Kim, Mak-Soon Lee, Sunyoon Jung, Hyunjin Joo, Chong‐Tai Kim, In-Hwan Kim, Sangjin Seo, Soojung Oh · 2014 · International Journal of Nanomedicine
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- The Role of Peroxidation of Mitochondrial Membrane Phospholipids in Pancreatic β -Cell FailureZhongmin A. Ma · 2011 · Current Diabetes Reviews
- Structure and effective charge characterization of proteins by a mobility capillary electrophoresis based methodWenjing Zhang, Haimei Wu, Rongkai Zhang, Xiang Fang, Wei Liang Xu · 2019 · Chemical Science
- Lack of UCP2 reduces fas-mediated liver injury in ob/ob mice and reveals importance of cell-specific UCP2 expressionPéter Fülöp, Zoltán Derdák, Anthony R. Sheets, Edmond Sabo, Eric P. Berthiaume, Murray B. Resnick, Jack R. Wands, György Paragh, György Baffy · 2006 · Hepatology
- Roles of Neuroglobin Binding to Mitochondrial Complex III Subunit Cytochrome c1 in Oxygen-Glucose Deprivation-Induced Neurotoxicity in Primary NeuronsZhanyang Yu, Yu Zhang, Ning Liu, Jing Yuan, Li Lin, Qichuan Zhuge, Jian Xiao, Xiaoying Wang · 2015 · Molecular Neurobiology
- UCP2‐Related Mitochondrial Pathway Participates in Oroxylin A‐Induced Apoptosis in Human Colon Cancer CellsChen Qiao, Libin Wei, Qinsheng Dai, Yuxin Zhou, Qian Yin, Zhiyu Li, Yuanming Xiao, Qinglong Guo, Na Lu · 2014 · Journal of Cellular Physiology
- Roundup ® in Zebrafish: Effects on Oxidative Status and Gene ExpressionRobson Rabelo Velasques, Juliana Zomer Sandrini, Carlos Eduardo da Rosa · 2016 · Zebrafish
- Mechanisms of diseasePaul Fernyhough, Jonathan McGavock · 2014 · Handbook of clinical neurology
- Mitochondrial Uncoupling Proteins (UCPs) as Key Modulators of ROS Homeostasis: A Crosstalk between Diabesity and Male Infertility?Bruno S. Monteiro, Laís Freire‐Brito, David F. Carrageta, Pedro Fontes Oliveira, Marco Gouveia Alves · 2021 · Antioxidants
- Diabetes or peroxisome proliferator-activated receptor α agonist increases mitochondrial thioesterase I activity in heartKristen L. King, Martin Elliot Young, János Kerner, Hazel Huang, Karen M. O’Shea, Stefan E.H. Alexson, Charles L. Hoppel, William C. Stanley · 2007 · Journal of Lipid Research
- Mitochondrial uncoupling protein‐2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age‐associated lung fibrosisSunad Rangarajan, Morgan L. Locy, Diptiman Chanda, Ashish Kurundkar, Deepali Kurundkar, Jennifer L. Larson‐Casey, Pilar Londono, Rushita Adhikari Bagchi, B. Deskin, Hanan B. Elajaili et al. · 2022 · Aging Cell
- The UCP 2 ‐866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis.Roberta Fares, Salvatore Petta, Rosa Lombardi, Stefania Grimaudo, Paola Dongiovanni, Rosaria Maria Pipitone, Raffaela Rametta, Anna Ludovica Fracanzani, Enrico Mozzi, Antonio Craxı̀ et al. · 2014 · Liver International
- Uncoupling protein-2 knockdown mediates the cytotoxic effects of cisplatinFrancisca M. Santandreu, Pilar Roca, Jordi Oliver · 2010 · Free Radical Biology and Medicine
- Insulin Resistance: A Potential New Target for Therapy in Patients with Heart FailureAaron Wong, Matlooba A. AlZadjali, Anna Maria Choy, Chim Choy Lang · 2008 · Cardiovascular Therapeutics
- Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesityFrancis P. Kuhajda, Susan M. Aja, Yajun Tu, Wan Fang Han, Susan M. Medghalchi, Rajaâ El Meskini, Leslie E. Landree, Jonathan M. Peterson, Khadija Daniels, Kody Wong et al. · 2011 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
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