Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3

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Items 101–200 of 781

1. The polymorphisms of UCP2 and UCP3 genes associated with fat metabolism, obesity and diabetes
   Jia, J.‐J., Zhang, X., Ge, C.‐R., Jois, M. · 2009 · Obesity Reviews
2. Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing
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3. p53 and glucose metabolism: an orchestra to be directed in cancer therapy
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4. β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion
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5. Plasticity of Oxidative Metabolism in Variable Climates: Molecular Mechanisms
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7. Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging
   Erich Birelli Tahara, Mario Henrique de Barros, Graciele Almeida de Oliveira, Luís Eduardo Soares Netto, Alicia Juliana Kowaltowski · 2006 · The FASEB Journal
8. High- and low-calcium-dependent mechanisms of mitochondrial calcium signalling
   András Spät, Gergő Szanda, György Csordás, György Hajnóczky · 2008 · Cell Calcium
9. Increased metabolism in the R6/2 mouse model of Huntington’s disease
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10. Mitochondrial oxidative metabolism and uncoupling proteins in the failing heart
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11. Mitochondrial subpopulations and heterogeneity revealed by confocal imaging: Possible physiological role?
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12. Uncoupling protein UCP2: When mitochondrial activity meets immunity
    Yalin Emre, Tobias Nübel · 2010 · FEBS Letters
13. Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox SignalingReviewing Editors: Jerzy Beltowski, Joseph Burgoyne, Gabor Csanyi, Sergey Dikalov, Frank Krause, Anibal Vercesi, and Jeremy Ward
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14. The Role of the Nrf2/ARE Antioxidant System in Preventing Cardiovascular Diseases
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15. Prospects for therapeutic mitochondrial transplantation
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16. The transcriptomic responses of Atlantic salmon (Salmo salar) to high temperature stress alone, and in combination with moderate hypoxia
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17. Degradation of an intramitochondrial protein by the cytosolic proteasome
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18. Adaptation and maladaptation of the heart in obesity
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19. The efficiency of cellular energy transduction and its implications for obesity
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20. Oxygen-regulated isoforms of cytochrome c oxidase have differential effects on its nitric oxide production and on hypoxic signaling
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21. A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of d-galactose-induced aging rats
    Zhengde Du, Yang Yang, Yujuan Hu, Yu Sun, Sulin Zhang, Wei Peng, Yi Zhong, Xiang Huang, Weijia Kong · 2012 · Hearing Research
22. Uncoupling protein-2 and cancer
    György Baffy · 2009 · Mitochondrion
23. Polyunsaturated fatty acids activate human uncoupling proteins 1 and 2 in planar lipid bilayers
    Valeri Beck, Martin Jabůrek, Tatiana V. Demina, Anne Rupprecht, Richard K. Porter, Petr Ježek, Elena E. Pohl · 2007 · The FASEB Journal
24. Dietary Curcumin Ameliorates Aging-Related Cerebrovascular Dysfunction through the AMPK/Uncoupling Protein 2 Pathway
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25. Circadian Control of Mitochondria in Reactive Oxygen Species Homeostasis
    Volha Mezhnina, Oghogho P. Ebeigbe, Allan Poe, Roman V. Kondratov · 2022 · Antioxidants and Redox Signaling
26. Iron Deficiency Impairs Developing Hippocampal Neuron Gene Expression, Energy Metabolism, and Dendrite Complexity
    Thomas W. Bastian, William C. von Hohenberg, Daniel J. Mickelson, Lorene M. Lanier, Michael Georgieff · 2016 · Developmental Neuroscience
27. Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity
    Andrew D. Patterson, Yatrik Madhukar Shah, Tsutomu Matsubara, Kristopher W. Krausz, Frank J. Gonzalez · 2012 · Hepatology
28. Physiological oxidative stress after arousal from hibernation in Arctic ground squirrel
    Adrienne Orr, Lonita A. Lohse, Kelly L. Drew, Marcelo Hermes‐Lima · 2009 · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
29. Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle
    Magdalene K. Montgomery, Brenna Osborne, Simon H. J. Brown, Lewin Small, Todd W. Mitchell, Gregory James Cooney, Nigel A. Turner · 2013 · Journal of Lipid Research
30. Mitochondrial (‘mild’) uncoupling and ROS production: Physiologically relevant or not?
    Shabalina, Irina G., Nedergaard, Jan · 2011 · Biochemical Society Transactions
31. SOD2 overexpression: enhanced mitochondrial tolerance but absence of effect on UCP activity
    José Silva, Irina G. Shabalina, Éric Dufour, Nataša Petrovič, Emma C. Backlund, Kjell R. Hultenby, Rolf Wibom, Jan Nedergaard, Barbara Cannon, Nils‐Göran Larsson · 2005 · The EMBO Journal
32. Diabetic Retinopathy: The Role of Mitochondria in the Neural Retina and Microvascular Disease
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33. Inactivation of UCP1 and the Glycerol Phosphate Cycle Synergistically Increases Energy Expenditure to Resist Diet-induced Obesity
    Rea P. Anunciado‐Koza, Jozef Ukropec, Robert A. Koza, Leslie P. Kozak · 2008 · Journal of Biological Chemistry
34. β-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels
    Jakob D. Wikström, Shana M. Katzman, Hibo Mohamed, Gilad Twig, Solomon A. Graf, Emma A. Heart, Anthony J. A. Molina, Barbara E. Corkey, Lina Moitoso de Vargas, Nika N. Danial et al. · 2007 · Diabetes
35. Effect of puerarin in promoting fatty acid oxidation by increasing mitochondrial oxidative capacity and biogenesis in skeletal muscle in diabetic rats
    Xiufang Chen, Lei Wang, Yong-zheng Wu, Shi-yu Song, Hai-yan Min, Yan Yang, Xuan He, Qiao Liang, Long Yi, Yong Wang et al. · 2018 · Nutrition and Diabetes
36. Uncoupling proteins, dietary fat and the metabolic syndrome
    Janis S. Fisler, Craig H. Warden · 2006 · Nutrition & Metabolism
37. Mitochondrial reprogramming through cardiac oxygen sensors in ischaemic heart disease
    Susana Cadenas, Julián Aragonés, Manuel O. Landázuri · 2010 · Cardiovascular Research
38. Reduction of body weight by dietary garlic is associated with an increase in uncoupling protein mRNA expression and activation of AMP-activated protein kinase in diet-induced obese mice
    Lee, Mak-Soon, Kim, In-Hwan, Kim, Chong-Tai, Kim, Yangha · 2011 · The Journal of Nutrition
39. FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation
    Helle Keinicke, Gao Sun, Caroline M. Junker Mentzel, Merete Fredholm, Linu Mary John, Birgitte Andersen, Kirsten Raun, Marina Kjærgaard Gerstenberg · 2020 · Endocrine Connections
40. Cold tolerance of UCP1-ablated mice: A skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects
    Irina G. Shabalina, Joris Hoeks, Tatiana V. Kramarova, Patrick Schrauwen, Barbara Cannon, Jan Nedergaard · 2010 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
41. Endothermy in birds: underlying molecular mechanisms
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42. Plant-Based Diets in the Reduction of Body Fat: Physiological Effects and Biochemical Insights
    Rami Salim Najjar, Rafaela G. Feresin · 2019 · Nutrients
43. The Uncoupling Proteins: A Systematic Review on the Mechanism Used in the Prevention of Oxidative Stress
    Jonathan Hirschenson, Emiliano Melgar-Bermudez, Ryan J. Mailloux · 2022 · Antioxidants
44. In Vitro Evidence Suggests That miR-133a-mediated Regulation of Uncoupling Protein 2 (UCP2) Is an Indispensable Step in Myogenic Differentiation
    Xi Chen, Kehui Wang, Jiangning Chen, Jigang Guo, Yuan Yin, Xing Fu Cai, Xing Guo, Guoqiang Wang, Rong Li Yang, Lingyun Zhu et al. · 2008 · Journal of Biological Chemistry
45. UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells
    Ilaria Dando, Claudia Fiorini, Elisa Dalla Pozza, Chiara Padroni, Chiara Costanzo, Marta Palmieri, Massimo Donadelli · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
46. UCP2 inhibition sensitizes breast cancer cells to therapeutic agents by increasing oxidative stress
    Daniel Gabriel Pons, Mercedes Nadal‐Serrano, Margalida Torrens‐Mas, Adamo Valle, Jordi Oliver, Pilar Roca · 2015 · Free Radical Biology and Medicine
47. The Pancreatic β-Cell: A Bioenergetic Perspective
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48. Oxidative stress and condition-dependent sexual signals: more than just seeing red
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49. Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma
    Inman, Denise M., Harun-Or-Rashid, Mohammad · 2017 · Frontiers in Neuroscience
50. Uncoupling Protein 2 in Cardiovascular Health and Disease
    Xiao Yu Tian, Shuangtao Ma, Gary Tse, Wing Tak Wong, Yü Huang · 2018 · Frontiers in Physiology
51. Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium
    David Sheikh‐Hamad · 2009 · American Journal of Physiology-Renal Physiology
52. Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2
    Yanlin Wang, Lüping Huang, Maen Abdelrahim, Qingsong Cai, Anh Lan Truong, Roger J. Bick, Brian J. Poindexter, David Sheikh‐Hamad · 2009 · Journal of Leukocyte Biology
53. Dysregulation of Mitochondrial Calcium Signaling and Superoxide Flashes Cause Mitochondrial Genomic DNA Damage in Huntington Disease
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54. Mitochondrial H + Leak and Thermogenesis
    Ambre M. Bertholet, Yuriy Kirichok · 2021 · Annual Review of Physiology
55. The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress
    Andrea Anedda, Elia López-Bernardo, Bárbara Acosta‐Iborra, M.Saadeh Suleiman, Manuel O. Landázuri, Susana Cadenas · 2013 · Free Radical Biology and Medicine
56. Reactive oxygen species and uncoupling protein 2 in pancreatic β ‐cell function
    Pi, J., Collins, S. · 2010 · Diabetes, Obesity and Metabolism
57. Uncoupling protein 2 deficiency aggravates astrocytic endoplasmic reticulum stress and nod-like receptor protein 3 inflammasome activation
    Ming Lu, Xiu‐Lan Sun, Chen Qiao, Yang Liu, Jianhua Ding, Gang Hu · 2013 · Neurobiology of Aging
58. Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice
    Susanne Schuster, Casey D. Johnson, Marie Hennebelle, Theresa Maria Holtmann, Ameer Y. Taha, Irina Kirpich, Akiko Eguchi, Christopher E. Ramsden, Bettina G. Papouchado, Craig James McClain et al. · 2018 · Journal of Lipid Research
59. AMP-Activated Protein Kinase Activation by 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) Inhibits Palmitate-Induced Endothelial Cell Apoptosis Through Reactive Oxygen Species Suppression
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60. Uncoupling Protein-2 Controls Adiponectin Gene Expression in Adipose Tissue Through the Modulation of Reactive Oxygen Species Production
    Emmanuel Chevillotte, Marta Giralt, Bruno Miroux, Daniel Ricquier, Francesc Villarroya · 2007 · Diabetes
61. Mitochondrial recoupling: a novel therapeutic strategy for cancer
    Baffy, G, Derdak, Z, Robson, S C · 2011 · British Journal of Cancer
62. Lactobacillus rhamnosus GG improves glucose tolerance through alleviating ER stress and suppressing macrophage activation in db/db mice
    Kun-Young Park, Bobae Kim, Chang‐Kee Hyun · 2015 · Journal of Clinical Biochemistry and Nutrition
63. Uncoupling proteins 1 and 2 (UCP1 and UCP2) from Arabidopsis thaliana are mitochondrial transporters of aspartate, glutamate, and dicarboxylates
    Magnus Monné, Lucia Daddabbo, David Gagneul, Toshihiro Obata, Björn Hielscher, Luigi Palmieri, Daniela Valeria Miniero, Alisdair Robert Fernie, Andreas P.M. Weber, Ferdinando Palmieri · 2018 · Journal of Biological Chemistry
64. Inhibition of UCP2 expression reverses diet‐induced diabetes mellitus by effects on both insulin secretion and action
    Cláudio T. DeSouza, ELIANA PEREIRA DE ARAUJO, Luiz Fabrízio Stoppiglia, José Rodrigo Pauli, Eduardo Rochete Ropelle, Silvana A. Rocco, Rodrigo M. Marin, Kleber Gomes Franchini, José Barreto Campello Carvalheira, Mário J. A. Saad et al. · 2007 · The FASEB Journal
65. Mitochondrial Acclimation Capacities to Ocean Warming and Acidification Are Limited in the Antarctic Nototheniid Fish, Notothenia rossii and Lepidonotothen squamifrons
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66. Ketones can become the major fuel source for the heart but do not increase cardiac efficiency
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67. Uncoupling Protein 2: A Key Player and a Potential Therapeutic Target in Vascular Diseases
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68. Oxidative Stress‐Mediated Skeletal Muscle Degeneration: Molecules, Mechanisms, and Therapies
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69. Stanniocalcin-1 Inhibits Renal Ischemia/Reperfusion Injury via an AMP-Activated Protein Kinase-Dependent Pathway
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70. Uncoupling Protein-2 Mediates DPP-4 Inhibitor-Induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress
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71. Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion
    Affourtit, Charles, Brand, Martin D. · 2008 · Biochemical Journal
72. Impact of Divergent Effects of Astaxanthin on Insulin Signaling in L6 Cells
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73. SIRT1 Is Involved in Glucocorticoid-mediated Control of Uncoupling Protein-3 Gene Transcription
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74. Transcriptional Upregulation of Mitochondrial Uncoupling Protein 2 Protects Against Oxidative Stress-Associated Neurogenic Hypertension
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75. Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine
    Dalla Pozza, Elisa, Fiorini, Claudia, Dando, Ilaria, Menegazzi, Marta, Sgarbossa, Anna, Costanzo, Chiara, Palmieri, Marta, Donadelli, Massimo · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
76. Changing the energy of an immune response.
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77. Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species
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78. Uncoupling protein 2 and metabolic diseases
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79. Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain
    Martin Jastroch, Julie A. Buckingham, Michael Helwig, Martin Klingenspor, Martin D. Brand · 2007 · Journal of Comparative Physiology B
80. Sirtuin 1 (SIRT1) and steroid hormone receptor activity in cancer
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81. Mitochondrial Ca2+ transport, permeability transition and oxidative stress in cell death: implications in cardiotoxicity, neurodegeneration and dyslipidemias
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82. Chronic blockade of nitric oxide synthesis reduces adiposity and improves insulin resistance in high fat-induced obese mice
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83. Uncoupling Protein 3 (UCP3) Modulates the Activity of Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) by Decreasing Mitochondrial ATP Production
    Umberto De Marchi, Cyril Castelbou, Nicolas Demaurex · 2011 · Journal of Biological Chemistry
84. Aspalathin, a dihydrochalcone C‐glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis
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85. Overexpression of stanniocalcin-1 inhibits reactive oxygen species and renal ischemia/reperfusion injury in mice
    Lüping Huang, Tatiana Belousova, Minyi Chen, Gabriel E. DiMattia, Dajun Liu, David Sheikh‐Hamad · 2012 · Kidney International
86. Mitochondrial medicine: entering the era of treatment
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87. Social overcrowding as a chronic stress model that increases adiposity in mice
    En-Ju Deborah Lin, Meng Sun, Eugene Choi, Daniel Magee, Colin W. Stets, Matthew J. During · 2014 · Psychoneuroendocrinology
88. Expression and putative role of mitochondrial transport proteins in cancer
    Oleksandr Lytovchenko, Edmund R.S. Kunji · 2017 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
89. On the role of uncoupling protein-2 in pancreatic beta cells
    Affourtit, Charles, Brand, Martin D. · 2008 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
90. Uncoupling protein 3 deficiency impairs myocardial fatty acid oxidation and contractile recovery following ischemia/reperfusion
    Kristin Shirey Edwards, Sadia Ashraf, Tyler M. Lomax, Jessica M. Wiseman, Michael E. Hall, Fábio Nelson Gava, John Edward Hall, Jonathan P. Hosler, Romain Harmancey · 2018 · Basic Research in Cardiology
91. Sequential changes in the signal transduction responses of skeletal muscle following food deprivation
    Pieter de Lange, Paola Farina, María Moreno, Maurizio Ragni, Assunta Lombardi, Elena Silvestri, Lavinia Burrone, Antonia Lanni, Fernando Goglia · 2006 · The FASEB Journal
92. DNA Methylation Dynamics in Atlantic Salmon (Salmo salar) Challenged With High Temperature and Moderate Hypoxia
    Anne Beemelmanns, Laia Ribas, Dafni Anastasiadi, Javier Moraleda-Prados, Fábio S. Zanuzzo, Matthew L. Rise, A. Kurt Gamperl · 2021 · Frontiers in Marine Science
93. Deep RNA Sequencing of the Skeletal Muscle Transcriptome in Swimming Fish
    Arjan P. Palstra, Sergi Beltrán, Erik Burgerhout, Sebastiaan A. Brittijn, Leonardo Julian Magnoni, Christiaan V. Henkel, Hans J. Jansen, Guido E.E.J.M. van den Thillart, Herman P. Spaink, Josep V. Planas · 2013 · PLoS ONE
94. Expression of transforming K-Ras oncogene affects mitochondrial function and morphology in mouse fibroblasts
    Ferdinando Chiaradonna, Daniela Gaglio, Marco Vanoni, Lilia Alberghina · 2006 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
95. Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress
    Helen C. Freeman, Kenju Shimomura, Roger Cox, Frances Mary Ashcroft · 2006 · Biochemical Society Transactions
96. Calcium regulation of T cell metabolism
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97. Impaired skeletal muscle mitochondrial bioenergetics and physical performance in chronic kidney disease
    Bryan R. Kestenbaum, Jorge Luis Gamboa, Sophia Z. Liu, Amir S. Ali, Eric G. Shankland, Thomas Jue, Cecilia Giulivi, Lucas Smith, Jonathan Himmelfarb, Ian H. de Boer et al. · 2020 · JCI Insight
98. Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-κB activation and oxidative stress
    Zoltán Derdák, Péter Fülöp, Edmond Sabo, Rosemarie Tavares, Eric P. Berthiaume, Murray B. Resnick, György Paragh, Jack R. Wands, György Baffy · 2006 · Carcinogenesis
99. mRNA expression of genes regulating oxidative phosphorylation in the muscle of beef cattle divergently ranked on residual feed intake
    A. K. Kelly, Sinéad M. Waters, Mark McGee, Rita G. Fonseca, Ciara A. Carberry, David Anthony Kenny · 2010 · Physiological Genomics
100. Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers
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