Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 446

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

GLP-1 receptor activation improves β cell function and survival following induction of endoplasmic reticulum stress

Open access
Yusta, Bernardo, Baggio, Laurie L., Estall, Jennifer L., Koehler, Jackie A., Holland, Dianne P., Li, Hongyun, Pipeleers, Danny, Ling, Zhidong, Drucker, Daniel J.·2006·Cell Metabolism
DOI 10.1016/j.cmet.2006.10.001
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.cmet.2006.10.001

Cites

21 of 21 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 21 references

Research works printed but not linked: 63

  1. Blais, 2004, Activating transcription factor 4 is translationally regulated by hypoxic stress, Mol. Cell. Biol., 24, 7469, 10.1128/MCB.24.17.7469-7482.2004 · DOI · Paper page
  2. Buteau, 2001, Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation, Diabetes, 50, 2237, 10.2337/diabetes.50.10.2237 · DOI · Paper page
  3. Buteau, 2004, Glucagon-like peptide-1 prevents beta cell glucolipotoxicity, Diabetologia, 47, 806, 10.1007/s00125-004-1379-6 · DOI · Paper page
  4. Butler, 2003, Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes, Diabetes, 52, 102, 10.2337/diabetes.52.1.102 · DOI · Paper page
  5. Campos, 1996, Identification of protein phosphatase-1-binding proteins by microcystin-biotin affinity chromatography, J. Biol. Chem., 271, 28478, 10.1074/jbc.271.45.28478 · DOI
  6. Chomczynski, 1987, Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal. Biochem., 162, 156, 10.1016/0003-2697(87)90021-2 · DOI · Paper page
  7. Efanova, 1998, Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration, J. Biol. Chem., 273, 33501, 10.1074/jbc.273.50.33501 · DOI · Paper page
  8. Fonseca, 2005, WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells, J. Biol. Chem., 280, 39609, 10.1074/jbc.M507426200 · DOI · Paper page
  9. Garcia, 1976, Biosynthesis of proinsulin and insulin in newborn rat pancreas. Interaction of glucose, cyclic AMP, somatostatin, and sulfonylureas on the (3H) leucine incorporation into immunoreactive insulin, J. Clin. Invest., 57, 230, 10.1172/JCI108264 · DOI
  10. Gomez, 2004, Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha, J. Biol. Chem., 279, 53937, 10.1074/jbc.M408682200 · DOI
  11. Harding, 1999, Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase, Nature, 397, 271, 10.1038/16729 · DOI · Paper page
  12. Harding, 2000, Regulated translation initiation controls stress-induced gene expression in mammalian cells, Mol. Cell, 6, 1099, 10.1016/S1097-2765(00)00108-8 · DOI · Paper page
  13. Harding, 2001, Diabetes mellitus and exocrine pancreatic dysfunction in perk−/− mice reveals a role for translational control in secretory cell survival, Mol. Cell, 7, 1153, 10.1016/S1097-2765(01)00264-7 · DOI · Paper page
  14. Harding, 2002, Transcriptional and translational control in the Mammalian unfolded protein response, Annu. Rev. Cell Dev. Biol., 18, 575, 10.1146/annurev.cellbio.18.011402.160624 · DOI · Paper page
  15. Hohmeier, 2000, Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion, Diabetes, 49, 424, 10.2337/diabetes.49.3.424 · DOI · Paper page
  16. Holz, 2004, Epac: a new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell, Diabetes, 53, 5, 10.2337/diabetes.53.1.5 · DOI · Paper page
  17. Hoorens, 1996, Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program, J. Clin. Invest., 98, 1568, 10.1172/JCI118950 · DOI · Paper page
  18. Hosokawa, 1996, Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy rats. Study using glucagonlike peptide-1 (7–37), J. Clin. Invest., 97, 180, 10.1172/JCI118387 · DOI
  19. Inoue, 1998, A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome), Nat. Genet., 20, 143, 10.1038/2441 · DOI · Paper page
  20. Iwawaki, 2004, A transgenic mouse model for monitoring endoplasmic reticulum stress, Nat. Med., 10, 98, 10.1038/nm970 · DOI · Paper page
  21. Jhala, 2003, cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2, Genes Dev., 17, 1575, 10.1101/gad.1097103 · DOI · Paper page
  22. Jiang, 2004, Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response, Mol. Cell. Biol., 24, 1365, 10.1128/MCB.24.3.1365-1377.2004 · DOI · Paper page
  23. Kaufman, 2002, The unfolded protein response in nutrient sensing and differentiation, Nat. Rev. Mol. Cell Biol., 3, 411, 10.1038/nrm829 · DOI · Paper page
  24. Kharroubi, 2004, Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress, Endocrinology, 145, 5087, 10.1210/en.2004-0478 · DOI · Paper page
  25. Kim, 2003, Development and characterization of a glucagon-like peptide 1-albumin conjugate: the ability to activate the glucagon-like peptide 1 receptor in vivo, Diabetes, 52, 751, 10.2337/diabetes.52.3.751 · DOI · Paper page
  26. Kimmerling, 1976, Locating the site(s) of insulin resistance in patients with nonketotic diabetes mellitus, Diabetes, 25, 673, 10.2337/diab.25.8.673 · DOI
  27. Koehler, 2005, The HeLa cell glucagon-like peptide-2 receptor is coupled to regulation of apoptosis and ERK1/2 activation through divergent signaling pathways, Mol. Endocrinol., 19, 459, 10.1210/me.2004-0196 · DOI
  28. Lassot, 2001, ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase, Mol. Cell. Biol., 21, 2192, 10.1128/MCB.21.6.2192-2202.2001 · DOI · Paper page
  29. Laybutt, 2002, Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia, Diabetes, 51, 413, 10.2337/diabetes.51.2.413 · DOI · Paper page
  30. Lu, 2004, Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response, J. Cell Biol., 167, 27, 10.1083/jcb.200408003 · DOI · Paper page
  31. Ma, 2002, Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response, J. Mol. Biol., 318, 1351, 10.1016/S0022-2836(02)00234-6 · DOI · Paper page
  32. Ma, 2003, Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress, J. Biol. Chem., 278, 34864, 10.1074/jbc.M301107200 · DOI · Paper page
  33. Maedler, 2005, Sulfonylurea induced beta-cell apoptosis in cultured human islets, J. Clin. Endocrinol. Metab., 90, 501, 10.1210/jc.2004-0699 · DOI · Paper page
  34. Marciniak, 2004, CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum, Genes Dev., 18, 3066, 10.1101/gad.1250704 · DOI · Paper page
  35. Miyazaki, 1990, Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms, Endocrinology, 127, 126, 10.1210/endo-127-1-126 · DOI · Paper page
  36. Novoa, 2001, Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha, J. Cell Biol., 153, 1011, 10.1083/jcb.153.5.1011 · DOI · Paper page
  37. Novoa, 2003, Stress-induced gene expression requires programmed recovery from translational repression, EMBO J., 22, 1180, 10.1093/emboj/cdg112 · DOI · Paper page
  38. Ovalle, 2004, Effect of rosiglitazone versus insulin on the pancreatic beta-cell function of subjects with type 2 diabetes, Diabetes Care, 27, 2585, 10.2337/diacare.27.11.2585 · DOI
  39. Oyadomari, 2004, Roles of CHOP/GADD153 in endoplasmic reticulum stress, Cell Death Differ., 11, 381, 10.1038/sj.cdd.4401373 · DOI · Paper page
  40. Ozcan, 2004, Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes, Science, 306, 457, 10.1126/science.1103160 · DOI · Paper page
  41. Perfetti, 2000, Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats, Endocrinology, 141, 4600, 10.1210/endo.141.12.7806 · doi:10.1210/endo.141.12.7806 · Paper page
  42. Perseghin, 2003, Cellular mechanism of insulin resistance: potential links with inflammation, Int. J. Obes. Relat. Metab. Disord., 27, S6, 10.1038/sj.ijo.0802491 · DOI · Paper page
  43. Pipeleers, 1985, A new in vitro model for the study of pancreatic A and B cells, Endocrinology, 117, 806, 10.1210/endo-117-3-806 · DOI · Paper page
  44. Pipeleers, 1986, Pancreatic B cells possess defense mechanisms against cell-specific toxicity, Proc. Natl. Acad. Sci. USA, 83, 5267, 10.1073/pnas.83.14.5267 · doi:10.1073/pnas.83.14.5267
  45. Rachman, 1996, Normalization of insulin responses to glucose by overnight infusion of glucagon-like peptide 1(7-36)amide in patients with NIDDM, Diabetes, 45, 1524, 10.2337/diab.45.11.1524 · DOI
  46. Rhodes, 2005, Type 2 diabetes-a matter of beta-cell life and death?, Science, 307, 380, 10.1126/science.1104345 · DOI · Paper page
  47. Ron, 2002, Translational control in the endoplasmic reticulum stress response, J. Clin. Invest., 110, 1383, 10.1172/JCI0216784 · DOI · Paper page
  48. Schatz, 1975, (Pro-) insulin biosynthesis and release of newly synthesized (pro-) insulin from isolated islets of rat pancreas in the presence of amino acids and sulphonylureas, Eur. J. Clin. Invest., 5, 477, 10.1111/j.1365-2362.1975.tb00480.x · DOI
  49. Scheuner, 2001, Translational control is required for the unfolded protein response and in vivo glucose homeostasis, Mol. Cell, 7, 1165, 10.1016/S1097-2765(01)00265-9 · DOI · Paper page
  50. Scheuner, 2005, Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis, Nat. Med., 11, 757, 10.1038/nm1259 · DOI · Paper page
  51. Schuit, 1991, Measuring the balance between insulin synthesis and insulin release, Biochem. Biophys. Res. Commun., 178, 1182, 10.1016/0006-291X(91)91017-7 · DOI
  52. Shen, 2004, The unfolded protein response–a stress signaling pathway of the endoplasmic reticulum, J. Chem. Neuroanat., 28, 79, 10.1016/j.jchemneu.2004.02.006 · DOI · Paper page
  53. Wang, 2002, Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice, Diabetologia, 45, 1263, 10.1007/s00125-002-0828-3 · DOI · Paper page
  54. Wang, 1999, A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse, J. Clin. Invest., 103, 27, 10.1172/JCI4431 · DOI · Paper page
  55. Wang, 1999, Glucagon-like peptide-1 regulates the beta cell transcription factor, PDX-1, in insulinoma cells, Endocrinology, 140, 4904, 10.1210/endo.140.10.7158 · DOI
  56. Wang, 2001, Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism, Endocrinology, 142, 1820, 10.1210/endo.142.5.8128 · DOI
  57. Wang, 2004, Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic (INS-1) beta-cells, Diabetologia, 47, 478, 10.1007/s00125-004-1327-5 · DOI · Paper page
  58. Wang, 2005, ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity, J. Cell Sci., 118, 3905, 10.1242/jcs.02513 · DOI · Paper page
  59. Wek, 2006, Coping with stress: eIF2 kinases and translational control, Biochem. Soc. Trans., 34, 7, 10.1042/BST0340007 · DOI · Paper page
  60. Wu, 2006, From acute ER stress to physiological roles of the unfolded protein response, Cell Death Differ., 13, 374, 10.1038/sj.cdd.4401840 · DOI · Paper page
  61. Xu, 1999, Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats, Diabetes, 48, 2270, 10.2337/diabetes.48.12.2270 · DOI · Paper page
  62. Yoshioka, 1997, A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice, Diabetes, 46, 887, 10.2337/diab.46.5.887 · DOI · Paper page
  63. Yusta, 2000, Enteroendocrine localization of GLP-2 receptor expression, Gastroenterology, 119, 744, 10.1053/gast.2000.16489 · DOI · Paper page

Cited by

See all 446

Metadata

Authors
Yusta, B., Baggio, L. L., Estall, J. L., Koehler, J. A., Holland, D. P., Li, H., Pipeleers, D., Ling, Z., & Drucker, D. J.
Venue
Cell Metabolism
Publisher
Elsevier BV
Published
2006-11
Volume
4
Issue
5
Pages
391-406
ISSN
1550-4131 (ISSN-L)
DOI
10.1016/j.cmet.2006.10.001
OpenAlex
W2022106893
Cited by
446
References
21
FWCI
6.24
Type
journal article
Language
en
Open access
bronze
Licence
Funders
  • Canada Research Chairs
  • Juvenile Diabetes Research Foundation International
  • Canadian Diabetes Association
  • National Institutes of Health
  • Canadian Institutes of Health Research

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: GLP-1 receptor activation improves β cell function and survival following induction of endoplasmic reticulum stress. https://app.cochat.ai/papers/10.1016/j.cmet.2006.10.001
The paper
Yusta, B., Baggio, L. L., Estall, J. L., Koehler, J. A., Holland, D. P., Li, H., Pipeleers, D., Ling, Z., & Drucker, D. J. (2006). GLP-1 receptor activation improves β cell function and survival following induction of endoplasmic reticulum stress. Cell Metabolism. https://doi.org/10.1016/j.cmet.2006.10.001

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.