Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat

FGF-21 as a novel metabolic regulator

Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23606 · Cited by 2,125

Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

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Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States

Badman, M. K., Pissios, P., Kennedy, A. R., Koukos, G., Flier, J. S., & Maratos-Flier, E. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.002 · Cited by 1,495

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

Xu, J., Lloyd, D. J., Hale, C., Stanislaus, S., Chen, M., Sivits, G., Vonderfecht, S., Hecht, R., Li, Y.-S., Lindberg, R. A., et al. (2009) · Diabetes · doi:10.2337/db08-0392 · Cited by 1,151

Fibroblast Growth Factor 21 Corrects Obesity in Mice

Coskun, T., Bina, H. A., Schneider, M. A., Dunbar, J. D., Hu, C. C., Chen, Y., Moller, D. E., & Kharitonenkov, A. (2008) · Endocrinology · doi:10.1210/en.2008-0816 · Cited by 1,031

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

Zhang, X., Yeung, D. C. Y., Karpisek, M., Stejskal, D., Zhou, Z.-G., Liu, F., Wong, R. L. C., Chow, W.-S., Tso, A. W. K., Lam, K. S. L., et al. (2008) · Diabetes · doi:10.2337/db07-1476 · Cited by 908

FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Potthoff, M. J., Inagaki, T., Satapati, S., Ding, X., He, T., Goetz, R., Mohammadi, M., Finck, B. N., Mangelsdorf, D. J., Kliewer, S. A., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904187106 · Cited by 704

The Circulating Metabolic Regulator FGF21 Is Induced by Prolonged Fasting and PPARα Activation in Man

Gälman, C., Lundåsen, T., Kharitonenkov, A., Bina, H. A., Eriksson, M., Hafström, I., Dahlin, M., Åmark, P., Angelin, B., & Rudling, M. (2008) · Cell Metabolism · doi:10.1016/j.cmet.2008.06.014 · Cited by 512

Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance

Chavez, A. O., Molina-Carrion, M., Abdul-Ghani, M. A., Folli, F., DeFronzo, R. A., & Tripathy, D. (2009) · Diabetes Care · doi:10.2337/dc09-0684 · Cited by 390

Molecular cloning and expression analyses of mouse βklotho, which encodes a novel Klotho family protein

Ito, S., Kinoshita, S., Shiraishi, N., Nakagawa, S., Sekine, S., Fujimori, T., & Nabeshima, Y. (2000) · Mechanisms of Development · doi:10.1016/s0925-4773(00)00439-1 · Cited by 312

Infants Uniquely Express High Levels of RBM3 and Other Cold-Adaptive Neuroprotectant Proteins in the Human Brain

Jackson, T. C., Kotermanski, S. E., & Kochanek, P. M. (2018) · Developmental Neuroscience · doi:10.1159/000493637 · Cited by 28

Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: involvement of the autocrine action of FGF21

Moure, R., Cairó, M., Morón‐Ros, S., Quesada‐López, T., Campderrós, L., Cereijo, R., Hernáez, Á., Villarroya, F., & Giralt, M. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00270.2020 · Cited by 28

Adapting to the cold: A role for endogenous fibroblast growth factor 21 in thermoregulation?

Klein Hazebroek, M., & Keipert, S. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00389 · Cited by 27

A critical appraisal of brown adipose tissue metabolism in humans

Blondin, D. P., Labbé, S. M., Turcotte, É. E., Haman, F., Richard, D., & Carpentier, A. C. (2015) · Clinical Lipidology · doi:10.2217/clp.15.14 · Cited by 29

Molecular Characterization and Mapping of Fgf21 Gene in a Foodfish Species Asian Seabass

Wang, L., Xia, J., Liu, X., Liu, P., Wan, Z. Y., & Yue, G. H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090172 · Cited by 27

PACAP is essential for the adaptive thermogenic response of brown adipose tissue to cold exposure

Diané, A., Nikolic, N., Rudecki, A. P., King, S. M., Bowie, D. J., & Gray, S. L. (2014) · Journal of Endocrinology · doi:10.1530/joe-14-0316 · Cited by 27

Brown Adipose Tissue and Browning Agents: Irisin and FGF21 in the Development of Obesity in Children and Adolescents

Pyrżak, B., Demkow, U., & Kucharska, A. M. (2015) · Advances in experimental medicine and biology · doi:10.1007/5584_2015_149 · Cited by 26

FGF21 Mimics a Fasting-Induced Metabolic State and Increases Appetite in Zebrafish

Blanco, A. M., Bertucci, J. I., & Unniappan, S. (2020) · Scientific Reports · doi:10.1038/s41598-020-63726-w · Cited by 26

Cord blood FGF21 in gestational diabetes and its relationship with postnatal growth

Megía, A., Gil-Lluís, P., Näf, S., Ceperuelo‐Mallafré, V., González-Clemente, J. M., Llauradó, G., Núñez‐Roa, C., Roche, K., Ballesteros, M., Yañez, R. E., et al. (2015) · Acta Diabetologica · doi:10.1007/s00592-014-0705-9 · Cited by 26

Fibroblast Growth Factor‐21 and the Beneficial Effects of Long‐Chain n‐3 Polyunsaturated Fatty Acids

Villarroya, J., Flachs, P., Redondo‐Angulo, I., Giralt, M., Medříková, D., Villarroya, F., Kopecký, J., & Planavila, A. (2014) · Lipids · doi:10.1007/s11745-014-3948-x · Cited by 25

Role of fibroblast growth factor 21 in gestational diabetes mellitus: A mini‐review

Yuan, D., Wu, B. J., Henry, A., Rye, K., & Ong, K. L. (2018) · Clinical Endocrinology · doi:10.1111/cen.13881 · Cited by 26

Therapeutic prospects of metabolically active brown adipose tissue in humans

Betz, M. J. (2011) · Frontiers in Endocrinology · doi:10.3389/fendo.2011.00086 · Cited by 24

Development of a long acting FGF21 analogue-albumin fusion protein and its anti-diabetic effects

Watanabe, H., Miyahisa, M., Chikamatsu, M., Nishida, K., Minayoshi, Y., Takano, M., Ichimizu, S., Kobashigawa, Y., Morioka, H., Maeda, H., et al. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.05.036 · Cited by 24

FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance

Stöhr, O., Tao, R., Miao, J., Copps, K. D., & White, M. F. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108893 · Cited by 24

Nutritional regulation of fibroblast growth factor 21: from macronutrients to bioactive dietary compounds

Pérez‐Martí, A., Sandoval, V., Marrero, P. F., Haro, D., & Relat, J. (2016) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2016-0034 · Cited by 24

The effects on weight loss and gene expression in adipose and hepatic tissues of very-low carbohydrate and low-fat isoenergetic diets in diet-induced obese mice

Yamazaki, T., Okawa, S., & Takahashi, M. M. (2016) · Nutrition & Metabolism · doi:10.1186/s12986-016-0139-1 · Cited by 25

Evolution of the Pygmy Phenotype: Evidence of Positive Selection from Genome-wide Scans in African, Asian, and Melanesian Pygmies

Migliano, A. B., Romero, I. G., Metspalu, M., Leavesley, M., Pagani, L., Antao, T., Huang, D.-W., Sherman, B. T., Siddle, K., Scholes, C., et al. (2013) · Human Biology · doi:10.1353/hub.2013.a530634 · Cited by 23

Metabolic Effects of FGF-21: Thermoregulation and Beyond

Ni, B., Farrar, J. S., Vaitkus, J. A., & Celi, F. S. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00148 · Cited by 23

Non-sympathetic control of brown adipose tissue

Cereijo, R., Villarroya, J., & Villarroya, F. (2015) · International Journal of Obesity Supplements · doi:10.1038/ijosup.2015.10 · Cited by 23

Surgery-Induced Weight Loss and Changes in Hormonally Active Fibroblast Growth Factors: a Systematic Review and Meta-Analysis

Hosseinzadeh, A., Roever, L., & Alizadeh, S. (2020) · Obesity Surgery · doi:10.1007/s11695-020-04807-7 · Cited by 22

Leptin, Acting at Central Level, Increases FGF21 Expression in White Adipose Tissue via PPARβ/δ

Mazuecos, L., Pintado, C., Rubio, B., Guisantes-Batán, E., Andrés, A., & Gallardo, N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094624 · Cited by 21

Brown Adipose Tissue

Klingenspor, M., Bast‐Habersbrunner, A., Bolze, F., Li, Y., Maurer, S., Schweizer, S., Willershäuser, M., & Fromme, T. (2017) · Springer eBooks · doi:10.1007/978-3-319-52031-5_4 · Cited by 21

Prolonged FGF21 treatment increases energy expenditure and induces weight loss in obese mice independently of UCP1 and adrenergic signaling

Stanić, S., Bardová, K., Janovská, P., Rossmeisl, M., Kopecký, J., & Zouhar, P. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116042 · Cited by 20

Hepatic FGF21 production is increased in late pregnancy in the mouse

Cui, Y., Giesy, S. L., Hassan, M., Davis, K., Zhao, S., & Boisclair, Y. R. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00554.2013 · Cited by 21

Bone morphogenic protein 9 is a novel thermogenic hepatokine secreted in response to cold exposure

Um, J., Park, S., Hur, J. H., Lee, H., Jeong, K., Cho, Y., Lee, S.-H., Yoon, S.-M., Choe, S., & Choi, C. S. (2022) · Metabolism · doi:10.1016/j.metabol.2022.155139 · Cited by 22

Nucleophosmin3 carried by small extracellular vesicles contribute to white adipose tissue browning

Zhang, Y., Yu, M., Dong, J., Wu, Y., & Tian, W. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01381-1 · Cited by 20

Adipose tissue plasticity and new therapeutic targets

Enerbäck, S. (2013) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2012.242 · Cited by 21

Effects of a maternal diet supplemented with chocolate and fructose beverage during gestation and lactation on rat dams and their offspring

Zhang, Z.-Y., Zeng, J., Kjaergaard, M., Guan, N., Raun, K., Nilsson, C., & Wang, M.-W. (2011) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2011.05568.x · Cited by 21

Isoenergetic Feeding of Low Carbohydrate-High Fat Diets Does Not Increase Brown Adipose Tissue Thermogenic Capacity in Rats

Betz, M. J., Bielohuby, M., Mauracher, B., Abplanalp, W. A., Müller, H., Pieper, K., Ramisch, J., Tschöp, M. H., Beuschlein, F., Bidlingmaier, M., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038997 · Cited by 20

FGF21 mediates the protective effect of fenofibrate against acetaminophen -induced hepatotoxicity via activating autophagy in mice

Zhang, Y., Pan, Y., Xiong, R., Zheng, J., Li, Q., Zhang, S., Li, X., Pan, X., & Yang, S. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.04.157 · Cited by 20

Detection of thermogenesis in rodents in response to anti-obesity drugs and genetic modification

Arch, J. R. S., & Trayhurn, P. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00064 · Cited by 20

Somatic Cell Plasticity and Niemann-Pick Type C2 Protein

Csepeggi, C., Jiang, M., & Frolov, A. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.135939 · Cited by 19

Breastfeeding: A Bridge to Addressing Disparities in Obesity and Health

Ramos, D. E. (2012) · Breastfeeding Medicine · doi:10.1089/bfm.2012.0076 · Cited by 19

Hormonal and nutritional signalling in the control of brown and beige adipose tissue activation and recruitment

Giralt, M., Cairó, M., & Villarroya, F. (2016) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2016.08.005 · Cited by 19

GPR120 controls neonatal brown adipose tissue thermogenic induction

Quesada‐López, T., Gavaldà‐Navarro, A., Morón‐Ros, S., Campderrós, L., Iglesias, R., Giralt, M., & Villarroya, F. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00081.2019 · Cited by 19

Endoplasmic reticulum stress at the forefront of fatty liver diseases and cancer

Karin, M., & Kim, J. Y. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100096 · Cited by 20

SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice

Mizumoto, T., Yoshizawa, T., Sato, Y., Ito, T., Tsuyama, T., Satoh, A., Araki, S., Tsujita, K., Tamura, M., Oike, Y., et al. (2022) · Cells · doi:10.3390/cells11223609 · Cited by 18

Intermittent Fasting‐Induced Orm2 Promotes Adipose Browning via the GP130/IL23R‐p38 Cascade

Zhu, X., Wang, X., Wang, J., Du, L., Zhang, Z., Zhou, D., Han, J., & Luan, B. (2024) · Advanced Science · doi:10.1002/advs.202407789 · Cited by 19

Behavioral, Hormonal, Inflammatory, and Metabolic Effects Associated with FGF21-Pathway Activation in an ALS Mouse Model

Delaye, J.-B., Lanznaster, D., Veyrat‐Durebex, C., Fontaine, A., Bacle, G., Lefèvre, A., Hergesheimer, R., Lecron, J., Vourc’h, P., Andres, C. R., et al. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00933-3 · Cited by 17

Prenatal exposure of female mice to perfluorononanoic acid delays pubertal activation of the reproductive endocrine axis through enhanced hepatic FGF21 production

Zhang, Y., Xu, Y., Ding, H., Yu, W., & Chen, L. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.128776 · Cited by 17

Exposure of male mice to perfluorooctanoic acid induces anxiety-like behaviors by increasing corticotropin-releasing factor in the basolateral amygdala complex

Wang, Y., Zhang, Y., Shi, Z., Di, T., Yu, W., & Chen, L. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2021.132170 · Cited by 17

Physiology and Endocrinology Symposium: FGF21: Insights into mechanism of action from preclinical studies1,2

Antonellis, P. J., Kharitonenkov, A., & Adams, A. C. (2014) · Journal of Animal Science · doi:10.2527/jas.2013-7076 · Cited by 15

Transcriptome Comparison Reveals the Difference in Liver Fat Metabolism between Different Sheep Breeds

Li, T., Jin, M., Fei, X., Yuan, Z., Wang, Y., Quan, K., Wang, T., Yang, J., He, M., & Wei, C. (2022) · Animals · doi:10.3390/ani12131650 · Cited by 16

Searching for ways to switch on brown fat: are we getting warmer?

Whittle, A. J. (2012) · Journal of Molecular Endocrinology · doi:10.1530/jme-12-0080 · Cited by 16

Enhanced Hepatic PPARα Activity Links GLUT8 Deficiency to Augmented Peripheral Fasting Responses in Male Mice

Mayer, A. L., Zhang, Y., Feng, E. H., Higgins, C. B., Adenekan, O., Pietka, T., Beatty, W. L., & DeBosch, B. J. (2018) · Endocrinology · doi:10.1210/en.2017-03150 · Cited by 16

Protein-caloric restriction induced HPA axis activation and altered the milk composition imprint metabolism of weaned rat offspring

Martins, I. P., Vargas, R., Saavedra, L. P. J., Rickli, S., Matiusso, C. C. I., Pavanello, A., Casagrande, L., Pastre, M. J., Oliveira, J. B., de Almeida, A. M., et al. (2022) · Nutrition · doi:10.1016/j.nut.2022.111945 · Cited by 16

Nutritional strategies for intervention of diabetes and improvement of β-cell function

Wei, S., Li, C., Wang, Z., & Chen, Y. (2023) · Bioscience Reports · doi:10.1042/bsr20222151 · Cited by 18

Somatic Cell Plasticity and Niemann-Pick Type C2 Protein

Csepeggi, C., Jiang, M., Kojima, F., Crofford, L. J., & Frolov, A. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.135897 · Cited by 14

Sexual Dimorphism in Adipose-Hypothalamic Crosstalk and the Contribution of Aryl Hydrocarbon Receptor to Regulate Energy Homeostasis

Haque, N., & Tischkau, S. A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147679 · Cited by 18

Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia

Yamanishi, K., Maeda, S., Kuwahara-Otani, S., Hashimoto, T., Ikubo, K., Mukai, K., Nakasho, K., Gamachi, N., El-Darawish, Y., Li, W., et al. (2018) · Journal of Translational Medicine · doi:10.1186/s12967-018-1684-3 · Cited by 15

Adipose Tissue, at the Core of the Action of Incretin and Glucagon-Based Anti-Obesity Drugs

Villarroya, F., Peyrou, M., & Giralt, M. (2025) · Current Obesity Reports · doi:10.1007/s13679-025-00660-w · Cited by 14

FGF21 modulates hippocampal cold-shock proteins and CA2-subregion proteins in neonatal mice with hypoxia–ischemia

Herrmann, J. R., Kochanek, P. M., Vagni, V., Janesko‐Feldman, K. L., Stezoski, J. P., Gorse, K., & Jackson, T. C. (2023) · Pediatric Research · doi:10.1038/s41390-023-02652-9 · Cited by 14

Pepper and cinnamon improve cold induced cognitive impairment via increasing non-shivering thermogenesis; a study

Pandit, C., Latha, S. S., Rani, T. U., & Anilakumar, K. R. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1511835 · Cited by 14

Gestational Ingestion of Oxidized Frying Oil by C57BL/6J Mice Differentially Affects the Susceptibility of the Male and Female Offspring to Diet-Induced Obesity in Adulthood

Chuang, H.-C., Huang, C.-F., Chang, Y.-C., Lin, Y., & Chao, P. (2013) · Journal of Nutrition · doi:10.3945/jn.112.168948 · Cited by 14

Short Dietary Intervention with Olive Oil Increases Brown Adipose Tissue Activity in Lean but not Overweight Subjects

Monfort‐Pires, M., U-Din, M., Nogueira, G. A. S., de Almeida-Faria, J., Sidarta-Oliveira, D., Sant’Ana, M. R., Júnior, J. C. D. L., Cintra, D. E., de Souza, H. P., Ferreira, S. R. G., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa824 · Cited by 14

Modulation of the Systemic Immune Response in Suckling Rats by Breast Milk TGF-β2, EGF and FGF21 Supplementation

Torres-Castro, P., Grases-Pintó, B., Abril-Gil, M., Castell, M., Rodríguez-Lagunas, M. J., Pérez-Cano, F. J., & Franch, À. (2020) · Nutrients · doi:10.3390/nu12061888 · Cited by 13

Attenuation of FGF21 signalling might aggravate the impairment of glucose homeostasis during the high sucrose diet induced transition from prediabetes to diabetes in WNIN/GR-Ob rats

Kondeti, S., Dinesh Yadav, D. M., Muralidhar, M. N., Prasad, S. M. V. K., Nemani, H., & Kalashikam, R. R. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111252 · Cited by 12

Skeletal endocrinology: where evolutionary advantage meets disease

Jaschke, N., Sipos, W., Hofbauer, L. C., Rachner, T. D., & Rauner, M. (2021) · Bone Research · doi:10.1038/s41413-021-00149-x · Cited by 13

The role of chicken ovalbumin upstream promoter transcription factor II in the regulation of hepatic fatty acid oxidation and gluconeogenesis in newborn mice

Planchais, J., Boutant, M., Fauveau, V., Lou, D.-Q., Sabra-Makke, L., Bossard, P., Vasseur-Cognet, M., & Pégorier, J. P. (2015) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00433.2014 · Cited by 13

Syndromic Insulin Resistance: Models for the Therapeutic Basis of the Metabolic Syndrome and Other Targets of Insulin Resistance

Görden, P., Zadeh, E. S., Cochran, E. K., & Brown, R. J. (2012) · Endocrine Practice · doi:10.4158/ep12139.ra · Cited by 13

Placental fibroblast growth factor 21 is not altered in late-onset preeclampsia

Nitert, M. D., Scholz‐Romero, K., Kubala, M. H., McIntyre, D. H., Callaway, L. K., & Barrett, H. L. (2015) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-015-0006-3 · Cited by 13

Endocrine and autocrine/paracrine modulators of brown adipose tissue mass and activity as novel therapeutic strategies against obesity and type 2 diabetes

Scheideler, M., Herzig, S., & Georgiadi, A. (2017) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2017-0043 · Cited by 12

From Beats to Metabolism: the Heart at the Core of Interorgan Metabolic Cross Talk

Romero-Becerra, R., Santamans, A. M., Arcones, A. C., & Sabio, G. (2023) · Physiology · doi:10.1152/physiol.00018.2023 · Cited by 12

Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2)

Guo, L., Costanzo-Garvey, D. L., Smith, D. R., Zavorka, M. E., Venable-Kang, M., MacDonald, R. G., & Lewis, R. E. (2016) · Scientific Reports · doi:10.1038/srep32093 · Cited by 11

Beyond obesity – thermogenic adipocytes and cardiometabolic health

Aldiss, P., Dellschaft, N. S., Sacks, H. S., Budge, H., & Symonds, M. E. (2017) · Hormone Molecular Biology and Clinical Investigation · doi:10.1515/hmbci-2017-0007 · Cited by 10

Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster

Lewis, J. E., Samms, R. J., Cooper, S., Luckett, J., Perkins, A. C., Adams, A. C., Tsintzas, K., & Ebling, F. J. P. (2017) · Scientific Reports · doi:10.1038/s41598-017-03607-x · Cited by 11

Bioactive Components in Human Milk Along the First Month of Life: Effects of Iodine Supplementation during Pregnancy

Velasco, I., Santos, C., Limón, J., Pascual, E., Zarza, L., Marina, E. M., Gutiérrez‐Repiso, C., & García‐Fuentes, E. (2016) · Annals of Nutrition and Metabolism · doi:10.1159/000443800 · Cited by 10

Cold adaptive thermogenesis following consumption of certain pungent spice principles: A validation study

Pandit, C., & Anilakumar, K. R. (2016) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2016.12.008 · Cited by 10

Rutaecarpine Promotes Adipose Thermogenesis and Protects against HFD-Induced Obesity via AMPK/PGC-1α Pathway

Chen, D., Duan, Y., Yu, S., Zhang, X., Li, N., & Li, J. (2022) · Pharmaceuticals · doi:10.3390/ph15040469 · Cited by 11

Averting Comfortable Lifestyle Crises

Bilton, R. F. (2013) · Science Progress · doi:10.3184/003685013x13743292107915 · Cited by 10

Mapping the response of human fibroblast growth factor 21 (FGF21) promoter to serum availability and lipoic acid in HepG2 hepatoma cells

Xia, M., Erickson, A., Yi, X., & Moreau, R. F. (2015) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2015.12.004 · Cited by 10

Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation

Vázquez, P., Hernández‐Sánchez, C., Escalona-Garrido, C., Pereira, L., Contreras, C., López, M., Balsinde, J., de Pablo, F., & Valverde, Á. M. (2018) · Journal of Lipid Research · doi:10.1194/jlr.m085209 · Cited by 10

Exposure to “Forever Chemical” perfluorooctanoic acid induces depression-like behaviors in mice by activating the HPA axis

Ya, W., Chen, Y., Chen, H., Samsom, J., Shu, M., Gao, X., Li, Q., Chen, K., Wang, L., & Liu, F. (2025) · Environment International · doi:10.1016/j.envint.2025.109631 · Cited by 9

Low expression of brown and beige fat genes in subcutaneous tissues in obese patients

Alamrani, A., Abdelkarim, M., ALZabin, M., & Alzoghaibi, M. A. (2018) · Archives of Medical Science · doi:10.5114/aoms.2018.76684 · Cited by 9

Electron Density of Adipose Tissues Determined by Phase-Contrast Computed Tomography Provides a Measure for Mitochondrial Density and Fat Content

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Adipose tissue growth and development: the modulating role of ambient temperature

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