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Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism

Suzuki, Ryo, Lee, Kevin, Jing, Enxuan, Biddinger, Sudha B., McDonald, Jeffrey G., Montine, Thomas J., Craft, Suzanne, Kahn, C. Ronald·2010·Cell Metabolism
DOI 10.1016/j.cmet.2010.11.006PMC PMC3205997
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  1. Ali, 2006, The prevalence of co-morbid depression in adults with Type 2 diabetes: a systematic review and meta-analysis, Diabet. Med., 23, 1165, 10.1111/j.1464-5491.2006.01943.x · DOI
  2. Arito, 2008, Growth factor-induced phosphorylation of sterol regulatory element-binding proteins inhibits sumoylation, thereby stimulating the expression of their target genes, low density lipoprotein uptake, and lipid synthesis, J. Biol. Chem., 283, 15224, 10.1074/jbc.M800910200 · DOI · Paper page
  3. Avruch, 2009, Amino acid regulation of TOR complex 1, Am. J. Physiol. Endocrinol. Metab., 296, E592, 10.1152/ajpendo.90645.2008 · DOI
  4. Bach, 2009, Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells, J. Biol. Chem., 284, 31260, 10.1074/jbc.M109.004382 · DOI
  5. Banks, 1997, Transport of insulin across the blood-brain barrier: saturability at euglycemic doses of insulin, Peptides, 18, 1423, 10.1016/S0196-9781(97)00231-3 · DOI
  6. Barres, 2008, The mystery and magic of glia: a perspective on their roles in health and disease, Neuron, 60, 430, 10.1016/j.neuron.2008.10.013 · DOI · Paper page
  7. Biessels, 2005, The impact of diabetes on cognition: what can be learned from rodent models?, Neurobiol. Aging, 26, 36, 10.1016/j.neurobiolaging.2005.08.015 · DOI
  8. Biessels, 2008, Cognition and diabetes: a lifespan perspective, Lancet Neurol., 7, 184, 10.1016/S1474-4422(08)70021-8 · DOI
  9. Björkhem, 2004, Brain cholesterol: long secret life behind a barrier, Arterioscler. Thromb. Vasc. Biol., 24, 806, 10.1161/01.ATV.0000120374.59826.1b · DOI · Paper page
  10. Borg, 1994, Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia, J. Clin. Invest., 93, 1677, 10.1172/JCI117150 · DOI
  11. Brüning, 2000, Role of brain insulin receptor in control of body weight and reproduction, Science, 289, 2122, 10.1126/science.289.5487.2122 · DOI · Paper page
  12. Chamberlain, 2001, SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis, Proc. Natl. Acad. Sci. USA, 98, 5619, 10.1073/pnas.091502398 · DOI
  13. Chen, 2009, Amyloid-beta interrupts the PI3K-Akt-mTOR signaling pathway that could be involved in brain-derived neurotrophic factor-induced Arc expression in rat cortical neurons, J. Neurosci. Res., 87, 2297, 10.1002/jnr.22057 · DOI
  14. Das, 2005, Electrophysiological and behavioral phenotype of insulin receptor defective mice, Physiol. Behav., 86, 287, 10.1016/j.physbeh.2005.08.024 · DOI
  15. Dietschy, 2001, Cholesterol metabolism in the brain, Curr. Opin. Lipidol., 12, 105, 10.1097/00041433-200104000-00003 · DOI · Paper page
  16. Dietschy, 2004, Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal, J. Lipid Res., 45, 1375, 10.1194/jlr.R400004-JLR200 · DOI · Paper page
  17. Evans, 2009, Statin-associated adverse cognitive effects: survey results from 171 patients, Pharmacotherapy, 29, 800, 10.1592/phco.29.7.800 · DOI
  18. Francis, 2008, Intranasal insulin prevents cognitive decline, cerebral atrophy and white matter changes in murine type I diabetic encephalopathy, Brain, 131, 3311, 10.1093/brain/awn288 · DOI
  19. Hering, 2003, Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability, J. Neurosci., 23, 3262, 10.1523/JNEUROSCI.23-08-03262.2003 · DOI
  20. Kim, 2009, GSK-3 is a master regulator of neural progenitor homeostasis, Nat. Neurosci., 12, 1390, 10.1038/nn.2408 · DOI · Paper page
  21. Kolomiytseva, 2008, Membrane lipids and morphology of brain cortex synaptosomes isolated from hibernating Yakutian ground squirrel, Comp. Biochem. Physiol. B Biochem. Mol. Biol., 151, 386, 10.1016/j.cbpb.2008.08.001 · DOI
  22. Korade, 2008, Lipid rafts, cholesterol, and the brain, Neuropharmacology, 55, 1265, 10.1016/j.neuropharm.2008.02.019 · DOI · Paper page
  23. Kotti, 2006, Brain cholesterol turnover required for geranylgeraniol production and learning in mice, Proc. Natl. Acad. Sci. USA, 103, 3869, 10.1073/pnas.0600316103 · DOI
  24. Lang, 2001, SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis, EMBO J., 20, 2202, 10.1093/emboj/20.9.2202 · DOI
  25. Lucas, 2001, Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice, EMBO J., 20, 27, 10.1093/emboj/20.1.27 · DOI
  26. Marks, 2009, Awake intranasal insulin delivery modifies protein complexes and alters memory, anxiety, and olfactory behaviors, J. Neurosci., 29, 6734, 10.1523/JNEUROSCI.1350-09.2009 · DOI · Paper page
  27. Mauch, 2001, CNS synaptogenesis promoted by glia-derived cholesterol, Science, 294, 1354, 10.1126/science.294.5545.1354 · DOI · Paper page
  28. McDonald, 2007, Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry, Methods Enzymol., 432, 145, 10.1016/S0076-6879(07)32006-5 · DOI
  29. Mitter, 2003, The synaptophysin/synaptobrevin interaction critically depends on the cholesterol content, J. Neurochem., 84, 35, 10.1046/j.1471-4159.2003.01258.x · DOI
  30. Obici, 2003, Minireview: nutrient sensing and the regulation of insulin action and energy balance, Endocrinology, 144, 5172, 10.1210/en.2003-0999 · DOI
  31. Okabe, 1999, Continual remodeling of postsynaptic density and its regulation by synaptic activity, Nat. Neurosci., 2, 804, 10.1038/12175 · DOI
  32. Porstmann, 2008, SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth, Cell Metab., 8, 224, 10.1016/j.cmet.2008.07.007 · DOI · Paper page
  33. Puglielli, 2003, Alzheimer's disease: the cholesterol connection, Nat. Neurosci., 6, 345, 10.1038/nn0403-345 · DOI · Paper page
  34. Reiss, 2004, Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease, Neurobiol. Aging, 25, 977, 10.1016/j.neurobiolaging.2003.11.009 · DOI · Paper page
  35. Rohrbough, 2005, Lipid regulation of the synaptic vesicle cycle, Nat. Rev. Neurosci., 6, 139, 10.1038/nrn1608 · DOI
  36. Rossetti, 1987, Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats, J. Clin. Invest., 79, 1510, 10.1172/JCI112981 · DOI
  37. Schubert, 2004, Role for neuronal insulin resistance in neurodegenerative diseases, Proc. Natl. Acad. Sci. USA, 101, 3100, 10.1073/pnas.0308724101 · DOI
  38. Shobab, 2005, Cholesterol in Alzheimer's disease, Lancet Neurol., 4, 841, 10.1016/S1474-4422(05)70248-9 · DOI
  39. Stefani, 2009, Cholesterol in Alzheimer's disease: unresolved questions, Curr. Alzheimer Res., 6, 15, 10.2174/156720509787313899 · DOI
  40. Suzuki, 2007, Brain-derived neurotrophic factor regulates cholesterol metabolism for synapse development, J. Neurosci., 27, 6417, 10.1523/JNEUROSCI.0690-07.2007 · DOI
  41. Taniguchi, 2006, Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta, Cell Metab., 3, 343, 10.1016/j.cmet.2006.04.005 · DOI
  42. Thiele, 2000, Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles, Nat. Cell Biol., 2, 42, 10.1038/71366 · DOI · Paper page
  43. Trudeau, 2004, Hippocampal synaptic plasticity and glutamate receptor regulation: influences of diabetes mellitus, Eur. J. Pharmacol., 490, 177, 10.1016/j.ejphar.2004.02.055 · DOI
  44. Tuccori, 2008, Statin-associated psychiatric adverse events: a case/non-case evaluation of an Italian database of spontaneous adverse drug reaction reporting, Drug Saf., 31, 1115, 10.2165/0002018-200831120-00007 · DOI
  45. Valenza, 2005, Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease, J. Neurosci., 25, 9932, 10.1523/JNEUROSCI.3355-05.2005 · DOI · Paper page
  46. Xia, 2010, Brain-derived neurotrophic factor prevents phencyclidine-induced apoptosis in developing brain by parallel activation of both the ERK and PI-3K/Akt pathways, Neuropharmacology, 58, 330, 10.1016/j.neuropharm.2009.10.009 · DOI
  47. Xie, 2009, Down-regulation of hepatic HNF4alpha gene expression during hyperinsulinemia via SREBPs, Mol. Endocrinol., 23, 434, 10.1210/me.2007-0531 · DOI
  48. Xiong, 2005, Statins and cognition: what can we learn from existing randomized trials?, CNS Spectr., 10, 867, 10.1017/S1092852900019817 · DOI

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Metadata

Authors
Suzuki, R., Lee, K., Jing, E., Biddinger, S. B., McDonald, J. G., Montine, T. J., Craft, S., & Kahn, C. R.
Venue
Cell Metabolism
Publisher
Elsevier BV
Published
2010-12
Volume
12
Issue
6
Pages
567-579
ISSN
1550-4131
DOI
10.1016/j.cmet.2010.11.006
PMC
PMC3205997
Cited by
169
References
10
Language
en
Licence
Funders
  • National Institutes of Health (33210, 60937, DK31036)
  • Alzheimer's Disease Research Center, Emory University (AG05136, GM069338, P30 DK036836)
  • Uehara Memorial Foundation

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