The DOI matches its Crossref record; 128 of the 129 references it cites were found in a registry or an index.
Metabolic Flexibility in Health and Disease
Open accessAbstract
Metabolic flexibility is the ability to respond or adapt to conditional changes in metabolic demand. This broad concept has been propagated to explain insulin resistance and mechanisms governing fuel selection between glucose and fatty acids, highlighting the metabolic inflexibility of obesity and type 2 diabetes. In parallel, contemporary exercise physiology research has helped to identify potential mechanisms underlying altered fuel metabolism in obesity and diabetes. Advances in "omics" technologies have further stimulated additional basic and clinical-translational research to further interrogate mechanisms for improved metabolic flexibility in skeletal muscle and adipose tissue with the goal of preventing and treating metabolic disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“during insulin stimulation, obese individuals and patients with T2DM are not able to increase the RER value to the same extent as lean individuals”
From Effect of Exercise Training on Fat Loss—Energetic Perspectives and the Role of Improved Adipose Tissue Function and Body Fat Distribution (2021) · cites this paper as Goodpaster and Sparks, 2017
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In the resting state, obese people have a higher RER value when compared with lean individuals, meaning a larger fraction of the energy expended derives from carbohydrate oxidation, an effect that is even more pronounced in patients with T2DM”
From Effect of Exercise Training on Fat Loss—Energetic Perspectives and the Role of Improved Adipose Tissue Function and Body Fat Distribution (2021) · cites this paper as Goodpaster and Sparks, 2017
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Metabolic flexibility, the ability to switch between fat and carbohydrate oxidation with varying energy requirements seems to be important for proper metabolic regulation”
From Effect of Exercise Training on Fat Loss—Energetic Perspectives and the Role of Improved Adipose Tissue Function and Body Fat Distribution (2021) · cites this paper as Goodpaster and Sparks, 2017
In the citing paper
“MetFlex-lip during exercise has been considered previously as the level of exercise-induced lipid oxidation, without considering lipid availability (13).”
From Metabolic flexibility to lipid availability during exercise is enhanced in individuals with high insulin sensitivity (2018) · cites this paper as [13]
In the citing paper
“As diabetes is associated with impaired metabolic flexibility [176]”
From Targeting Intramyocellular Lipids to Improve Aging Muscle Function (2025) · cites this paper as [176]
In the citing paper
“As discussed previously, metabolic flexibility relies on the action of insulin and glucagon major regulators of glucose metabolism in response to dietary stage (107) (see “Feeding/fasting”, “Biochemical transition between feeding and fasting”, and “Prolonged fasting and caloric/dietary restriction”).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [107]
In the citing paper
“great progress has been made over the past few decades to understand its underpinnings”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [107]
In the citing paper
“the body readily shifts between metabolic fuels during carbohydrate restriction to maintain energy and blood glucose”
From FGF21 and the physiological regulation of macronutrient preference (2020) · cites this paper as [37]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Role of Insulin Resistance in Human Disease
Reaven, G. M. (1988) · Diabetes · doi:10.2337/diab.37.12.1595 · Cited by 12,154
The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function
Goossens, G. H. (2017) · Obesity Facts · doi:10.1159/000471488 · Cited by 8,481
Eckel, R. H., Alberti, K., Grundy, S. M., & Zimmet, P. (2010) · The Lancet · doi:10.1016/s0140-6736(09)61794-3 · Cited by 6,317
Eckel, R. H., Grundy, S. M., & Zimmet, P. (2005) · The Lancet · doi:10.1016/s0140-6736(05)66378-7 · Cited by 5,755
Randle, P. J., Garland, P. B., Hales, C. N., & Newsholme, E. A. (1963) · The Lancet · doi:10.1016/s0140-6736(63)91500-9 · Cited by 5,093
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810
Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., & Kliewer, S. A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.12953 · Cited by 3,645
Fox, C. S., Massaro, J. M., Hoffmann, U., Pou, K. M., Maurovich-Horvat, P., Liu, C.-Y., Vasan, R. S., Murabito, J. M., Meigs, J. B., Cupples, L. A., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.675355 · Cited by 2,882
Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes
DeFronzo, R. A., & Tripathy, D. (2009) · Diabetes Care · doi:10.2337/dc09-s302 · Cited by 2,102 · cited 3×
“, 2012), and an enormous body of work supports a causal role for skeletal muscle insulin resistance in type 2 diabetes (DeFronzo and Tripathy, 2009; Petersen et al., 2007).”
Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation
Egan, B., & Zierath, J. R. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2012.12.012 · Cited by 2,084
Flagged first, then by citations
1 of the 129 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Items 701–800 of 993
Li, P., Ji, B., Lappa, D., Meijnikman, A. S., Olsson, L. M., Aydin, Ö., Bruin, S. C., van de Laar, A. W. J. M., Tremaroli, V., Luo, H., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.04.26.489057 · Cited by 3
Rizo‐Roca, D., Guimarães, D. S. P. S. F., Pendergrast, L. A., Leo, N. D., Chibalin, A., Maqdasy, S., Rydén, M., Näslund, E. B., Zierath, J. R., & Krook, A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.11.575194 · Cited by 2
Delgadillo‐Velazquez, J., Nambo‐Venegas, R., Patiño, N., Meraz‐Cruz, N., Razo-Azamar, M., Guevara‐Cruz, M., Fonseca, M., Montero, L. E. P., Ibarra‐González, I., Vela-Amieva, M. B., et al. (2021) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2021.06.007 · Cited by 1
Huang, W., Ruan, W., Huo, C., Lin, Y., Wang, T., Dai, X., Zhai, H., Ma, J., Zhang, J., Jin, L., et al. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1065188 · Cited by 3
Future Perspectives in the Management of Obesity
Garcha, S. C., & Kalra, S. (2025) · Springer eBooks · doi:10.1007/978-981-96-1651-0_6 · Cited by 1
Metabolic Flexibility as a Candidate Mechanism for the Development of Postoperative Morbidity
Arina, P., Whittle, J., Kaczorek, M. R., Ferrari, D., Tetlow, N., Dewar, A., Stephens, R. C. M., Martín, D., Moonesinghe, R., Mazomenos, E. B., et al. (2025) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000007494 · Cited by 1
Jasker, B., Dodd, D. J., Peek, C. B., & Griffith, G. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1546458 · Cited by 1
Impacts of aging on brain metabolism
Rodrigues, B. A., Santiago, T. C., & Silva, J. D. N. (2025) · Progress in brain research · doi:10.1016/bs.pbr.2025.05.009 · Cited by 2
Effects of Preoperative High-intensity Training on Metabolic Flexibility
Whittle, J., Healy, Z. R., Molinger, J., Barth, S., Molina, A. J. A., & MacLeod, D. (2025) · Anesthesiology · doi:10.1097/aln.0000000000005487 · Cited by 1
Teets, C., Etter, A. J., & Solverson, P. M. (2025) · Nutrients · doi:10.3390/nu17193142 · Cited by 1
Foreman, N. A., Rajwade, S., Bluth, J., Skoglund, L. C., Letts, A. M., DiPietro, L., Ciarleglio, A., & Barberio, M. D. (2025) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00235.2025 · Cited by 1
García-Gorrita, C., Onofre, N. S., Merino-Torres, J. F., & Soriano, J. M. (2025) · Nutrients · doi:10.3390/nu17223559 · Cited by 1
Yang, L., Liu, L., Wang, W., Ding, C., Asokan, A. K., Feng, T., Zhou, D., Xu, Z., Fu, T., Guo, Q., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-66684-x · Cited by 1
Ulk1(S555) inhibition alters nutrient stress response by prioritizing amino acid metabolism
Willoughby, O. S., Nichenko, A. S., Brisendine, M. H., Amiri, N., Henry, S. N., Braxton, D. S., Brown, J. R., Kraft, B. J., Jenkins, K. S., Addington, A. K., et al. (2025) · Molecular Metabolism · doi:10.1016/j.molmet.2025.102288 · Cited by 1
Li, Q.-H., Pesola, A. J., Brakenridge, C. J., & Gao, Y. (2025) · Sports Medicine and Health Science · doi:10.1016/j.smhs.2025.12.004 · Cited by 1
PRMT3-mediated post-translational adaptation to fasting regulates metabolic flexibility
Huang, Z., Liu, X., Chen, X., Zhou, Y., Chen, Q., Liu, Y., Zhu, H., Cheng, K., Feng, Y. Y., Dong, M., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-68883-6 · Cited by 1
Marcantei, C., Metz, L., Ramos, I., Pereira, B., Dutheil, F., Vincent, S. D. S., Duclos, M., & Isacco, L. (2026) · Physiology & Behavior · doi:10.1016/j.physbeh.2026.115262 · Cited by 1
Osborne, T. J., Rowe, G., Edgar, D. W., Fear, M. W., Wood, F. M., Fairchild, T. J., Galna, B., Kenworthy, P., & Wall, B. (2026) · European Burn Journal · doi:10.3390/ebj7010011 · Cited by 1
Abdella, F. I. A., Alardan, D., Daoud, I., Alshammari, N. S., Alrashdi, A. A., & Boudriga, S. (2026) · Future Medicinal Chemistry · doi:10.1080/17568919.2026.2636821 · Cited by 1
Metabolomic Diagnostic Technology as a Basis for the Establishing the Principles of Metabolic Health
Ivashkin, V. T., Zolnikova, O. Y., Tarasov, V. V., & Appolonova, S. A. (2026) · Russian Journal of Gastroenterology Hepatology Coloproctology · doi:10.22416/1382-4376-2025-1894-5323 · Cited by 1
Li, D. F., Morita, K., Kokaji, T., Hatano, A., Hirayama, A., Soga, T., Suzuki, Y., Matsumoto, M., Tsuchiya, T., Ozaki, H., et al. (2026) · npj Systems Biology and Applications · doi:10.1038/s41540-026-00678-3 · Cited by 1
Nesti, L., Santoni, L., Baldi, S., Scozzaro, T., Pugliese, N. R., Chiriacò, M., Sacchetta, L., Tricò, D., & Natali, A. (2026) · Diabetes Obesity and Metabolism · doi:10.1111/dom.70727 · Cited by 1
Hathiramani, N. R., Jerrett, A. E., & Spinelli, J. B. (2026) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2026.03.007 · Cited by 1
Wang, S.-N., Liu, Y.-X., Sun, G.-Y., Liu, X., Sun, Y., Ma, Y.-X., Ning, S.-Y., & Shi, Y. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1805807 · Cited by 1
Peroxisomes orchestrate metabolic flexibility and longevity via an interorganelle cascade
Sharma, A., Prabhakar, A., Valera‐Alberni, M., Kraft, J. D., Ellis, A. E., Sheldon, R. D., Mistry, M., Yao, P., Liang, Y., Hui, S. T., et al. (2026) · Nature Aging · doi:10.1038/s43587-026-01122-1 · Cited by 1
Sorokina, M. Y., Ivanova, O. A., Kostareva, A. A., & Dmitrieva, R. I. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27115016 · Cited by 1
Methnani, J., Moussa, A., Dhahbi, W., Ceylan, H. İ., Dergaa, I., Elhraiech, A., Ach, T., Latiri, I., Zaouali, M., Bouslama, A., et al. (2026) · Biomolecules · doi:10.3390/biom16070971 · Cited by 1
Phenotypic and genomic frameworks for precision pharmacotherapy in obesity: a narrative review
López-Delgado, D. S., Reyes-Zermeño, M. G., Lemus, E. D. S., Acosta-Celis, C. G., Kantún-Marín, M. A., Gomez-Lujan, M., Fallaza-Moya, K., Muñoz-Chuquilín, O., Levano, S. E. T., Gutierrez-Chavez, G., et al. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1803474 · Cited by 2
Mitochondrial dysfunction and lipid droplet dynamics in MASH: HSD17B13 as a therapeutic target
Noor, S., Tian, Y., & Su, W. (2026) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2026.1912237 · Cited by 1
Kang, S. J., Gustat, J., Tang, W., Hwang, P. H., Carmichael, O. T., Anda‐Duran, I. D., & Bazzano, L. (2026) · Journal of the American Heart Association · doi:10.1161/jaha.125.048189 · Cited by 1
Belani, J. D. (2026) · Nutrients · doi:10.3390/nu18152578 · Cited by 1
Zhou, Y., Yin, Z., Deng, X., Jiang, H., Zhou, Y., Wang, Y., Fu, L., & Tai, S. (2026) · MedComm · doi:10.1002/mco2.70910 · Cited by 1
Inorganic phosphate: a link between processed food and exercise intolerance in the modern world
Giacona, J. M., Kim, H., & Vongpatanasin, W. (2026) · Clinical Science · doi:10.1042/cs20250837 · Cited by 1
Ergothioneine: from biosynthesis to sustainable biomanufacturing and health applications
Yan, J., Dong, H., Hao, J., Ma, Y., Guoping, Z., & Zhang, Y. (2026) · Biotechnology Advances · doi:10.1016/j.biotechadv.2026.109023 · Cited by 1
Trinchese, G., Paolini, B., Cimmino, F., Valoriani, F., Lucchin, L., Bagnato, C., Sabbatini, A., Petrelli, M., Losignore, P., Marino, F., et al. (2026) · Current Nutrition Reports · doi:10.1007/s13668-026-00790-0 · Cited by 2
Gastaldelli, A., Choi, E., Conde‐Knape, K., Göransson, O., Krook, A., Lehtonen, S. H., Roden, M., Schrauwen, P., Sparks, L. M., & Heni, M. (2026) · Diabetologia · doi:10.1007/s00125-026-06853-9 · Cited by 1
Self-citationNutrición y deporte. Nuevos enfoques conceptuales en la actualidad
Pruna, R., & Lizarraga, A. (2019) · Medicina Clínica · doi:10.1016/j.medcli.2019.03.003 · Cited by 1
Blanco, A., & Blanco, G. V. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91599-1.00012-2 · Cited by 1
Katyal, G., Ebanks, B., Dowle, A., Shephard, F., Papetti, C., Lucassen, M., & Chakrabarti, L. (2022) · Biology · doi:10.3390/biology11081118 · Cited by 1
Alimentación en tiempo restringido: Efectos cardiometabólicos en adultos con exceso de peso
Bórquez, J. C., Yáñez-Barros, E., Carrera-Gil, F., & Briones, L. (2022) · Revista chilena de nutrición · doi:10.4067/s0717-75182022000500486 · Cited by 3
Ünlü, Y., Vinales, K. L., Hollstein, T., Chang, D. C., de Baca, T. C., Walter, M. F., Krakoff, J. A., & Piaggi, P. (2022) · Obesity · doi:10.1002/oby.23584 · Cited by 2
Olenick, A., Pearson, R. C., & Jenkins, N. T. (2023) · International journal of exercise science · doi:10.70252/hefm7571 · Cited by 1
Persson, A. B., & Persson, P. B. (2023) · Acta Physiologica · doi:10.1111/apha.14055 · Cited by 1
Lactate: Anaerobic Threshold and New Discoveries
Fusi, J., Scarfò, G., & Franzoni, F. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.1003067 · Cited by 2
A review on the role of novel adipokine Isthmin-1 and Subfatin in human type 2 diabetes mellitus
Abed, B. A., Farhan, L. O., Salman, I. N., & Atta, S. E. (2023) · University of Thi-Qar Journal of Science · doi:10.32792/utq/utjsci/v10i2.1129 · Cited by 1
Prior acute exercise restores postprandial fat oxidation in active cannabis users
Schubert, M. M., Terauds, S., Plant, M., Handler, G., Atkins, C., & Mendez, C. (2024) · Physiological Reports · doi:10.14814/phy2.15968 · Cited by 1
Metabolomics Tools in Antiviral Research
Soma, P. S., & Perera, R. M. (2024) · Livestock diseases and management · doi:10.1007/978-981-99-9195-2_5 · Cited by 1
Assessing metabolic flexibility response to a multifibre diet: a randomised‐controlled trial
Aubin, A., Hornero‐Ramirez, H., Ranaivo, H., Simon, C., Berghe, L. V. D., Favier, N. F., Dussous, I., Roger, L., Laville, M., Béra‐Maillet, C., et al. (2024) · Journal of Human Nutrition and Dietetics · doi:10.1111/jhn.13350 · Cited by 1
Brenmoehl, J., Meyer, Z., Walz, C., Ohde, D., & Hoeflich, A. (2024) · Cells · doi:10.3390/cells13242123 · Cited by 1
Sex- and endurance training-mediated cardiovascular protection through lipids during exercise
An, J., Thorson, A. S., Wasserman, D. H., Stafford, J. M., & Zhu, L. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.12.004 · Cited by 1
Genetically predicted basal metabolic rate and infectious diseases: a Mendelian randomization study
Li, Z., Ma, Y., Xuan, Q., Yao, Z., & Liu, Q. (2025) · Postgraduate Medical Journal · doi:10.1093/postmj/qgaf018 · Cited by 1
Role of the Glucocorticoid Receptor in Systemic Energy Metabolism
Tanaka, H., Yoshikawa, N., Yamazaki, H., Uehara, M., & Oda, A. (2018) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.107.1373 · Cited by 1
Batman, B. (2019) · SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital · doi:10.14744/semb.2019.17999 · Cited by 1
Profil Kondisi Fisik Atlet Sepaktakraw MTC (Malang Takraw Club) Kota Malang
Ardhi, D. S., & Asim, A. (2022) · Sport Science and Health · doi:10.17977/um062v2i42020p247-253 · Cited by 1
Saed, C. T., Greenwell, A. A., Dakhili, S. A. T., Gopal, K., Eaton, F., & Ussher, J. R. (2021) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2021-0559 · Cited by 1
Tsigkas, A. C. (2021) · Future of business and finance · doi:10.1007/978-3-030-81492-2_2 · Cited by 1
Olenick, A., Pearson Regis, C., & Jenkins, N. T. (2022) · International Journal of Sports and Exercise Medicine · doi:10.23937/2469-5718/1510227 · Cited by 1
Methenitis, S. K., Papadopoulou, S. Κ., Panayiotou, G., Kaprara, A., Hatzitolios, A. I., Skepastianos, P., Karali, K., & Feidantsis, K. G. (2023) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2023.01.003 · Cited by 1
Ceddia, R. P., Zurawski, Z., Gray, A. T., Adegboye, F. O., McDonald-Boyer, A., Shi, F., Liu, D., Maldonado, J., Feng, J., Li, Y., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.04.29.069138 · Cited by 1
Glucose Metabolism in Low Birth Weight Neonatal Pigs
McCauley, S. R. (2019) · VTechWorks (Virginia Tech) · Cited by 1
Connell, N. J. (2021) · Research Publications (Maastricht University) · doi:10.26481/dis.20210122nc · Cited by 1
DeBlauw, J. A., Churchill, A., Yunda, B. C., Kotarsky, C. J., Caldwell, A., & Ives, S. J. (2023) · Preprints.org · doi:10.20944/preprints202303.0257.v1
Kim, J., Jo, Y., Lim, G., Ji, Y., Roh, J., Kim, W.-G., Yi, H., Choi, D. W., Cho, D., & Ryu, D. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.13.566789 · Cited by 1
Ahn, C., Divoux, A., Zhou, M., Seldin, M. M., Sparks, L. M., & Whytock, K. L. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.23.614489 · Cited by 1
Self-citationCirculating Nonesterified Fatty Acids in Older Adults—Revisiting the Lipid–Mortality Link
Maushagen, J., & Rospleszcz, S. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf318 · Cited by 1
Koudelková, K., Moro, C., & Gojda, J. (2025) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.70068 · Cited by 1
Granero, N., Mancinetti, F., Mecocci, P., & Boccardi, V. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103416
Jannig, P. R. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.39.2018.tde-03012018-094243
Physical Excercise in the Treatment of Obesity
Sayer, R. D., & Hill, J. O. (2018) · Endocrinology · doi:10.1007/978-3-319-47685-8_29-1
Excercise in the Treatment of Obesity
Sayer, R. D., & Hill, J. O. (2018) · Endocrinology · doi:10.1007/978-3-319-47685-8_29-2
Dite, T. A. (2018) · Minerva Access (University of Melbourne)
Nutrition and Sport. New conceptual approaches today
Pruna, R., & Lizarraga, A. (2019) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2019.03.015
Post-weaning metabolic programming by dietary monosaccharides
Bouwman, L. M. S. (2019) · doi:10.18174/495333
Role of ATP1A1 in Skeletal Muscle Growth and Metabolism
Kutz, L. C. (2020)
Development of avocado derived polyhydroxylated fatty alcohols as metabolic modulators
Ahmed, N. (2019) · The Atrium (University of Guelph)
Modelling molecular processes in weight loss
Tareen, S. H. K. (2020) · doi:10.26481/dis.20200325st
Chetina, E. V., Markova, G. A., & Sharapova, E. P. (2020) · Biochemistry (Moscow) Supplement Series B Biomedical Chemistry · doi:10.1134/s1990750820020043
Clamp, L. D. (2019) · Open University of Cape Town (University of Cape Town)
Rebuttal from Bret H. Goodpaster
Goodpaster, B. H. (2020) · The Journal of Physiology · doi:10.1113/jp279714
Self-citationThe Relationship Between Diet, Body Composition, Cardiorespiratory Fitness and Respiratory Quotient
Bouchard, I. (2019) · KU ScholarWorks (University of Kansas)
Reduced ech-6 Expression Attenuates Fat-induced Premature Aging in C. elegansPreprint
Liu, Y. J., Gao, A. W., Smith, R. L., Janssens, G. E., Panneman, D. M., Jongejan, A., van Weeghel, M., Vaz, F. M., Silvestrini, M. J., Lapierre, L. R., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.02.364760
Luis Vergara, G., Lizárraga-Dallo, A., & Grivé, R. P. (2020) · Apunts Educación Física y Deportes · doi:10.5672/apunts.2014-0983.es.(2020/4).142.02
Analytical evaluation of breath acetone tubes
Ivanova, A. M., & Kolomina, E. O. (2020) · Butlerov Communications · doi:10.37952/roi-jbc-01/20-61-2-125
Páez-Franco, J. C., Torres-Ruíz, J. J., Sosa‐Hernández, V. A., Cervantes‐Díaz, R., Romero‐Ramírez, S., Pérez‐Fragoso, A., Meza-Sánchez, D. E., Germán-Acacio, J. M., Maravillas‐Montero, J. L., Mejía‐Domínguez, N. R., et al. (2020) · Research Square · doi:10.21203/rs.3.rs-92697/v1
Breath acetone as a potential marker of metabolic flexibility
Ivanova, A. M., & Ginak, A. I. (2020) · Butlerov Communications · doi:10.37952/roi-jbc-01/20-61-1-111
Metabolic Impairment Occurs Without Changes in Physical Activity in Volumetric Muscle Loss
Dalske, K. A. (2021) · University of Minnesota Digital Conservancy (University of Minnesota)
Ruffett, A. (2021) · Summit (Simon Fraser University)
Denton, N. (2021) · Oxford University Press eBooks · doi:10.1093/med/9780198865278.003.0003
ICA treatment diabets induced bone loss via primary cilia/Gli2/Osteocalcin signaling pathwayPreprint
Liu, J., Wu, X., Deng, X., Zhu, H., Wang, T., Wang, M., Yang, S., Xu, J., Chen, Q., Li, M., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.10.23.465584
School Dress Code Violations and the Ensuing Controversy.
Craig, B. L. (1970)
Targeting SWI/SNF metabolic vulnerabilities in cancer
Soeung, M., Perelli, L., Sgambato, A., & Genovese, G. (2021) · Annals of Research in Oncology · doi:10.48286/aro.2021.31
L-threonine mediated DAF-16/HSF-1 activation inhibits ferroptosis and increases healthspanPreprint
Kim, J., Jo, Y., Cho, D., & Ryu, D. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.24.477604
Su, M., Zhang, Z., Zhou, L. N., Huang, C., & Nice, E. C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819460-7.00136-5
Schreurs, V. V. A. M., Maas, T., van den Borne, J. J. G. C., & Keijer, J. (2022) · Obesities · doi:10.3390/obesities2020016
Noronha, C. M., Freitas, F. M. N. D. O., & Ferreira, J. C. D. S. (2022) · Research Society and Development · doi:10.33448/rsd-v11i5.28837
Evaluation of biochemical parameters during daytime hours
Arpacı, A. (2022) · International journal of medical biochemistry/International journal of medical biochemistry : · doi:10.14744/ijmb.2022.54227
Wilson, S. M. G., Maes, A. P., Yeoman, C. J., Walk, S. T., & Miles, M. P. (2021) · Research Square · doi:10.21203/rs.3.rs-617713/v1
Metadata
- Authors
- Goodpaster, B. H., & Sparks, L. M.
- Affiliations
- Sanford Burnham Prebys Medical Discovery Institute (US)
- Corresponding author
- Goodpaster, Bret H.
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 25
- Issue
- 5
- Pages
- 1027-1036
- ISSN
- 1550-4131 (ISSN-L)
- PMC
- PMC5513193
- OpenAlex
- W2611848952
- Cited by
- 995
- References
- 129
- Citations by year
- 2026: 150 · 2025: 131 · 2024: 89 · 2023: 126 · 2022: 138 · 2021: 133 · 2020: 106 · 2019: 72 · 2018: 42 · 2017: 6
- FWCI
- 7.58
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- American Diabetes Association
- Topics
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- metabolic flexibility, insulin resistance, fuel selection, glucose metabolism, fatty acid oxidation, obesity, type 2 diabetes, skeletal muscle, adipose tissue, exercise physiology, metabolic disorders
- MeSH terms
- Adipose Tissue, Animals, Diabetes Mellitus, Type 2, Energy Metabolism, Exercise Therapy, Fasting, Fatty Acids, Glucose, Humans, Insulin Resistance, Obesity, Rest, Exercise, Muscle, Skeletal, Caloric Restriction, Metabolic Networks and Pathways, Metabolomics, Metabolome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review