Cytokines and growth factors in airway remodeling in asthma

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

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A Critical Role for Eosinophils in Allergic Airways Remodeling

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Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics

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Interleukin‐13 in asthma pathogenesis

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Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung

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The mechanisms, diagnosis, and management of severe asthma in adults

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Inhibition of airway remodeling in IL-5–deficient mice

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Airway remodeling contributes to the progressive loss of lung function in asthma: An overview

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Mast cells can promote the development of multiple features of chronic asthma in mice

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Manipulation of Allergen-Induced Airway Remodeling by Treatment with Anti-TGF-β Antibody: Effect on the Smad Signaling Pathway

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The development of allergic inflammation

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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

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The airway epithelium: soldier in the fight against respiratory viruses

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Commonality of the IL-4/IL-13 pathway in atopic diseases

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Remodeling in asthma

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Role of Transforming Growth Factor–β in Airway Remodeling in Asthma

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Regulatory T Cells in Asthma

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Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance

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Inhaled Multiwalled Carbon Nanotubes Potentiate Airway Fibrosis in Murine Allergic Asthma

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Eosinophils in innate immunity: an evolving story

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The potential of biologics for the treatment of asthma

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Th9 and allergic disease

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Remodeling in Asthma

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Spatial and Temporal Mapping of Human Innate Lymphoid Cells Reveals Elements of Tissue Specificity

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T helper cytokines in dry eye disease

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Airway remodeling in asthma

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STAT6 and lung inflammation

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Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease

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Foxa3 Induces Goblet Cell Metaplasia and Inhibits Innate Antiviral Immunity

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The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation

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Proinflammatory and Profibrotic Mediators: Principal Effectors of Leiomyoma Development as a Fibrotic Disorder

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Diagnosis and management of eosinophilic asthma: a US perspective

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Pathogenic memory type Th2 cells in allergic inflammation

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Anti-IgE treatment, airway inflammation and remodelling in severe allergic asthma: current knowledge and future perspectives

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Lactobacillus paracasei feeding improves immune control of influenza infection in mice

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Innate lymphoid cells: critical regulators of allergic inflammation and tissue repair in the lung

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Interleukin-13–Induced Mucous Metaplasia Increases Susceptibility of Human Airway Epithelium to Rhinovirus Infection

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Dual Transcriptomic Profiling of Host and Microbiota during Health and Disease in Pediatric Asthma

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Adoptive Transfer of Induced-Treg Cells Effectively Attenuates Murine Airway Allergic Inflammation

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Interactions of airway epithelium with protease allergens in the allergic response

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Stem cells and lung regeneration

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Epigenetic regulation of T‐helper cell differentiation, memory, and plasticity in allergic asthma

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The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice

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Pulmonary vascular changes in asthma and COPD

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Brain‐derived neurotrophic factor induces proliferation of human airway smooth muscle cells

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Allergen-Induced Airway Remodeling Is Impaired in Galectin-3–Deficient Mice

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FOXM1 Promotes Allergen-Induced Goblet Cell Metaplasia and Pulmonary Inflammation

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Leptin Enhances TH2 and ILC2 Responses in Allergic Airway Disease

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Cell Cycle Arrest by Transforming Growth Factor β1 Enhances Replication of Respiratory Syncytial Virus in Lung Epithelial Cells

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The Role of Transforming Growth Factor-β (TGF-β) in Asthma and Chronic Obstructive Pulmonary Disease (COPD)

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Natural history of asthma: Persistence versus progression—does the beginning predict the end?

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Acute Severe Asthma in Adolescent and Adult Patients: Current Perspectives on Assessment and Management

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Biological Therapies of Severe Asthma and Their Possible Effects on Airway Remodeling

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Active ingredients from Chinese medicine plants as therapeutic strategies for asthma: Overview and challenges

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Developing a tissue-engineered model of the human bronchiole

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Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma

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PI3Kγ-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling

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Airway innate lymphoid cells in the induction and regulation of allergy

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DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma

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Review: Tissue remodeling and angiogenesis in asthma: the role of the eosinophil

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Leptin Promotes Allergic Airway Inflammation through Targeting the Unfolded Protein Response Pathway

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Anoctamin 1 in secretory epithelia

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The Other T Helper Cells in Asthma Pathogenesis

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Vitamin D as an adjunctive therapy in asthma. Part 1: A review of potential mechanisms

Kerley, C. P., Elnazir, B., Faul, J. L., & Cormican, L. J. (2015) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2015.02.004 · Cited by 54

MAPK Regulation of IL-4/IL-13 Receptors Contributes to the Synergistic Increase in CCL11/Eotaxin-1 in Response to TGF-β1 and IL-13 in Human Airway Fibroblasts

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Inhibition of airway remodeling and inflammatory response by Icariin in asthma

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Severe Persistent Allergic Rhinitis. Inflammation but No Histologic Features of Structural Upper Airway Remodeling

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Immunomodulatory role of oral microbiota in inflammatory diseases and allergic conditions

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Vitamin D Attenuates Cytokine‐Induced Remodeling in Human Fetal Airway Smooth Muscle Cells

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Pdcd4 modulates markers of macrophage alternative activation and airway remodeling in antigen-induced pulmonary inflammation

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Deficiency of Endothelial Heparan Sulfates Attenuates Allergic Airway Inflammation

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Th9: A New Player in Asthma Pathogenesis?

Xing, J., Wu, Y., & Ni, B. (2011) · Journal of Asthma · doi:10.3109/02770903.2011.554944 · Cited by 48

Long-Term Efficacy and Clinical Remission After Benralizumab Treatment in Patients with Severe Eosinophilic Asthma: A Retrospective Study

Numata, T., Araya, J., Okuda, K., Miyagawa, H., Minagawa, S., Ishikawa, T., Hara, H., & Kuwano, K. (2022) · Journal of Asthma and Allergy · doi:10.2147/jaa.s391807 · Cited by 46

Role of the coagulation system in allergic inflammation in the upper airways

Shimizu, S., Shimizu, T., Morser, J., Kobayashi, T., Yamaguchi, A., Qin, L., Toda, M., D’Alessandro‐Gabazza, C. N., Maruyama, T., Takagi, T., et al. (2008) · Clinical Immunology · doi:10.1016/j.clim.2008.07.020 · Cited by 46

Deregulated angiogenesis in chronic lung diseases: a possible role for lung mesenchymal progenitor cells (2017 Grover Conference Series)

Kropski, J. A., Richmond, B. W., Gaskill, C. F., Foronjy, R., & Majka, S. M. (2017) · Pulmonary Circulation · doi:10.1177/2045893217739807 · Cited by 43

Inflammatory Response Mechanisms Exacerbating Hypoxemia in Coexistent Pulmonary Fibrosis and Sleep Apnea

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Molecular changes during TGFβ-mediated lung fibroblast-myofibroblast differentiation: implication for glucocorticoid resistance

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Eosinophils in Fungus-Associated Allergic Pulmonary Disease

Ghosh, S., Hoselton, S. A., Dorsam, G. P., & Schuh, J. M. (2013) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00008 · Cited by 42

Effects of sustained stimulation with multi-wall carbon nanotubes on immune and inflammatory responses in mice

Yamaguchi, A., Fujitani, T., Ohyama, K.-I., Nakae, D., Hirose, A., Nishimura, T., & Ogata, A. (2012) · The Journal of Toxicological Sciences · doi:10.2131/jts.37.177 · Cited by 40

Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Regulates Hallmark Features of Airways Remodeling in Allergic Airways Disease

Collison, A., Li, J., de Siqueira, A. P., Zhang, J., Toop, H. D., Morris, J. C., Foster, P. S., & Mattes, J. E. (2014) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2013-0490oc · Cited by 40

IL-5 antagonism reverses priming and activation of eosinophils in severe eosinophilic asthma

Luo, J. F., Chen, W., Liu, W., Jiang, S., Ye, Y., Shrimanker, R., Hynes, G., Klenerman, P., Pavord, I. D., & Xue, L. (2024) · Mucosal Immunology · doi:10.1016/j.mucimm.2024.03.005 · Cited by 37

Beneficial effects of ursodeoxycholic acid via inhibition of airway remodelling, apoptosis of airway epithelial cells, and Th2 immune response in murine model of chronic asthma

Işık, S. R., Karaman, M., Mıçılı, S. Ç., Çağlayan-Sözmen, Ş., Bağrıyanık, A., Arıkan-Ayyıldız, Z., Uzuner, N., & Karaman, Ö. (2017) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2016.12.003 · Cited by 37

Cordycepin inhibits airway remodeling in a rat model of chronic asthma

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Role of vascular endothelial growth factor antagonism on airway remodeling in asthma

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Bioprinting stem cells: building physiological tissues one cell at a time

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Nasal and bronchial airway epithelial cell mediator release in children

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Mechanisms of BDNF regulation in asthmatic airway smooth muscle

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Systemic and exhaled cytokine and chemokine profiles are associated with the development of bronchiolitis obliterans syndrome

Kastelijn, E. A., Rijkers, G. T., van Moorsel, C. H. M., Zanen, P., Erp, J. M. K., van de Graaf, E. A., van Kessel, D. A., Grutters, J. C., & van den Bosch, J. M. M. (2010) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2010.04.013 · Cited by 33

l-2-Oxothiazolidine-4-Carboxylic Acid or α-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-κB (NF-κB), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF)

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A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatment

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