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Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ

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IKK-β links inflammation to obesity-induced insulin resistance

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Deletion of Rptor in Preosteoblasts Reveals a Role for the Mammalian Target of Rapamycin Complex 1 ( mTORC1) Complex in Dietary‐Induced Changes to Bone Mass and Glucose Homeostasis in Female Mice

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Change of Fibroblast Growth Factor 21 Level Correlates with the Severity of Diabetic Sensory Polyneuropathy after Six-Week Physical Activity

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Unsaturated oxidated fatty acid 12(S)-HETE attenuates TNF-α expression in TNF-α/IFN-γ-stimulated human keratinocytes

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Pathway‐based protein–protein association network to explore mechanism of α ‐glucosidase inhibitors from Scutellaria baicalensis Georgi against type 2 diabetes

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Dexamethasone ameliorates Alzheimer’s pathological condition via inhibiting Nf-κB and mTOR signaling pathways

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Metabolism toxicity and susceptibility of decabromodiphenyl ether (BDE-209) exposure on BRL cells with insulin resistance

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Construction of PIK3C3 Transgenic Pig and Its Pathogenesis of Liver Damage

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Molecular Liver Fingerprint Reflects the Seasonal Physiology of the Grey Mouse Lemur (Microcebus murinus) during Winter

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Comparative proteomic analysis of insulin receptor isoform A and B signaling

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The Role of Insulin Receptor Substrate Proteins in Bronchopulmonary Dysplasia and Asthma: New Potential Perspectives

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A novel recombinant peptide INSR-IgG4Fc (Yiminsu) restores insulin sensitivity in experimental insulin resistance models

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Corticosteroid-binding-globulin (CBG)-deficient mice show high pY216-GSK3β and phosphorylated-Tau levels in the hippocampus

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Supplementation of pyruvate prevents palmitate-induced impairment of glucose uptake in C2 myotubes

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IGF-1 mediated phosphorylation of specific IRS-1 serines inAmes dwarffibroblasts is associated with longevity

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Minor differences in the molecular machinery mediating regulated membrane fusion has major impact on metabolic health

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Exploring therapeutic targets in Toll-like receptor pathways: Implications for cardiovascular management in polycystic ovary syndrome

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Pharmacology of P2X Receptors and Their Possible Therapeutic Potential in Obesity and Diabetes

Cabral‐García, G. A., Cruz-Muñoz, J. R., Valdez-Moráles, E. E., Barajas‐Espinosa, A. R., Liñán-Rico, A., & Alba, R. G. (2024) · Pharmaceuticals · doi:10.3390/ph17101291 · Cited by 5

Epidermal Insulin Resistance as a Therapeutic Target in Acanthosis nigricans?

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Cell line cytotoxicity, antiadipogenic and glucose uptake activity of Sarcostemma brevistigma Wight. & Arn.

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Lack of association between the insulin receptor substrates-1 Gly972Arg polymorphism and type-2 diabetes mellitus among Saudis from Eastern Saudi Arabia

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Toolkit for Reverse Engineering of Molecular Pathways via Parameter Identification

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Research progress on the pathogenesis, clinical impact, and traditional Chinese medicine treatment of polycystic ovary syndrome complicated by insulin resistance

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Brain insulin resistance: a key pathological hub linking metabolic and neuropsychiatric comorbidities

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Caspase-1 Deficiency Modulates Adipogenesis through Atg7-Mediated Autophagy: An Inflammatory-Independent Mechanism

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Regulation of hepatic insulin sensitivity by activating signal co-integrator-2

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Involvement of receptor-interacting protein 140 in palmitate-stimulated macrophage infiltration of pancreatic beta cells

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Soluble CD14 inhibits contractile function and insulin action in primary adult rat cardiomyocytes

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Updated Insights into Probiotic Interventions for Metabolic Syndrome: Mechanisms and Evidence

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Profiles of serum amino acids to screen for catabolic and inflammation status in calves with Mycoplasma bronchopneumonia

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A Toolbox of Structural Biology and Enzyme Kinetics Reveals the Case for ERK Docking Site Inhibition

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Mechanism of TNFα-induced downregulation of salt-inducible kinase 2 in adipocytes

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Plasma Proteomic Signature in Overweight Girls Closely Correlates with Homeostasis Model Assessment (HOMA), an Objective Measure of Insulin Resistance

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Data-driven optimizations for model checking of multi-valued regulatory networks

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Native Fruits, Anthocyanins in Nutraceuticals, and the Insulin Receptor/Insulin Receptor Substrate-1/Akt/Forkhead Box Protein Pathway

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Metabolic Syndrome in Humans and Horses: The Relationship Between Obesity and Insulin Resistance

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Novel aspects of insulin resistance and type 2 diabetes mellitus: iron metabolism, the complement system, and liver cirrhosis

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Body composition markers are more strongly associated with type 2 diabetes than inflammatory markers—Results from the study of health in Pomerania

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System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells

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Targeting adipose remodeling: Synergistic mechanisms of drugs and adipose-derived stem cells in obese type 2 diabetes mellitus

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Dysregulation of the tryptophan-kynurenine pathway in type 2 diabetes: a systematic review and meta-analysis

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Models and Mechanisms of High-Fat Diet (HFD) Promotion of Pancreatic Cancer

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WITHDRAWN: RIP140 mediates hyperglycemia-induced glucotoxicity in β-cells via the activation of JNK and ERK1/2 signaling pathways

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The Gastric Connection: Serum Gastric Biomarkers, Metabolic Syndrome and Transition in Metabolic Status

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Linking Obesity and Pancreatic Cancer

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Conventional but not High-Purity Dialysis Fluid Induces Apoptosis and Insulin Resistance in Adipocytes in Vitro

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Lysine acetylsalicylate improves the safety of paraquat formulation in rats by increasing its elimination and preventing lung and kidney injury

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Insulin Signalling: Essential Role of a 222 Da Molecular Mediator, Co-Insulin (Co-Ins)

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Effect of curcumin on activation and expression of IRS1, Grb2, K-Ras and Bax in STZ-induced diabetic rat brains

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Prenatal Programming in the Fetus and Placenta

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Role of Inflammation in the Pathogenesis of Insulin Resistance in Obesity: Specific Role of Reactive Oxygen and Reactive Nitrogen Species

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Inflammatory Markers Among African American Adolescents with Type 2 Diabetes Mellitus and Obesity: A Cross-Sectional Study

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Development of Insulin and Leptin Resistance in the Mouse Brainstem with Age

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Dabrafenib and trametinib–induced hyperglycemia with decreased insulin secretion in a patient with lung adenocarcinoma

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Insulin resistance in the 21st century: new takes on an old problem—2025 Diabetes, Diabetes Care, and Diabetologia Expert Forum

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Implication des MAP kinases dans l’inflammation et l’insulino-résistance associées à l’obésité

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ERK1/2 MAP kinases: Structure, function, and regulation

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Profiles of serum amino acids to screen for catabolic and inflammation status in calves with mycoplasma bronchopneumonia

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Impact of Proinflammatory Cytokines on Adipocyte Insulin Signaling

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Phospholipase C in bacterial infections

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Inhalation exposure-induced toxicity and disease mediated via mTOR dysregulation

Shinde, A., & Shannahan, J. H. (2024) · Experimental Biology and Medicine · doi:10.3389/ebm.2024.10135 · Cited by 1

Deciphering the role of crucial miRNAs involved in diabetic cardiomyopathy through a multiomics approach

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Linking Inflammation, Obesity, and Diabetes

McArdle, M. A., Kennedy, E. B., & Roche, H. M. (2023) · Springer eBooks · doi:10.1007/978-3-031-40116-9_29 · Cited by 1

Molecular Mechanisms of AMPK- and Akt- Dependent Survival of Glucose-Starved Cardiac Myocytes

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MAP Kinase Modules in Signaling☆

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Biological mechanisms of aging predict age-related disease multimorbidities in patientsPreprint

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A suplementação crônica com beta hidroxi beta metilbutirato (HMB) reduz a sensibilidade à insulina de ratos de modo tecido-específico.

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Diabetogenic effects of Glucocorticoids : role of Protein Phosphatase 5 and GLP-1 receptor activation

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Serine/Threonine Protein Phosphatase 5 - a Double-edged Sword - in the Progression towards Diabetes

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Insulin signaling dynamics in human adipocytes : Mathematical modeling reveals mechanisms of insulin resistance in type 2 diabetes

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The Role of Systemic Inflammation in the Development of Equine Laminitis

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SENSORY NEURON INSULIN SIGNALING AND ITS ROLE IN DIABETIC NEUROPATHY

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Impact des cytokines pro-inflammatoires sur la signalisation insulinique de l’adipocyte

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Hepatocyte growth factor regulates inflammatory mediated diseases by suppression of IL-6: implications for type 2 diabetes

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Identification of in vivo interactions of insulin receptor substrate 1 in murine liver

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Insulin signaling dynamics in human adipocytes

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Crosstalk between adipocytes and immune cells in adipose tissue in an obese inflammatory state: role of contact-mediated signaling

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The effect of butter, naturally enriched with trans-10, cis-12 conjugated linoleic acid, on insulin resistance and inflammation in high fat-fed rodents

Stefanson, A. L. (2013) · The Atrium (University of Guelph)

Mechanisms of Insulin Resistance after Immunosuppressive Therapy in Brown Adipose Tissue

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AVALIAÇÃO DA ANEXINA A1, IL-6 E DE VIAS SINALIZADORAS INTRACELULARES NA OBESIDADE E NO DIABETES MELLITUS TIPO 2

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Activation of survival pathways triggered by death receptors in the nervous system

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Induction of insulin resistance by the adipokines resistin, leptin, PAI-1 and RBP4 in human megakaryocytes Running title: Adipokine-induced insulin-resistant megakaryocytes

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Rac GTPase Regulation of GLUT4 Traffic in Muscle Cells: Mechanisms and Implications

Chiu, T. T. (2014) · TSpace (University of Toronto)

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İNSÜLİN DİRENCİNDE İNSÜLİN RESEPTÖR SUBSTRAT 1 (IRS1) PROTEİNİNİN ROLÜ

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Exploring the Role of Insulin Receptor Signaling in Hippocampal Learning and Memory, Neuronal Calcium Dysregulation, and Glucose Metabolism

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A REVIEW ON HERBAL DRUG THERAPY FOR DIABETES MELLITUS

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Investigating the effects of carbohydrate or fatty acid treatment on lipid content in HepG2 human hepatocytes & mouse primary hepatocytes

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Hyperinsulinemia Induces Insulin Receptor Dysfunction in Brain Microvascular Endothelial CellsPreprint

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Linking Inflammation, Obesity, and Diabetes

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Linking Inflammation, Obesity and Diabetes

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Metabolism toxicity and susceptibility of decabromodiphenyl ether (BDE-209) exposure on BRL cells with insulin resistancePreprint

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