Cited by 231Virology and Viral DiseasesHIV Research and TreatmentCellular transport and secretion

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Cell-to-cell transmission of viruses

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Zhong, Peng, Agosto, Luis M, Munro, James B, Mothes, Walther·2013·Current Opinion in Virology

DOI 10.1016/j.coviro.2012.11.004PMC PMC3587356

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Abstract

The life cycle of most viruses involves the release of particles into the extracellular space. Consequently, the study of virus egress as well as virus entry has focused almost exclusively on the biology of cell-free virus. However, cell-free virus spread is often very inefficient. Specific barriers, either located in the donor cell or in the target cell, prevent efficient spread by the cell-free mode. In contrast, viral spread by direct cell-cell contact is largely unaffected by most of these barriers resulting in preferential spread by cell-to-cell transmission. Virus cell-to-cell transmission allows an efficient coordination of several steps of the viral life cycle. It often involves complex inter-cellular adhesion, cellular polarity and intra-cellular trafficking. Because virus cell-to-cell transmission can involve transmission through zones of tight cell-cell contact that are resistant to neutralizing antibodies and reach a high local particle concentration, cell-to-cell transmission can contribute to the pathogenesis of viral infections.

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Virus Entry: Open Sesame
Marsh, M., & Helenius, A. (2006) · Cell · doi:10.1016/j.cell.2006.02.007 · Cited by 1,209
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Igakura, T., Stinchcombe, J. C., Goon, P. K. C., Taylor, G. P., Weber, J. N., Griffiths, G. M., Tanaka, Y., Osame, M., & Bangham, C. R. M. (2003) · Science · doi:10.1126/science.1080115 · Cited by 755
Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission
Sowinski, S., Jolly, C., Berninghausen, O., Purbhoo, M. A., Chauveau, A., Köhler, K., Oddos, S., Eissmann, P., Brodsky, F. M., Hopkins, C., et al. (2008) · Nature Cell Biology · doi:10.1038/ncb1682 · Cited by 754
Recruitment of HIV and Its Receptors to Dendritic Cell-T Cell Junctions
McDonald, D., Wu, L., Bohks, S. M., KewalRamani, V. N., Unutmaz, D., & Hope, T. J. (2003) · Science · doi:10.1126/science.1084238 · Cited by 707
HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes
Miyauchi, K., Kim, Y., Latinovic, O., Va, M., & Melikyan, G. B. (2009) · Cell · doi:10.1016/j.cell.2009.02.046 · Cited by 682
Human Immunodeficiency Virus Type 1 Spinoculation Enhances Infection through Virus Binding
O’Doherty, U., Swiggard, W. J., & Malim, M. H. (2000) · Journal of Virology · doi:10.1128/jvi.74.21.10074-10080.2000 · Cited by 669
HIV-1 Cell to Cell Transfer across an Env-induced, Actin-dependent Synapse
Jolly, C., Kashefi, K., Hollinshead, M., & Sattentau, Q. J. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20030648 · Cited by 623
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Sattentau, Q. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1972 · Cited by 614
Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy
Sigal, A., Kim, J. T., Balazs, A. B., Dekel, E., Mayo, A., Milo, R., & Baltimore, D. (2011) · Nature · doi:10.1038/nature10347 · Cited by 538
Dissecting the Cell Entry Pathway of Dengue Virus by Single-Particle Tracking in Living Cells
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Show all 69 references

Research works printed but not linked: 1

Mazurov, 2011, The role of O-glycosylation and expression of CD43 and CD45 on the surface of effector T cells in HTLV-1 cell-to-cell infection, J Virol

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Authors: Zhong, P., Agosto, L. M., Munro, J. B., & Mothes, W.
Affiliations: Yale University (US)
Corresponding author: Mothes, Walther
ORCID: Agosto, Luis M
Munro, James B
Mothes, Walther
Venue: Current Opinion in Virology
Publisher: Elsevier BV
Published: 2013-02
Volume: 3
Issue: 1
Pages: 44-50
ISSN: 1879-6257 (ISSN-L)
DOI: 10.1016/j.coviro.2012.11.004
PMC: PMC3587356
OpenAlex: W1966635724
Cited by: 231
References: 69
Citations by year: 2026: 9 · 2025: 11 · 2024: 19 · 2023: 22 · 2022: 11 · 2021: 30 · 2020: 24 · 2019: 19 · 2018: 18 · 2017: 15 · 2016: 15 · 2015: 13 · 2014: 19 · 2013: 6
FWCI: 1.52
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Current Opinion in Virology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: Cancer Research Institute
Yale University
China Scholarship Council
National Institutes of Health
National Cancer Institute (R01CA098727)
National Institute of Allergy and Infectious Diseases (R01AI084096)
Topics: Health Sciences › Medicine › Epidemiology › Virology and Viral Diseases
Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular transport and secretion
Keywords: cell-to-cell transmission, viral egress, viral entry, viral life cycle, cell-cell adhesion, cell polarity, intracellular trafficking, neutralizing antibodies, viral pathogenesis, viral spread
MeSH terms: Animals, Cell Adhesion, HIV, Humans, Models, Biological, Vaccinia virus, Virus Internalization, Virus Release

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