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Short‐term, intermittent fasting induces long‐lasting gut health and TOR‐independent lifespan extension
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Tier 1 interventions such as exercise, fasting mimetics like metformin or rapamycin, fasting, and an epigenetic diet remain insufficient to slow down the damaging effects of aging.
“Tier 1 interventions such as staying fit, 1 , 2 taking pills such as fasting mimetics like metformin or rapamycin, 3 , 4 , 5 fasting, 3 , 6 , 7 and an epigenetic diet 8 remain insufficient to slow down the damaging effects of aging.”
From Three Tiers to biological escape velocity: The quest to outwit aging (2022) · cites this paper as [3]
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Time-restricted feeding attenuates age-related cardiac decline in Drosophila
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Martel, J., Chang, S.-H., Ko, Y.-F., Hwang, T.-L., Young, J. D., & Ojcius, D. M. (2022) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2022.01.002 · Cited by 514
Circadian autophagy drives iTRF-mediated longevity
Ulgherait, M., Midoun, A. M., Park, S. J., Gatto, J. A., Tener, S. J., Siewert, J., Klickstein, N., Canman, J. C., Ja, W. W., & Shirasu-Hiza, M. (2021) · Nature · doi:10.1038/s41586-021-03934-0 · Cited by 226
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Benjamin, D. I., Both, P., Benjamin, J. S., Nutter, C. W., Tan, J. H., Kang, J., Machado, L. A., Klein, J. D. D., de Morree, A., Kim, S., et al. (2022) · Cell Metabolism · doi:10.1016/j.cmet.2022.04.012 · Cited by 79
Three Tiers to biological escape velocity: The quest to outwit aging
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Metadata
- Authors
- Catterson, J. H., Khericha, M., Dyson, M. C., Vincent, A. J., Callard, R., Haveron, S. M., Rajasingam, A., Ahmad, M., & Partridge, L.
- Venue
- Current Biology
- Publisher
- Elsevier BV
- Published
- 2018-06
- Volume
- 28
- Issue
- 11
- Pages
- 1714-1724.e4
- ISSN
- 0960-9822
- PMC
- PMC5988561
- Cited by
- 152
- References
- 7
- Language
- en
- Licence
- Funders
- Wellcome Trust (098565)
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