CoChat
Sign Up
Cited by 25

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Neuroenergetics: Astrocytes Have a Sweet Spot for Glucose

Pellerin, Luc·2018·Current Biology
DOI 10.1016/j.cub.2018.09.042
Open this paper in CoChat — free account

Abstract

Astrocytes are polarized cells that are known to take up glucose while delivering lactate, not glucose, for neuronal use. A new study suggests how astrocytes could facilitate glucose uptake, storage and funneling at energy-requiring sites through a privileged intracellular route.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.cub.2018.09.042

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 17

  1. Pellerin, 1994, Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization, Proc. Natl. Acad. Sci. USA, 91, 10625, 10.1073/pnas.91.22.10625 · DOI · Paper page
  2. Voutsinos-Porche, 2003, Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex, Neuron, 37, 275, 10.1016/S0896-6273(02)01170-4 · DOI
  3. Zimmer, 2017, [18F]FDG PET signal is driven by astroglial glutamate transport, Nat. Neurosci., 20, 393, 10.1038/nn.4492 · DOI · Paper page
  4. Kacem, 1998, Structural organization of the perivascular astrocyte endfeet and their relationship with the endothelial glucose transporter: a confocal microscopy study, Glia, 23, 1, 10.1002/(SICI)1098-1136(199805)23:1<1::AID-GLIA1>3.0.CO;2-B · DOI
  5. Morgello, 1995, The human blood-brain barrier glucose transporter (GLUT1) is a glucose transporter of gray matter astrocytes, Glia, 14, 43, 10.1002/glia.440140107 · DOI
  6. Müller, 2018, Effective glucose uptake by human astrocytes requires its sequestration in the endoplasmic reticulum by glucose-6-phosphatase-β, Curr. Biol., 28, 3481, 10.1016/j.cub.2018.08.060 · DOI
  7. Waitt, 2017, Emerging roles for glycogen in the CNS, Front. Mol. Neurosci., 10, 73, 10.3389/fnmol.2017.00073 · DOI
  8. Schmidt, 1989, Refinement of the kinetic model of the 2-[14C]deoxyglucose method to incorporate effects of intracellular compartmentation in brain, J. Cereb. Blood Flow Metab., 9, 290, 10.1038/jcbfm.1989.47 · DOI
  9. Bindocci, 2017, Three-dimensional Ca2+ imaging advances understanding of astrocyte biology, Science, 356, 6339, 10.1126/science.aai8185 · DOI · Paper page
  10. Dringen, 1993, Glycogen in astrocytes: possible function as lactate supply for neighboring cells, Brain Res., 623, 208, 10.1016/0006-8993(93)91429-V · DOI
  11. Bittar, 1996, Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain, J. Cereb. Blood Flow Metab., 16, 1079, 10.1097/00004647-199611000-00001 · DOI · Paper page
  12. Pierre, 2005, Monocarboxylate transporters in the central nervous system: distribution, regulation and function, J. Neurochem., 94, 1, 10.1111/j.1471-4159.2005.03168.x · DOI · Paper page
  13. Sotelo-Hitschfeld, 2015, Channel-mediated lactate release by K+-stimulated astrocytes, J. Neurosci., 35, 4168, 10.1523/JNEUROSCI.5036-14.2015 · DOI
  14. Pellerin, 2012, Sweet sixteen for ANLS, J. Cereb. Blood Flow Metab., 32, 1152, 10.1038/jcbfm.2011.149 · DOI
  15. Bouzier-Sore, 2003, Lactate is a preferential oxidative energy substrate over glucose for neurons in culture, J. Cereb. Blood Flow Metab., 23, 1298, 10.1097/01.WCB.0000091761.61714.25 · DOI · Paper page
  16. Mächler, 2016, In vivo evidence for a lactate gradient from astrocytes to neurons, Cell Metab., 23, 94, 10.1016/j.cmet.2015.10.010 · DOI · Paper page
  17. Barros, 2013, Small is fast: astrocytic glucose and lactate metabolism at cellular resolution, Front. Cell. Neurosci., 7, 27, 10.3389/fncel.2013.00027 · DOI

Cited by

Sorted by citations

Metadata

Authors
Pellerin, L.
Venue
Current Biology
Publisher
Elsevier BV
Published
2018-11
Volume
28
Issue
21
Pages
R1258-R1260
ISSN
0960-9822
DOI
10.1016/j.cub.2018.09.042
Cited by
25
References
3
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review