The opportunities of mining historical and collective data in drug discovery

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Classification of scaffold-hopping approaches

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Applications of Connectivity Map in drug discovery and development

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An integrative biology approach for analysis of drug action in models of human vascular inflammation

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Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways

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Gene expression profiling in rat liver treated with compounds inducing phospholipidosis

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Formalization, Annotation and Analysis of Diverse Drug and Probe Screening Assay Datasets Using the BioAssay Ontology (BAO)

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Identification of a Kinase Profile that Predicts Chromosome Damage Induced by Small Molecule Kinase Inhibitors

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Compound Classification Using Image‐Based Cellular Phenotypes

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Analysis of Pfizer Compounds in EPA’s ToxCast Chemicals-Assay Space

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Scientific competency questions as the basis for semantically enriched open pharmacological space development

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Building Predictive Models for Mechanism-of-Action Classification from Phenotypic Assay Data Sets

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Predictive methods in drug repurposing: gold mine or just a bigger haystack?

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Composition and applications of focus libraries to phenotypic assays

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A Screening Pattern Recognition Method Finds New and Divergent Targets for Drugs and Natural Products

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Learning from ‘big data’: compounds and targets

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Benchmarking of Multivariate Similarity Measures for High-Content Screening Fingerprints in Phenotypic Drug Discovery

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Chemical Interrogation of the Neuronal Kinome Using a Primary Cell-Based Screening Assay

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Bioturbo Similarity Searching: Combining Chemical and Biological Similarity To Discover Structurally Diverse Bioactive Molecules

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Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors

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Identification of novel hair‐growth inducers by means of connectivity mapping

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An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines

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Pathway Reporter Assays Reveal Small Molecule Mechanisms of Action

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