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Cited by 509Substance Abuse Treatment and OutcomesTraffic and Road SafetyAlcohol Consumption and Health Effects

The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.

The more you drink, the harder you fall: A systematic review and meta-analysis of how acute alcohol consumption and injury or collision risk increase together

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Taylor, B., Irving, H.M., Kanteres, F., Room, R., Borges, G., Cherpitel, C., Greenfield, T., Rehm, J.·2010·Drug and Alcohol Dependence
DOI 10.1016/j.drugalcdep.2010.02.011PMC PMC2887748
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Abstract

Alcohol consumption causes injury in a dose-response manner. The most common mode of sustaining an alcohol-attributable injury is from a single occasion of acute alcohol consumption, but much of the injury literature employs usual consumption habits to assess risk instead. An analysis of the acute dose-response relationship between alcohol and injury is warranted to generate single occasion- and dose-specific relative risks. A systematic literature review and meta-analysis was conducted to fill this gap. Linear and best-fit first-order model were used to model the data. Usual tests of heterogeneity and publication bias were run. Separate meta-analyses were run for motor vehicle and non-motor vehicle injuries, as well as case-control and case-crossover studies. The risk of injury increases non-linearly with increasing alcohol consumption. For motor vehicle accidents, the odds ratio increases by 1.24 (95% CI: 1.18-1.31) per 10-g in pure alcohol increase to 52.0 (95% CI: 34.50-78.28) at 120 g. For non-motor vehicle injury, the OR increases by 1.30 (95% CI: 1.26-1.34) to an OR of 24.2 at 140 g (95% CI: 16.2-36.2). Case-crossover studies of non-MVA injury result in overall higher risks than case-control studies and the per-drink increase in odds of injury was highest for intentional injury, at 1.38 (95% CI: 1.22-1.55). Efforts to reduce drinking both on an individual level and a population level are important. No level of consumption is safe when driving and less than 2 drinks per occasion should be encouraged to reduce the risk of injury.

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Crossref · 10.1016/j.drugalcdep.2010.02.011

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  • The dose-response relationship between acute alcohol use, measured through the blood alcohol concentration and injury, seems exponential for all injury types, albeit varying slightly by type of injury.

    “The dose–response relationship between acute alcohol use, measured through the blood alcohol concentration and injury, seem exponential for all injury types, albeit varying slightly by type of injury 311, 312, 313.”

    From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [312]

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Research works printed but not linked: 1

  1. Rehm, 2004, Alcohol use, vol. 1, 959

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Metadata

Authors
Taylor, B., Irving, H. M., Kanteres, F., Room, R., Borges, G., Cherpitel, C., Greenfield, T., & Rehm, J.
Affiliations
  • Centre for Addiction and Mental Health (CA)
  • The University of Melbourne (AU)
  • World Health Organization (CH)
Corresponding author
Taylor, B.
ORCID
Venue
Drug and Alcohol Dependence
Publisher
Elsevier BV
Published
2010-07
Volume
110
Issue
1-2
Pages
108-116
ISSN
0376-8716 (ISSN-L)
DOI
10.1016/j.drugalcdep.2010.02.011
PMC
PMC2887748
OpenAlex
W2117662245
Cited by
509
References
64
Citations by year
2026: 27 · 2025: 30 · 2024: 24 · 2023: 29 · 2022: 32 · 2021: 31 · 2020: 27 · 2019: 25 · 2018: 43 · 2017: 40 · 2016: 43 · 2015: 37 · 2014: 32 · 2013: 35 · 2012: 27
FWCI
3.22
Type
journal article
Language
en
Open access
Licence
Locations
  • Drug and Alcohol Dependence (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Alcohol Abuse and Alcoholism (R01AA013750, P50AA005595)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Physical Sciences › Engineering › Safety, Risk, Reliability and Quality › Traffic and Road Safety
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Keywords
acute alcohol consumption, dose-response relationship, motor vehicle accidents, intentional injury, collision risk, alcohol and injury, alcohol guidelines
MeSH terms
Accidents, Traffic, Alcohol Drinking, Alcoholic Intoxication, Data Interpretation, Statistical, Dose-Response Relationship, Drug, Humans, Research Design, Risk, Wounds and Injuries, Odds Ratio, Case-Control Studies, Publication Bias, Cross-Over Studies

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