Effect of two counseling interventions on self-reported alcohol consumption, alcohol biomarker phosphatidylethanol (PEth), and viral suppression among persons living with HIV (PWH) with unhealthy alcohol use in Uganda: A randomized controlled trial
Open accessAbstract
PURPOSE: To test the efficacy of two interventions to reduce alcohol use and increase viral suppression compared to a control in persons with HIV (PWH). METHODS: In a three-arm (1:1:1) randomized controlled trial (N = 269), we compared in-person counselling (45-70 minutes, two sessions over three months) with interim monthly booster phone calls (live call arm) or twice-weekly automated booster sessions (technology arm) to a brief advice control arm. We enrolled PWH self-reporting unhealthy alcohol use (Alcohol Use Disorders Identification Test - Consumption, prior three months, women ≥3, men ≥4). Primary outcomes were number of self-reported drinking days (NDD) in the prior 21 and biomarker phosphatidylethanol (PEth) at six and nine months and viral suppression (<40 copies/mL) at nine months; we adjusted for sex and baseline outcomes. RESULTS: At baseline, mean 21-day NDDs were 9.4 (95 % CI: 9.1-9.8), mean PEth was 407.8 ng/mL (95 % CI: 340.7-474.8), and 89.2 % were virally suppressed. At follow-up, there were significant reductions in mean NDDs for the live call versus control arm (3.5, 95 % CI:2.1-4.9, p < 0.001) and for the technology versus control arm (3.6, 95 % CI: 2.2-5.1, p < 0.001). The mean PEth differences compared to the control arm were not significant, i.e. 36.4 ng/mL (95 % CI: -117.5 to 190.3, p = 0.643) for the live call and -30.9 ng/mL (95 % CI: -194.8 to 132.9, p = 0.711) for the technology arm. Nine-month viral suppression compared to the control was similar in the live call and in the technology arm. CONCLUSION: Intervention effects were found on self-reported NDD but not PEth or viral suppression, suggesting no treatment effect. (NCT #03928418).
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
A new scale of social desirability independent of psychopathology.
Crowne, D. P., & Marlowe, D. (1960) · Journal of Consulting Psychology · doi:10.1037/h0047358 · Cited by 8,686 · see citing works
An Empirical Evaluation of the System Usability Scale
Bangor, A., Kortum, P. T., & Miller, J. T. (2008) · International Journal of Human–Computer Interaction · doi:10.1080/10447310802205776 · Cited by 5,181 · see citing works
AUDIT‐C as a Brief Screen for Alcohol Misuse in Primary Care
Bradley, K. A., Rubinsky, A. D., Volk, R. J., Williams, E. C., Frank, D., & Kivlahan, D. R. (2007) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2007.00403.x · Cited by 1,634 · see citing works
Estimating log models: to transform or not to transform?
Manning, W. G., & Mullahy, J. (2001) · Journal of Health Economics · doi:10.1016/s0167-6296(01)00086-8 · Cited by 1,145 · see citing works
Morris, N. S., MacLean, C. D., Chew, L. D., & Littenberg, B. (2006) · BMC Family Practice · doi:10.1186/1471-2296-7-21 · Cited by 971 · see citing works
Mobile Text Messaging for Health: A Systematic Review of Reviews
Hall, A. K., Cole-Lewis, H., & Bernhardt, J. M. (2015) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031914-122855 · Cited by 815 · see citing works
Fleming, M. F. (1997) · JAMA · doi:10.1001/jama.1997.03540370029032 · Cited by 538 · see citing works
Reporting of Multi-Arm Parallel-Group Randomized Trials: Extension of the CONSORT 2010 Statement
Juszczak, E., Altman, D. G., Hopewell, S., & Schulz, K. (2019) · JAMA · doi:10.1001/jama.2019.3087 · Cited by 324 · cited 2× · see citing works
“gov (NCT #03928418) and followed the Consolidated Standards of Reporting Trials (CONSORT) reporting guideline for multi-arm parallel group trial designs (Juszczak et al., 2019).”
MethodWilliams, E. C., Hahn, J. A., Saitz, R., Bryant, K., Lira, M. C., & Samet, J. H. (2016) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.13204 · Cited by 294 · see citing works
Self-citationSankoh, O. A., Sevalie, S., & Weston, M. (2018) · The Lancet Global Health · doi:10.1016/s2214-109x(18)30303-6 · Cited by 216 · see citing works
Rubinsky, A. D., Dawson, D. A., Williams, E. C., Kivlahan, D. R., & Bradley, K. A. (2013) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12092 · Cited by 207 · see citing works
Ulwelling, W., & Smith, K. (2018) · Journal of Forensic Sciences · doi:10.1111/1556-4029.13874 · Cited by 199 · see citing works
The UCSF Client Satisfaction Scales: I. The Client Satisfaction Questionnaire-8.
Attkisson, C. C., & Greenfield, T. K. (1999) · Cited by 178 · see citing works
Gnann, H., Weinmann, W., & Thierauf, A. (2012) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2012.01768.x · Cited by 159 · see citing works
Rethinking brief interventions for alcohol in general practice
McCambridge, J., & Saitz, R. (2017) · BMJ · doi:10.1136/bmj.j116 · Cited by 146 · see citing works
Adding Fuel to the Fire: Alcohol’s Effect on the HIV Epidemic in Sub-Saharan Africa
Hahn, J. A., Woolf‐King, S. E., & Muyindike, W. R. (2011) · Current HIV/AIDS Reports · doi:10.1007/s11904-011-0088-2 · Cited by 136 · see citing works
Self-citationThe MASH Research Team, Scott-Sheldon, L. A. J., Carey, K. B., Johnson, B. T., & Carey, M. P. (2017) · AIDS and Behavior · doi:10.1007/s10461-017-1886-3 · Cited by 133 · see citing works
Luginbühl, M., Wurst, F. M., Stöth, F., et al. (2022) · Drug Testing and Analysis · doi:10.1002/dta.3340 · Cited by 129 · see citing works
Hahn, J. A., Dobkin, L. M., Mayanja, B., Emenyonu, N. I., Kigozi, I., Shiboski, S. C., Bangsberg, D. R., Gnann, H., Weinmann, W., & Wurst, F. M. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01669.x · Cited by 127 · see citing works
Self-citationSingla, D. R., Weobong, B., Nadkarni, A., Chowdhary, N., Shinde, S., Anand, A., Fairburn, C. G., Dimijdan, S., Velleman, R. D. B., Weiss, H. A., et al. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.06.006 · Cited by 123 · see citing works
The detection of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol in human dried blood spots
Jones, J., Jones, M., Plate, C. A., & Lewis, D. (2011) · Analytical Methods · doi:10.1039/c0ay00636j · Cited by 116 · see citing works
Hahn, J. A., Emenyonu, N. I., Fatch, R., Muyindike, W. R., Kekiibina, A., Carrico, A. W., Woolf‐King, S., & Shiboski, S. (2016) · Addiction · doi:10.1111/add.13173 · Cited by 97 · see citing works
Self-citationHahn, J. A., Anton, R. F., & Javors, M. A. (2016) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13213 · Cited by 93 · see citing works
Self-citationRecommended Use of Terminology in Addiction Medicine
Saitz, R., Miller, S. C., Fiellin, D. A., & Rosenthal, R. N. (2020) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000673 · Cited by 92 · see citing works
Hahn, J. A., Murnane, P. M., Vittinghoff, E., Muyindike, W. R., Emenyonu, N. I., Fatch, R., Chamie, G., Haberer, J. E., Francis, J. M., Kapiga, S., et al. (2021) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.14611 · Cited by 87 · see citing works
Self-citationChander, G., Hutton, H. E., Lau, B., Xu, X., & McCaul, M. E. (2015) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000679 · Cited by 83 · see citing works
Self-citationMagidson, J. F., Joska, J. A., Belus, J. M., Andersen, L. S., Regenauer, K. S., Rose, A. L., Myers, B., Majokweni, S., O’Cleirigh, C., & Safren, S. A. (2021) · Journal of the International AIDS Society · doi:10.1002/jia2.25720 · Cited by 82 · see citing works
A cautionary note regarding count models of alcohol consumption in randomized controlled trials
Horton, N. J., Kim, E., & Saitz, R. (2007) · BMC Medical Research Methodology · doi:10.1186/1471-2288-7-9 · Cited by 72 · see citing works
Wandera, B., Tumwesigye, N. M., Nankabirwa, J. I., Mafigiri, D. K., Parkes-Ratanshi, R. M., Kapiga, S., Hahn, J., & Sethi, A. K. (2017) · Journal of the International Association of Providers of AIDS Care (JIAPAC) · doi:10.1177/2325957416649669 · Cited by 61 · see citing works
Self-citationLecher, S. L., Fonjungo, P. N., Ellenberger, D. L., Adjé-Touré, C., Alemnji, G. A., Bowen, N., Basiye, F. L., Beukes, A., Carmona, S., de Klerk, M., et al. (2021) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm7021a2 · Cited by 61 · see citing works
Madhombiro, M., Musekiwa, A., January, J., Chingono, A., Abas, M., & Seedat, S. (2019) · Systematic Reviews · doi:10.1186/s13643-019-1176-4 · Cited by 57 · see citing works
Social Desirability Bias Impacts Self‐Reported Alcohol Use Among Persons With HIV in Uganda
Adong, J., Fatch, R., Emenyonu, N. I., Cheng, D. M., Muyindike, W. R., Ngabirano, C., Kekibiina, A., Woolf‐King, S. E., Samet, J. H., & Hahn, J. A. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14218 · Cited by 50 · see citing works
Self-citationMadhombiro, M., Kidd, M., Dube, B., Dube, M., Mutsvuke, W., Muronzie, T., Zhou, D. T., Derveeuw, S., Chibanda, D., Chingono, A., et al. (2020) · Journal of the International AIDS Society · doi:10.1002/jia2.25641 · Cited by 49 · see citing works
Kane, J. C., Sharma, A., Murray, L. K., Chander, G., Kanguya, T., Skavenski, S., Chitambi, C., Lasater, M. E., Paul, R., Cropsey, K., et al. (2022) · AIDS and Behavior · doi:10.1007/s10461-021-03408-4 · Cited by 49 · see citing works
Self-citationPapas, R. K., Gakinya, B. N., Mwaniki, M. M., Keter, A., Lee, H., Loxley, M. P., Klein, D. A., Sidle, J. E., Martino, S., Baliddawa, J. B., et al. (2016) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13132 · Cited by 47 · see citing works
Muyindike, W. R., Lloyd-Travaglini, C. A., Fatch, R., Emenyonu, N. I., Adong, J., Ngabirano, C., Cheng, D. M., Winter, M. R., Samet, J. H., & Hahn, J. A. (2017) · AIDS Care · doi:10.1080/09540121.2017.1290209 · Cited by 44 · see citing works
Self-citationGo, V. F.-L., Hutton, H. E., Hà, T. V., Chander, G., Latkin, C. A., Mai, N. V. T., Quynh, B. X., Nguyen, V. Q. C., Sripaipan, T., Lancaster, K. E., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.17115 · Cited by 41 · see citing works
Self-citationthe META team, Magidson, J. F., Fatch, R., Orrell, C., Amanyire, G., Haberer, J. E., & Hahn, J. A. (2018) · AIDS and Behavior · doi:10.1007/s10461-018-2364-2 · Cited by 39 · see citing works
Self-citationPapas, R. K., Gakinya, B. N., Mwaniki, M. M., Lee, H., Keter, A. K., Martino, S., Klein, D. A., Liu, T., Loxley, M. P., Sidle, J. E., et al. (2021) · Addiction · doi:10.1111/add.15112 · Cited by 37 · see citing works
Huis in ‘t Veld, D., Ensoy-Musoro, C., Pengpid, S., Peltzer, K., & Colebunders, R. (2019) · PLOS ONE · doi:10.1371/journal.pone.0220799 · Cited by 35 · see citing works
Pantalon, M. V., Martino, S., Dziura, J., Li, F.-Y., Owens, P. H., Fiellin, D. A., O'Connor, P. G., & D'Onofrio, G. (2012) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2012.08.011 · Cited by 30 · see citing works
Rubin, M. (2017) · doi:10.31234/osf.io/m2jgn · Cited by 29 · see citing works
Francis, J. M., Cook, S., Morojele, N. K., & Swahn, M. H. (2020) · Journal of Substance Use · doi:10.1080/14659891.2019.1664662 · Cited by 26 · cited 13× · see citing works
“Phosphatidylethanol (PEth) as a biomarker of alcohol consumption in HIV-positive patients in sub-Saharan Africa.”
BackgroundInfluentialSatre, D. D., Sarovar, V., Leyden, W. A., Hare, C. B., Catz, S. L., BRYANT, K. J., Williams, E. C., Hojilla, J. C., Horberg, M. A., & Silverberg, M. J. (2019) · AIDS and Behavior · doi:10.1007/s10461-019-02742-y · Cited by 21 · see citing works
Leddy, A. M., Hahn, J. A., Getahun, M., Emenyonu, N. I., Woolf‐King, S. E., Sanyu, N., Katusiime, A., Fatch, R., Chander, G., Hutton, H. E., et al. (2021) · AIDS and Behavior · doi:10.1007/s10461-021-03186-z · Cited by 13 · see citing works
Self-citationAsiimwe, C., Fatch, R., Cheng, D. M., Emenyonu, N. I., Ngabirano, C., Muyindike, W. R., & Hahn, J. A. (2022) · AIDS and Behavior · doi:10.1007/s10461-022-03934-9 · Cited by 12 · see citing works
Self-citationMcGinnis, K. A., Tate, J. P., BRYANT, K. J., Justice, A. C., O’Connor, P. G., Rodriguez‐Barradas, M. C., Crystal, S., Cutter, C. J., Hansen, N. B., Maisto, S. A., et al. (2021) · AIDS and Behavior · doi:10.1007/s10461-021-03438-y · Cited by 10 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Sobell LC, Sobell MB, 1992. Timeline follow-back: a technique for assessing self-reported ethanol consumption. In: Allen J, Litten RZ (Eds.), Measuring Alcohol Consumption: Psychosocial and Biological Methods. Humana Press, Totowa, NJ.
Cited by
Sorted by citations
A scoping review of substance use brief interventions in Africa
Jaguga, F., Kiburi, S. K., Temet, E., Aalsma, M. C., Ott, M. A., Maina, R. W., Wachira, J., Mostert, C., Kosgei, G., Tenge, A., et al. (2024) · PLOS Global Public Health · doi:10.1371/journal.pgph.0003340 · Cited by 10 · see citing works
Hahn, J. A., Kevany, S., Emenyonu, N. I., Sanyu, N., Katusiime, A., Muyindike, W. R., Fatch, R., & Shade, S. B. (2023) · AIDS and Behavior · doi:10.1007/s10461-023-04010-6 · Cited by 4 · see citing works
Self-citationKahler, C. W., Surace, A., Liu, T., Pantalone, D. W., Mastroleo, N. R., Yan, Y., Wray, T. B., Mayer, K. H., & Monti, P. M. (2024) · AIDS and Behavior · doi:10.1007/s10461-024-04493-x · Cited by 4 · see citing works
Gichane, M. W., Camlin, C. S., Getahun, M., Emenyonu, N., Woolf-King, S., Sanyu, N., Katusiime, A., Fatch, R., Muyindike, W., & Hahn, J. A. (2023) · Substance Use & Misuse · doi:10.1080/10826084.2023.2244066 · Cited by 1 · see citing works
Self-citation
- Authors
- Hahn, J. A., Fatch, R., Emenyonu, N. I., Sanyu, N., Katusiime, A., Levine, B., John Boscardin, W., Chander, G., Hutton, H., Camlin, C. S., Woolf-King, S. E., & Muyindike, W. R.
- Affiliations
- University of California, San Francisco (US)
- Mbarara University of Science and Technology (UG)
- San Francisco State University (US)
- University of Washington (US)
- Johns Hopkins University (US)
- Corresponding author
- Hahn, Judith A.
- ORCID
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 2023-03
- Volume
- 244
- Pages
- 109783
- ISSN
- 0376-8716 (ISSN-L)
- PMC
- PMC10437504
- OpenAlex
- W4317666141
- Cited by
- 22
- References
- 47
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 11 · 2023: 4
- FWCI
- 4.37
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Drug and Alcohol Dependence (publishedVersion, cc-by)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion, cc-by)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- Funders
- National Institutes of Health
- National Institute on Alcohol Abuse and Alcoholism (R01 AA024990, K24 AA022586)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- people living with HIV, alcohol consumption, alcohol counseling, viral suppression, phosphatidylethanol, alcohol biomarkers, in-person counseling, Uganda, HIV prevention and treatment services, brief advice, treatment effect heterogeneity, women living with HIV, HIV-positive men
- MeSH terms
- Alcohol Drinking, Ethanol, Alcoholism, Counseling, Female, Humans, Male, Uganda, Biomarkers, HIV Infections, Glycerophospholipids, Self Report
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
