Epidemiological perspectives on PFAS: Environmental fate, health risks, and global mitigation strategies

Perfluoroalkyl and polyfluoroalkyl substances in the environment: Terminology, classification, and origins

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Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

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Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers

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The Developmental Toxicity of Perfluoroalkyl Acids and Their Derivatives

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Fate and Effects of Poly- and Perfluoroalkyl Substances in the Aquatic Environment: A Review

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Half-Lives of PFOS, PFHxS and PFOA after End of Exposure to Contaminated Drinking Water

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Serum Vaccine Antibody Concentrations in Children Exposed to Perfluorinated Compounds

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Polyfluoroalkyl compounds in the aquatic environment: a review of their occurrence and fate

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Perfluorinated Chemicals and Fetal Growth: A Study within the Danish National Birth Cohort

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Comparing the toxic potency in vivo of long-chain perfluoroalkyl acids and fluorinated alternatives

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Exposure to per- and polyfluoroalkyl substances and markers of liver injury: a systematic review and meta-analysis

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Carcinogenicity of Perfluorooctanoic Acid and Perfluorooctanesulfonic Acid

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Distribution and sources of polyfluoroalkyl substances (PFAS) in the River Rhine watershed

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Perfluoroalkyl substances (PFAS) in surface water and sediments from two urban watersheds in Nevada, USA

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Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein

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Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease

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Neonatal Exposure to PFOS and PFOA in Mice Results in Changes in Proteins which are Important for Neuronal Growth and Synaptogenesis in the Developing Brain

Johansson, N., Eriksson, P., & Viberg, H. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfp029 · Cited by 284 · see citing works

Perfluoroalkyl and polyfluoroalkyl substances and human fetal growth: A systematic review

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Novel Chlorinated Polyfluorinated Ether Sulfonates and Legacy Per-/Polyfluoroalkyl Substances: Placental Transfer and Relationship with Serum Albumin and Glomerular Filtration Rate

Pan, Y., Zhu, Y., Zheng, T., Cui, Q., Buka, S. L., Zhang, B., Guo, Y., Xia, W., Yeung, L. W. Y., Li, Y., et al. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.6b04590 · Cited by 259 · see citing works

Elevated Levels of Ultrashort- and Short-Chain Perfluoroalkyl Acids in US Homes and People

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Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome

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Estimated exposures to perfluorinated compounds in infancy predict attenuated vaccine antibody concentrations at age 5-years

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Perfluoroalkyl substances and severity of nonalcoholic fatty liver in Children: An untargeted metabolomics approach

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Serum Vaccine Antibody Concentrations in Adolescents Exposed to Perfluorinated Compounds

Grandjean, P., Heilmann, C. J., Weihe, P., Nielsen, F., Mogensen, U. B., & Budtz–Jørgensen, E. (2016) · Environmental Health Perspectives · doi:10.1289/ehp275 · Cited by 208 · see citing works

PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men

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Early-life exposure to persistent organic pollutants (OCPs, PBDEs, PCBs, PFASs) and attention-deficit/hyperactivity disorder: A multi-pollutant analysis of a Norwegian birth cohort

Lenters, V. C., Iszatt, N., Forns, J., Čechová, E., Kočan, A., Legler, J., Leonards, P. E. G., Stigum, H., & Eggesbø, M. Å. (2019) · Environment International · doi:10.1016/j.envint.2019.01.020 · Cited by 194 · see citing works

Distribution, partitioning behavior and positive matrix factorization-based source analysis of legacy and emerging polyfluorinated alkyl substances in the dissolved phase, surface sediment and suspended particulate matter around coastal areas of Bohai Bay, China

Liu, Y., Zhang, Y., Li, J., Wu, N., Li, W., & Niu, Z. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2018.11.113 · Cited by 191 · see citing works

Crop bioaccumulation and human exposure of perfluoroalkyl acids through multi-media transport from a mega fluorochemical industrial park, China

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Reproductive toxicity of PFOA, PFOS and their substitutes: A review based on epidemiological and toxicological evidence

Shi, W., Zhang, Z., Li, M., Dong, H., & Li, J. (2024) · Environmental Research · doi:10.1016/j.envres.2024.118485 · Cited by 183 · see citing works

Prediction of Aqueous Solubility, Vapor Pressure and Critical Micelle Concentration for Aquatic Partitioning of Perfluorinated Chemicals

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Adverse Maternal, Fetal, and Postnatal Effects of Hexafluoropropylene Oxide Dimer Acid (GenX) from Oral Gestational Exposure in Sprague-Dawley Rats

Conley, J. M., Lambright, C. S., Evans, N., Strynar, M. J., McCord, J. P., Mcintyre, B., Travlos, G. S., Cardon, M. C., Medlock-Kakaley, E., Hartig, P. C., et al. (2019) · Environmental Health Perspectives · doi:10.1289/ehp4372 · Cited by 170 · see citing works

Fetal growth indicators and perfluorinated chemicals: a study in the Danish National Birth Cohort.

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Prenatal Exposure to Perfluoroalkyl Substances Associated With Increased Susceptibility to Liver Injury in Children

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A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior

Starnes, H. M., Rock, K. D., Jackson, T. W., & Belcher, S. M. (2022) · Frontiers in Toxicology · doi:10.3389/ftox.2022.881584 · Cited by 166 · see citing works

Urban versus Remote Air Concentrations of Fluorotelomer Alcohols and Other Polyfluorinated Alkyl Substances in Germany

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Elevated Levels of Per- and Polyfluoroalkyl Substances in Cape Fear River Striped Bass (Morone saxatilis) Are Associated with Biomarkers of Altered Immune and Liver Function

Guillette, T. C., McCord, J., Guillette, M., Polera, M. E., Rachels, K. T., Morgeson, C., Kotlarz, N., Knappe, D. R. U., Reading, B. J., Strynar, M., et al. (2020) · Environment International · doi:10.1016/j.envint.2019.105358 · Cited by 164 · see citing works

Legacy and emerging per-and polyfluoroalkyl substances (PFAS) in the Bohai Sea and its inflow rivers

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Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort

Liew, Z., Ritz, B. R., Ehrenstein, O. S. V., Bech, B. H., Nohr, E. A., Fei, C., Bossi, R., Henriksen, T. B., Bonefeld‐Jørgensen, E. C., & Olsen, J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1408412 · Cited by 149 · see citing works

Occurrence and distribution of conventional and new classes of per- and polyfluoroalkyl substances (PFASs) in the South China Sea

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Profiles of Emerging and Legacy Per-/Polyfluoroalkyl Substances in Matched Serum and Semen Samples: New Implications for Human Semen Quality

Pan, Y., Cui, Q., Wang, J., Sheng, N., Jing, J., Yao, B., & Dai, J. (2019) · Environmental Health Perspectives · doi:10.1289/ehp4431 · Cited by 141 · see citing works

Endocrine Disruptor Potential of Short- and Long-Chain Perfluoroalkyl Substances (PFASs)—A Synthesis of Current Knowledge with Proposal of Molecular Mechanism

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Spatiotemporal distribution, partitioning behavior and flux of per- and polyfluoroalkyl substances in surface water and sediment from Poyang Lake, China

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Global distribution potential and regional environmental risk of F-53B

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Chronic Exposure of Female Mice to an Environmental Level of Perfluorooctane Sulfonate Suppresses Estrogen Synthesis Through Reduced Histone H3K14 Acetylation of the StAR Promoter Leading to Deficits in Follicular Development and Ovulation

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Maternal levels of perfluoroalkyl substances (PFASs) during pregnancy and childhood allergy and asthma related outcomes and infections in the Norwegian Mother and Child (MoBa) cohort

Impinen, A., Longnecker, M. P., Nygaard, U. C., London, S. J., Ferguson, K. K., Haug, L. S., & Granum, B. B. (2019) · Environment International · doi:10.1016/j.envint.2018.12.041 · Cited by 108 · see citing works

Evidences for replacing legacy per- and polyfluoroalkyl substances with emerging ones in Fen and Wei River basins in central and western China

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Perfluorooctanoic acid disrupts the blood–testis barrier and activates the TNFα/p38 MAPK signaling pathway in vivo and in vitro

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Prenatal exposure to perfluoroalkyl acids and prevalence of infectious diseases up to 4 years of age

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Possible Mechanism of Perfluorooctane Sulfonate and Perfluorooctanoate on the Release of Calcium Ion from Calcium Stores in Primary Cultures of Rat Hippocampal Neurons

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Exposure to perfluoroalkyl substances during fetal life and hospitalization for infectious disease in childhood: A study among 1,503 children from the Odense Child Cohort

Dalsager, L., Christensen, N., Halekoh, U., Timmermann, C. A. G., Nielsen, F., Kyhl, H. B., Husby, S., Grandjean, P., Jensen, T. K., & Andersen, H. R. (2021) · Environment International · doi:10.1016/j.envint.2021.106395 · Cited by 90 · see citing works

Fate, distribution, and contrasting temporal trends of perfluoroalkyl substances (PFASs) in Lake Ontario, Canada

Myers, A. L., Crozier, P. W., Helm, P. A., Brimacombe, C., Furdui, V. I., Reiner, E. J., Burniston, D., & Marvin, C. H. (2012) · Environment International · doi:10.1016/j.envint.2012.02.002 · Cited by 87 · see citing works

Structural equation modeling of immunotoxicity associated with exposure to perfluorinated alkylates

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Syndecan-2 in colorectal cancer plays oncogenic role via epithelial-mesenchymal transition and MAPK pathway

Hua, R., Yu, J., Yan, X., Ni, Q., Zhi, X., Li, X., Jiang, B., & Zhu, J. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109630 · Cited by 86 · see citing works

Early life exposure to per- and polyfluoroalkyl substances and mid-childhood lipid and alanine aminotransferase levels

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Short-chain PFASs dominance and their environmental transport dynamics in urban water systems: Insights from multimedia transport analysis and human exposure risk

Zhang, K., Qadeer, A., Chang, S., Tu, X., Shang, H., Khan, M. A., Zhu, Y., Fu, Q., Yu, Y., & Feng, Y. (2025) · Environment International · doi:10.1016/j.envint.2025.109602 · Cited by 78 · see citing works

Legacy and alternative per- and polyfluoroalkyl substances (PFASs) in the West River and North River, south China: Occurrence, fate, spatio-temporal variations and potential sources

Chen, C.-E., Yang, Y., Zhao, J., Liu, Y., Hu, L., Li, B., Li, C.-L., & Ying, G. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2021.131301 · Cited by 75 · see citing works

Maternal exposure to perfluorooctanoic acid inhibits luteal function via oxidative stress and apoptosis in pregnant mice

Chen, Y., Zhou, L., Xu, J., Zhang, L., Li, M., Xie, X., Xie, Y., Luo, D., Zhang, D., Yu, X., et al. (2017) · Reproductive Toxicology · doi:10.1016/j.reprotox.2017.02.010 · Cited by 74 · see citing works

Altered expression and activity of phase I and II biotransformation enzymes in human liver cells by perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS)

Franco, M. E., Sutherland, G. E., Fernández-Luna, M. T., & Lavado, R. (2019) · Toxicology · doi:10.1016/j.tox.2019.152339 · Cited by 73 · see citing works

Impact of perfluoroalkyl substances (PFAS) and PFAS mixtures on lipid metabolism in differentiated HepaRG cells as a model for human hepatocytes

Sadrabadi, F., Alarcan, J., Sprenger, H., Braeuning, A., & Buhrke, T. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03649-3 · Cited by 73 · see citing works

Effects of in Utero PFOS Exposure on Transcriptome, Lipidome, and Function of Mouse Testis

Lai, K. P., Lee, J. C., Wan, H. T., Li, J., Wong, A. Y.-M., Chan, T., Oger, C., Galano, J., Durand, T., Leung, K. S., et al. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b02102 · Cited by 72 · see citing works

Airborne Perfluorooctanoate May Be a Substantial Source Contamination in Kyoto Area, Japan

Harada, K., Nakanishi, S., Saito, N., Tsutsui, T., & Koizumi, A. (2005) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/s00128-004-0548-0 · Cited by 72 · see citing works

PFOS facilitates liver inflammation and steatosis: An involvement of NLRP3 inflammasome‐mediated hepatocyte pyroptosis

Qin, Y., Gu, T., Ling, J., Luo, J., Zhao, J., Hu, B., Hua, L., Wan, C., & Jiang, S. (2021) · Journal of Applied Toxicology · doi:10.1002/jat.4258 · Cited by 70 · see citing works

Propranolol Suppresses the Growth of Colorectal Cancer Through Simultaneously Activating Autologous CD8 + T Cells and Inhibiting Tumor AKT/MAPK Pathway

Liao, P., Song, K., Zhu, Z., Liu, Z., Zhang, W., Li, W., Hu, J., Hu, Q., Chen, C., Chen, B., et al. (2020) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1894 · Cited by 67 · see citing works

Perfluorooctane sulfonate (PFOS) disrupts testosterone biosynthesis via CREB/CRTC2/StAR signaling pathway in Leydig cells

Qiu, L., Wang, H., Dong, T., Huang, J., Li, T., Ren, H., Wang, X., Qu, J., & Wang, S. (2020) · Toxicology · doi:10.1016/j.tox.2020.152663 · Cited by 66 · see citing works

Increased perfluorooctanoic acid accumulation facilitates the migration and invasion of lung cancer cells via remodeling cell mechanics

Mei, J., Jiang, J., Zhao, L., Pan, Y., Xu, K., Gao, X., Yuan, J., Li, L., Wang, Y., Wang, L., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2408575121 · Cited by 65 · see citing works

Prenatal Maternal Serum Concentrations of Per- and Polyfluoroalkyl Substances in Association with Autism Spectrum Disorder and Intellectual Disability

Lyall, K., Yau, V. M., Hansen, R. L., Kharrazi, M., Yoshida, C. K., Calafat, A. M., Windham, G. C., & Croen, L. (2018) · Environmental Health Perspectives · doi:10.1289/ehp1830 · Cited by 62 · see citing works

Perfluoroalkyl Substances Promote Breast Cancer Progression Via Erα and Gper Mediated Pi3k/Akt and Mapk/Erk Signaling Pathways

Liu, Q., Liu, Y., Li, X., Wang, D., Zhang, A., Pang, J., He, J., Chen, X., & Tang, N. (2022) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114980 · Cited by 62 · see citing works

Selective delivery of curcumin to breast cancer cells by self-targeting apoferritin nanocages with pH-responsive and low toxicity

Ji, P., Wang, X., Yin, J., Mou, Y., Huang, H., & Ren, Z. (2022) · Drug Delivery · doi:10.1080/10717544.2022.2056662 · Cited by 59 · see citing works

Perfluoroalkyl substances measured in breast milk and child neuropsychological development in a Norwegian birth cohort study.

Forns, J., Iszatt, N., White, R., Mandal, S., Sabaredzovic, A., Lamoree, M., Thomsen, C., Haug, L., Stigum, H., & Eggesbø, M. (2015) · Environment International · doi:10.1016/j.envint.2015.06.013 · Cited by 54 · see citing works

Neurotoxic effects of per- and polyfluoroalkyl substances (PFAS) mixture exposure in mice: Accumulations in brain and associated changes of behaviors, metabolome, and transcriptome

He, Q., Yang, Q., Wu, L., He, Y., Zeng, N., & Wang, Z. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.137699 · Cited by 53 · see citing works

The Extent of the Impact of a Fluorochemical Industrial Park in Eastern China on Adjacent Rural Areas

Lu, G.-H., Jiao, X. C., Piao, H.-T., Wang, X., Chen, S., Tan, K.-Y., Gai, N., Yin, X., Yang, Y., & Pan, J. (2017) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-017-0458-x · Cited by 51 · see citing works

Childhood perfluoroalkyl substance exposure and executive function in children at 8 years

Vuong, A. M., Yolton, K. A., Wang, Z., Xie, C., Webster, G. M., Ye, X., Calafat, A. M., Braun, J. M., Dietrich, K. N., Lanphear, B. P., et al. (2018) · Environment International · doi:10.1016/j.envint.2018.06.028 · Cited by 50 · see citing works

Perfluorooctanesulfonate induces neuroinflammation through the secretion of TNF-α mediated by the JAK2/STAT3 pathway

Chen, X., Nie, X., Mao, J., Zhang, Y., Yin, K., & Jiang, S. (2018) · NeuroToxicology · doi:10.1016/j.neuro.2018.03.003 · Cited by 48 · see citing works

Prenatal and childhood perfluoroalkyl substances exposures and children's reading skills at ages 5 and 8 years

Zhang, H., Yolton, K. A., Webster, G. M., Ye, X., Calafat, A. M., Dietrich, K. N., Xu, Y. Y., Xie, C., Braun, J. M., Lanphear, B. P., et al. (2017) · Environment International · doi:10.1016/j.envint.2017.11.031 · Cited by 47 · see citing works

RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression

Han, H., Lin, T., Wang, Z., Song, J., Fang, Z., Zhang, J., You, X., Du, Y., Ye, J., & Zhou, G. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106593 · Cited by 46 · see citing works

Per- and polyfluoroalkyl substances and male reproductive health: a systematic review of the epidemiological evidence

Petersen, K. U., Larsen, J., Deen, L., Flachs, E. M., Hærvig, K. K., Hull, S. D., Bonde, J. P., & Tøttenborg, S. S. (2020) · Journal of Toxicology and Environmental Health Part B · doi:10.1080/10937404.2020.1798315 · Cited by 45 · see citing works

Secondary bile acids improve risk prediction for non‐invasive identification of mild liver fibrosis in nonalcoholic fatty liver disease

Liu, A., Xu, C., Liu, Y., Sun, D., Jiang, L., Tang, L., Zhu, P., Chen, S., Liu, W., Wang, X., et al. (2023) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17362 · Cited by 44 · see citing works

Perfluoroalkyl substance (PFAS) exposure and risk of nonalcoholic fatty liver disease in the elderly: results from NHANES 2003–2014

Wu, Z., Ouyang, T., Liu, H., Cao, L., & Chen, W. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-26941-2 · Cited by 43 · see citing works

Perfluorooctanesulfonic Acid and Perfluorooctanoic Acid Promote Migration of Three-Dimensional Colorectal Cancer Spheroids

Zheng, J., Sun, B., Berardi, D., Lu, L., Yan, H. Y., Zheng, S., Aladelokun, O. B., Xie, Y., Cai, Y., Pollitt, K. J. G., et al. (2023) · Environmental Science & Technology · doi:10.1021/acs.est.3c04844 · Cited by 42 · see citing works

Perfluoroalkyl Substances in Water from the Yangtze River and Its Tributaries at the Dividing Point Between the Middle and Lower Reaches

Tan, K.-Y., Lu, G.-H., Yuan, X., Zheng, Y., Shao, P., Cai, J.-Y., Zhao, Y., Zhu, X., & Yang, Y. (2018) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/s00128-018-2444-z · Cited by 41 · see citing works

Exposure to perfluoroalkyl substances in early pregnancy and risk of sporadic first trimester miscarriage

Wikström, S., Hussein, G., Karlsson, A. L., Lindh, C. H., & Bornehag, C.-G. (2021) · Scientific Reports · doi:10.1038/s41598-021-82748-6 · Cited by 41 · see citing works

Depuration of perfluoroalkyl substances from the edible tissues of wild-caught invertebrate species

Taylor, M. D., Bowles, K. C., Johnson, D. D., & Moltschaniwskyj, N. A. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2016.12.116 · Cited by 40 · see citing works

A pilot study on extractable organofluorine and per- and polyfluoroalkyl substances (PFAS) in water from drinking water treatment plants around Taihu Lake, China: what is missed by target PFAS analysis?

Jiao, E., Zhu, Z., Yin, D., Qiu, Y., Kärrman, A., & Yeung, L. W. Y. (2022) · Environmental Science: Processes & Impacts · doi:10.1039/d2em00073c · Cited by 38 · see citing works

Association between perfluoroalkyl substances exposure and the prevalence of nonalcoholic fatty liver disease in the different sexes: a study from the National Health and Nutrition Examination Survey 2005–2018

Limei, E., Zhang, S., & Jiang, X. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-25258-4 · Cited by 35 · see citing works

A novel molecular pathway of lipid accumulation in human hepatocytes caused by PFOA and PFOS

Gou, X., Tian, M., Yan, L., Xia, P., Ji, H., Tan, H., Shi, W. M., Yu, H., & Zhang, X. (2024) · Environment International · doi:10.1016/j.envint.2024.108962 · Cited by 33 · see citing works

Effects of mixed exposure to PFAS on adolescent non-alcoholic fatty liver disease: Integrating evidence from human cohorts, toxicogenomics, and animal models to uncover mechanisms and potential target sites

Du, X., Li, D., Xu, X., Wu, Y., Du, Z., Liang, G., Li, Y.-Z., Zheng, Y.-J., Qin, Y., Qian, K., et al. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.136854 · Cited by 32 · see citing works

Proteomic analysis of cell proliferation in a human hepatic cell line (HL-7702) induced by perfluorooctane sulfonate using iTRAQ

Cui, R., Zhang, H., Guo, X., Cui, Q., Wang, J., & Dai, J. (2015) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2015.06.031 · Cited by 31 · see citing works

Perfluorooctane sulfonate interferes with non-genomic estrogen receptor signaling pathway, inhibits ERK1/2 activation and induces apoptosis in mouse spermatocyte-derived cells

Qu, J., Han, Y. K., Zhao, Z., Wu, Y., Lu, Y., Chen, G., Jiang, J., Qiu, L., Gu, A., & Wang, X. (2021) · Toxicology · doi:10.1016/j.tox.2021.152871 · Cited by 31 · see citing works

Exposure to Perfluoroalkyl Substances and Associations with Pubertal Onset and Serum Reproductive Hormones in a Longitudinal Study of Young Girls in Greater Cincinnati and the San Francisco Bay Area

Pinney, S. M., Fassler, C. S., Windham, G. C., Herrick, R. L., Xie, C., Kushi, L. H., & Biro, F. M. (2023) · Environmental Health Perspectives · doi:10.1289/ehp11811 · Cited by 31 · see citing works

Comparative hepatotoxicity of novel lithium bis(trifluoromethanesulfonyl)imide (LiTFSI, ie. HQ-115) and legacy Perfluorooctanoic acid (PFOA) in male mice: Insights into epigenetic mechanisms and pathway-specific responses

Sands, M., Zhang, X., Gal, A., Laws, M. J., Spinella, M. J., Erdogan, Z. M., & Irudayaraj, J. (2024) · Environment International · doi:10.1016/j.envint.2024.108556 · Cited by 28 · see citing works

Per- and poly-fluoroalkyl substances (PFAS) and human health: a review of exposure routes and potential toxicities across the lifespan

Ly, C. Y. S., Alrazihi, L. A., Wong, S. T., & Wong, S. F. (2025) · Environmental Toxicology and Chemistry · doi:10.1093/etojnl/vgaf172 · Cited by 27 · see citing works

Life cycle environmental impacts of urban water systems in China

Xu, H., Fu, G., Ye, Q., Lyu, M., & Yan, X. (2024) · Water Research · doi:10.1016/j.watres.2024.122350 · Cited by 26 · see citing works

Comparative Proteomics Highlights that GenX Exposure Leads to Metabolic Defects and Inflammation in Astrocytes

Abu-Salah, A., Cesur, M. F., Anchan, A., Ay, M., Langley, M. R., Shah, A., Reina-Gonzalez, P., Strazdins, R., Çakır, T., & Sarkar, S. (2024) · Environmental Science & Technology · doi:10.1021/acs.est.4c05472 · Cited by 25 · see citing works

Angelica sinensis polysaccharide suppresses the Wnt/β-catenin-mediated malignant biological behaviors of breast cancer cells via the miR-3187-3p/PCDH10 axis.

Cai, Y., Wang, Y., Su, W., Zhou, X.-L., & Lu, C. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116295 · Cited by 25 · see citing works

Association between per- and polyfluoroalkyl substances and semen quality

Wang, H., Wei, K., Wu, Z., Liu, F., Wang, D., Peng, X., Liu, Y., Xu, J., Jiang, A., & Zhang, Y. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-24182-3 · Cited by 23 · see citing works

Per- and Polyfluoroalkyl Substances (PFAS) in Community Water Systems (CWS) and the Risk of Thyroid Cancer: An Ecological Study

Alsen, M., Leung, A. M., & van Gerwen, M. A. G. (2023) · Toxics · doi:10.3390/toxics11090786 · Cited by 21 · see citing works

Association between per- and polyfluoroalkyl substances and sex hormone levels in males based on human studies

Sang, L., Ge, Y., Liu, F., Wei, K., Shen, X.-Y., Zhang, Y., Li, Z., Lu, W., Gao, X., & Zhang, Y. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.115998 · Cited by 19 · see citing works

Copper transporter gene ATP7A: A predictive biomarker for immunotherapy and targeted therapy in hepatocellular carcinoma

Shao, K., Shen, H., Chen, X., Shao, Z., Liu, Y., Wang, Y., Chen, H., & Wu, X. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109518 · Cited by 19 · see citing works

Speciation and biogeochemical behavior of perfluoroalkyl acids in soils and their environmental implications: A review

Guo, C., Hu, S., Cheng, P., Cheng, K., Yang, Y., Chen, G., Wang, Q., Wang, Y., & Liu, T. (2024) · Eco-Environment & Health · doi:10.1016/j.eehl.2024.05.005 · Cited by 18 · see citing works

Emerging per- and polyfluoroalkyl substance perfluoro-(3,5,7,9-tetraoxadecanoic) acid (PFO4DA) impairs steroidogenesis and spermatogenesis by suppressing StAR and CYP11A1 expression in mice

Mutalifu, L., Xie, W., Wang, D., Zhi, M., Guo, Y., & Wang, J. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.117962 · Cited by 18 · see citing works

Association of Combined PFOA, PFOS, Metals and Allostatic Load on Hepatic Disease Risk

Balogun, M., & Obeng-Gyasi, E. (2024) · Journal of Xenobiotics · doi:10.3390/jox14020031 · Cited by 18 · see citing works

Cross-Sectional Associations between Prenatal Per- and Poly-Fluoroalkyl Substances and Bioactive Lipids in Three Environmental Influences on Child Health Outcomes (ECHO) Cohorts

Suthar, H., Manea, T., Pak, D., Woodbury, M., Eick, S. M., Cathey, A. L., Watkins, D. J., Strakovsky, R. S., Ryva, B. A., Pennathur, S., et al. (2024) · Environmental Science & Technology · doi:10.1021/acs.est.4c00094 · Cited by 15 · see citing works

Exposure to Per- and Polyfluoroalkyl Substances and Timing of Puberty in Norwegian Boys: Data from the Bergen Growth Study 2

Forthun, I. H., Roelants, M., Knutsen, H. K., Haug, L. S., Iszatt, N., Schell, L. M., Jugessur, A., Bjerknes, R., Oehme, N. H. B., Madsen, A., et al. (2024) · Environmental Science & Technology · doi:10.1021/acs.est.4c06062 · Cited by 11 · see citing works

Integrative transcriptomics analysis reveals convergent toxicological effects of perfluorooctanoic acid and perfluorooctane sulfonate on human liver: Evidence from multiple models

Yang, R., Yin, N., & Faiola, F. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.138112 · Cited by 9 · see citing works

Plasma perfluoroalkyl substances and breast cancer risk in Brazilian women: a case–control study

Itoh, H., Harada, K. H., Hamada, G. S., Lyu, Z., Fujitani, T., Sassa, M. H., Yamaji, T., Tsugane, S., & Iwasaki, M. (2025) · Environmental Health · doi:10.1186/s12940-025-01168-5 · Cited by 9 · see citing works

Quantitative effects of sodium-glucose cotransporter-2 inhibitors on liver functions in patients with nonalcoholic fatty liver disease

Chen, X., Xu, C., Hu, K., Yang, Y., Zhang, Y.-J., Shi, H.-Z., Gu, Q., He, S., Zhang, C., & Wang, D. (2023) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2023.2256224 · Cited by 6 · see citing works

Association between perfluoroalkyl and polyfluoroalkyl substances exposure and reproductive longevity for female in the United States: A population-based study

Ning, A., Shao, F., Yang, Q., Ren, Y., Zhou, S., Lin, J., Chu, M., & Zhang, Y. (2026) · Toxicology Letters · doi:10.1016/j.toxlet.2026.111849 · Cited by 2 · see citing works

Per- and Polyfluoroalkyl Substances in Surface Water and Fluvial Sediments of a Rural Gulf Coast Watershed: A Year-long Spatiotemporal Assessment

Rodriguez, C. A., Schramm, M., Postma, S., McDonald, T. J., Brinkmeyer-Langford, C., & Ma, X. (2026) · ACS ES&T Water · doi:10.1021/acsestwater.6c00886

Environmental Exposure to Emerging Per‐ and Polyfluoroalkyl Substances and Cardiovascular Diseases: A Mixture Analysis

Ripon, R. K., Hassan, M. M., Volquez, M., Sola, S., Saunik, S., Govind, S. C., & Prasad, N. (2026) · Health Science Reports · doi:10.1002/hsr2.72556

Single-atom catalysts for per- and perfluoroalkyl substance photodegradation from wastewater: Mechanisms, design strategies, and environmental applications

Messaoudi, N. E., Franco, D. S. P., Georgin, J., Azizi, A. E., Benjelloun, M., Miyah, Y., Yılmazoğlu, M., Messali, M., & Al-Msiedeen, A. (2026) · Applied Catalysis A : General · doi:10.1016/j.apcata.2026.121097 · Cited by 1 · see citing works

Perfluoroalkyl substances trigger renal toxicity through mitochondrial dysfunction and oxidative stress

Lee, S. M., Park, J. H., Kim, J. Y., Lee, S., & Kim, H. S. (2026) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2026.101505

The association between exposure to per- and polyfluoroalkyl substances and the risk of metabolic syndrome in adults: A systematic review and meta-analysis

Su, Y.-H., Lin, W.-C., Wu, K. W., Hsiue, Y.-C., Chen, M., Hung, K., & Chen, P. (2026) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2026.120786

Occurrence, spatial distribution, and source implications of phenolic compounds, phthalate esters, and perfluoroalkyl substances in surface seawater of Laizhou Bay, a typical fishery ecosystem in the Bohai Sea, China

Yu, X., Yu, X., Zhang, N., Liu, J., Ding, Y., Cui, Q., Wang, X., Sun, Y., Wang, J., Xiao, L., et al. (2026) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2026.120448

Confronting Novel Alternatives of Per- and Polyfluoroalkyl Substances: From the Exposure Pathway to the Health Risk Estimation

Gao, Y.-H., Zhang, Z., Luo, H.-D., Yan, X., Liu, Y., Zhang, K., Wei, Y., & Liu, Y. (2025) · Processes · doi:10.3390/pr13124032 · Cited by 1 · see citing works

Human Exposure Pathways to Per- and Polyfluoroalkyl Substances (PFASs)—A Comprehensive Review of Sources, Physicochemical Properties, and Human Health Risk Assessment

Reindl, A. R., & Zduńczuk, J. A. (2026) · Toxics · doi:10.3390/toxics14060528 · Cited by 3 · see citing works

Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research

Fenton, S. E., Ducatman, A., Boobis, A., DeWitt, J. C., Lau, C., Ng, C., Smith, J. S., & Roberts, S. M. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4890 · Cited by 2,445 · see citing works

Overview of Per- and Polyfluoroalkyl Substances (PFAS), Their Applications, Sources, and Potential Impacts on Human Health

Habib, Z., Song, M., Ikram, S., & Zahra, Z. (2024) · Pollutants · doi:10.3390/pollutants4010009 · Cited by 121 · see citing works

Sources, occurrence and toxic effects of emerging per- and polyfluoroalkyl substances (PFAS)

Manojkumar, Y., Pilli, S., Rao, P. V., & Tyagi, R. D. (2023) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2023.107174 · Cited by 170 · see citing works