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Celastrol attenuates HFD-induced obesity and improves metabolic function independent of adiponectin signaling

Ye, L., Gao, Y., Li, X., Liang, X., Yang, Y., & Zhang, R. (2023) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2023.2250929 · Cited by 7 · see citing works

In silico transcriptome-based drug screening identifies celastrol as a multi-species therapeutic agent against aging-related sarcopenia and mitochondrial dysfunction

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Recent Advances in the Anti‐Obesity Benefits of Phytoconstituents: From Phytochemistry to Targeting Novel‐Systems

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Dehydroandrographolide succinate attenuates dexamethasone-induced skeletal muscle atrophy by regulating Akt/GSK3β and MuRF-1 pathways

Jin, H., Seo, H. S., Shin, J., Lee, K.-J., Kim, S. J., Jung, S. H., & Kim, B. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177265 · Cited by 4 · see citing works

Complex networks interactions between bioactive compounds and adipose tissue vis-à-vis insulin resistance

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Ursolic acid inhibits autophagy-dependent neuronal cell death by reducing oxidative stress levels in an in vitro model of Parkinson’s disease

Gao, J.-Y., Lei, B., He, H., Xi, D., Wu, Q., Wang, X., Li, N., Tian, Z., Zhu, Q., & Yu, Y. (2024) · Molecular & Cellular Toxicology · doi:10.1007/s13273-024-00480-4 · Cited by 3 · see citing works

Celastrol protects against cisplatin-induced ovarian toxicity via modulation of PPAR-γ and AMPK

Alhakamy, N. A., Alamoudi, A. J., Abdulaal, W. H., Choudhry, H., Asfour, H. Z., Al-Rabia, M. W., Ashour, O. M., Abdel‐Naim, A. B., Hofni, A., & Aboubakr, E. M. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04322-5 · Cited by 3 · see citing works

Celastrol Suppresses SHH ‐ MB Growth via ROS ‐Induced Stress: Evidence From In Vitro and In Vivo Studies

Wang, B., Xu, T., Yu, L., Qiu, C., Xu, J., Zhao, X., Xu, C., Tan, F., Sheng, H., Zhang, N., et al. (2025) · Phytotherapy Research · doi:10.1002/ptr.70077 · Cited by 2 · see citing works

Tripterygium hypoglaucum (Levl.) Hutch: A systematic review of its traditional uses, botany, phytochemistry, pharmacology, pharmacokinetics and toxicology

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Bioinformatics investigation for lipid accumulation mechanisms in the liver of old obese mice treated with celastrol

Yuan, Y., Zhu, G., Mei, S., Hu, H., Wang, A., Yue, Q., Yuan, X., Zhang, Y., & Jiang, S. (2025) · Egyptian Liver Journal · doi:10.1186/s43066-025-00410-6 · Cited by 1 · see citing works

Naringin Ameliorates IL-6 Mediated mitochondrial dysfunction and skeletal muscle degeneratio via AMPK/Nrf-2 pathwayPreprint

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Celastrol can inhibit the growth of SHH medulloblastoma: In vitro and in vivo studiesPreprint

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Exploring the interplay between adipokine-mediated celastrol target genes and T cells in diabetic nephropathy: a mendelian randomization-based causal inference

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The potential mechanism of celastrol attenuating atherosclerosis by promoting macrophage autophagy via AMPK/ULK1 pathway

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Celastrol exerts a neuroprotective effect by inhibiting necroptosis and inflammation in intracerebral hemorrhage-induced brain injury

Ma, W., Lu, Z., Liu, Y., Xiong, F., Wang, X., Guo, Y., Ge, J., Li, F., & Zhang, H. (2025) · Neuroreport · doi:10.1097/wnr.0000000000002237

The CD38 Inhibitor, Apigenin, Ameliorates Obesity-Related Metabolic and Inflammatory Dysfunction via Boosting the NAD+/SIRT1 Axis in Rats on High Fat Diet

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Tripterygium wilfordii: Historical origins, pharmacological mechanisms, and biosynthesis of triptolide and celastrol

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Celastrol alleviates high-fat diet-induced obesity via enhanced muscle glucose utilization and mitochondrial oxidative metabolism-mediated upregulation of pyruvate dehydrogenase complex

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Improvement of mitochondrial function by celastrol in palmitate-treated C2C12 myotubes via activation of PI3K-Akt signaling pathway

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Cellular functional roles of celastrol on mitochondrial dysfunction-induced insulin resistance

Bakar, A., & Bakar, M. H. A. (2015)

Celastrol attenuates HFD-induced obesity and improves metabolic function independent of adiponectin signaling

Ye, L., Gao, Y., Li, X., Liang, X., Yang, Y., & Zhang, R. (2023) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2023.2250929 · Cited by 7 · see citing works

Celastrol alleviates metabolic disturbance in high‐fat diet‐induced obese mice through increasing energy expenditure by ameliorating metabolic inflammation

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