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Size and burden of mental disorders in Europe—a critical review and appraisal of 27 studies
Open accessAbstract
Epidemiological data on a wide range of mental disorders from community studies conducted in European countries are presented to determine the availability and consistency of prevalence, disability and treatment findings for the EU. Using a stepwise multimethod approach, 27 eligible studies with quite variable designs and methods including over 150,000 subjects from 16 European countries were identified. Prevalence: On the basis of meta-analytic techniques as well as on reanalyses of selected data sets, it is estimated that about 27% (equals 82.7 million; 95% CI: 78.5-87.1) of the adult EU population, 18-65 of age, is or has been affected by at least one mental disorder in the past 12 months. Taking into account the considerable degree of comorbidity (about one third had more than one disorder), the most frequent disorders are anxiety disorders, depressive, somatoform and substance dependence disorders. When taking into account design, sampling and other methodological differences between studies, little evidence seems to exist for considerable cultural or country variation. Disability and treatment: despite very divergent and fairly crude assessment strategies, the available data consistently demonstrate (a) an association of all mental disorders with a considerable disability burden in terms of number of work days lost (WLD) and (b) generally low utilization and treatment rates. Only 26% of all cases had any consultation with professional health care services, a finding suggesting a considerable degree of unmet need. The paper highlights considerable future research needs for coordinated EU studies across all disorders and age groups. As prevalence estimates could not simply be equated with defined treatment needs, such studies should determine the degree of met and unmet needs for services by taking into account severity, disability and comorbidity. These needs are most pronounced for the new EU member states as well as more generally for adolescent and older populations.
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“in line with the higher prevalence of women who make use of mental healthcare services”
From Patients requesting and receiving euthanasia for psychiatric disorders in the Netherlands (2023) · cites this paper as [12]
In the citing paper
“In Europe, only about 25% of people with mental disorders receive professional treatment (Wittchen and Jacobi, 2005).”
From Feasibility of a Software agent providing a brief Intervention for Self-help to Uplift psychological wellbeing (“SISU”). A single-group pretest-posttest trial investigating the potential of SISU to act as therapeutic agent (2021) · cites this paper as Wittchen and Jacobi, 2005
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“It is the case that many with anxiety disorders have no diagnosis nor seek treatment [29,30].”
From Low-intensity internet-delivered treatment for generalized anxiety symptoms in routine care: protocol for a randomized controlled trial (2014) · cites this paper as [30]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
(1998) · The Journal of Clinical Psychiatry · Cited by 19,139
WARE, J. E., KOSINSKI, M., & KELLER, S. D. (1996) · Medical Care · doi:10.1097/00005650-199603000-00003 · Cited by 17,392 · cited 1×
“The only available cross-national and directly comparative data in this respect come from the ESEMeD study revealing that health-related quality of life (mental health score of the SF12, Ware et al., 1996) was reduced by approximately 1.0 standard deviation units in most mental disorders.”
ResultInfluentialDiagnostic and Statistical Manual of Mental Disorders
&NA; (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802020-00022 · Cited by 12,603
Kessler, R. C. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010008002 · Cited by 12,370 · cited 3×
“Consistent with the international situation and other inquiries (e.g. Kessler et al., 1994; Fryers et al., 2004), almost no community studies with established explicit diagnostic criteria were identified with regard to other mental disorders such as sleep disorders, impulse control disorders,…”
BackgroundResultDiagnostic and Statistical Manual of Mental Disorders, 3rd ed
Cooper, A. M., & Michels, R. (1981) · American Journal of Psychiatry · doi:10.1176/ajp.138.1.128 · Cited by 7,419
The mini international neuropsychiatric interview
Lecrubier, Y., Sheehan, D. V., Hergueta, T., & Weiller, E. (1998) · European Psychiatry · doi:10.1016/s0924-9338(99)80239-9 · Cited by 5,899
A scaled version of the General Health Questionnaire
Goldberg, D. P., & Hillier, V. F. (1979) · Psychological Medicine · doi:10.1017/s0033291700021644 · Cited by 5,639 · cited 1×
“We did not include studies assessing psychopathology and mental health exclusively by means of questionnaires or screening instruments (e.g. GHQ, Goldberg and Hillier, 1979; CIDI-SF, Kessler et al., 1998; MHI-5, Berwick et al., 1991).”
Method
Research works printed but not linked: 6
- Andrade, 2000, Cross-national comparisons of the prevalences and correlates of mental disorders, B. World Health Organ., 78, 413
- Jacobi, 2004, Psychische Störungen in der Allgemeinbevölkerung: Inanspruchnahme von Gesundheitsleistungen und Ausfalltage, Bundesgesundheitsblatt Gesundh. Forsch. Gesundh.Schutz, 47, 736
- Meyer, 2001, Prevalence of DSM-IV psychiatric disorders including nicotine dependence in the general population: results from the northern german TACOS study, Neurol. Psychiatr. Br., 9, 75
- Szadoczky, 2000, A hangulat- es szorongasos zavarok elöfordulasa a felnott magyar lakossag köreben, Orv. Hetil., 141, 17
- The WHO World Mental Health Survey Consortium, 2004, Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys, J. Am. Med. Assoc., 291, 2581, 10.1001/jama.291.21.2581 · DOI · Paper page
- Wittchen, 2003, Depression—an underdiagnosed disease, Medicographia, 25, 9
Cited by
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Items 301–400 of 1,000
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“The burden of the disease is higher by 50% in females than in males [7].”
BackgroundMental health and well-being in a 6-year follow-up of patients with depression
Koivumaa-Honkanen, H. T., Tuovinen, T. K., Honkalampi, K. M., Antikainen, R., Hintikka, J. J., Haatainen, K. M., & Viinamäki, H. T. (2008) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-008-0353-x · Cited by 54
Helbig‐Lang, S., Rusch, S., & Lincoln, T. M. (2014) · Journal of Clinical Psychology · doi:10.1002/jclp.22135 · Cited by 54
Andlin‐Sobocki, P., & Rehm, J. T. (2005) · European Journal of Neurology · doi:10.1111/j.1468-1331.2005.01194.x · Cited by 54
Long-Term Impact of War on Healthcare Costs: An Eight-Country Study
Sabés-Figuera, R., McCrone, P., Bogić, M., Ajduković, D., Frančišković, T., Colombini, N., Kučukalić, A., Lečić‐Toševski, D., Nexhmedin Morina, B., Popovski, M., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029603 · Cited by 53
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BackgroundMöller, H. ‐., Bitter, I., Bobes, J., Fountoulakis, K. Ν., Höschl, C., & Kasper, S. F. (2011) · European Psychiatry · doi:10.1016/j.eurpsy.2011.08.002 · Cited by 53
“Depression is one of the most prevalent psychiatric disorders [3,206] and leads to substantial suffering of the patients, a heavy burden for the family, a high risk of suicidal behaviour (lifetime risk of suicide up to 15%) and significant socioeconomic”
BackgroundPiubelli, C., Carboni, L., Becchi, S., Mathé, A. A., & Domenici, E. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.12.043 · Cited by 53
“All righ doi:10.1016/j.neuroscience.2010.12.043 349 Major depressive disorder (MDD) is a severe and disabling disease, affecting each year about 7% of the adult European population and causing a heavy burden of disease and reduction in quality of life (Wittchen and Jacobi, 2005).”
BackgroundInfluentialThe Psychosocial Screen for Cancer (PSSCAN): Further validation and normative data
Linden, W., Vodermaier, A., McKenzie, R., Barroetavena, M. C., Yi, D., & Doll, R. (2009) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-7-16 · Cited by 53
Dunn, E. C., Sofer, T., Gallo, L. C., Gogarten, S. M., Kerr, K. F., Chen, C., Stein, M. B., Ursano, R. J., Guo, X., Jia, Y., et al. (2016) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32448 · Cited by 56
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BackgroundZheng, Y., & Cui, Y. (2016) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s106752 · Cited by 53
“4% in the US(2) and 27% in European countries.(3) The total number of depression patients in the People’s Republic of China has reached 90 million(1) and continues to rise, compromising the health of the general population.”
Vitamin D3 supplementation and treatment outcomes in patients with depression (D3-vit-dep)
Hansen, J. P., Pareek, M., Hvolby, A., Schmedes, A., Toft, T., Dahl, E., & Nielsen, C. T. (2019) · BMC Research Notes · doi:10.1186/s13104-019-4218-z · Cited by 58
“9%, leading to massive health-related and economic consequences [2].”
Heinig, I., Wittchen, H.-U., & Knappe, S. (2021) · Community Mental Health Journal · doi:10.1007/s10597-020-00767-5 · Cited by 54
Bøen, H., Dalgard, O. S., Johansen, R., & Nord, E. (2012) · BMC Geriatrics · doi:10.1186/1471-2318-12-20 · Cited by 53
Samuelsson, Å., Alexanderson, K. A. E., Ropponen, A., Lichtenstein, P., & Svedberg, P. (2012) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-012-0498-5 · Cited by 52
“Recent figures indicate that the 12-month prevalence of mental disorders is 18–36 % globally [2] and 27 % among the EU population [3].”
BackgroundXavier, M., Baptista, H., Mendes, J. M., Magalhães, P. C., & Caldas‐de‐Almeida, J. M. (2013) · International Journal of Mental Health Systems · doi:10.1186/1752-4458-7-19 · Cited by 52
“4% of the EU population aged 18 to 65 suffer from one type or another of mental health problem during each one-year period [4], a number that has been recently updated to 38,2% after the inclusion of data from a broader childhood and adolescence assessment, as well as from new EU member states [5].”
BackgroundAnticipation of interoceptive threat in highly anxiety sensitive persons
Melzig, C. A., Michałowski, J. M., Holtz, K., & Hamm, A. O. (2008) · Behaviour Research and Therapy · doi:10.1016/j.brat.2008.07.002 · Cited by 52
Cross-cultural validation of the German and Turkish versions of the PHQ-9: an IRT approach
Reich, H., Rief, W., Brähler, E., & Mewes, R. (2018) · BMC Psychology · doi:10.1186/s40359-018-0238-z · Cited by 52
“Depression is a highly prevalent disorder leading to suffering and disability [1, 2].”
BackgroundRole of nesfatin-1 in anxiety, depression and the response to stress
Weibert, E., Hofmann, T., & Stengel, A. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.09.037 · Cited by 54
Formánek, T., Kågström, A., Čermáková, P., Csémy, L., Mladá, K., & Winkler, P. (2019) · European Psychiatry · doi:10.1016/j.eurpsy.2019.05.001 · Cited by 55
“Approximately 25% of people experience a mental disorder every year [4,5], but the majority of people affected do not receive help due to an array of factors, including stigmatization of mental illness and a lack of access to adequate services [6,7].”
BackgroundDoes religiosity ameliorate the negative impact of obsessive-compulsive disorder on self-esteem?
Ghafoor, H., Schulz, S. M., & Mohsin, H. (2018) · Mental Health Religion & Culture · doi:10.1080/13674676.2018.1458082 · Cited by 8
Sloover, M., van Est, L. A. C., Janssen, P. G. J., Hilbink, M., & van Ee, E. (2022) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2022.102641 · Cited by 55
Eating disorders and eating pathology in young adult and adult patients with ESSENCE
Karjalainen, L., Gillberg, C., Råstam, M., & Wentz, E. (2016) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2015.12.009 · Cited by 51
“5% for BN [5–7] and BED for approximately 3% [8].”
BackgroundBrailovskaia, J., Schönfeld, P., Kochetkov, Y., & Margraf, J. (2017) · Current Psychology · doi:10.1007/s12144-017-9627-3 · Cited by 68
Mental health, family roles and employment status inside and outside the household in Spain
de la Torre, J. A., Molina, A. J., Fernández‐Villa, T., Artazcoz, L., & Martín, V. (2018) · Gaceta Sanitaria · doi:10.1016/j.gaceta.2017.11.005 · Cited by 51
Obsessive-Compulsive Disorder:Boundary Issues
Fineberg, N. A., Saxena, S., Zohar, J., & Craig, K. J. (2007) · CNS Spectrums · doi:10.1017/s1092852900021167 · Cited by 51
Competence and Vulnerability in Biomedical Research
Bielby, P. (2008) · International library of ethics, law, and the new medicine/The international library of ethics, law, and the new medicine · doi:10.1007/978-1-4020-8604-5 · Cited by 51
EARLY-LIFE PREDICTORS OF INTERNALIZING SYMPTOM TRAJECTORIES IN CANADIAN CHILDREN
Weeks, M., Cairney, J., Wild, T. C., Ploubidis, G. B., Naicker, K., & Colman, I. (2014) · Depression and Anxiety · doi:10.1002/da.22235 · Cited by 57
“This was not surprising, considering studies showing not only that rates of depression and anxiety are higher among girls,[48, 49] but that these gender differences tend to emerge in adolescence.”
BackgroundWeich, S., McBride, O., Hussey, D., Exeter, D. J., Brugha, T. S., & McManus, S. (2011) · Psychological Medicine · doi:10.1017/s0033291711000249 · Cited by 52
“Latent class analysis of co-morbidity in the Adult”
BackgroundMoser, D., Molitor, A. M., Kumsta, R., Tatschner, T., Riederer, P. F., & Meyer, J. (2007) · The World Journal of Biological Psychiatry · doi:10.1080/15622970701429862 · Cited by 50
Brandenberg, G., Ozimek, P., Bierhoff, H., & Janker, C. (2018) · Behaviour and Information Technology · doi:10.1080/0144929x.2018.1545049 · Cited by 56
“Depression represents one of the most common mental disorders worldwide (Bretschneider, Kuhnert, and Hapke 2017; Davidson et al. in press; Wittchen and Jacobi 2005).”
BackgroundPerformance Measurement for Health System ImprovementPreprint
Smith, P., Mossialos, E. A., Papanicolas, I., & Leatherman, S. T. (2010) · RePEc: Research Papers in Economics · Cited by 50
Bøen, H. (2012) · Norsk Epidemiologi · doi:10.5324/nje.v22i2.1574 · Cited by 48
“Strong support 275 (21) 227 (26) 502 (23)”
BackgroundArends, I., Bültmann, U., van Rhenen, W., Groen, H., & van der Klink, J. J. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071937 · Cited by 49
Daily Life Behaviors and Depression Risk Following Stroke
Jean, F. A. M., Swendsen, J. D., Sibon, I., Fehér, K. D., & Husky, M. M. (2013) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988713484193 · Cited by 49
Kravets, J. L., Reyes, B. A. S., Unterwald, E. M., & Bockstaele, E. J. V. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0674-8 · Cited by 49
“As the most prevalent class of mental disorders in the general population, anxiety disorders are a major global health issue impacting millions of lives each year (Kessler et al. 2009; Somers et al. 2006; Wittchen and Jacobi 2005).”
Asselmann, E., Wïttchen, H., Lieb, R., & Beesdo‐Baum, K. (2017) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-017-1436-3 · Cited by 58
Høifødt, R. S., Waterloo, K. K., Wang, C. E. A., Eisemann, M. R., Figenschau, Y., & Halvorsen, M. B. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.08.024 · Cited by 53
Course and predictors of medically unexplained pain symptoms in the general population
Leiknes, K. A., Finset, A., Moum, T., & Sandanger, I. (2007) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2006.08.009 · Cited by 50
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Jorm, A. F., Kitchener, B. A., Kanowski, L. G., & Kelly, C. (2007) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 48
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Maercker, A. R. A., Povilonyte, M., Lianowa, R., & Pöhlmann, K. (2009) · European Psychologist · doi:10.1027/1016-9040.14.3.249 · Cited by 48
Towards personalised ambient monitoring of mental health via mobile technologies
Prociów, P., & Crowe, J. A. (2010) · Technology and Health Care · doi:10.3233/thc-2010-0590 · Cited by 48
“Bipolar disorder (BD) is a condition that affects almost 2% o f the European population [16].”
Childhood and Current Determinants of Heavy Drinking in Early Adulthood
Kestilä, L., Martelin, T. P., Rahkonen, O., Joutsenniemi, K., Pirkola, S. P., Poikolainen, K., & Koskinen, S. V. P. (2008) · Alcohol and Alcoholism · doi:10.1093/alcalc/agn018 · Cited by 49
Hjarsbech, P. U., Andersen, R. V., Christensen, K. B., Aust, B., Borg, V., & Rugulies, R. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.07.033 · Cited by 48
van den Berg, N., Grabe, H.-J., Freyberger, H. J., & Hoffmann, W. (2011) · BMC Psychiatry · doi:10.1186/1471-244x-11-30 · Cited by 47
“The German findings are comparable to those in other European countries [4].”
BackgroundResultKimura, I., Kagawa, S., Tsuneki, H., Tanaka, K. Y., & Nagashima, F. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108159 · Cited by 47
BMJ Publishing Group Ltd (2006) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2006.089540 · Cited by 48
Human well-being responses to species’ traits
Fisher, J. C., Dallimer, M., Irvine, K. N., Aizlewood, S. G., Austen, G. E., Fish, R. D., King, P. M., & Davies, Z. G. (2023) · Nature Sustainability · doi:10.1038/s41893-023-01151-3 · Cited by 51
“This is pertinent in locations where the prevalence of mental ill health is particularly high (for example, in Europe 7 ) and given that human well-being is a predictor of both life expectancy and mortality 8,9 .”
BackgroundAdult hippocampal neurogenesis: An actor in the antidepressant-like action
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BackgroundIpser, J., Dewing, S., & Stein, D. J. (2007) · Current Psychiatry Reports · doi:10.1007/s11920-007-0037-3 · Cited by 46
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Creed, F. H., BARSKY, A. J., & Leiknes, K. A. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511977862.002 · Cited by 48
Varga, Z. K., Zsigmond, Á., Pejtsik, D., Varga, M., Demeter, K., Mikics, É., Haller, J., & Aliczki, M. (2018) · Scientific Reports · doi:10.1038/s41598-018-34989-1 · Cited by 48
SPECIFIC PHOBIA AMONG U.S. ADOLESCENTS: PHENOMENOLOGY AND TYPOLOGY
Burstein, M., Georgiades, K., He, J., Schmitz, A. P., Feig, E. H., Khazanov, G. K., & Merikangas, K. R. (2012) · Depression and Anxiety · doi:10.1002/da.22008 · Cited by 45
Co-morbidities of vertiginous diseases
Warninghoff, J. C., Bayer, O., Ferrari, U., & Straube, A. (2009) · BMC Neurology · doi:10.1186/1471-2377-9-29 · Cited by 44
Zhang, R., Zhang, T., Ali, A. M., Washih, M. A., Pickard, B. S., & Watson, D. G. (2016) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2016.02.003 · Cited by 44
Asselmann, E., Wïttchen, H., Lieb, R., Perkonigg, A., & Beesdo‐Baum, K. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.10.004 · Cited by 48
Socio-demographic Differences in Self-reported Psychological Distress Among 25- to 64-Year-Old Finns
Talala, K. M., Huurre, T. M., Aro, H. M., Martelin, T. P., & Prättälä, R. (2007) · Social Indicators Research · doi:10.1007/s11205-007-9153-z · Cited by 45
Military and Veteran help-seeking behaviors: Role of mental health stigma and leadership
McGuffin, J., Riggs, S. A., Raiche, E., & Romero, D. H. (2021) · Military Psychology · doi:10.1080/08995605.2021.1962181 · Cited by 44
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BackgroundYang, L., Sun, J., Nan, Y., Waqas, A., Nisar, A., Wang, D., Rahman, A., & Li, X. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.11.075 · Cited by 47
A Consensus Statement for Safety Monitoring Guidelines of Treatments for Major Depressive Disorder
Dodd, S., Malhi, G. S., Tiller, J. W. G., Schweitzer, I., Hickie, I. B., Khoo, J., Bassett, D. L., Lyndon, B., Mitchell, P. B., Parker, G. B., et al. (2011) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048674.2011.595686 · Cited by 45
Mental Health Service Use Among Chinese Adults With Mental Disabilities: A National Survey
Li, N., Du, W., Gong, C., Song, X., & Zheng, X. (2013) · Psychiatric Services · doi:10.1176/appi.ps.001232012 · Cited by 44
Wie stark sind Führungskräfte psychisch gefährdet?
Zimber, A., Hentrich, S., Bockhoff, K., Wissing, C., & Petermann, F. (2015) · Zeitschrift für Gesundheitspsychologie · doi:10.1026/0943-8149/a000143 · Cited by 48
Kong, W., Deng, H., Wan, J., Zhou, Y., Zhou, Y., Song, B., & Wang, X. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.580858 · Cited by 48
Antidepressant pharmacogenetics
Singh, A., Bousman, C., Ng, C. H., & Berk, M. (2013) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000023 · Cited by 44
Harro, J., Kanarik, M., Matrov, D., & Panksepp, J. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.02.016 · Cited by 45
Biological Markers of Generalized Anxiety Disorder
Maron, E., & Nutt, D. (2018) · Focus · doi:10.1176/appi.focus.16205 · Cited by 42
Escitalopram: A Review of its Use in the Management of Anxiety Disorders
Dhillon, S., Scott, L. J., & Plosker, G. L. (2006) · CNS Drugs · doi:10.2165/00023210-200620090-00010 · Cited by 47
Lester, K., Seal, K., Nightingale, Z. C., & Field, A. (2010) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2009.09.004 · Cited by 46
Proportion of patients without mental disorders being treated in mental health services worldwide
Bruffaerts, R., Posada‐Villa, J., Al-Hamzawi, A. O., Gureje, O., Huang, Y., Hu, C., Bromet, E. J., Viana, M. C., Hinkov, H. R., Karam, E. G., et al. (2014) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.113.141424 · Cited by 42
Wabich, J., Bellaguarda, E., Joyce, C., Keefer, L., & Kinsinger, S. W. (2020) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-020-09710-y · Cited by 42
“This corresponds with numerous studies demonstrating higher rates of disordered eating among women in the general population (Wittchen & Jacobi, 2005; Hoek, 2006).”
ResultWork-related Violence and Incident Use of Psychotropics
Madsen, I. E. H., Burr, H., Diderichsen, F., Pejtersen, J. H., Borritz, M., Bjørner, J. B., & Rugulies, R. (2011) · American Journal of Epidemiology · doi:10.1093/aje/kwr259 · Cited by 42
“This is of methodological concern, because most mental disorders are untreated (38), and treatments also include nonpharmaceutical options such as psychotherapy (38).”
BackgroundDewa, C. S., & McDaid, D. (2010) · Springer eBooks · doi:10.1007/978-1-4419-0428-7_2 · Cited by 46
Menke, A. (2018) · Pharmacogenomics and Personalized Medicine · doi:10.2147/pgpm.s146110 · Cited by 41
“However, less than one-third of all patients receive any treatment in Europe.(3) The suicide rate is higher than the annual mortality from AIDS, most forms of cancer, and homicide.”
BackgroundJuul, S., Poulsen, S., Lunn, S., Sørensen, P. S., Jakobsen, J. C., & Simonsen, S. (2019) · Systematic Reviews · doi:10.1186/s13643-019-1099-0 · Cited by 45
Patients of immigrant origin in inpatient psychiatric facilities
Schouler‐Ocak, M., Bretz, H. J., Penka, S., Koch, E., Hartkamp, N., Siefen, R. G., Schepker, R., Özek, M., Hauth, I., & Heinz, A. (2008) · European Psychiatry · doi:10.1016/s0924-9338(08)70058-0 · Cited by 41
Effects of the LHRH antagonist Cetrorelix on the brain function in mice
Telegdy, G., Tanaka, M., & Schally, A. V. (2009) · Neuropeptides · doi:10.1016/j.npep.2009.03.001 · Cited by 41
Carlucci, L., Watkins, M. W., Sergi, M. R., Cataldi, F., Saggino, A., & Balsamo, M. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.02345 · Cited by 51
Thompson, C. W., de Oliveira, E. S., Tilley, S., Elizalde, A., Botha, W., Briggs, A. H., Cummins, S., Leyland, A. H., Roe, J. J., Aspinall, P., et al. (2019) · Public Health Research · doi:10.3310/phr07020 · Cited by 43
“Social intervention (n) Number of participants Intervention site A Intervention site B Intervention site C Public event (11) 168 272 80 Photography workshop (7) 8 10 6 Health walk (9) 14 43 n/a Summer club (during school holidays) (8) 77 51 n/a School/nursery school session (11) 108 46 n/a Green gym (11) 10 12 n/a Com…”
BackgroundMethodInfluentialThompson, C. W., Elizalde, A., Cummins, S., Leyland, A. H., Botha, W., Briggs, A. H., Tilley, S., de Oliveira, E. S., Roe, J. J., Aspinall, P., et al. (2019) · Sustainability · doi:10.3390/su11123317 · Cited by 41
“Living in urban environments, especially for those living in relative poverty, has been associated with high levels of stress and poor mental health [1,2].”
BackgroundWelcome, M. O. (2020) · PharmaNutrition · doi:10.1016/j.phanu.2020.100176 · Cited by 41
Balkaran, B. L., Jaffe, D. H., Umuhire, D., Rive, B., & Milz, R. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03255-6 · Cited by 41
Mitchell, A. J., & Kakkadasam, V. (2010) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2010.05.012 · Cited by 41
“Depression is one of the most common of all chronic health problems worldwide and yet one that is often overlooked (Wittchen and Jacobi, 2005; WHO, 2001, 2004; Mitchell et al., 2009).”
BackgroundRancāns, E., Vrubļevska, J., Snikere, S., Koroļeva, I., & Trapencieris, M. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.11.022 · Cited by 41
Arends, I., Bültmann, U., Nielsen, K. M., van Rhenen, W., de Boer, M. R., & van der Klink, J. J. L. (2013) · Social Science & Medicine · doi:10.1016/j.socscimed.2013.10.041 · Cited by 41
Angdembe, M., Kohrt, B. A., Jordans, M., Rimal, D., & Luitel, N. P. (2017) · International Journal of Mental Health Systems · doi:10.1186/s13033-017-0176-9 · Cited by 39
Tønning, M. L., Kessing, L. V., Bardram, J. E., & Faurholt-Jepsen, M. (2019) · Journal of Medical Internet Research · doi:10.2196/15362 · Cited by 40
“Across European countries, 27% of the adult population suffers from at least one psychiatric disorder [3].”
BackgroundThe Loss of Glutamate-GABA Harmony in Anxiety Disorders
Joanna, M. W., Stachowicz, K., Nowak, G., & Pilc, A. (2011) · InTech eBooks · doi:10.5772/19919 · Cited by 40
Depression als komorbide Störung in der primärärztlichen Versorgung
Pieper, L., Schulz, H., Klotsche, J., Eichler, T. S., & Wïttchen, H. (2008) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s00103-008-0509-6 · Cited by 43
"One in four" with a mental health problem: the anatomy of a statistic
Ginn, S., & Horder, J. (2012) · BMJ · doi:10.1136/bmj.e1302 · Cited by 40
Trends in change of mental health status in the population of Tehran between 1998 and 2007.
Noorbala, A. A., Yazdi, S. A. B., & Hafezi, M. (2012) · PubMed · Cited by 40
Vermeiden, M., Janssens, M., Thewissen, V., Akinsola, E. F., Peeters, S. C. T., Reijnders, J. S. A. M., Jacobs, N., van Os, J., & Lataster, J. (2019) · BMC Psychiatry · doi:10.1186/s12888-019-2210-8 · Cited by 41
Preventing mental illness: closing the evidence-practice gap through workforce and services planning
Furber, G., Segal, L., Leach, M., Turnbull, C., Procter, N. G., Diamond, M., Miller, S., & McGorry, P. D. (2015) · BMC Health Services Research · doi:10.1186/s12913-015-0954-5 · Cited by 52
Screening for depression in the older long-term unemployed
Liwowsky, I., Kramer, D., Mergl, R., Bramesfeld, A., Allgaier, A., Pöppel, E., & Hegerl, U. (2008) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-008-0478-y · Cited by 38
Bailey, J., Dawson, G. R., Dourish, C. T., & Nutt, D. (2011) · Journal of Psychopharmacology · doi:10.1177/0269881111408455 · Cited by 41
Schröder, A., & Fink, P. (2011) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2011.05.008 · Cited by 39
Vrubļevska, J., Renemane, L., Ķīvīte‐Urtāne, A., & Rancāns, E. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.972628 · Cited by 43
“It is estimated that the prevalence of diagnosis and treatment of anxiety disorders in primary care is much lower than expected, given their prevalence (15).”
BackgroundExpression and Activity of Metalloproteinases in Depression
Bobińska, K., Szemraj, J., Czarny, P. L., & Gałecki, P. (2016) · Medical Science Monitor · doi:10.12659/msm.895978 · Cited by 39
“Depression is one of the most common mental disorders [1,2].”
BackgroundFunctioning mediates help-seeking for mental problems in the general population
Michel, C., Schnyder, N., Schmidt, S. J., Groth, N., SCHIMMELMANN, B. G., & Schultze‐Lutter, F. (2018) · European Psychiatry · doi:10.1016/j.eurpsy.2018.06.009 · Cited by 39
“For the frequently reported depressive problems/ disorders (major depression or dysthymia), which have been associated with the highest burden worldwide [1,11,46], the reported rate of any current help-seeking at almost 20% was comparably high [23,47].”
BackgroundThe Mental Health of Refugees and Forcibly Displaced People: A Narrative Review
Sukiasyan, S. H. (2024) · Consortium Psychiatricum · doi:10.17816/cp15552 · Cited by 38
Gender Differences in Prevalence of Somatoform Disorders in Patients Visiting Primary Care Centers
Bener, A., Ghuloum, S., & Burgut, F. T. (2010) · Journal of Primary Care & Community Health · doi:10.1177/2150131909353333 · Cited by 38
Culture and the Anxiety Disorders: Recommendations for DSM-V
Lewis‐Fernández, R., Hinton, D. E., Laria, A. J., Patterson, E. H., Hofmann, S. G., Craske, M. G., Stein, D. J., Asnaani, A., & Liao, B. (2011) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.9.3.foc351 · Cited by 47
Metadata
- Authors
- Wittchen, H.-U., & Jacobi, F.
- Affiliations
- Max Planck Institute of Psychiatry (DE)
- ORCID
- Jacobi, Frank
- Venue
- European Neuropsychopharmacology
- Publisher
- Elsevier BV
- Published
- 2005-08
- Volume
- 15
- Issue
- 4
- Pages
- 357-376
- ISSN
- 0924-977X (ISSN-L)
- OpenAlex
- W2107900025
- Cited by
- 1,503
- References
- 140
- Citations by year
- 2026: 14 · 2025: 31 · 2024: 43 · 2023: 64 · 2022: 48 · 2021: 46 · 2020: 57 · 2019: 58 · 2018: 64 · 2017: 75 · 2016: 83 · 2015: 84 · 2014: 103 · 2013: 110 · 2012: 121
- FWCI
- 96.18
- Type
- journal article
- Language
- en
- Open access
- green
- tud.qucosa.de
- Licence
- Locations
- European Neuropsychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Qucosa (Saxon State and University Library Dresden) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Studies
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Keywords
- mental illness, prevalence, disability burden, treatment utilization, unmet needs, comorbidities, anxiety disorders, depression, somatoform disorders, substance dependence, lost workdays, European Union, cross-national comparison, adolescent mental health, older adults
- MeSH terms
- Absenteeism, Adolescent, Adult, Age Factors, Aged, Mental Disorders, Disability Evaluation, Europe, Female, Humans, Male, Mental Health Services, Middle Aged, Quality of Life, Residence Characteristics, Review Literature as Topic, Sex Factors, Comorbidity, Prevalence, Cost of Illness, Diagnosis, Dual (Psychiatry), Quality-Adjusted Life Years
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