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Size and burden of mental disorders in Europe—a critical review and appraisal of 27 studies
Open accessAbstract
Epidemiological data on a wide range of mental disorders from community studies conducted in European countries are presented to determine the availability and consistency of prevalence, disability and treatment findings for the EU. Using a stepwise multimethod approach, 27 eligible studies with quite variable designs and methods including over 150,000 subjects from 16 European countries were identified. Prevalence: On the basis of meta-analytic techniques as well as on reanalyses of selected data sets, it is estimated that about 27% (equals 82.7 million; 95% CI: 78.5-87.1) of the adult EU population, 18-65 of age, is or has been affected by at least one mental disorder in the past 12 months. Taking into account the considerable degree of comorbidity (about one third had more than one disorder), the most frequent disorders are anxiety disorders, depressive, somatoform and substance dependence disorders. When taking into account design, sampling and other methodological differences between studies, little evidence seems to exist for considerable cultural or country variation. Disability and treatment: despite very divergent and fairly crude assessment strategies, the available data consistently demonstrate (a) an association of all mental disorders with a considerable disability burden in terms of number of work days lost (WLD) and (b) generally low utilization and treatment rates. Only 26% of all cases had any consultation with professional health care services, a finding suggesting a considerable degree of unmet need. The paper highlights considerable future research needs for coordinated EU studies across all disorders and age groups. As prevalence estimates could not simply be equated with defined treatment needs, such studies should determine the degree of met and unmet needs for services by taking into account severity, disability and comorbidity. These needs are most pronounced for the new EU member states as well as more generally for adolescent and older populations.
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“in line with the higher prevalence of women who make use of mental healthcare services”
From Patients requesting and receiving euthanasia for psychiatric disorders in the Netherlands (2023) · cites this paper as [12]
In the citing paper
“In Europe, only about 25% of people with mental disorders receive professional treatment (Wittchen and Jacobi, 2005).”
From Feasibility of a Software agent providing a brief Intervention for Self-help to Uplift psychological wellbeing (“SISU”). A single-group pretest-posttest trial investigating the potential of SISU to act as therapeutic agent (2021) · cites this paper as Wittchen and Jacobi, 2005
In the citing paper
“It is the case that many with anxiety disorders have no diagnosis nor seek treatment [29,30].”
From Low-intensity internet-delivered treatment for generalized anxiety symptoms in routine care: protocol for a randomized controlled trial (2014) · cites this paper as [30]
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Bühringer, G. (2008) · Springer eBooks · doi:10.1007/978-1-4020-5614-7_3388 · Cited by 11
Agomelatine in treating generalized anxiety disorder
Demyttenaere, K. (2014) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2014.911840 · Cited by 11
“9 -- 9% in general medical practice [5-7].”
BackgroundBrožka, H., Radostová, D., Pištíková, A., Valeš, K., & Stuchlı́k, A. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.09.042 · Cited by 10
Cebrino, J., & de la Cruz, S. P. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9072199 · Cited by 10
“2% in the general European adult population [6,7], due to the inclusion of new disorders and of new European member states.”
BackgroundHair Cortisol Concentration as a Biomarker of Symptoms of Depression in the Perinatal Period
Cauli, O., Mlili, N. E., & Ahabrach, H. (2022) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527321666220316122605 · Cited by 10
Klimas, J., Neary, A., McNicholas, C., Meagher, D. J., & Cullen, W. (2014) · Mental Health and Substance Use · doi:10.1080/17523281.2014.939221 · Cited by 10
Choate, L. H. (2010) · Journal of College Counseling · doi:10.1002/j.2161-1882.2010.tb00049.x · Cited by 10
History of psychiatry in Sweden during a millennium
Wetterberg, L. (2011) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2011.590605 · Cited by 10
Online-Therapie – eine neue Perspektive in der Psychotherapie für Flüchtlinge und Asylbewerber?
Wagner, B. (2016) · Psychotherapie Forum · doi:10.1007/s00729-016-0074-7 · Cited by 14
Negative urgency and the dual pathway model of bulimic symptoms: A longitudinal analysis
Puccio, F., Fuller‐Tyszkiewicz, M., Buck, K., & Krug, I. (2018) · European Eating Disorders Review · doi:10.1002/erv.2647 · Cited by 10
“…include only females in this study was made because eating disturbances, including bulimia nervosa and dietary restraint, primarily affect women (Hoek, 2006; Streigel‐Moore & Bulik, 2007; Wittchen & Jacobi, 2005), and there is also a paucity of research on males regarding the variables of interest.”
BackgroundMental health problems of reproductive age group women in a rural community of south west Nigeria
Soyannwo, T., Adebayo, A. M., & Sigbeku, O. A. (2018) · Journal of Mental Health · doi:10.1080/09638237.2018.1487533 · Cited by 10
Mark, K. M., Murphy, D., Stevelink, S. A. M., & Fear, N. T. (2019) · Healthcare · doi:10.3390/healthcare7010018 · Cited by 11
Barnes, M., Kessler, D. S., Archer, C., & Wiles, N. (2019) · BMC Family Practice · doi:10.1186/s12875-019-0996-6 · Cited by 12
“Anxiety disorders are more chronic than other common mental health disorders [2] but rates of diagnosis and treatment are lower than expected [3].”
BackgroundEbrahimi, H., Movaghari, M., Bazghaleh, M., Shirmohamadi, N., & Mohammadpourhodki, R. (2019) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2018-0244 · Cited by 11
Anxiety disorders in outpatient clinics of epilepsy in tertiary care hospitals: A meta-analysis
Yang, T., Kim, D.-H., Kim, Y., Kim, J., & Kwon, O. (2019) · Seizure · doi:10.1016/j.seizure.2019.12.011 · Cited by 10
Katı, C., Karadaş, S., Aslan, M., Gönüllü, H., Duran, L., & Demir, H. (2013) · The Journal of Membrane Biology · doi:10.1007/s00232-013-9606-z · Cited by 10
“logical stress (Wittchen and Jacobi 2005; Tuthill et al. 2006), whereas others have shown a decrease in ROS production (Krömer et al.”
Mental Health Symptoms Among Street-Based Psychostimulant Injectors in Sydney's Kings Cross
Topp, L., Hudson, S. L., & Maher, L. (2010) · Substance Use & Misuse · doi:10.3109/10826080903443586 · Cited by 10
Welkenhuysen, M., Gligorijević, I., Ameye, L., Prodanov, D., Huffel, S. V., & Nuttin, B. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2012.11.019 · Cited by 10
McDaid, D., Knapp, M. R. J., Curran, C., & THE MHEEN GROUP (2006) · Epidemiologia e Psichiatria Sociale · doi:10.1017/s1121189x00004310 · Cited by 10
Orešković, S. (2016) · PubMed · Cited by 10
Treasure, J. L. (2008) · Medicine · doi:10.1016/j.mpmed.2008.05.003 · Cited by 10
Sedláčková, N., Ponechalová, V., Ujházy, E., Dubovický, M., & Mach, M. (2011) · Interdisciplinary Toxicology · doi:10.2478/v10102-011-0032-8 · Cited by 10
“More than 27% of adult Europeans are estimated to experience at least one form of mental ill health during any one year (Wittchen & Jacobi, 2005).”
Background
Metadata
- Authors
- Wittchen, H.-U., & Jacobi, F.
- Affiliations
- Max Planck Institute of Psychiatry (DE)
- ORCID
- Jacobi, Frank
- Venue
- European Neuropsychopharmacology
- Publisher
- Elsevier BV
- Published
- 2005-08
- Volume
- 15
- Issue
- 4
- Pages
- 357-376
- ISSN
- 0924-977X (ISSN-L)
- OpenAlex
- W2107900025
- Cited by
- 1,503
- References
- 140
- Citations by year
- 2026: 14 · 2025: 31 · 2024: 43 · 2023: 64 · 2022: 48 · 2021: 46 · 2020: 57 · 2019: 58 · 2018: 64 · 2017: 75 · 2016: 83 · 2015: 84 · 2014: 103 · 2013: 110 · 2012: 121
- FWCI
- 96.18
- Type
- journal article
- Language
- en
- Open access
- green
- tud.qucosa.de
- Licence
- Locations
- European Neuropsychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Max Planck Institute for Plasma Physics (submittedVersion)
- Qucosa (Saxon State and University Library Dresden) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Studies
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Keywords
- mental illness, prevalence, disability burden, treatment utilization, unmet needs, comorbidities, anxiety disorders, depression, somatoform disorders, substance dependence, lost workdays, European Union, cross-national comparison, adolescent mental health, older adults
- MeSH terms
- Absenteeism, Adolescent, Adult, Age Factors, Aged, Mental Disorders, Disability Evaluation, Europe, Female, Humans, Male, Mental Health Services, Middle Aged, Quality of Life, Residence Characteristics, Review Literature as Topic, Sex Factors, Comorbidity, Prevalence, Cost of Illness, Diagnosis, Dual (Psychiatry), Quality-Adjusted Life Years
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