Impact of isolated teratozoospermia on the outcome of intrauterine insemination
Open accessAbstract
One thousand six hundred forty-one IUI cycles performed in 615 couples were categorized, depending on the semen analysis of the male partner, in three groups of: normozoospermia, teratozoospermia, and male factor infertility. Clinical pregnancies and live births per cycle were significantly decreased in the teratozoospermia group when compared to the normozoospermia group, with the exception of the first IUI attempt (comparable outcomes), whereas the cumulative live birth rate after four IUI attempts was significantly lower in the teratozoospermia and male factor infertility groups.
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Another study showed that the cumulative live birth rate after four IUI attempts from 1,641 IUI cycles was significantly lower in the teratozoospermia groups (30.32% vs. 53.22%, P<0.001).
“Further, another study also showed that the cumulative live birth rate after four IUI attempts from 1,641 IUI cycles was significantly lower in the teratozoospermia groups (30.32% vs. 53.22%, P<0.001) (85).”
From Isolated teratozoospermia: revisiting its relevance in male infertility: a narrative review (2024) · cites this paper as [85]
Other smaller studies observed that sperm morphology affected the outcome of IUI.
“Other studies of smaller series also observed that sperm morphology affected the outcome of IUI [86, 87, 88, 89, 90, 91, 92, 93].”
From Recommendations for Human Sperm Morphology Assessment in 2025: An Expert Review From the French BLEFCO Group (2026) · cites this paper as [87]
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The evaluation of morphological characteristics of human spermatozoa according to stricter criteria
Menkveld, R., Stander, F. S. H., Kotze, T. J. V., Kruger, T. F., & Zyl, J. A. V. (1990) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a137150 · Cited by 677 · see citing works
Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility
Guzick, D. S., Carson, S. A., Coutifaris, C., Overstreet, J. W., Factor-Litvak, P. R., Steinkampf, M. P., Hill, J. A., Mastroianni, L., Buster, J. E., Nakajima, S. T., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901213400302 · Cited by 521 · see citing works
Goverde, A. J., McDonnell, J., Vermeiden, J. P., Schats, R., Rutten, F. F., & Schoemaker, J. (2000) · The Lancet · doi:10.1016/s0140-6736(99)04002-7 · Cited by 453 · see citing works
Waart, J. V. (2001) · Human Reproduction Update · doi:10.1093/humupd/7.5.495 · Cited by 225 · see citing works
Evaluation of the relative cost-effectiveness of treatments for infertility in the UK
Philips, Z., Barraza-Lloréns, M., & Posnett, J. W. (2000) · Human Reproduction · doi:10.1093/humrep/15.1.95 · Cited by 146 · see citing works
Economic implications of assisted reproductive techniques: a systematic review
Garceau, L. (2002) · Human Reproduction · doi:10.1093/humrep/17.12.3090 · Cited by 118 · see citing works
Lindheim, S. R., Barad, D. H., Zinger, M., Witt, B. R., Amin, H. K., Cohen, B. L., Fisch, H., & Barg, P. E. (1996) · Journal of Assisted Reproduction and Genetics · doi:10.1007/bf02066610 · Cited by 49 · see citing works
Isolated teratozoospermia and intrauterine insemination
Spiessens, C., Vanderschueren, D., Meuleman, C., & D'Hooghe, T. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)01172-5 · Cited by 43 · see citing works
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Cited by
Sorted by citations
Semen quality and prediction of IUI success in male subfertility: a systematic review
Ombelet, W. U. A. M., Dhont, N., Thijssen, A., Bosmans, E., & Kruger, T. F. (2013) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2013.10.023 · Cited by 179 · see citing works
Sperm morphology: assessment, pathophysiology, clinical relevance, and state of the art in 2017
Gatimel, N., Moreau, J., Parinaud, J., & Léandri, R. D. (2017) · Andrology · doi:10.1111/andr.12389 · Cited by 172 · see citing works
Sperm Morphology: History, Challenges, and Impact on Natural and Assisted Fertility
Danis, R. B., & Samplaski, M. K. (2019) · Current Urology Reports · doi:10.1007/s11934-019-0911-7 · Cited by 81 · see citing works
Smith, R., Kovac, J., Cajipe, M., Lamb, D., & Lipshultz, L. (2017) · Asian Journal of Andrology · doi:10.4103/1008-682x.189211 · Cited by 66 · see citing works
Contemporary Management of Male Infertility
Stahl, P. J., Stember, D. S., & Goldstein, M. (2011) · Annual Review of Medicine · doi:10.1146/annurev-med-051810-101036 · Cited by 32 · see citing works
Predictive factors influencing pregnancy rates after intrauterine insemination.
Yavuz, A., Demirci, O., Sözen, H., & Uludoğan, M. (2013) · Europe PMC (PubMed Central) · Cited by 31 · see citing works
Sperm morphology and its disorders in the context of infertility
Oehninger, S., & Kruger, T. F. (2020) · F&S Reviews · doi:10.1016/j.xfnr.2020.09.002 · Cited by 34 · see citing works
Sperm morphology: Evaluating its clinical relevance in contemporary fertility practice
Pelzman, D. L., & Sandlow, J. I. (2024) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12594 · Cited by 33 · see citing works
Sun, Y., Li, B., Fan, L. Q., Zhu, W. B., Chen, X. J., Feng, J. H., Yang, C. L., & Zhang, Y. H. (2012) · Andrologia · doi:10.1111/j.1439-0272.2012.01280.x · Cited by 28 · see citing works
Isolated teratozoospermia: revisiting its relevance in male infertility: a narrative review
Atmoko, W., Savira, M., Shah, R., Chung, E., & Agarwal, A. (2024) · Translational Andrology and Urology · doi:10.21037/tau-23-397 · Cited by 23 · see citing works
“Further, another study also showed that the cumulative live birth rate after four IUI attempts from 1,641 IUI cycles was significantly lower in the teratozoospermia groups (30.32% vs. 53.22%, P 0.001) (85).”
InfluentialErdem, M., Erdem, A., Mutlu, M. F., Ozisik, S., Yildiz, S., Guler, I., & Karakaya, C. (2016) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2015.12.014 · Cited by 27 · see citing works
Zhang, E., Tao, X., Xing, W., Cai, L., & Zhang, B. (2014) · Materia Socio Medica · doi:10.5455/msm.2014.26.321-323 · Cited by 14 · see citing works
Angell, N. F., Moustafa, H. F., Rizk, B., Nawar, M. G., Rizk, C. B., Huff, C., Kennedy, R., Holland, S. B., Hazelton, J. M., García-Velasco, J. A., et al. (2008) · Cambridge University Press eBooks · doi:10.1017/cbo9780511547287.049 · Cited by 11 · see citing works
de Araújo, L. F. P., Filho, E. D. A., Fácio, C. L., Bossoni, M. C., Machado‐Paula, L. A., Corrente, J. E., Cavagna, M., Matheus, P. C., & Pontes, A. (2013) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-11-101 · Cited by 10 · see citing works
Palma, C., & vinay, B. J. I. (2014) · Revista Médica Clínica Las Condes · doi:10.1016/s0716-8640(14)70018-5 · Cited by 10 · see citing works
Fuentes Ávila, A., Blasco Sanz, R., & Cortés Alaguero, C. (2021) · Obstetrical & Gynecological Survey · doi:10.1097/ogx.0000000000000871 · Cited by 7 · see citing works
Gatimel, N., Barbotin, A., Mery, L., Beauvillard, D., Bendayan, M., Boursier, A., Boueilh, T., Pereira, B., Chammas, J., Jacquet, J., et al. (2026) · Andrology · doi:10.1111/andr.70134 · Cited by 2 · see citing works
A Study of Predictive Factors Affecting Outcome of IUI in Unexplained Infertility
Shrivastava, D. N. (2016) · Journal of Medical Science And clinical Research · doi:10.18535/jmscr/v4i2.41 · Cited by 1 · see citing works
(2006) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/01.gco.0000193023.28556.e2
- Authors
- Grigoriou, O., Pantos, K., Makrakis, E., Hassiakos, D., Konidaris, S., & Creatsas, G.
- Affiliations
- National and Kapodistrian University of Athens (GR)
- Corresponding author
- Makrakis, Evangelos
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2005-03
- Volume
- 83
- Issue
- 3
- Pages
- 773-775
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2027874894
- Cited by
- 19
- References
- 8
- Citations by year
- 2025: 1 · 2024: 2 · 2021: 1 · 2020: 1 · 2019: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 3 · 2012: 1
- FWCI
- 0.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Keywords
- teratozoospermia, intrauterine insemination, male factor infertility, semen quality, clinical pregnancy rate, live birth rate, cumulative live birth rate
- MeSH terms
- Adult, Female, Fertilization in Vitro, Humans, Infertility, Male, Insemination, Artificial, Male, Pregnancy, Pregnancy Outcome, Retrospective Studies, Spermatozoa
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