Cannflavins—From plant to patient: A scoping review

Hallmarks of Cancer: The Next Generation

Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590 · see citing works

Scoping studies: towards a methodological framework

Arksey, H., & O'Malley, L. (2005) · International Journal of Social Research Methodology · doi:10.1080/1364557032000119616 · Cited by 36,742 · see citing works

Scoping studies: advancing the methodology

Levac, D., Colquhoun, H., & O'Brien, K. K. (2010) · Implementation Science · doi:10.1186/1748-5908-5-69 · Cited by 15,268 · see citing works

Prostaglandins and Inflammation

Ricciotti, E., & FitzGerald, G. A. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.207449 · Cited by 3,852 · see citing works

Cannabis sativa: The Plant of the Thousand and One Molecules

Andre, C. M., Hausman, J.-F., & Guerriero, G. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00019 · Cited by 1,544 · see citing works

PI3K-Akt pathway: Its functions and alterations in human cancer

Osaki, M., Oshimura, M., & Ito, H. (2004) · APOPTOSIS · doi:10.1023/b:appt.0000045801.15585.dd · Cited by 1,266 · see citing works

Human Cannabinoid Pharmacokinetics

Huestis, M. A. (2007) · Chemistry & Biodiversity · doi:10.1002/cbdv.200790152 · Cited by 1,102 · see citing works

Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge

Shemer, A., Grozovski, J., Tay, T. L., Tao, J., Volaski, A., Süß, P., Ardura-Fabregat, A., Gross-Vered, M., Kim, J.-S., David, E., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-07548-5 · Cited by 1,052 · see citing works

Cannabidiol is a negative allosteric modulator of the cannabinoid CB ₁ receptor

Laprairie, R. B., Bagher, A. M., Kelly, M. E. M., & Denovan‐Wright, E. M. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13250 · Cited by 1,039 · see citing works

Flavonoid Bioavailability and Attempts for Bioavailability Enhancement

Thilakarathna, S. H., & Rupasinghe, H. P. V. (2013) · Nutrients · doi:10.3390/nu5093367 · Cited by 809 · see citing works

The pharmacology of cannabinoid receptors and their ligands: an overview

Pertwee, R. G. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803272 · Cited by 558 · see citing works

Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis

Smith, W., Urade, Y., & Jakobsson, P. (2011) · Chemical Reviews · doi:10.1021/cr2002992 · Cited by 480 · see citing works

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

Ramírez, L. V., Vodnala, S. K., Nini, R., Hunter, K. W., & Green, J. E. (2018) · Nature Communications · doi:10.1038/s41467-018-04070-6 · Cited by 433 · see citing works

Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts?

McPartland, J. M., & Russo, E. B. (2001) · Journal of Cannabis Therapeutics · doi:10.1300/j175v01n03_08 · Cited by 321 · see citing works

Defining and analyzing geoepidemiology and human autoimmunity

Shapira, Y., Agmon‐Levin, N., & Shoenfeld, Y. (2010) · Journal of Autoimmunity · doi:10.1016/j.jaut.2009.11.018 · Cited by 262 · see citing works

Pharmaceutical and biomedical analysis of cannabinoids: A critical review

Citti, C., Braghiroli, D., Vandelli, M. A., & Cannazza, G. (2017) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2017.06.003 · Cited by 254 · see citing works

Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7

Bäck, M., Powell, W. S., Dahlén, S., Drazen, J. M., Evans, J. F., Serhan, C. N., Shimizu, T., Yokomizo, T., & Rovati, G. E. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12665 · Cited by 217 · see citing works

New Methods for the Comprehensive Analysis of Bioactive Compounds in Cannabis sativa L. (hemp)

Pellati, F., Brighenti, V., Sperlea, J., Marchetti, L., Bertelli, D., & Benvenuti, S. (2018) · Molecules · doi:10.3390/molecules23102639 · Cited by 198 · see citing works

Pharmacological Foundations of Cannabis Chemovars

Lewis, M. A., Russo, E. B., & Smith, K. (2017) · Planta Medica · doi:10.1055/s-0043-122240 · Cited by 192 · see citing works

5-Lipoxygenase inhibitors: a review of recent developments and patents

Pergola, C., & Werz, O. (2010) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543771003602012 · Cited by 184 · see citing works

NMR assignments of the major cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa

Choi, Y. H., Hazekamp, A., Peltenburg-Looman, A. M. G., Frédérich, M., Erkelens, C., Lefeber, A. W. M., & Verpoorte, R. (2004) · Phytochemical Analysis · doi:10.1002/pca.787 · Cited by 165 · see citing works

The Role of Leukotrienes as Potential Therapeutic Targets in Allergic Disorders

Jo‐Watanabe, A., Okuno, T., & Yokomizo, T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143580 · Cited by 151 · see citing works

Analysis of Phenolic Compounds in Commercial Cannabis sativa L. Inflorescences Using UHPLC-Q-Orbitrap HRMS

Izzo, L., Castaldo, L., Narváez, A., Graziani, G., Gaspari, A., Rodríguez-Carrasco, Y., & Ritieni, A. (2020) · Molecules · doi:10.3390/molecules25030631 · Cited by 150 · see citing works

Non-cannabinoid constituents from a high potency Cannabis sativa variety

Radwan, M. M., ElSohly, M. A., Slade, D., Ahmed, S. A., Wilson, L., El‐Alfy, A. T., Khan, I. A., & Ross, S. A. (2008) · Phytochemistry · doi:10.1016/j.phytochem.2008.07.010 · Cited by 135 · see citing works

Cannflavins from hemp sprouts, a novel cannabinoid-free hemp food product, target microsomal prostaglandin -E2 synthase-1 and 5-lipoxygenase.

Werz, O., Seegers, J., Schaible, A. M., Weinigel, C., Barz, D., Koeberle, A., Allegrone, G., Pollastro, F., Zampieri, L., Grassi, G., et al. (2014) · PharmaNutrition · doi:10.1016/j.phanu.2014.05.001 · Cited by 131 · see citing works

Isolation and Characterization of New Cannabis Constituents from a High Potency Variety

Radwan, M. M., Ross, S. A., Slade, D., Ahmed, S. A., Zulfiqar, F., & ElSohly, M. A. (2008) · Planta Medica · doi:10.1055/s-2008-1034311 · Cited by 115 · see citing works

Biosynthesis of cannflavins A and B from Cannabis sativa L.

Rea, K. A., Casaretto, J. A., Al-Abdul-Wahid, M. S., Sukumaran, A., Geddes-McAlister, J., Rothstein, S. J., & Akhtar, T. A. (2019) · Phytochemistry · doi:10.1016/j.phytochem.2019.05.009 · Cited by 112 · see citing works

Pivotal Role of the Cyclin-dependent Kinase Inhibitor p21WAF1/CIP1 in Apoptosis and Autophagy

Fujiwara, K., Daido, S., Yamamoto, A., Kobayashi, R., Yokoyama, T., Aoki, H., Iwado, E., Shinojima, N., Kondo, Y., & Kondo, S. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611043200 · Cited by 103 · see citing works

High added-value compounds from Cannabis threshing residues

Calzolari, D., Magagnini, G., Lucini, L., Grassi, G., Appendino, G., & Amaducci, S. (2017) · Industrial Crops and Products · doi:10.1016/j.indcrop.2017.06.063 · Cited by 103 · see citing works

Pharmacokinetics and systemic endocrine effects of the phyto‐oestrogen 8‐prenylnaringenin after single oral doses to postmenopausal women

Rad, M., Humpel, M., Schaefer, O., Schoemaker, R. C., Schleuning, W. D., Cohen, A. F., & Burggraaf, J. (2006) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2006.02656.x · Cited by 99 · see citing works

Cannflavin A and B, prenylated flavones fromCannabis sativa L.

Barrett, M. L., Scutt, A. M., & Evans, F. J. (1986) · Experientia · doi:10.1007/bf02118655 · Cited by 98 · see citing works

Antileishmanial phytochemical phenolics: Molecular docking to potential protein targets

Ogungbe, I. V., Erwin, W. R., & Setzer, W. N. (2014) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2013.12.010 · Cited by 95 · see citing works

The Name of Cannabis : A Short Guide for Nonbotanists

Pollio, A. (2016) · Cannabis and Cannabinoid Research · doi:10.1089/can.2016.0027 · Cited by 94 · see citing works

In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin

Overk, C., Guo, J. P., Chadwick, L. R., Lantvit, D. D., Minassi, A., Appendino, G., Chen, S., Lankin, D. C., Farnsworth, N. R., Pauli, G. F., et al. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.06.005 · Cited by 93 · see citing works

Actions of cannabis constituents on enzymes of arachidonate metabolism: anti-inflammatory potential

EVANS, A. T., Formukong, E. A., & Evans, F. J. (1987) · Biochemical Pharmacology · doi:10.1016/0006-2952(87)90505-3 · Cited by 91 · see citing works

An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever

Powers, C. N., & Setzer, W. N. (2016) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/1386207319666160506123715 · Cited by 88 · see citing works

Isolation from cannabis sativa L. of cannflavin—a novel inhibitor of prostaglandin production

Barrett, M. L., Gordon, D., & Evans, F. J. (1985) · Biochemical Pharmacology · doi:10.1016/0006-2952(85)90325-9 · Cited by 83 · see citing works

A review on mPGES-1 inhibitors: From preclinical studies to clinical applications

Bergqvist, F., Morgenstern, R., & Jakobsson, P. (2019) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2019.106383 · Cited by 77 · see citing works

In-silico screening for anti-Zika virus phytochemicals

Byler, K., Ogungbe, I. V., & Setzer, W. N. (2016) · Journal of Molecular Graphics and Modelling · doi:10.1016/j.jmgm.2016.08.011 · Cited by 66 · see citing works

Novel cannabis flavonoid, cannflavin A displays both a hormetic and neuroprotective profile against amyloid β-mediated neurotoxicity in PC12 cells: Comparison with geranylated flavonoids, mimulone and diplacone

Eggers, C., Fujitani, M., Kato, R., & Smid, S. D. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.08.011 · Cited by 60 · see citing works

Challenges to develop novel anti‐inflammatory and analgesic drugs

Botz, B., Bölcskei, K., & Helyes, Z. (2016) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1427 · Cited by 44 · see citing works

Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer

Moreau, M., Ibeh, U., Decosmo, K., Bih, N., Yasmin‐Karim, S., Toyang, N. J., Lowe, H. I. C., & Ngwa, W. F. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.00660 · Cited by 43 · see citing works

Autophagy in breast cancer metastatic dormancy: tumor suppressing or tumor promoting functions?

Flynn, A. L. B., & Schiemann, W. P. (2019) · Journal of Cancer Metastasis and Treatment · doi:10.20517/2394-4722.2019.13 · Cited by 41 · see citing works

Microbial metabolism of cannflavin A and B isolated from Cannabis sativa

Ibrahim, A. K., Radwan, M. M., Ahmed, S. A., Slade, D., Ross, S. A., ElSohly, M. A., & Khan, I. A. (2010) · Phytochemistry · doi:10.1016/j.phytochem.2010.02.011 · Cited by 40 · see citing works

Natural Products as New Treatment Options for Trichomoniasis: A Molecular Docking Investigation

Setzer, M. C., Byler, K., Ogungbe, I. V., & Setzer, W. N. (2017) · Scientia Pharmaceutica · doi:10.3390/scipharm85010005 · Cited by 37 · see citing works

The Bibenzyl Canniprene Inhibits the Production of Pro-Inflammatory Eicosanoids and Selectively Accumulates in Some <i>Cannabis sativa</i> Strains

Allegrone, G., Pollastro, F., Magagnini, G., Taglialatela-Scafati, O., Seegers, J., Koeberle, A., Werz, O., & Appendino, G. (2017) · Journal of Natural Products · doi:10.1021/acs.jnatprod.6b01126 · Cited by 36 · see citing works

Antiparasitic Activity of C‐Geranyl Flavonoids from Mimulus bigelovii

Salem, M. M., Capers, J., Rito, S., & Werbovetz, K. A. (2011) · Phytotherapy Research · doi:10.1002/ptr.3404 · Cited by 34 · see citing works

A Regiodivergent Synthesis of Ring A C-Prenylflavones

Minassi, A., Giana, A., Ech‐Chahad, A., & Appendino, G. (2008) · Organic Letters · doi:10.1021/ol800665w · Cited by 34 · see citing works

Probing the Pharmacological Binding Properties, and Reactivity of Selective Phytochemicals as Potential HIV-1 protease Inhibitors

Akhtar, A., Hussain, W., & Rasool, N. (2019) · Universitas Scientiarum · doi:10.11144/javeriana.sc24-3.artf · Cited by 27 · see citing works

Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from Leishmania chagasi

Teixeira, B. V. F., Teles, A. L. B., da Silva, S. G., Brito, C. C. B., de Freitas, H. F., Pires, A. B. L., Froes, T. Q., & Castilho, M. S. (2019) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756366.2019.1651311 · Cited by 27 · see citing works

In Silico Computations of Selective Phytochemicals as Potential Inhibitors Against Major Biological Targets of Diabetes Mellitus

Akhtar, A., Amir, A., Hussain, W., Ghaffar, A., & Rasool, N. (2019) · Current Computer - Aided Drug Design · doi:10.2174/1573409915666190130164923 · Cited by 22 · see citing works

Extractives of Thailand cannabis: Synthesis of canniprene and isolation of new geranylated and prenylated chrysoeriols

Crombie, L., Crombie, W. M. L., & Jamieson, S. V. (1980) · Tetrahedron Letters · doi:10.1016/0040-4039(80)80248-6 · Cited by 19 · see citing works

Flavonoid-induced autophagy in hormone sensitive breast cancer cells

Brunelli, E., Pinton, G., Bellini, P., Minassi, A., Appendino, G., & Moro, L. (2009) · Fitoterapia · doi:10.1016/j.fitote.2009.04.002 · Cited by 17 · see citing works

Identification and Characterization of natural products as dual inhibitors of microsomal Prostaglandin E2 Synthase-1 and 5- Lipoxygenase

Seegers, J. (2014) · Cited by 2 · see citing works

Flavonoids are promising safe therapy against COVID-19

Alzaabi, M. M., Hamdy, R., Ashmawy, N. S., Hamoda, A. M., Alkhayat, F., Khademi, N. N., Joud, S. M. A. A., El‐Keblawy, A., & Soliman, S. S. M. (2021) · Phytochemistry Reviews · doi:10.1007/s11101-021-09759-z · Cited by 162 · see citing works

The Medicinal Natural Products of Cannabis sativa Linn.: A Review

Odieka, A. E., Obuzor, G. U., Oyedeji, O. O., Gondwe, M. M., Hosu, Y. S., & Oyedeji, A. O. (2022) · Molecules · doi:10.3390/molecules27051689 · Cited by 117 · see citing works

Cannabis: a multifaceted plant with endless potentials

Fordjour, E., Manful, C. F., Sey, A. A., Javed, R., Pham, T. H., Thomas, R., & Cheema, M. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1200269 · Cited by 106 · see citing works

The Neurotherapeutic Arsenal in Cannabis sativa: Insights into Anti-Neuroinflammatory and Neuroprotective Activity and Potential Entourage Effects

Al-Khazaleh, A. K., Zhou, X., Bhuyan, D. J., Münch, G. W., Al-Dalabeeh, E. A., Jaye, K. M., & Chang, D. (2024) · Molecules · doi:10.3390/molecules29020410 · Cited by 62 · see citing works

Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug

Procaccia, S., Lewitus, G. M., Feder, C. L., Shapira, A., Berman, P., & Meiri, D. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.894960 · Cited by 52 · see citing works

The Current and Potential Application of Medicinal Cannabis Products in Dentistry

Lowe, H. I. C., Toyang, N. J., Steele, B., Bryant, J., Ngwa, W. F., & Nedamat, K. (2021) · Dentistry Journal · doi:10.3390/dj9090106 · Cited by 45 · see citing works

Topical Use of Cannabis sativa L. Biochemicals

Mnekin, L., & Ripoll, L. (2021) · Cosmetics · doi:10.3390/cosmetics8030085 · Cited by 36 · see citing works

Current and Potential Use of Biologically Active Compounds Derived from Cannabis sativa L. in the Treatment of Selected Diseases

Bukowska, B. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312738 · Cited by 38 · see citing works

Fertilization Following Pollination Predominantly Decreases Phytocannabinoids Accumulation and Alters the Accumulation of Terpenoids in Cannabis Inflorescences

Feder, C. L., Cohen, O. M., Shapira, A., Katzir, I., Peer, R., Guberman, O., Procaccia, S., Berman, P., Flaishman, M. A., & Meiri, D. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.753847 · Cited by 36 · see citing works

Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer

Tomko, A. M., Whynot, E. G., & Dupré, D. J. (2022) · Journal of Cannabis Research · doi:10.1186/s42238-022-00151-y · Cited by 54 · see citing works

Chemistry and Biological Activities of Cannflavins of the Cannabis Plant

Abdel-Kader, M. S., Radwan, M. M., Metwaly, A. M., Eissa, I. H., Hazekamp, A., & ElSohly, M. A. (2023) · Cannabis &amp; Cannabinoid Research · doi:10.1089/can.2023.0128 · Cited by 28 · see citing works

In the weeds: A comprehensive review of cannabis; its chemical complexity, biosynthesis, and healing abilities

Laaboudi, F.-Z., Rejdali, M., Amhamdi, H., Salhi, A., Elyoussfi, A., & Ahari, M. (2024) · Toxicology Reports · doi:10.1016/j.toxrep.2024.101685 · Cited by 26 · see citing works

Phytochemical Constituents and Derivatives of Cannabis sativa; Bridging the Gap in Melanoma Treatment

Schanknecht, E., Bachari, A., Nassar, N., Piva, T. J., & Mantri, N. L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24010859 · Cited by 24 · see citing works

Exploring the Lesser-Known Bioactive Natural Products of Plant Species of the Genus Cannabis L.: Alkaloids, Phenolic Compounds, and Their Therapeutic Potential

Boucher, R., Germain, H., & Desgagné-Penix, I. (2025) · Plants · doi:10.3390/plants14091372 · Cited by 23 · see citing works

Heterologous production of Cannabis sativa-derived specialised metabolites of medicinal significance – Insights into engineering strategies

Wiles, D., Shanbhag, B. K., O’Brien, M., Doblin, M. S., Bacic, A., & Beddoe, T. (2022) · Phytochemistry · doi:10.1016/j.phytochem.2022.113380 · Cited by 21 · see citing works

The Use of Compounds Derived from Cannabis sativa in the Treatment of Epilepsy, Painful Conditions, and Neuropsychiatric and Neurodegenerative Disorders

Stasiłowicz-Krzemień, A., Nogalska, W., Maszewska, Z., Maleszka, M., Dobroń, M., Szary, A., Kępa, A., Żarowski, M., Hojan, K., Łukowicz, M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25115749 · Cited by 26 · see citing works

Entourage Effect and Analytical Chemistry: Chromatography as a Tool in the Analysis of the Secondary Metabolism of Cannabis sativa L.

Sofrás, F. M. S., & Desimone, M. F. (2022) · Current Pharmaceutical Design · doi:10.2174/1381612829666221103093542 · Cited by 16 · see citing works

Gram-Scale Preparation of Cannflavin A from Hemp (Cannabis sativa L.) and Its Inhibitory Effect on Tryptophan Catabolism Enzyme Kynurenine-3-Monooxygenase

Puopolo, T., Chang, T., Liu, C., Li, H., Liu, X., Wu, X., Ma, H., & Seeram, N. P. (2022) · Biology · doi:10.3390/biology11101416 · Cited by 13 · see citing works

Single trichome phytocannabinomics of two different cannabis varieties

Ferri, E., Cerrato, A., Caprari, C., Russo, F., Laganà, A., Capriotti, A. L., Faggiana, G., Moro, A., Citti, C., & Cannazza, G. (2025) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2025.116836 · Cited by 11 · see citing works

An Optimized Terpene Profile for a New Medical Cannabis Oil

Maggini, V., Calvi, L., Pelagatti, T., Gallo, E. R., Civati, C., Privitera, C., Squillante, F., Maniglia, P., Candia, D. D., Spampatti, R., et al. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14020298 · Cited by 11 · see citing works

Pharmacokinetics of cannabidiol, (-)-trans-Δ9-tetrahydrocannabinol, and their oxidative metabolites after intravenous and oral administration of a cannabidiol-dominant full-spectrum hemp product to beagle dogs

Kitts-Morgan, S. E., Sams, R. A., & Muir, W. W. (2025) · Frontiers in Veterinary Science · doi:10.3389/fvets.2025.1556975 · Cited by 10 · see citing works

Waste from hemp essential oil production: How distillation methods shape the byproducts value

Spinozzi, E., Boldrini, L., Ferrati, M., Betti, E., Ricciutelli, M., Zheljazkov, V. D., Dall’Acqua, S., Sut, S., Cespi, M., Petrelli, R., et al. (2025) · Industrial Crops and Products · doi:10.1016/j.indcrop.2025.121094 · Cited by 8 · see citing works

Effect of Flavonoids on MCP-1 Expression in Human Coronary Artery Endothelial Cells and Impact on MCP-1-Dependent Migration of Human Monocytes

Brüser, L., Teichmann, E., & Hinz, B. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216047 · Cited by 8 · see citing works

Antimicrobial, Probiotic, and Immunomodulatory Potential of Cannabis sativa Extract and Delivery Systems

Stasiłowicz-Krzemień, A., Szymanowska, D., Szulc, P. M., & Cielecka‐Piontek, J. (2024) · Antibiotics · doi:10.3390/antibiotics13040369 · Cited by 8 · see citing works

Computational Assessment of Cannflavin A as a TAK1 Inhibitor: Implication as a Potential Therapeutic Target for Anti-Inflammation

Chuanphongpanich, S., Racha, S., Saengsitthisak, B., Pirakitikulr, P., & Racha, K. (2023) · Scientia Pharmaceutica · doi:10.3390/scipharm91030036 · Cited by 7 · see citing works

Cannflavins isolated from Cannabis sativa impede Caenorhabditis elegans response to noxious heat

Lahaise, M., Boujenoui, F., & Beaudry, F. (2024) · Naunyn-Schmiedeberg's Archives of Pharmacology · doi:10.1007/s00210-023-02621-3 · Cited by 6 · see citing works

Tea Prepared from Dried Cannabis: What Do We Drink?

Malý, M., Beneš, F., Bínová, Z., & Hajšlová, J. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c05940 · Cited by 6 · see citing works

Cannabis: Zone Aspects of Raw Plant Components in Sport—A Narrative Review

Flangea, C., Vlad, M., Popescu, R., Dumitraşcu, V., Rață, A. L., Tryfon, M. E., Balasoiu, B., & Vlad, C. S. (2025) · Nutrients · doi:10.3390/nu17050861 · Cited by 7 · see citing works

Quality and safety assessment of hemp-based food products: Insights into seeds, flours, and oils

Malý, M., Bínová, Z., Beneš, F., & Hajšlová, J. (2025) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2025.108337 · Cited by 3 · see citing works

The Therapeutic Role of Secondary Metabolites in Neurodegenerative and Inflammatory Diseases, Mechanisms, and Potential Applications

Laadraoui, J., Kabdy, H., Oufquir, S., Aitlarradia, M., Agouram, F., Aitbaba, A., Oubella, K., & El‐Mansoury, B. (2025) · IGI Global eBooks · doi:10.4018/979-8-3693-9112-9.ch005 · Cited by 3 · see citing works

A molecular analysis in leaves of in vitro-cultivated commercial and non-commercial Cannabis sativa genotypes

Thiry, M., Sergeant, K., Cocco, E., Григорьев, С. В., Iken, M., Hausman, J.-F., Renaut, J., Lutts, S., & Guerriero, G. (2025) · Industrial Crops and Products · doi:10.1016/j.indcrop.2025.121921 · Cited by 3 · see citing works

Metabolomic and Transcriptomic Analyses Provide New Insights into Health-Promoting Metabolites from Cannabis Seeds Growing in the Bama Region of China

Duan, M., Rao, M. J., Li, Q., Zhao, F., Fan, H., Li, B., He, D., Han, S., Zhang, J., & Wang, L. (2024) · Agronomy · doi:10.3390/agronomy14040787 · Cited by 2 · see citing works

miRNA rco-MIR395a-p5_1ss8TC suppresses CsOMT957 expression leading to reduction in cannflavin A accumulation in Cannabis sativa L.

Zhou, Y., Ning, K., Chen, Y., Yang, S., Wei, X., Xu, J., Chen, S., & Dong, L. (2025) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2025.110242 · Cited by 1 · see citing works

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Formato, M., Pecoraro, M. T., Crescente, G., Piccolella, S., & Pacifico, S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-89867-6.00005-6 · Cited by 1 · see citing works

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Wanas, A. S., Radwan, M. M., Marzouk, A. A. E., Elkaeed, E. B., Alsfouk, B. A. A., Mostafa, A. E., Eissa, I. H., Metwaly, A. M., & ElSohly, M. A. (2023) · Natural Product Research · doi:10.1080/14786419.2023.2294111 · Cited by 1 · see citing works

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Peč, J., Kaczorová, D., Béreš, T., Matal, J., & Tarkowski, P. (2022) · Praktické lékárenství · doi:10.36290/lek.2022.037 · Cited by 1 · see citing works

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Pratiwi, R. A., Zuhri, M., & Oktaviani, I. (2024) · BIOTROPIA · doi:10.11598/btb.2024.31.1.1926

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Laxmi, V., & Martolia, J. (2025) · Journal of Natural Remedies · doi:10.18311/jnr/2025/47860

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Maranta, N., Martinelli, G., Fumagalli, M., Pozzoli, C., Sonzogni, E., Rossini, N., Ciriello, U., Paladino, G., Dell’Agli, M., Piazza, S., et al. (2025) · Journal of Cannabis Research · doi:10.1186/s42238-025-00335-2

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Tomko, A. M., Whynot, E. G., & Dupré, D. J. (2022) · Figshare · doi:10.6084/m9.figshare.20364218

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Bodnar, U. K. C., Villemaire-McCutcheon, J. J., Boddington, K. F., Soubeyrand, E., Al-Abdul-Wahid, M. S., Robeson, H. N., Lalonde, J., Casaretto, J. A., & Akhtar, T. A. (2026) · Journal of Cannabis Research · doi:10.1186/s42238-026-00438-4

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Boddington, K. F., Soubeyrand, E., Gelder, K. V., Perrin, C. J., Forrester, T. J. B., Holborn, J., Casaretto, J. A., Al-Abdul-Wahid, M. S., Piotrowski, M. L., Magolan, J., et al. (2026) · Journal of Natural Products · doi:10.1021/acs.jnatprod.6c00318

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Matuka, T., Oriola, A. O., Kar, P., Gondwe, M. M., Apalata, T. R., & Oyedeji, A. O. (2026) · Journal of Applied Pharmaceutical Science · doi:10.1177/22313354261436144

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Lee, S., Lee, S. B., Jung, H. J., Kim, J., Choi, H., Choi, S., & Kim, B. (2026) · Biotechnology for Biofuels and Bioproducts · doi:10.1186/s13068-026-02800-3

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Serni, E., Sobolev, A. P., Montesano, V., & D’Orazio, G. (2026) · Scientific Reports · doi:10.1038/s41598-026-59272-6

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Barrett, M. L., Scutt, A. M., & Evans, F. J. (1986) · Experientia · doi:10.1007/bf02118655 · Cited by 98 · see citing works

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Fitzpatrick, J.-M., O’Riordan, D., & Downer, E. J. (2024) · Natural Product Research · doi:10.1080/14786419.2024.2358382 · Cited by 7 · see citing works

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Chuanphongpanich, S., Racha, S., Saengsitthisak, B., Pirakitikulr, P., & Racha, K. (2023) · Scientia Pharmaceutica · doi:10.3390/scipharm91030036 · Cited by 7 · see citing works

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Holborn, J., Mooradally, A. W., Perrin, C. J., Alural, B., Aitchison, C., Borenstein, A., Jones, N., Khokhar, J. Y., Akhtar, T. A., & Lalonde, J. (2023) · Phytomedicine Plus · doi:10.1016/j.phyplu.2023.100410 · Cited by 5 · see citing works

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ElSohly, M. A., & Radwa, M. M. (2023) · Journal of Research in Pharmacy · doi:10.29228/jrp.593