Ultraviolet B irradiation induced Nrf2 degradation occurs via activation of TRPV1 channels in human dermal fibroblasts

The Pathophysiology of Mitochondrial Cell Death

Green, D. R., & Kroemer, G. (2004) · Science · doi:10.1126/science.1099320 · Cited by 3,416 · see citing works

Mitochondria as sensors and regulators of calcium signalling

Rizzuto, R., De Stefani, D., Raffaello, A., & Mammucari, C. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3412 · Cited by 1,781 · see citing works

Calcium and ROS: A mutual interplay

Görlach, A., Bertram, K., Hudecova, S., & Krizanova, O. (2015) · Redox Biology · doi:10.1016/j.redox.2015.08.010 · Cited by 1,546 · see citing works

The glamour and gloom of glycogen synthase kinase-3

Jope, R. S., & Johnson, G. V. W. (2004) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2003.12.004 · Cited by 1,522 · see citing works

The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

Bryan, H. K., Olayanju, A., Goldring, C. E., & Park, B. K. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.11.016 · Cited by 1,026 · see citing works

Regulation of Nrf2—an update

Niture, S. K., Khatri, R., & Jaiswal, A. K. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.02.008 · Cited by 873 · see citing works

Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: Progress, pitfalls, and prospects

Wardman, P. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.06.026 · Cited by 863 · see citing works

Role of antioxidants in the skin: Anti-aging effects

Masaki, H. (2010) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2010.03.003 · Cited by 788 · see citing works

SCF/β-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D., & Cuadrado, A. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.01204-10 · Cited by 759 · see citing works

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

Zhang, M., An, C., Gao, Y., Leak, R. K., Chen, J., & Zhang, F. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.09.003 · Cited by 622 · see citing works

Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis

Rada, P., Rojo, A. I., Evrard‐Todeschi, N., Innamorato, N. G., Cotte, A., Jaworski, T., Tobón-Velasco, J. C., Devijver, H., García‐Mayoral, M. F., LEUVEN, F. V., et al. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.00180-12 · Cited by 474 · see citing works

Calcineurin/NFAT signalling regulates pancreatic β-cell growth and function

Heit, J. J., Apelqvist, Å., Gu, X., Winslow, M. M., Neilson, J. R., Crabtree, G. R., & Kim, S. K. (2006) · Nature · doi:10.1038/nature05097 · Cited by 445 · see citing works

The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells

Winterbourn, C. C. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.05.004 · Cited by 420 · see citing works

The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress

Koskenkorva-Frank, T. S., Weiss, G., Koppenol, W. H., & Burckhardt, S. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.09.001 · Cited by 406 · see citing works

Mechanism of Ca2+ Activation of the NADPH Oxidase 5 (NOX5)

Bánfi, B., Tirone, F., Durussel, I., Knisz, J., Moskwa, P., Molnár, G. Z., Krause, K.-H., & Cox, J. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310268200 · Cited by 389 · see citing works

Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging

Weber, J. T., Slemmer, J. E., Shacka, J. J., & Sweeney, M. I. (2008) · Current Medicinal Chemistry · doi:10.2174/092986708783497337 · Cited by 386 · see citing works

Extracellular matrix regulation of fibroblast function: redefining our perspective on skin aging

Cole, M. A., Quan, T., Voorhees, J. J., & Fisher, G. J. (2018) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-018-0459-1 · Cited by 365 · see citing works

Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP

Cuadrado, A. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.04.029 · Cited by 265 · see citing works

UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

Moore, C., Cevikbas, F., Pasolli, H. A., Chen, Y., Kong, W., Kempkes, C., Parekh, P., Lee, S. H., Kontchou, N.-A., Yeh, I., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1312933110 · Cited by 259 · see citing works

Crosstalk between calcium and reactive oxygen species signaling in cancer

Hempel, N., & Trebak, M. (2017) · Cell Calcium · doi:10.1016/j.ceca.2017.01.007 · Cited by 243 · see citing works

NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease

Boutten, A., Goven, D., Artaud-Macari, É., Boczkowski, J., & Bonay, M. (2011) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2011.02.006 · Cited by 223 · see citing works

Activation of Dual Oxidases Duox1 and Duox2

Rigutto, S., Hoste, C., Grasberger, H., Milenkovic, M., Communi, D., Dumont, J. E., Corvilain, B., Miot, F., & De Deken, X. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m806893200 · Cited by 213 · see citing works

Reactivity of 2′,7′-dichlorodihydrofluorescein and dihydrorhodamine 123 and their oxidized forms toward carbonate, nitrogen dioxide, and hydroxyl radicals

Wrona, M., Patel, K., & Wardman, P. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.10.022 · Cited by 195 · see citing works

Nrf2-A regulator of keratinocyte redox signaling

Schäfer, M., & Werner, S. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.04.018 · Cited by 192 · see citing works

Characterization of a Cell-Lethal Product from the Photooxidation of Tryptophan: Hydrogen Peroxide

MCCORMICK, J. P., Fischer, J. R., PACHLATKO, J. P., et al. (1976) · Science · doi:10.1126/science.1108203 · Cited by 186 · see citing works

The transcription factor NF‐E2‐related Factor 2 (Nrf2): a protooncogene?

Shelton, P. M., & Jaiswal, A. K. (2012) · The FASEB Journal · doi:10.1096/fj.12-217257 · Cited by 185 · see citing works

Human Dermal Fibroblasts Produce Nitric Oxide and Express Both Constitutive and Inducible Nitric Oxide Synthase Isoforms

Wang, R., Ghahary, A., Shen, Y. J., Scott, P. G., & Tredget, E. E. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12343428 · Cited by 167 · see citing works

Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases

Deschamps, J. D., Kenyon, V. A., & Holman, T. R. (2006) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2006.01.057 · Cited by 165 · see citing works

Cytochrome c Is a Potent Catalyst of Dichlorofluorescin Oxidation: Implications for the Role of Reactive Oxygen Species in Apoptosis

Burkitt, M. J., & Wardman, P. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.4578 · Cited by 154 · see citing works

Induction of bystander effects by UVA, UVB, and UVC radiation in human fibroblasts and the implication of reactive oxygen species

Wideł, M., Krzywon, A., Gajda, K., Skonieczna, M., & Rzeszowska‐Wolny, J. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.12.021 · Cited by 150 · see citing works

Preparation and Practical Applications of 2′,7′-Dichlorodihydrofluorescein in Redox Assays

Reiniers, M. J., van Golen, R. F., Bonnet, S. A., Broekgaarden, M., van Gulik, T. M., Egmond, M. R., & Heger, M. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00043 · Cited by 144 · see citing works

UV light phototransduction activates transient receptor potential A1 ion channels in human melanocytes

Bellono, N. W., Kammel, L. G., Zimmerman, A. L., & Oancea, E. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215555110 · Cited by 140 · see citing works

Direct Detection of Singlet Oxygen Generated by UVA Irradiation in Human Cells and Skin

Baier, J., Maisch, T., Maier, M., Landthaler, M., & Bäumler, W. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700741 · Cited by 137 · see citing works

The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases

Rhodes, L. E., Gledhill, K., Masoodi, M., Haylett, A. K., Brownrigg, M., Thody, A. J., Tobin, D. J., & Nicolaou, A. (2009) · The FASEB Journal · doi:10.1096/fj.09-136077 · Cited by 118 · see citing works

Baicalein protects Human melanocytes from H2O2-induced apoptosis via inhibiting mitochondria-dependent caspase activation and the p38 MAPK pathway

Liu, B., Jian, Z., Li, Q., Li, K., Wang, Z., Liu, L., Tang, L., Yi, X., Wang, H., Li, C., et al. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.04.015 · Cited by 114 · see citing works

Spinal 12-lipoxygenase-derived hepoxilin A 3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptors

Gregus, A. M., Doolen, S., Dumlao, D. S., Buczynski, M. W., Takasusuki, T., Fitzsimmons, B., Hua, X., Taylor, B. K., Dennis, E. A., & Yaksh, T. L. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1110460109 · Cited by 112 · see citing works

The molecular mechanism of rotenone-induced α-synuclein aggregation: Emphasizing the role of the calcium/GSK3β pathway

Yuan, Y., Yan, W.-F., Sun, J., Huang, J., Mu, Z., & Chen, N. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2014.11.029 · Cited by 111 · see citing works

Oxidative stress mediated Ca2+ release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells

Farrukh, M. R., Nissar, U.-A., Afnan, Q., Rafiq, R. A., Sharma, L., Amin, S., Kaiser, P. J., Sharma, P. R., & Tasduq, S. A. (2014) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2014.03.005 · Cited by 100 · see citing works

Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways

Farfariello, V., Amantini, C., & Santoni, G. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0312123 · Cited by 77 · see citing works

The role of TRPV1 channel in aged human skin

Lee, Y. M., Kang, S. M., & Chung, J. H. (2012) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2011.11.003 · Cited by 73 · see citing works

Ultraviolet Radiation-Induced Production of Nitric Oxide:A multi-cell and multi-donor analysis

Holliman, G., Lowe, D., Cohen, H., Felton, S. J., & Raj, K. (2017) · Scientific Reports · doi:10.1038/s41598-017-11567-5 · Cited by 64 · see citing works

Activation of GSK3β/β-TrCP axis via PHLPP1 exacerbates Nrf2 degradation leading to impairment in cell survival pathway during diabetic nephropathy

Mathur, A., Pandey, V. K., & Kakkar, P. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.04.550 · Cited by 60 · see citing works

DNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survival

Tu, Y., Ji, C., Yang, B., Yang, Z., Gu, H., Lu, C., Wang, R., Su, Z., Chen, B., Sun, W., et al. (2013) · Molecular Cancer · doi:10.1186/1476-4598-12-172 · Cited by 59 · see citing works

NRF2-targeted therapeutics: New targets and modes of NRF2 regulation

de la Vega, M. R., Dodson, M. B., Chapman, E., & Zhang, D. D. (2016) · Current Opinion in Toxicology · doi:10.1016/j.cotox.2016.10.005 · Cited by 55 · see citing works

EGFR activation confers protections against UV-induced apoptosis in cultured mouse skin dendritic cells

Cao, C., Lü, S., Jiang, Q. L., Wang, W., Song, X., Kivlin, R., Wallin, B., Bagdasarian, A., Tamakloe, T., & Chu, W. (2008) · Cellular Signalling · doi:10.1016/j.cellsig.2008.06.010 · Cited by 40 · see citing works

A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway

Pang, T., Wang, Y., Gao, Y., et al. (2016) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.3 · Cited by 40 · see citing works

Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling

Guidarelli, A., Fiorani, M., Cerioni, L., & Cantoni, O. (2018) · Redox Biology · doi:10.1016/j.redox.2018.10.015 · Cited by 38 · see citing works

Dibenzoylmethane Protects Against CCl4-Induced Acute Liver Injury by Activating Nrf2 via JNK, AMPK, and Calcium Signaling

Cao, M., Wang, H., Guo, L., Yang, S., Liu, C., Khor, T. O., Yu, S., & Kong, A. T. (2017) · The AAPS Journal · doi:10.1208/s12248-017-0133-1 · Cited by 32 · see citing works

Baicalein inhibits matrix metalloproteinase 1 expression via activation of TRPV 1‐Ca‐ ERK pathway in ultraviolet B–irradiated human dermal fibroblasts

Huang, K., Ma, K., Chang, Y., Lo, L., Jhap, T., Su, Y., Liu, P., & Chueh, S. (2019) · Experimental Dermatology · doi:10.1111/exd.13912 · Cited by 30 · see citing works

Melatonin induces calcium mobilization and influences cell proliferation independently of MT1/MT2 receptor activation in rat pancreatic stellate cells

Santofimia‐Castaño, P., Garcia-Sanchez, L., Ruy, D. C., Sánchez-Correa, B., Fernández‐Bermejo, M., Tarazona, R., Salido, G. M., & González, A. (2015) · Cell Biology and Toxicology · doi:10.1007/s10565-015-9297-6 · Cited by 27 · see citing works

ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia

Buendía, I., Tenti, G., Michalska, P., Méndez‐López, I., Luengo, E., Satriani, M., Padín, J. F., López, M. G., Ramos, M. T., Garcı́a, A. G., et al. (2016) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.6b00181 · Cited by 27 · see citing works

Sirtuin 1 inhibits TNF-α-mediated osteoclastogenesis of bone marrow-derived macrophages through both ROS generation and TRPV1 activation

Yan, S., Miao, L.-J., Lu, Y.-H., & Wang, L.-Z. (2018) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-018-3477-7 · Cited by 27 · see citing works

Inhibition of Renin Release by Arachidonic Acid Metabolites, 12(s)-HPETE and 12-HETE: Role of TRPV1 Channels

Xie, C., & Wang, D. H. (2011) · Endocrinology · doi:10.1210/en.2011-0141 · Cited by 23 · see citing works

Ultraviolet B irradiation increases keratin 1 and keratin 10 expressions in HaCaT keratinocytes via TRPV 1 activation and ERK phosphorylation

Huang, K., Ma, K., Liu, P., et al. (2017) · Experimental Dermatology · doi:10.1111/exd.13292 · Cited by 22 · see citing works

Increased Biosynthesis of Lipoxygenase Products by UVB-Irradiated Guinea Pig Epidermis: Evidence of a Cyclooxygenase Inhibitor

Burrall, B. A., & Ziboh, V. A. (1986) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12275653 · Cited by 15 · see citing works

Metal Allergens Induce Nitric Oxide Production by Mouse Dermal Fibroblasts via the Hypoxia-Inducible Factor-2α–Dependent Pathway

Kuroishi, T., Bando, K., Endo, Y., & Sugawara, S. (2013) · Toxicological Sciences · doi:10.1093/toxsci/kft142 · Cited by 15 · see citing works

Human Antigen R-mediated mRNA Stabilization Is Required for Ultraviolet B-induced Autoinduction of Amphiregulin in Keratinocytes

Nakayama, H., Fukuda, S., Matsushita, N., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.417527 · Cited by 14 · see citing works

In Vitro Study of Isoflavones and Isoflavans as Potent Inhibitors of Human 12‐ and 15‐Lipoxygenases

Mascayano, C., Espinosa, V., Sepúlveda‐Boza, S., et al. (2013) · Chemical Biology & Drug Design · doi:10.1111/cbdd.12157 · Cited by 12 · see citing works

The contribution of TRPV1 channel to 20-HETE—Aggravated ischemic neuronal injury

Zhang, X., Demerdash, N. E., Falck, J. R., et al. (2018) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2018.07.001 · Cited by 11 · see citing works

A new copper ionophore DPMQ protects cells against ultraviolet B irradiation by inhibiting the TRPV1 channel

Huang, K., Ma, K., Hung, Y., Lo, L., Lin, K., Liu, P., Hu, M., & Chueh, S. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26861 · Cited by 9 · see citing works

Boosting the Photoaged Skin: The Potential Role of Dietary Components

Geng, R., Kang, S.-G., Huang, K., & Tong, T. (2021) · Nutrients · doi:10.3390/nu13051691 · Cited by 116 · see citing works

Partially interacted phosphorylation/dephosphorylation trees extracted from signaling pathways in cells

Liu, J., & Shimohara, K. (2007) · Artificial Life and Robotics · doi:10.1007/s10015-006-0413-9

Effect of Heparin on Aggregation and Phosphorylation of Human Neuronal tau Protein

He, R. (1999) · Zhongguo shengwu huaxue yu fenzi shengwu xuebao

Some characteristics of phosphorylation and dephosphorylation of proteins of isolated rat liver nuclei.

Szeszák, F. (1976) · PubMed · Cited by 2 · see citing works

Controlling β-Sheet Assembly in Genetically Engineered Silk by Enzymatic Phosphorylation/Dephosphorylation

Winkler, S., Wilson, D. L., & Kaplan, D. L. (2000) · Biochemistry · doi:10.1021/bi001335w · Cited by 124 · see citing works

Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5

Liu, F., Zaidi, T., Iqbal, K., Grundke, I., & Gong, C. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00510-9 · Cited by 106 · see citing works