Cited by 161Atrial Fibrillation Management and OutcomesAcute Ischemic Stroke ManagementCardiovascular and Diving-Related Complications

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Asymptomatic versus symptomatic atrial fibrillation: A systematic review of age/gender differences and cardiovascular outcomes

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Xiong, Qinmei, Proietti, Marco, Senoo, Keitaro, Lip, Gregory Y.H.·2015·International Journal of Cardiology

DOI 10.1016/j.ijcard.2015.05.011

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Abstract

Up to 40% of atrial fibrillation (AF) patients are asymptomatic. Despite this, scarce data are available about asymptomatic AF, with regard to its clinical profile and relationship to cerebrovascular and cardiovascular risks. Our objective was to conduct a systematic review and meta-analysis was to study the relationship between age and gender with asymptomatic AF and to establish whether patients with asymptomatic AF have a higher risk of death (all-cause and cardiovascular) and stroke/systemic thromboembolism, when compared to symptomatic AF patients. After a comprehensive search, 6 studies (2 randomized clinical trials and 4 observational studies) were entered in the meta-analysis. Despite significant heterogeneity, our data show that the prevalence of females amongst asymptomatic AF group was significantly less compared to the symptomatic AF group (RR, 0.57; 95% CI: 0.52-0.64). No difference in age between asymptomatic and symptomatic AF patients (P=0.72) was seen. No differences were found in all-cause death between patients with asymptomatic and symptomatic AF (RR, 1.38; 95% CI: 0.82-2.17), nor in cardiovascular death (RR, 0.85; 95% CI: 0.53-1.36) or stroke/thromboembolism (RR, 1.72 95% CI: 0.59-5.08). Asymptomatic AF is more associated with male sex, irrespective of age. Both general and cardiovascular death risks as well as thromboembolic risk do not seem to be affected by the asymptomatic clinical status. Symptomatic status should not determine our approach to stroke prevention and other cardiovascular prevention therapies, amongst patients with AF.

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Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., & Singer, D. E. (2001) · JAMA · doi:10.1001/jama.285.18.2370 · Cited by 6,205
Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., de Ferranti, S., Després, J.-P., Fullerton, H. J., Howard, V. J., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000152 · Cited by 5,797
HEART DISEASE AND STROKE STATISTICS–2014 UPDATE: A REPORT FROM THE AMERICAN HEART ASSOCIATION
Tarver, T. (2014) · Journal of Consumer Health on the Internet · doi:10.1080/15398285.2014.902284 · Cited by 5,595
Cryptogenic stroke and underlying atrial fibrillation
Sanna, T., Diener, H.-C., Passman, R. S., Di Lazzaro, V., Bernstein, R. A., Morillo, C. A., Rymer, M. M., Thijs, V., Rogers, T., Beckers, F., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1313600 · Cited by 2,161
Atrial Fibrillation and the Risk of Myocardial Infarction
Soliman, E. Z., Safford, M. M., Muntner, P., Khodneva, Y. A., Dawood, F. Z., Zakai, N. A., Thacker, E. L., Judd, S. E., Howard, V. J., Howard, G., et al. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.11912 · Cited by 471
Gender-Related Differences in Presentation, Treatment, and Outcome of Patients With Atrial Fibrillation in Europe
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Boriani, G., Laroche, C., Diemberger, I., Fantecchi, E., Popescu, M. I., Rasmussen, L. H., Sinagra, G., Petrescu, L., Tavazzi, L., Maggioni, A. P., et al. (2014) · The American Journal of Medicine · doi:10.1016/j.amjmed.2014.11.026 · Cited by 344
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Asymptomatic atrial fibrillation: demographic features and prognostic information from the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study
Flaker, G. C., Belew, K., Beckman, K., Vidaillet, H., Kron, J., Safford, R., Mickel, M., & Barrell, P. (2005) · American Heart Journal · doi:10.1016/j.ahj.2004.06.032 · Cited by 341
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Show all 23 references

Research works printed but not linked: 1

Anon. Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions — Methods Guide — Chapter|AHRQ Effective Health Care Program.

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Authors: Xiong, Q., Proietti, M., Senoo, K., & Lip, G. Y. H.
Affiliations: Birmingham City Hospital (GB)
Corresponding author: Proietti, Marco
ORCID: Xiong, Qinmei
Proietti, Marco
Senoo, Keitaro
Lip, Gregory Y.H.
Venue: International Journal of Cardiology
Publisher: Elsevier BV
Published: 2015-07
Volume: 191
Pages: 172-177
ISSN: 0167-5273 (ISSN-L)
DOI: 10.1016/j.ijcard.2015.05.011
OpenAlex: W1496114842
Cited by: 161
References: 23
Citations by year: 2026: 9 · 2025: 10 · 2024: 15 · 2023: 7 · 2022: 14 · 2021: 28 · 2020: 15 · 2019: 21 · 2018: 7 · 2017: 17 · 2016: 14 · 2015: 4
FWCI: 2.40
Type: journal article
Language: en
Open access: green
research.birmingham.ac.uk
Licence: other-oa
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: International Journal of Cardiology (publishedVersion)
PubMed (publishedVersion)
IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
University of Birmingham Research Portal (University of Birmingham) (submittedVersion, other-oa)
VBN Forskningsportal (Aalborg Universitet) (submittedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
Keywords: asymptomatic atrial fibrillation, symptomatic atrial fibrillation, sex differences, age differences, all-cause mortality, cardiovascular mortality, stroke, systemic thromboembolism, stroke prevention, cardiovascular risk
MeSH terms: Age Factors, Atrial Fibrillation, Female, Humans, Male, Sex Characteristics, Randomized Controlled Trials as Topic, Treatment Outcome, Asymptomatic Diseases, Observational Studies as Topic

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Asymptomatic versus symptomatic atrial fibrillation: A systematic review of age/gender differences and cardiovascular outcomes

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