Extra information about treatment is too much for the patient with psychosis
Abstract
Background Case law across jurisdictions requires ever more complete disclosure of material facts when obtaining consent to treatment.Aims To determine whether giving extra information impairs the mental capacity to make decisions about treatment.Method The MacCAT-T, MacCAT-FP, PANSS and GAF were administered to 88 detained forensic patients with psychosis. Two positive and two negative facts were given about each of two anti-psychotic drugs, and no treatment (twelve items). A choice was elicited. The criterion for incompetence was inability to express a choice. Two extra positive and two extra negative facts about each of the three options were given (twelve extra items) and a choice was again elicited, while repeating the MacCAT-T.Results Giving extra information led to a decline in the total score on the MacCAT-T. Twenty one were initially unable to make a choice (24%). After additional information, 33 were incapable (37.5%, Chi-squared p<0.001). Those initially incapable had the lowest scores on all measures of functional capacity and GAF, with highest scores for symptoms. Those able to choose a treatment option had the highest levels of function and least symptoms. Those who became incapable had intermediate scores.Conclusions Giving extra information made an extra 15% unable to choose. Clinical judgement must be exercised concerning the amount of information disclosed. Deciding what is material to the individual is arbitrary when so few items of information can be processed. Greater use of guardianship and independent second opinions is recommended.
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The proportion unable to express a choice increased to 37.5% if more information was given.
“increasing to 37.5% (95% CI [27 -48%]) if more information was given (Kennedy et al., 2009).”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Kennedy et al., 2009
Around 25% of patients were unable to express a choice between two medications or no treatment.
“Regarding the ability to decide between two medications or no treatment, around 25% of patients were unable to express a choice (Dornan et al., 2015;Kennedy et al., 2009;Rutledge et al., 2008)”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Kennedy et al., 2009
Positive symptoms were found to be associated with incapacity in 8 studies, especially conceptual disorganization, manic symptoms, delusions and unusual thought content.
“Positive symptoms were found to be associated with incapacity in 8 studies (Dornan et al., 2015;Fraguas et al., 2007;Kennedy et al., 2009;Mandarelli et al., 2018b;G. Owen et al., 2009;Skipworth et al., 2013;Spencer et al., 2018), especially conceptual disorganization (G.Owen et al., 2009;Skipworth et al., 2013), manic symptoms (Mandarelli et al., 2014(Mandarelli et al., , 2018b;;Spencer et al., 2”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Kennedy et al., 2009
Being able to express a choice was significantly associated with better global functioning, lower positive symptoms and overall psychopathology.
“Through nonparametric analysis, being able to express a choice was also significantly associated with better global functioning (Kennedy et al., 2009;Rutledge et al., 2008), as well as lower positive symptoms and overall psychopathology (Kennedy et al., 2009;Rutledge et al., 2008).”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Kennedy et al., 2009
Low global functioning predicted incapacity in four studies.
“Finally, low global functioning predicted incapacity in four studies (Dornan et al., 2015;Kennedy et al., 2009;Rutledge et al., 2008;Tor et al., 2020).”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Kennedy et al., 2009
Six studies analyzed the relationship between psychopathological and cognitive variables with the different subscales of the MacCAT.
“Six studies analyzed the relationship between psychopathological and cognitive variables with the different subscales of the MacCAT (Bilanakis et al., 2013;Kennedy et al., 2009;Mandarelli et al., 2014Mandarelli et al., , 2018b;;Rutledge et al., 2008;Seo et al., 2011).”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Kennedy et al., 2009
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378 · see citing works
Diagnostic and Statistical Manual of Mental Disorders.
Widiger, T. A. (2000) · Oxford University Press eBooks · doi:10.1037/10518-009 · Cited by 19,767 · see citing works
Comprehensive Textbook of Psychiatry
Freedman, A. M., & Kaplan, H. I. (1967) · The American Journal of the Medical Sciences · doi:10.1097/00000441-196712000-00052 · Cited by 3,818 · see citing works
Kaplan & Sadock's Comprehensive Textbook of Psychiatry
Sadock, B. J., & Sadock, V. A. (2000) · Cited by 1,523 · see citing works
Assessing patients' capacities to consent to treatment
Appelbaum, P. S., & Grisso, T. (1988) · New England Journal of Medicine · doi:10.1056/nejm198812223192504 · Cited by 1,399 · see citing works
Assessing Competence to Consent to Treatment: A Guide for Physicians and Other Health Prefessionals
Grisso, T., & Appelbaum, P. S. (1998) · doi:10.1093/oso/9780195103724.001.0001 · Cited by 823 · see citing works
The MacCAT-T: a clinical tool to assess patients' capacities to make treatment decisions
(1997) · Psychiatric Services · doi:10.1176/ps.48.11.1415 · Cited by 704 · see citing works
Tests of competency to consent to treatment
Roth, L. H., Meisel, A., & Lidz, C. W. (1977) · American Journal of Psychiatry · doi:10.1176/ajp.134.3.279 · Cited by 662 · see citing works
Explaining risks: turning numerical data into meaningful pictures
Edwards, A., Elwyn, G. J., & Mulley, A. G. (2002) · BMJ · doi:10.1136/bmj.324.7341.827 · Cited by 645 · see citing works
Mental capacity in psychiatric patients: Systematic review
Okai, D., Owen, G., McGuire, H., Singh, S., Churchill, R., & Hotopf, M. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.035162 · Cited by 262 · see citing works
Comparison of standards for assessing patients' capacities to make treatment decisions
Grisso, T., & Appelbaum, P. S. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.7.1033 · Cited by 250 · see citing works
Personal paper: Risk language and dialects
Calman, S. K. C., & Royston, G. (1997) · BMJ · doi:10.1136/bmj.315.7113.939 · Cited by 222 · see citing works
Owen, G. S., Richardson, G., David, A. S., Szmukler, G., Hayward, P., & Hotopf, M. (2008) · BMJ · doi:10.1136/bmj.39580.546597.be · Cited by 172 · see citing works
Assessing Competence to Consent to Treatment
Hoffman, B. F. (1980) · The Canadian Journal of Psychiatry · doi:10.1177/070674378002500427 · Cited by 165 · see citing works
Competence to refuse treatment in anorexia nervosa
Tan, J., Hope, T., & Stewart, A. (2003) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2003.09.010 · Cited by 150 · see citing works
Prat, C. S., Keller, T. A., & Just, M. A. (2007) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2007.19.12.1950 · Cited by 142 · see citing works
Reliability of mental capacity assessments in psychiatric in-patients
Cairns, R., Maddock, C., Buchanan, A., David, A. S., Hayward, P., Richardson, G., Szmukler, G., & Hotopf, M. (2005) · British Journal of Psychiatry · doi:10.1192/bjp.187.4.372 · Cited by 135 · see citing works
The Maudsley 2005-2006 Prescribing Guidelines
(2005) · CRC Press eBooks · doi:10.1201/b14455 · Cited by 131 · see citing works
Re T (Adult: Refusal of Medical Treatment)
(1992) · PubMed · Cited by 123 · see citing works
The MacArthur adjudicative competence study: Development and validation of a research instrument.
Hoge, S. K., Bonnie, R. J., Poythress, N. G., Monahan, J. T., Eisenberg, M. M., & Feucht-Haviar, T. (1997) · Law and Human Behavior · doi:10.1023/a:1024826312495 · Cited by 116 · see citing works
Marson, D. C. (2005) · Schizophrenia Bulletin · doi:10.1093/schbul/sbj027 · Cited by 84 · see citing works
Assessment of competence to complete advance directives: validation of a patient centred approach
Fazel, S., Hope, T., & Jacoby, R. (1999) · BMJ · doi:10.1136/bmj.318.7182.493 · Cited by 83 · see citing works
Mental health law: civil liberties and the principle of reciprocity
Eastman, N. (1994) · BMJ · doi:10.1136/bmj.308.6920.43 · Cited by 82 · see citing works
Functional mental capacity is not independent of the severity of psychosis
Rutledge, E., Kennedy, M., O'Neill, H., & Kennedy, H. G. (2008) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2007.11.002 · Cited by 44 · see citing works
Self-citationAkinkunmi, A. (2002) · PubMed · Cited by 43 · see citing works
O’Neill, C., Sinclair, H., Kelly, A., & Kennedy, H. G. (2002) · Irish Journal of Psychological Medicine · doi:10.1017/s0790966700006959 · Cited by 32 · see citing works
Self-citationMental disorder ethics: theory and empirical investigation
Eastman, N., & Starling, B. (2006) · Journal of Medical Ethics · doi:10.1136/jme.2005.013276 · Cited by 23 · see citing works
Testing two methods of presenting side effect risk information about common medicines
Knapp, P., Berry, D. C., & Raynor, D. K. (2001) · International Journal of Pharmacy Practice · doi:10.1111/j.2042-7174.2001.tb01066.x · Cited by 17 · see citing works
Hughes, G. (1962) · BMJ · doi:10.1136/bmj.1.5271.114 · Cited by 10 · see citing works
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Lepping, P., Stanly, T., & Turner, J. (2015) · Clinical Medicine · doi:10.7861/clinmedicine.15-4-337 · Cited by 110 · see citing works
Naughton, M., Nulty, A., Abidin, Z., Davoren, M., O’Dwyer, S., & Kennedy, H. G. (2012) · BMC Research Notes · doi:10.1186/1756-0500-5-302 · Cited by 62 · see citing works
Self-citationLarkin, A., & Hutton, P. (2017) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.116.193458 · Cited by 57 · see citing works
Dornan, J., Kennedy, M., Garland, J., Rutledge, E., & Kennedy, H. G. (2015) · BMC Research Notes · doi:10.1186/s13104-015-1547-4 · Cited by 29 · see citing works
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Kontos, N. J., Querques, J., & Freudenreich, O. (2014) · Psychosomatics · doi:10.1016/j.psym.2014.11.004 · Cited by 28 · see citing works
Pons, E. V., Salvador‐Carulla, L., Calcedo‐Barba, A., Paz, S., Messer, T., Pacciardi, B., & Zeller, S. L. (2020) · Health Science Reports · doi:10.1002/hsr2.179 · Cited by 23 · see citing works
Kennedy, H. G., Mullaney, R., McKenna, P. F., Thompson, J., Timmons, D., Gill, P., O’Sullivan, O. P., Braham, P., Duffy, D. M., Kearns, A., et al. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02912-6 · Cited by 20 · see citing works
Self-citationMarcó-García, S., Ariyo, K., Owen, G. S., & David, A. S. (2024) · Psychological Medicine · doi:10.1017/s0033291724000242 · Cited by 18 · see citing works
Buizza, C., Strozza, C., Sbravati, G., de Girolamo, G., Ferrari, C., Iozzino, L., Macis, A., Kennedy, H. G., & Candini, V. (2022) · Annals of General Psychiatry · doi:10.1186/s12991-022-00413-2 · Cited by 13 · see citing works
Self-citationMoynihan, G., O’Reilly, K., O’Connor, J., & Kennedy, H. G. (2018) · BMC Psychiatry · doi:10.1186/s12888-018-1658-2 · Cited by 13 · see citing works
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van der Plas, E., David, A. S., & Fleming, S. M. (2019) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2019.101504 · Cited by 11 · see citing works
Assessment of decision-making autonomy in chronic pain patients: a pilot study
d’Ussel, M., Sacco, E., Moreau, N., Nizard, J., & Durand, G. (2024) · BMC Medical Ethics · doi:10.1186/s12910-024-01096-y · Cited by 10 · see citing works
Koukopoulos, A. E., Mandarelli, G., Maglio, G., Macellaro, M., Cifrodelli, M., Kotzalidis, G. D., Tarsitani, L., Biondi, M., & Ferracuti, S. (2020) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2020.100037 · Cited by 6 · see citing works
Marcó-García, S., Guilera, G., Ferrer-Quintero, M., Ochoa, S., Escuder-Romeva, G., Martínez-Mondejar, A., Montalbán-Roca, V., Cacho, N. D., Rubio‐Abadal, E., Escanilla-Casal, A., et al. (2023) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2023.101874 · Cited by 5 · see citing works
Marazia, C., Rucci, P., Fangerau, H., Voßberg, D., Rolfes, V., Iozzino, L., Iommi, M., Gosek, P., Heitzman, J., Ferrari, C., et al. (2022) · Schizophrenia Bulletin Open · doi:10.1093/schizbullopen/sgac037 · Cited by 4 · see citing works
Davoren, M., O’Reilly, K., Mohan, D. J., & Kennedy, H. G. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-058581 · Cited by 2 · see citing works
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Corrigan, M. (2019) · Arrow@dit (Dublin Institute of Technology)
Expertise, Structured Professional Judgement and Risk Assessment
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Buizza, C., Strozza, C., Sbravati, G., de Girolamo, G., Ferrari, C., Iozzino, L., Macis, A., Kennedy, H. G., & Candini, V. (2022) · Figshare · doi:10.6084/m9.figshare.21077622
Self-citationBuizza, C., Strozza, C., Sbravati, G., de Girolamo, G., Ferrari, C., Iozzino, L., Macis, A., Kennedy, H. G., & Candini, V. (2022) · Figshare · doi:10.6084/m9.figshare.21077616
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Self-citationBuizza, C., Strozza, C., Sbravati, G., de Girolamo, G., Ferrari, C., Iozzino, L., Macis, A., Kennedy, H. G., & Candini, V. (2022) · Figshare · doi:10.6084/m9.figshare.21077610
Self-citationKennedy, H. G., Mullaney, R., McKenna, P. F., Thompson, J., Timmons, D., Gill, P., O’Sullivan, O. P., Braham, P., Duffy, D. M., Kearns, A., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13142152
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Self-citation
- Authors
- Kennedy, M., Dornan, J., Rutledge, E., O'Neill, H., & Kennedy, H. G.
- Affiliations
- Central Mental Hospital (IE)
- Trinity College Dublin (IE)
- Corresponding author
- Kennedy, Harry G.
- ORCID
- Kennedy, Harry G.
- Venue
- International Journal of Law and Psychiatry
- Publisher
- Elsevier BV
- Published
- 2009-11
- Volume
- 32
- Issue
- 6
- Pages
- 369-376
- ISSN
- 0160-2527 (ISSN-L)
- OpenAlex
- W2038488309
- Cited by
- 29
- References
- 30
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 8 · 2021: 1 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 1 · 2015: 2 · 2014: 1 · 2012: 1
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Law and Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Lenus, The Irish Health Repository (Dr Steevens Hospital Library) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Healthcare Decision-Making and Restraints
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Ethics and Legal Issues in Pediatric Healthcare
- Keywords
- informed consent, treatment refusal, decision-making capacity, psychosis, forensic psychiatric patients, antipsychotic drugs, guardianship, second opinion, functional capacity
- MeSH terms
- Adult, Choice Behavior, Commitment of Persons with Psychiatric Disorders, Decision Making, Female, Humans, Informed Consent, Ireland, Male, Patient Education as Topic, Patient Participation, Psychiatric Status Rating Scales, Psychotic Disorders, Schizophrenia, Schizophrenic Psychology, Mental Competency, Treatment Outcome, Disclosure, Comprehension
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