Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

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Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor

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Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment

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NK CELL RECEPTORS

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Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells

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Tumor-infiltrating Tim-3 + T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk

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Donor-specific hypo-responsiveness occurs in simultaneous liver-kidney transplant recipients after the first year

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Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting

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Restoration of T Cell function in multi-drug resistant bacterial sepsis after interleukin-7, anti-PD-L1, and OX-40 administration

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A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis

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Astragalus polysaccharide ameliorates CD8+ T cell dysfunction through STAT3/Gal-3/LAG3 pathway in inflammation‐induced colorectal cancer

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Molecular characterization of HCMV‐specific immune responses: Parallels between CD8+ T cells, CD4+ T cells, and NK cells

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Immunotherapeutic effects of IL-7 during a chronic viral infection in mice

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Ageing and latent CMV infection impact on maturation, differentiation and exhaustion profiles of T-cell receptor gammadelta T-cells

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Adenoviral vaccination combined with CD40 stimulation and CTLA-4 blockage can lead to complete tumor regression in a murine melanoma model

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Impact of CD4 T cells on intratumoral CD8 T-cell exhaustion and responsiveness to PD-1 blockade therapy in mouse brain tumors

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Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response

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Antiviral NK cell responses in HIV infection: II. viral strategies for evasion and lessons for immunotherapy and vaccination

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Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation

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Exhausted CD8 T Cells Downregulate the IL-18 Receptor and Become Unresponsive to Inflammatory Cytokines and Bacterial Co-infections

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Mouse PVRIG Has CD8+ T Cell–Specific Coinhibitory Functions and Dampens Antitumor Immunity

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Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients

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The Role of Metabolic Dysfunction in T-Cell Exhaustion During Chronic Viral Infection

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Elevated expression of Tim-3 on CD8 T cells correlates with disease severity of pulmonary tuberculosis

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Integrating Genomic Signatures for Immunologic Discovery

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MEK inhibitors selectively suppress alloreactivity and graft-versus-host disease in a memory stage-dependent manner

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Loss of DNAM‐1 contributes to CD8+ T‐cell exhaustion in chronic HIV‐1 infection

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Quality of the Transgene-Specific CD8+ T Cell Response Induced by Adenoviral Vector Immunization Is Critically Influenced by Virus Dose and Route of Vaccination

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Sprouty-2 regulates HIV-specific T cell polyfunctionality

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Lymphocytic Alveolitis Is Associated with the Accumulation of Functionally Impaired HIV-Specific T Cells in the Lung of Antiretroviral Therapy–Naive Subjects

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Transcription factor regulation of CD8+ T‐cell memory and exhaustion

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The Microbiome, Systemic Immune Function, and Allotransplantation

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Signals that drive T follicular helper cell formation

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Harnessing the Effects of BTKi on T Cells for Effective Immunotherapy against CLL

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Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer

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Helpless Priming Sends CD8+ T Cells on the Road to Exhaustion

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Self-reactivity controls functional diversity of naive CD8+ T cells by co-opting tonic type I interferon

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Rgs16 promotes antitumor CD8 + T cell exhaustion

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Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy

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Technology meets TILs: Deciphering T cell function in the -omics era

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Massively parallel knock-in engineering of human T cells

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Targeting ROS-sensing Nrf2 potentiates anti-tumor immunity of intratumoral CD8+ T and CAR-T cells

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Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate

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Adaptive immunity to Anaplasma pathogens and immune dysregulation: Implications for bacterial persistence

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LAG3 (CD223) and autoimmunity: Emerging evidence

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Mechanisms Governing Immunotherapy Resistance in Pancreatic Ductal Adenocarcinoma

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Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion

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T‐cell exhaustion interrelates with immune cytolytic activity to shape the inflamed tumor microenvironment

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Stem cell like memory T cells: A new paradigm in cancer immunotherapy

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Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control

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Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii

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Myeloid-Derived Suppressor Cells in Murine Retrovirus-Induced AIDS Inhibit T- and B-Cell ResponsesIn VitroThat Are Used To Define the Immunodeficiency

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Distinctive features of CD4+ T cell dysfunction in chronic viral infections

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CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8 + T EM and CD8 + T RM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease

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Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models

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CD244 represents a new therapeutic target in head and neck squamous cell carcinoma

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EBV-Specific CD8+ T Cells from Asymptomatic Pediatric Thoracic Transplant Patients Carrying Chronic High EBV Loads Display Contrasting Features: Activated Phenotype and Exhausted Function

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Mitochondrial respiration is necessary for CD8+ T cell proliferation and cell fate

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Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases

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Virus-Specific Immune Response in HBeAg-Negative Chronic Hepatitis B: Relationship with Clinical Profile and HBsAg Serum Levels

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Pathway-GPS and SIGORA: identifying relevant pathways based on the over-representation of their gene-pair signatures

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Advances in targeting co‐inhibitory and co‐stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy

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Cutting Edge: 2B4-Mediated Coinhibition of CD4+ T Cells Underlies Mortality in Experimental Sepsis

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Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment

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Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells

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Use of Mass Cytometry to Profile Human T Cell Exhaustion

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Hepatitis B

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Galectin-1 Tunes TCR Binding and Signal Transduction to Regulate CD8 Burst Size

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Phenotyping of immune and endometrial epithelial cells in endometrial carcinomas revealed by single-cell RNA sequencing

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Common Themes in Zoonotic Spillover and Disease Emergence: Lessons Learned from Bat- and Rodent-Borne RNA Viruses

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Follicular Helper T Cells Promote Liver Pathology in Mice during Schistosoma japonicum Infection

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Independent evolution of Fc‐ and Fab‐mediated HIV‐1‐specific antiviral antibody activity following acute infection

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Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models

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CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

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Immunometabolism: A new target for improving cancer immunotherapy

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