Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection

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Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation

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Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans

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Enhancing Virus-Specific Immunity In Vivo by Combining Therapeutic Vaccination and PD-L1 Blockade in Chronic Hepadnaviral Infection

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PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity

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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy

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Not-so-opposite ends of the spectrum: CD8+ T cell dysfunction across chronic infection, cancer and autoimmunity

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Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes

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PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer

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Inhibitory Receptors Beyond T Cell Exhaustion

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Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity

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Phenotype, Function, and Gene Expression Profiles of Programmed Death-1hi CD8 T Cells in Healthy Human Adults

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Cellular metabolism regulates the differentiation and function of T-cell subsets

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VEGF-A drives TOX-dependent T cell exhaustion in anti–PD-1–resistant microsatellite stable colorectal cancers

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Molecular and Cellular Functions of CTLA-4

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The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment

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Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

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Global DNA Methylation Remodeling Accompanies CD8 T Cell Effector Function

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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer

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Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection

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IL10 and PD-1 Cooperate to Limit the Activity of Tumor-Specific CD8+ T Cells

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