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A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus
Open accessAbstract
The analysis of patient blood transcriptional profiles offers a means to investigate the immunological mechanisms relevant to human diseases on a genome-wide scale. In addition, such studies provide a basis for the discovery of clinically relevant biomarker signatures. We designed a strategy for microarray analysis that is based on the identification of transcriptional modules formed by genes coordinately expressed in multiple disease data sets. Mapping changes in gene expression at the module level generated disease-specific transcriptional fingerprints that provide a stable framework for the visualization and functional interpretation of microarray data. These transcriptional modules were used as a basis for the selection of biomarkers and the development of a multivariate transcriptional indicator of disease progression in patients with systemic lupus erythematosus. Thus, this work describes the implementation and application of a methodology designed to support systems-scale analysis of the human immune system in translational research settings.
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“By contrast, various blood disorders have been shown to correlate with extreme values for the major vectors of modules of gene expression92.”
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Golub, T. R., Slonim, D. K., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J. P., Coller, H., Loh, M. L., Downing, J. R., Caligiuri, M. A., et al. (1999) · Science · doi:10.1126/science.286.5439.531 · Cited by 11,516
Harary, F. (1969) · Cited by 10,739
Mootha, V. K., Lindgren, C. M., Eriksson, K.-F., Subramanian, A., Sihag, S., Lehar, J., Puigserver, P., Carlsson, E., Ridderstråle, M., Laurila, E., et al. (2003) · Nature Genetics · doi:10.1038/ng1180 · Cited by 10,197
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Alizadeh, A. A., Eisen, M. B., Davis, R. E., Ma, C., Lossos, I. S., Rosenwald, A., Boldrick, J. C., Sabet, H., Tran, T., Yu, X., et al. (2000) · Nature · doi:10.1038/35000501 · Cited by 9,925
Fitzmaurice, G. M., Laird, N. M., & Ware, J. H. (2011) · Wiley Series in Probability and Statistics · doi:10.1002/9781119513469 · Cited by 4,639
Derivation of the sledai. A disease activity index for lupus patients
Bombardier, C., Gladman, D. D., Urowitz, M. B., Caron, D., Chang, C. H., Austin, A., Bell, A., Bloch, D. A., Corey, P. N., Decker, J. L., et al. (1992) · Arthritis & Rheumatism · doi:10.1002/art.1780350606 · Cited by 4,570
Linear Mixed Models for Longitudinal Data
Verbeke, G. (1997) · Lecture Notes in Statistics · doi:10.1007/978-1-4612-2294-1_3 · Cited by 3,506
Baechler, E. C., Batliwalla, F., Karypis, G., Gaffney, P. M., Ortmann, W. A., Espe, K. J., Shark, K. B., Grande, W. J., Hughes, K. M. H., Kapur, V., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337679100 · Cited by 2,246
MAQC Consortium, Shi, L., Shi, L., Reid, L. H., Jones, W. D., Shippy, R., Warrington, J. A., Baker, S. C., Collins, P. J., de Longueville, F., et al. (2006) · Nature Biotechnology · doi:10.1038/nbt1239 · Cited by 2,126
Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood
Bennett, L. B., Palucka, K., Arce, E., Cantrell, V., Borvák, J., Banchereau, J., & Pascual, V. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20021553 · Cited by 1,990
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Germain, R. N. (2010) · Immunity · doi:10.1016/j.immuni.2010.09.014 · Cited by 99
Esmail, H., Lai, R., Lesosky, M., Wilkinson, K. A., Graham, C. M., Horswell, S. D., Coussens, A. K., Barry, C. E., O’Garra, A., & Wilkinson, R. J. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1711853115 · Cited by 97
Tuller, T., Atar, S., Ruppin, E., Gurevich, M., & Achiron, A. (2012) · Genes and Immunity · doi:10.1038/gene.2012.55 · Cited by 98
Aranow, C. B., Kamen, D. L., Dall’Era, M., Massarotti, E. M., Mackay, M. C., Koumpouras, F., Coca, A., Chatham, W. W., Clowse, M. E. B., Criscione‐Schreiber, L. G., et al. (2015) · Arthritis & Rheumatology · doi:10.1002/art.39108 · Cited by 98
Fernández, R. R., Tapia, L. I., Yang, C., Torres, J. P., Chávez‐Bueno, S., García, C., Jaramillo, L., Moore‐Clingenpeel, M., Jafri, H. S., Peeples, M. E., et al. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix543 · Cited by 100
Self-citationKarakaslar, E. O., Katiyar, N., Hasham, M., Youn, A., Sharma, S., Chung, C., Marches, R., Korstanje, R., Banchereau, J., & Ucar, D. (2023) · Aging Cell · doi:10.1111/acel.13792 · Cited by 98
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Liu, C., & Ahearn, J. M. (2009) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2009.01.008 · Cited by 97
Joosten, S. A., Fletcher, H. A., & Ottenhoff, T. H. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0073230 · Cited by 95
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Banchereau, R., Cepika, A., Banchereau, J., & Pascual, V. (2017) · Annual Review of Immunology · doi:10.1146/annurev-immunol-051116-052225 · Cited by 98
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Tsang, J. S. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.06.005 · Cited by 94
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Chiche, L., Forel, J.-M., Thomas, G., Farnarier, C., Vely, F., Bléry, M., Papazian, L., & Vivier, É. (2011) · BioMed Research International · doi:10.1155/2011/986491 · Cited by 92
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Ahearn, J. M., Liu, C., Kao, A. H., & Manzi, S. (2012) · Translational research · doi:10.1016/j.trsl.2012.01.021 · Cited by 90
Chen, P.-M., Katsuyama, E., Satyam, A., Li, H., Rubio, J., Jung, S., Andrzejewski, S., Becherer, J. D., Tsokos, M., Abdi, R., et al. (2022) · Science Advances · doi:10.1126/sciadv.abo4271 · Cited by 86
Barnes, M., Grom, A. A., Thompson, S. D., Griffin, T. A., Luyrink, L. K., Colbert, R. A., & Glass, D. N. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27657 · Cited by 90
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Dufour, A., Bellac, C., Eckhard, U., Solis, N., Klein, T., Kappelhoff, R., Fortelny, N., Jobin, P., Rozmus, J., Mark, J., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04717-4 · Cited by 79
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Park, J., Munagala, I. D., Xu, H., Blankenship, D., Maffucci, P., Chaussabel, D., Banchereau, J., Pascual, V., & Cunningham‐Rundles, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074893 · Cited by 87
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Catalina, M. D., Bachali, P., Geraci, N., Grammer, A. C., & Lipsky, P. E. (2019) · Communications Biology · doi:10.1038/s42003-019-0382-x · Cited by 87
Kong, X., Worley, L., Rinchai, D., Bondet, V., Jithesh, P. V., Goulet, M., Nonnotte, E., Rebillat, A. S., Conte, M., Mircher, C., et al. (2020) · Journal of Clinical Immunology · doi:10.1007/s10875-020-00803-9 · Cited by 86
Self-citationSystems Immunology: Learning the Rules of the Immune System
Villani, A., Sarkizova, S., & Hacohen, N. (2018) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042617-053035 · Cited by 89
Ardura, M. I., Banchereau, R., Mejías, A., Pucchio, T. D., Glaser, C., Allantaz, F., Pascual, V., Banchereau, J., Chaussabel, D., & Ramilo, O. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005446 · Cited by 85
Self-citationJudson, M. A., Marchell, R., Mascelli, M. A., Piantone, A., Barnathan, E. S., Petty, K. J., Chen, D., Fan, H., Grund, H., Ma, K., et al. (2011) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2011.06.017 · Cited by 85
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Li, S., Todor, A., & Luo, R. (2015) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2015.10.005 · Cited by 86
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rd, J. W., & Domaszewska, T. (2016) · doi:10.7287/peerj.preprints.2420v1 · Cited by 79
Baron, D., Ramstein, G., Chesneau, M., Echasseriau, Y., Pallier, A., Paul, C., Degauque, N., Hernández-Fuentes, M. P., Fueyo, A. S., Newell, K. A., et al. (2015) · Kidney International · doi:10.1038/ki.2014.395 · Cited by 84
Duan, M., Nguyen, D. C., Joyner, C. J., Saney, C. L., Tipton, C. M., Andrews, J., Lonial, S., Kim, C. M., Hentenaar, I., Kosters, A., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112682 · Cited by 85
Wu, J., Ekman, C. J., Jönsen, A., Sturfelt, G. K., Bengtsson, A. A., Gottsäter, A., Lindblad, B., Lindqvist, E., Saxne, T., & Dahlbäck, B. (2011) · Arthritis Research & Therapy · doi:10.1186/ar3316 · Cited by 83
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Brunner, H. I., Huggins, J., & Klein‐Gitelman, M. S. (2011) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2011.15 · Cited by 81
Taguchi, Y., & Murakami, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0066714 · Cited by 80
Jourde‐Chiche, N., Whalen, E., Gondouin, B., Speake, C., Gersuk, V. H., Dussol, B., Burtey, S., Pascual, V., Chaussabel, D., & Chiche, L. (2016) · Rheumatology · doi:10.1093/rheumatology/kew439 · Cited by 79
Self-citationCao, R. G., Suárez, N. M., Obermoser, G., Lopez, S. M. C., Flaño, E., Mertz, S. E., Albrecht, R. A., García‐Sastre, A., Mejías, A., Xu, H., et al. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu079 · Cited by 79
Self-citationGao, L., Bird, A., Meednu, N., Dauenhauer, K., Liesveld, J. L., Anolik, J. H., & Looney, R. J. (2017) · Arthritis & Rheumatology · doi:10.1002/art.40142 · Cited by 80
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Altman, M. C., Rinchai, D., Baldwin, N. E., Toufiq, M., Whalen, E., Garand, M., Kabeer, B. S. A., Alfaki, M., Presnell, S., Khaenam, P., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24584-w · Cited by 69
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Li, H., Han, Z., Sun, Y., Wang, F., Hu, P., Gao, Y., Bai, X., Peng, S., Ren, C., Xu, X., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50426-6 · Cited by 73
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Price, J. D., & Tarbell, K. V. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00288 · Cited by 73
Bacchetta, R., Gregori, S., Serafini, G., Sartirana, C., Schulz, U., Zino, E., Tomiuk, S., Jansen, U., Ponzoni, M., Paties, C. T., et al. (2010) · Haematologica · doi:10.3324/haematol.2010.025825 · Cited by 69
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Nishi, H., & Mayadas, T. N. (2018) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000577 · Cited by 64
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Ahn, S. H., Tsalik, E. L., Cyr, D. D., Zhang, Y., van Velkinburgh, J. C., Langley, R. J., Glickman, S. W., Cairns, C. B., Zaas, A. K., Rivers, E. P., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0048979 · Cited by 61
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Tan, Y. Q., Tamayo, P., Nakaya, H. I., Pulendran, B., Mesirov, J. P., & Haining, W. N. (2013) · European Journal of Immunology · doi:10.1002/eji.201343657 · Cited by 62
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Cepika, A., Banchereau, R., Segura, É., Ohouo, M., Cantarel, B. L., Göller, K., Cantrell, V., Ruchaud, E., Gatewood, E., Nguyen, P., et al. (2017) · The Journal of Experimental Medicine · doi:10.1084/jem.20170412 · Cited by 59
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Clancy, R. M., Halushka, M. K., Rasmussen, S. E., Lhakhang, T. W., Chang, M., & Buyon, J. P. (2018) · The Journal of Immunology · doi:10.4049/jimmunol.1800357 · Cited by 59
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Banchereau, R., Baldwin, N. E., Cepika, A., Athale, S., Xue, Y., Yu, C. I., Metang, P., Cheruku, A., Berthier, I., Gayet, I., et al. (2014) · Nature Communications · doi:10.1038/ncomms6283 · Cited by 62
Self-citationSin, D. D., Hollander, Z., DeMarco, M. L., McManus, B. M., & Ng, R. T. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201505-0871pp · Cited by 59
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Self-citationMo, A., Marigorta, U. M., Arafat, D., Chan, L. H. K., Ponder, L. A., Jang, S. R., Prince, J., Kugathasan, S., Prahalad, S., & Gibson, G. C. (2018) · Genome Medicine · doi:10.1186/s13073-018-0558-x · Cited by 58
Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD
Harris, P., Sridhar, S., Peng, R., Phillips, J. E., Cohn, R. G., Burns, L. B., Woods, J., Ramanujam, M., Loubeau, M., Tyagi, G., et al. (2012) · Mucosal Immunology · doi:10.1038/mi.2012.86 · Cited by 58
the BCG study team, Fletcher, H. A., Filali‐Mouhim, A., Nemes, E., Hawkridge, A., Keyser, A. T., Njikan, S., Hatherill, M., Scriba, T. J., Abel, B., et al. (2016) · BMC Medicine · doi:10.1186/s12916-016-0617-3 · Cited by 54
Integrating Genomic Signatures for Immunologic Discovery
Haining, W. N., & Wherry, E. J. (2010) · Immunity · doi:10.1016/j.immuni.2010.02.001 · Cited by 55
Nakaya, H. I., & Pulendran, B. (2011) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0b013e32834dc37b · Cited by 53
OʼHanlon, T. P., Rider, L. G., Gan, L., Fannin, R. D., Paules, R. S., Umbach, D. M., Weinberg, C. R., Shah, R., Mav, D., Gourley, M. F., et al. (2011) · Arthritis Research & Therapy · doi:10.1186/ar3330 · Cited by 54
A 380-gene meta-signature of active tuberculosis compared with healthy controls
Blankley, S., Graham, C. M., Levin, J., Turner, J., Berry, M. P. R., Bloom, C. I., Xu, Z., Pascual, V., Banchereau, J., Chaussabel, D., et al. (2016) · European Respiratory Journal · doi:10.1183/13993003.02121-2015 · Cited by 51
Self-citationHerman, P. E., Stein, A., Gibbs, K., Korsunsky, I., Gregersen, P. K., & Bloom, O. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2017.5519 · Cited by 56
Angarola, B. L., Sharma, S. M., Katiyar, N., Kang, H. G., Nehar-Belaid, D., Park, S., Gott, R., Eryilmaz, G. N., LaBarge, M. A., Palucka, K., et al. (2024) · Nature Aging · doi:10.1038/s43587-024-00751-8 · Cited by 58
Oswald, M., Curran, M. E., Lamberth, S. L., Townsend, R. M., Hamilton, J. D., Chernoff, D., Carulli, J. P., Townsend, M. J., Weinblatt, M. E., Kern, M., et al. (2014) · Arthritis & Rheumatology · doi:10.1002/art.38947 · Cited by 53
IRF5 genetic risk variants drive myeloid-specific IRF5 hyperactivation and presymptomatic SLE
Li, D., Matta, B., Song, S., Nelson, V. L., Diggins, K. E., Simpfendorfer, K. R., Gregersen, P. K., Linsley, P. S., & Barnes, B. J. (2019) · JCI Insight · doi:10.1172/jci.insight.124020 · Cited by 53
Garaud, J. C., Schickel, J., Blaison, G., Knapp, A., Dembélé, D., Ruer‐Laventie, J., Korganow, A., Martin, T., Soulas-Sprauel, P., & Pasquali, J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023900 · Cited by 52
T Cell Transcriptomes Describe Patient Subtypes in Systemic Lupus Erythematosus
Bradley, S. J., Suárez‐Fueyo, A., Moss, D. R., Kyttaris, V. C., & Tsokos, G. C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141171 · Cited by 52
Integrated, multicohort analysis reveals unified signature of systemic lupus erythematosus
Haynes, W. A., Haddon, D. J., Diep, V. K., Khatri, A., Bongen, E., Yiu, G., Balboni, I., Bolen, C. R., Mao, R., Utz, P. J., et al. (2020) · JCI Insight · doi:10.1172/jci.insight.122312 · Cited by 53
Maertzdorf, J., Weiner, J. M., & Kaufmann, S. H. E. (2012) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.12.0246 · Cited by 50
Quakkelaar, E. D., Redeker, A., Haddad, E. K., Harari, A., McCaughey, S. M., Duhen, T., Filali-Mouhim, A., Goulet, J.-P., Loof, N. M., OSSENDORP, F. A., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016819 · Cited by 50
Immune Profiling and Precision Medicine in Systemic Lupus Erythematosus
Nagafuchi, Y., Shoda, H., & Fujio, K. (2019) · Cells · doi:10.3390/cells8020140 · Cited by 49
Harnessing Dendritic Cells to Generate Cancer Vaccines
Palucka, K., Ueno, H., Fay, J. W., & Banchereau, J. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05000.x · Cited by 52
Self-citationArtyomov, M. N., Munk, A., Gorvel, L., Korenfeld, D., Cella, M., Tung, T., & Klechevsky, E. (2015) · The Journal of Experimental Medicine · doi:10.1084/jem.20131675 · Cited by 48
Systems-Level Analysis of Innate Immunity
Zak, D. E., Tam, V. C., & Aderem, A. A. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120254 · Cited by 49
Fletcher, S. P., Chin, D. J., Cheng, D. T., Ravindran, P., Bitter, H., Gruenbaum, L. M., Côté, P. J., Ma, H., Klumpp, K., & Menne, S. (2012) · Hepatology · doi:10.1002/hep.25954 · Cited by 49
Metadata
- Authors
- Chaussabel, D., Quinn, C., Shen, J., Patel, P., Glaser, C., Baldwin, N., Stichweh, D., Blankenship, D., Li, L., Munagala, I., Bennett, L., Allantaz, F., Mejias, A., Ardura, M., Kaizer, E., Monnet, L., Allman, W., Randall, H., Johnson, D., Lanier, A., Punaro, M., Wittkowski, K. M., White, P., Fay, J., Klintmalm, G., Ramilo, O., Palucka, A. K., Banchereau, J., & Pascual, V.
- Affiliations
- National Institute of Allergy and Infectious Diseases (US)
- Baylor University (US)
- Baylor Scott & White Health (US)
- Children's Medical Center (US)
- Rockefeller University (US)
- Corresponding author
- Chaussabel, Damien
- Banchereau, Jacques
- ORCID
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2008-07
- Volume
- 29
- Issue
- 1
- Pages
- 150-164
- ISSN
- 1074-7613 (ISSN-L)
- PMC
- PMC2727981
- OpenAlex
- W2150932450
- Cited by
- 649
- References
- 49
- Citations by year
- 2026: 21 · 2025: 18 · 2024: 25 · 2023: 30 · 2022: 26 · 2021: 50 · 2020: 40 · 2019: 42 · 2018: 42 · 2017: 32 · 2016: 46 · 2015: 47 · 2014: 37 · 2013: 52 · 2012: 41
- FWCI
- 13.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Immunity (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Public Health Service (U19 AIO57234-02, R01 I068842)
- National Cancer Institute (P01CA084512, R01CA078846)
- National Institute of Allergy and Infectious Diseases (U19AI057234, R01AI068842)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR050770, P50AR055503, P50AR054083)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene expression and cancer classification
- Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioinformatics and Genomic Networks
- Keywords
- systemic lupus erythematosus, transcriptional modules, gene expression profiling, microarray data analysis, biomarker discovery, immune system, blood transcriptome
- MeSH terms
- Adolescent, Child, Female, Humans, Lupus Erythematosus, Systemic, Male, Disease Progression, Computational Biology, Oligonucleotide Array Sequence Analysis, Gene Expression Profiling, Genomics
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