Cited by 317Gut microbiota and healthMetabolomics and Mass Spectrometry StudiesOral microbiology and periodontitis research

The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.

Finding the Missing Links among Metabolites, Microbes, and the Host

Open access

Abstract

The unexpected diversity of the human microbiome and metabolome far exceeds the complexity of the human genome. Although we now understand microbial taxonomic and genetic repertoires in some populations, we are just beginning to assemble the necessary computational and experimental tools to understand the metabolome in comparable detail. However, even with the limited current state of knowledge, individual connections between microbes and metabolites, between microbes and immune function, and between metabolites and immune function are being established. Here, we provide our perspective on these connections and outline a systematic research program that could turn these individual links into a broader network that allows us to understand how these components interact. This program will enable us to exploit connections among the microbiome, metabolome, and host immune system to maintain health and perhaps help us understand how to reverse the processes that lead to a wide range of immune and other diseases.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.immuni.2014.05.015

Cites

76 of 76 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 76 references

Cited by

Sorted by citations

Items 101–200 of 317

Metadata

Authors
Dorrestein, P. C., Mazmanian, S. K., & Knight, R.
Affiliations
  • University of California San Diego (US)
  • California Institute of Technology (US)
  • Howard Hughes Medical Institute (US)
Corresponding author
Knight, Rob
Venue
Immunity
Publisher
Elsevier BV
Published
2014-06
Volume
40
Issue
6
Pages
824-832
ISSN
1074-7613 (ISSN-L)
OpenAlex
W2056978288
Cited by
317
References
76
Citations by year
2026: 8 · 2025: 17 · 2024: 32 · 2023: 29 · 2022: 27 · 2021: 30 · 2020: 38 · 2019: 28 · 2018: 21 · 2017: 22 · 2016: 28 · 2015: 26 · 2014: 11
FWCI
11.88
Type
journal article
Language
en
Open access
Locations
  • Immunity (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • CaltechAUTHORS (California Institute of Technology) (submittedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • Howard Hughes Medical Institute
  • National Institute of Mental Health (R01MH100556)
  • National Human Genome Research Institute (U01HG004866, R01HG004872)
  • National Institute of Diabetes and Digestive and Kidney Diseases (R01DK078938, P01DK078669)
  • National Institute of Neurological Disorders and Stroke (R01NS085910)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolomics and Mass Spectrometry Studies
  • Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Keywords
human microbiome, human metabolome, host-microbe interactions, microbial metabolites, host immune function, microbial diversity, immune disorders, metabolomics
MeSH terms
Bacterial Proteins, Humans, Gastrointestinal Tract, Metagenome, Metabolome, Microbiota

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review