Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer

Wing, James B., Tanaka, Atsushi, Sakaguchi, Shimon·2019·Immunity

DOI 10.1016/j.immuni.2019.01.020

Cited by (730)

Items 301–400 of 730

Protein phosphatase 6 (Pp6) is crucial for regulatory T cell function and stability in autoimmunity
Wei Cai, Junxun Zhang, Hong Zhou, Xiangxiao Li, Fangzhou Lou, Yang Sun, Zhenyao Xu, Jing Bai, Qianqian Yin, Zhikai Wang et al. · 2021 · Genes & Diseases
The functional roles of m6A modification in T lymphocyte responses and autoimmune diseases
Huimin Zhou, Lingxiang Mao, Huaxi Xu, Shengjun Wang, Jie Tian · 2022 · Cytokine & Growth Factor Reviews
FOXP3 and SQSTM1/P62 correlate with prognosis and immune infiltration in hepatocellular carcinoma
Shuohui Liu, Honglong Zhang, Jun Yan, Jun Wei Zhu, Zhongtian Bai, Xun Li · 2022 · Pathology - Research and Practice
Bifidobacteria shape antimicrobial T-helper cell responses during infancy and adulthood
Katrin Vogel, Aditya Arra, Holger Lingel, Dirk Bretschneider, Florian Prätsch, Denny Schanze, Martin Zenker, Silke Balk, Dunja Bruder, Robert Geffers et al. · 2023 · Nature Communications
A tumor-associated heparan sulfate-related glycosaminoglycan promotes the generation of functional regulatory T cells
Leticia Martín‐Cruz, Marcos Viñuela, Ioanna Kalograiaki, Alba Angelina, Paola Oquist-Phillips, Irene Real-Arévalo, Francisco Javier Cañada, José Ignacio Tudela, Luis M. Moltó, Jesús Moreno Sierra et al. · 2023 · Cellular and Molecular Immunology
TNFR2 signalling in inflammatory diseases
Richard O. Williams, Felix I. L. Clanchy, Yi-Shu Huang, Wen-Yi Tseng, Trevor W. Stone · 2024 · Best Practice & Research Clinical Rheumatology
Targeting CXCR4 impaired T regulatory function through PTEN in renal cancer patients
Sara Santagata, Giuseppina Rea, Anna Maria Bello, Anna Capiluongo, M. Napolitano, Sonia Desicato, A. Fragale, C. D'Alterio, A. Trotta, C. Ieranò et al. · 2024 · British Journal of Cancer
Novel insights: crosstalk with non-puerperal mastitis and immunity
Yao Zhou, Jie Gong, Xianguang Deng, Lele Shen, Lifang Liu · 2024 · Frontiers in Immunology
JunB Controls Intestinal Effector Programs in Regulatory T Cells
Joshua D. Wheaton, Maria Ciofani · 2020 · Frontiers in Immunology
Tolerogenic vaccines: Targeting the antigenic and cytokine niches of FOXP3+ regulatory T cells
Mark D. Mannie, Kayla B. DeOca, Alexander G. Bastian, Cody D. Moorman · 2020 · Cellular Immunology
Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function
Aiting Wang, Mengdi Yang, Rui Liang, Fangming Zhu, Fuxiang Zhu, Xinnan Liu, Yichao Han, Ruirong Lin, Xiaoxia Wang, Dan Li et al. · 2020 · Frontiers in Immunology
Identification of senescence-associated long non-coding RNAs to predict prognosis and immune microenvironment in patients with hepatocellular carcinoma
Chengzhi Gao, Guangming Zhou, Min Cheng, Lan Feng, Pengbo Cao, Gangqiao Zhou · 2022 · Frontiers in Genetics
Discovery of Novel 3-Phenylpiperidine Derivatives Targeting the β-Catenin/B-Cell Lymphoma 9 Interaction as a Single Agent and in Combination with the Anti-PD-1 Antibody for the Treatment of Colorectal Cancer
Hao Zhang, Chenglong Liu, Qiushi Chen, Lian Shen, Wenting Xiao, Jiayi Li, Yonghui Wang, Di Zhu, Qingwei Zhang, Jianqi Li · 2023 · Journal of Medicinal Chemistry
Zfp335 establishes eTreg lineage and neonatal immune tolerance by targeting Hadha-mediated fatty acid oxidation
Xin Wang, Lina Sun, Biao Yang, Wenhua Li, Cangang Zhang, Xiaofeng Yang, Yae Sun, Xiaonan Shen, Yang Gao, Bomiao Ju et al. · 2023 · Journal of Clinical Investigation
Cell-type-specific molecular characterization of cells from circulation and kidney in IgA nephropathy with nephrotic syndrome
Qilin Chen, Huimin Jiang, Rong Ding, Jinjie Zhong, Longfei Li, Junli Wan, Xiaoqian Feng, Liping Peng, Xia Yang, Han Chen et al. · 2023 · Frontiers in Immunology
Off-label use of Baricitinib improves moderate and severe atopic dermatitis in China through inhibiting MAPK and PI3K/Akt/mTOR pathway via targeting JAK-STAT signaling of CD4+ cells
Shuang Chen, Caihua Li, Zeng Tu, Tao Cai, Xinying Zhang, Lei Wang, Ruoyuan Tian, Jinglan Huang, Yuxuan Gong, Xiaotong Yang et al. · 2024 · Frontiers in Pharmacology
Lymphatic endothelial cell-mediated accumulation of CD177 + Treg cells suppresses antitumor immunity in human esophageal squamous cell carcinoma
Min Ma, Liang Li, Shu-Han Yang, Chuan Huang, Weitao Zhuang, Shujie Huang, Xin Xia, Yong Tang, Zijun Li, Zhi-Bin Zhao et al. · 2024 · OncoImmunology
Preclinical development of a novel CCR8/CTLA-4 bispecific antibody for cancer treatment by disrupting CTLA-4 signaling on CD8 T cells and specifically depleting tumor-resident Tregs
Cuicui Guo, Xiaodong Dai, Yulei Du, Xiumei Xiong, Xun Gui · 2024 · Cancer Immunology Immunotherapy
Dual-engineered Treg-Exosome-IKVAV nanovesicles spatiotemporally sequentially regulate neuro-immune microenvironment to promote spinal cord injury repair
Xin‐Jin Su, Gu Changjiang, Feihui Zeng, Ziheng Wei, Kong Qingjie, Sun WeiJin, Zhu Chao, Xiongsheng Chen · 2026 · Journal of Nanobiotechnology
CaMK4 promotes abortion‐related Th17 cell imbalance by activating AKT/mTOR signaling pathway
Shuo Chang, Tailang Yin, Fan He, Jinli Ding, Ye Shang, Jing Yang · 2020 · American Journal of Reproductive Immunology
The Effect of Intratumoral Interrelation among FOXP3+ Regulatory T Cells on Treatment Response and Survival in Triple-Negative Breast Cancer
Noriko Goda, Chika Nakashima, Ichiro Nagamine, Sunao Otagaki · 2022 · Cancers
Treatment of EAE Mice with Treg, G-MDSC and IL-2: a New Insight into Cell Therapy for Multiple Sclerosis
Mohammad Mehdi Ghorbani, Touraj Farazmandfar, Saeid Abediankenari, Hadi Hassannia, Zahra Maleki, Majid Shahbazi · 2022 · Immunotherapy
Single-cell RNA sequencing reveals the suppressive effect of PPP1R15A inhibitor Sephin1 in antitumor immunity
Rongjing Wang, Yuchao Zhang, Shiwei Guo, Siyu Pei, Wei Mei Guo, Zhenchuan Wu, Hailong Wang, Minghui Wang, Yizhe Li, Yufei Zhu et al. · 2023 · iScience
Autoimmunity: A New Focus on Nasal Polyps
Jingyu Huang, Yu Xu · 2023 · International Journal of Molecular Sciences
Unraveling the tumor immune microenvironment of lung adenocarcinoma using single-cell RNA sequencing
Lele Song, Yuan Gong, Erpeng Wang, Jianchun Huang, Yuemin Li · 2024 · Therapeutic Advances in Medical Oncology
Immunotherapies targeting the oncogenic fusion gene CLDN18-ARHGAP in gastric cancer
Yue Wang, Hanbing Wang, Tao Shi, Xueru Song, Xin Zhang, Yue Zhang, Xuan Wang, Keying Che, Yuting Luo, Lixia Yu et al. · 2024 · EMBO Molecular Medicine
Advances in the Study of CD8+ Regulatory T Cells
Xiaolei Tang, Vipin Kumar · 2019 · Critical Reviews in Immunology
Organized immune cell interactions within tumors sustain a productive T-cell response
Maria Andrea Cardenas, Nataliya Prokhnevska, Haydn Thomas Kissick · 2020 · International Immunology
A novel immune-related prognostic signature in epithelial ovarian carcinoma
Tong Su, Panpan Zhang, Fujun Zhao, Shu Zhang · 2021 · Aging
Standing Variations Modeling Captures Inter-Individual Heterogeneity in a Deterministic Model of Prostate Cancer Response to Combination Therapy
Harsh Vardhan Jain, Inmaculada C. Sorribes, Samuel K. Handelman, Johnna Barnaby, Trachette Levon Jackson · 2021 · Cancers
A deficient MIF-CD74 signaling pathway may play an important role in immunotherapy-induced hyper-progressive disease
Jiahui Wang, Jinsheng Hong, Feiyu Yang, Fangming Liu, Xiangdong Wang, Zan Shen, Duojiao Wu · 2021 · Cell Biology and Toxicology
Reconstitution of the immune system and clinical correlates after stem cell transplantation for systemic sclerosis
M. Vasconcelos, Maynara Santana-Gonçalves, Djúlio César Zanin-Silva, Kelen Cristina Ribeiro Malmegrim, Maria Carolina Oliveira · 2022 · Frontiers in Immunology
Low immune index correlates with favorable prognosis but with reduced benefit from chemotherapy in gallbladder cancer
Jie Wang, Xiaobo Bo, Changcheng Wang, Yanlei Xin, Lingxi Nan, Rongkui Luo, Lingli Chen, Xiao Shi, Tao Suo, Xiaoling Ni et al. · 2019 · Cancer Science
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis
Sara Turcinov, Ravi Kumar Sharma, Charlotte De Vries, Alexandra Cîrciumaru, Christina Gerstner, Linda Mathsson‐Alm, Bruno Raposo, Anatoly P. Dubnovitsky, Lars Rönnblom, William W. Kwok et al. · 2024 · RMD Open
Predictive biomarkers in the era of immunotherapy for gastric cancer: current achievements and future perspectives
Fujing Sun, Xiaozhuo Gao, Wentao Wang, Xiaoyan Zhao, Jingdong Zhang, Yanmei Zhu · 2025 · Frontiers in Immunology
Differential inhibition of T-cell receptor and STAT5 signaling pathways determines the immunomodulatory effects of dasatinib in chronic phase chronic myeloid leukemia
Patrick Harrington, Richard James Dillon, Deepti H. Radia, Philippe H. Rousselot, Donal P. McLornan, Mark Ong, Anna C. Green, Alessandro Verde, Farzana Hussain, Kavita K Raj et al. · 2023 · Haematologica
In situ analysis of CCR8+ regulatory T cells in lung cancer: suppression of GzmB+ CD8+ T cells and prognostic marker implications
Yoshinori Hayashi, Azumi Ueyama, Soichiro Funaki, Koichi Jinushi, Naoko Higuchi, Hitomi Morihara, Michinari Hirata, Yoji Nagira, Takuro Saito, Atsunari Kawashima et al. · 2024 · BMC Cancer
Targeting Setdb1 in T cells induces transplant tolerance without compromising antitumor immunity
Xiaosheng Tan, Xiangli Zhao, Zunsong Hu, Ding‐Sheng Jiang, Zhibo Ma, Lingjuan Sun, Jingzeng Wang, Xia Huang, Bin Xie, Mi Wu et al. · 2025 · Nature Communications
Tumor-migrating peripheral Foxp3-high regulatory T cells drive poor prognosis in HCC
Chien‐Hao Huang, Wei-Ting Ku, Jayashri Mahalingam, Cheng‐Heng Wu, Tsung‐Han Wu, J P Fan, Chung‐Wei Su, Po‐Ting Lin, Chien‐Wei Peng, Chan‐Keng Yang et al. · 2025 · Hepatology
Characterization of KIR + NKG2A + Eomes− NK‐like CD8+ T cells and their decline with age in healthy individuals
Dimitri Kasakovski, Xiangbo Zeng, Jing Lai, Zhi Hui Yu, Danlin Yao, Shaohua Chen, Xianfeng Zha, Yangqiu Li, Ling Xu · 2020 · Cytometry Part B Clinical Cytometry
Zingerone improves the immune responses in an animal model of breast cancer
Modje Kazemi, Abdollah Jafarzadeh, Maryam Nemati, Fereshteh Taghipour, Omolbanin Oladpour, Mohammad Taghi Rezayati, Hossein Khorramdelazad, Zuhair Mohammad Hassan · 2021 · Journal of Complementary and Integrative Medicine
The role of PD-1/PD-Ls in the pathogenesis of IgG4-related disease
Xia Zhang, Hui Lu, Linyi Peng, Jiaxin Zhou, Mu Wang, Jieqiong Li, Zheng Liu, Wen Zhang, Yan Zhao, Xiaofeng Zeng et al. · 2021 · Rheumatology
The Immunopathobiology of SARS-CoV-2 Infection
Milankumar Patel, Farah Shahjin, Jacob D. Cohen, Mahmudul Hasan, Jatin Machhi, Heerak Chugh, Snigdha Singh, Srijanee Das, Tanmay A. Kulkarni, Jonathan Herskovitz et al. · 2021 · FEMS Microbiology Reviews
Systemic Profiling of KDM5 Subfamily Signature in Non-Small-Cell Lung Cancer
Hao Fang · 2021 · International Journal of General Medicine
Eltrombopag modulates the phenotypic evolution and potential immunomodulatory roles of monocytes/macrophages in immune thrombocytopenia
Feifei Yang, Hui Zong, Feng Li, Shulin Luo, Xiuqun Zhang, Yanli Xu, Xuezhong Zhang · 2022 · Platelets
The Interplay of Transcription and Genome Topology Programs T Cell Development and Differentiation
Xin Zhao, Shaoqi Zhu, Weiqun Peng, Hai‐Hui Xue · 2022 · The Journal of Immunology
A modified flow cytometry method for objective estimation of human CD4+ regulatory T cells (CD4+ Tregs) in peripheral blood, via CD4/CD25/CD45RO/FoxP3 labeling
Asimina Petsiou, Stavroula Α. Paschou, George Vartholomatos, Katerina Chatzigianni, Nikolaos I. Kolaitis, Eleni Giotaki, George P. Bondinas, Antonis K. Moustakas, Achilleas Karamoutsios, Eleftheria K. Zervou et al. · 2019 · Cytometry Part B Clinical Cytometry
Regulatory T cell subsets in bullous pemphigoid and dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid
Ken Muramatsu, Miao Zheng, Norihiro Yoshimoto, Takamasa Ito, Inkin Ujiie, Hiroaki Iwata, Hiroshi Shimizu, Hideyuki Ujiie · 2020 · Journal of Dermatological Science
The effect of CCL5 on the immune cells infiltration and the prognosis of patients with kidney renal clear cell carcinoma
Shuheng Bai, Yinying Wu, Yanli Yan, Haojing Kang, Jiangzhou Zhang, Wen Ma, Ying Gao, Beina Hui, Rong Li, Xiaozhi Zhang et al. · 2020 · International Journal of Medical Sciences
Selective disruption of lipid peroxide homeostasis in intratumoral regulatory T cells by targeting FSP1 enhances cancer immunity
Jesse Garcia Castillo, Stephanie L. Silveria, Leo Schirokauer, Antoine Sauquet, Jessica Hung, Grace Jaworski, Joseph M. Hendricks, Hei Sook Sul, James A. Olzmann, Michel J.P. DuPage · 2026 · Science Advances
Immunocyte density in parathyroid carcinoma is correlated with disease relapse
Ya Hu, Ming Cui, Yalan Bi, Xuan Zhang, M Wang, Surong Hua, Quan Liao, Yupei Zhao · 2020 · Journal of Endocrinological Investigation
Comprehensive Analysis of Prognostic and immune infiltrates for FOXPs Transcription Factors in Human Breast Cancer
Jianing Yi, Siyi Tan, Yuanjun Zeng, Lianhong Zou, Jie Zeng, Chaojie Zhang, Luyao Liu, Peizhi Fan · 2022 · Scientific Reports
Modulation of immunosuppressive cells and noncoding RNAs as immunotherapy in osteosarcoma
Yidan Xia, Dongxu Wang, Yuting Piao, Minqi Chen, Duo Wang, Ziping Jiang, Bin Liu · 2022 · Frontiers in Immunology
CD25 targeting with the afucosylated human IgG1 antibody RG6292 eliminates regulatory T cells and CD25+ blasts in acute myeloid leukemia
Laurène Pousse, Koorosh Korfi, Bruno C. Medeiros, Marco Berrera, Nadine Kumpesa, Jan Eckmann, Idil Hutter-Karakoc, Vera Griesser, Vaios Karanikas, Christian Klein et al. · 2023 · Frontiers in Oncology
Pathogenesis, pathological characteristics and individualized therapy for immune-related adverse effects
Kang Miao, Li Zhang · 2023 · Chinese Medical Journal - Pulmonary and Critical Care Medicine
Translational kinetic‐pharmacodynamics of mRNA‐6231, an investigational mRNA therapeutic encoding mutein interleukin‐2
Ivana Liric Rajlic, Beatriz Guglieri-López, Nabeel Rangoonwala, Vijay D. Ivaturi, Linh M. Van, Simone Mori, Brian T. Wipke, Douglas S. Burdette, Husain Z. Attarwala · 2024 · CPT Pharmacometrics & Systems Pharmacology
SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration
Xiaoqian Liu, Kuai Liu, Yuxi Wang, Xiaoyu Meng, Qianqian Wang, Sijue Tao, Qianying Xu, Xin Shen, Xianzhi Gao, Shenghui Hong et al. · 2024 · Cell Reports
Exercise, autoimmune diseases and T-regulatory cells
Miri Blank, Daphna Israeli, Yehuda Shoenfeld · 2024 · Journal of Autoimmunity
Dynamics of effector and naïve Regulatory T cells throughout pregnancy
Naoya Shigeta, Keiichi Kumasawa, Atsushi Tanaka, James B. Wing, Hitomi Nakamura, Shimon Sakaguchi, Tadashi Kimura · 2020 · Journal of Reproductive Immunology
Identification of Significant Genes and Pathways in Acute Pancreatitis via Bioinformatical Analysis
Ran Ji, Ying Chen, Weiwei Chen, Yuming Wang, Fangchen Gong, Shunwei Huang, Rongli Xie, Ming Zhong, Zhaojun Liu, Zhitao Yang et al. · 2020 · Digestive Diseases and Sciences
Immunity, virus evolution, and effectiveness of SARS-CoV-2 vaccines
José Ernesto Belizário · 2021 · Brazilian Journal of Medical and Biological Research
Prognostic Model Construction and Immune Microenvironment Analysis of Breast Cancer Based on Ferroptosis-Related lncRNAs
Cong Li Jia, Yang Fu, Ruining Li · 2021 · International Journal of General Medicine
Toward a Paradigm to Distinguish Distinct Functions of FOXP3+ Regulatory T Cells
Samuel Edward Weinberg, Benjamin David Singer · 2021 · ImmunoHorizons
TNFR2/CCR8 bispecific antibody enhances antitumor activity through depleting Ti-Tregs and boosting effector CD8 + T cell function
Ran Wang, Jiefang Xu, Shipeng Cheng, Zhiyang Ling, Sonam Wangmo, Jichao Yang, Fuquan Jin, Jing Wen, Xiao Jie Lu, Liyan Ma et al. · 2025 · OncoImmunology
The progress and perspective of nanomedicine in modulating the tumor immune microenvironment
Nan Lin, Keqin Tan, Yuhao Wei, Songtao Xie, Jiaming Liu, Xuelei Ma · 2025 · Acta Pharmaceutica Sinica B
Spatial transcriptomics reveals immune-stromal crosstalk within the synovium of patients with juvenile idiopathic arthritis
Jun Inamo, Roselyn Fierkens, Michael R. Clay, Anna Helena Jonsson, Clara Lin, Kari Hayes, Nathan D. Rogers, Heather Leach, Kentaro Yomogida · 2025 · JCI Insight
Antigen Processing, Presentation, and Tolerance: Role in Autoimmune Skin Diseases
Jörg C. Prinz · 2021 · Journal of Investigative Dermatology
Identification of Treg-related prognostic molecular subtypes and individualized characteristics in clear cell renal cell carcinoma through single-cell transcriptomes and bulk RNA sequencing
Kang qiang Weng, Jin Yu Liu, Li Hu, Lin Lu She, Jun Qiu, Hao Qi, Hui Yue Qi, Yong-Sheng Li, Ying Dai · 2024 · International Immunopharmacology
Preclinical and translational pharmacology of afucosylated anti‐CCR8 antibody for depletion of tumour‐infiltrating regulatory T cells
Gautham Gampa, Phillip C. Spinosa, Jennifer A. Getz, Yu Min Zhong, Wendy Halpern, Emel Esen, John Davies, Cassie K. Chou, Mandy Kwong, Yingyun Wang et al. · 2024 · British Journal of Pharmacology
CKLF instigates a “cold” microenvironment to promote MYCN-mediated tumor aggressiveness
Xiaodan Qin, Andrew Lam, Xu Zhang, Satyaki Sengupta, Julian Bryan Iorgulescu, Hongru Ni, Sanjukta Das, Madison Rager, Zhenwei Zhou, Tao Zuo et al. · 2024 · Science Advances
Transcriptional switches in melanoma T Cells: Facilitating polarizing into regulatory T cells
Tengda Li, Tianqin Wu, Xiang Li, Cheng Qian · 2024 · International Immunopharmacology
Selenium nanoparticles enhance the anti-tumor immune responses of anti-4-1BB antibody and alleviate the adverse effects on mice
L Zhang, Houru Liu, Jie Shen, Wenting Liu, Dahai Liu, Liansheng Cheng, Bei Huang · 2024 · Immunobiology
Precision Spatial Control of Tumor‐Stroma Interactions in Cancer Models via 3D Bioprinting for Advanced Research and Therapy
Yan Li, Haijun Cui, Haitao Cui · 2025 · Advanced Functional Materials
Bone marrow microenvironment in myelodysplastic neoplasms: insights into pathogenesis, biomarkers, and therapeutic targets
Forouzan Bahmani, Maryam Shayanmanesh, Mahdi Safari, Amirarsalan Alaei, Yasaman Pouriafar, Zahra Rasti, Farhad Zaker, Shahrbano Rostami, Fatemeh Damerchiloo, Majid Safa · 2025 · Cancer Cell International
Fungi and cancer: unveiling the complex role of fungal infections in tumor biology and therapeutic resistance
Wanli Zhang, He Zhang, Yiru Gao, Jianjun Lei, Chenhao Suo · 2025 · Frontiers in Cellular and Infection Microbiology
The expression pattern of Immune checkpoints after chemo/radiotherapy in the tumor microenvironment
Hamidreza Hassanian, Zahra Asadzadeh, Amir Baghbanzadeh, Afshin Derakhshani, Antoine Dufour, Nazanin Rostami Khosroshahi, Souzan Najafi, Oronzo Brunetti, Nicola Silvestris, Behzad Baradaran · 2022 · Frontiers in Immunology
Engineered Hybrid Treg-Targeted Nanosomes Restrain Lung Immunosuppression by Inducing Intratumoral CD8+T Cell Immunity
Kalliopi Domvri, Savvas Petanidis, Paul Zarogoulidis, Doxakis Anestakis, Charalampos Charalampidis, Drosos Tsavlis, Haidong Huang, Lutz Freitag, Wolfgang Hohenforst‐Schmidt, Dimitris Matthaios et al. · 2022 · International Journal of Nanomedicine
Effect of neoadjuvant chemotherapy on tumor immune infiltration in breast cancer patients: Systematic review and meta-analysis
Manuela Llano-León, Laura Camila Martínez-Enriquez, Oscar Mauricio Rodríguez Bohórquez, Esteban Alejandro Velandia Vargas, Nicolás Lalinde-Ruiz, Maria Alejandra Villota-Álava, Ivón Johanna Rodríguez, María del Pilar Montilla Velásquez, Carlos Parra-López · 2023 · PLoS ONE
De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness
Jaemoon Koh, Yeon Duk Woo, Hyun Jung Yoo, Jun‐Pyo Choi, Sae‐Hoon Kim, Yoon‐Seok Chang, Kyeong Cheon Jung, Ji Hyung Kim, Yoon Kyung Jeon, Hye Young Kim et al. · 2023 · eLife
Regulatory T cells in lung disease and transplantation
Peizhen Lao, Jingyi Chen, Longqian Tang, Jiwen Zhang, Yuxi Chen, Yuyin Fang, Xingliang Fan · 2023 · Bioscience Reports
M6A-mediated molecular patterns and tumor microenvironment infiltration characterization in nasopharyngeal carcinoma
Yong Wang, Lisha Peng, Feng Wang · 2024 · Cancer Biology & Therapy
mTORC1 Inhibition Protects Human Regulatory T Cells From Granzyme-B-Induced Apoptosis
Siawosh K. Eskandari, Hazim Allos, Basmah S. Al Dulaijan, Gandolina Melhem, Ina Sulkaj, Juliano B. Alhaddad, Anis J. Saad, Christa A. Deban, Philip Chu, John Yongjoon Choi et al. · 2022 · Frontiers in Immunology
The biological behavior and clinical outcome of pituitary adenoma are affected by the microenvironment
Yuhe Li, Xiufang Ren, Wei Gao, Ruikai Cai, Jianqi Wu, Tianqi Liu, Xin Chen, Daoming Jiang, Chong Chen, Quan Cheng et al. · 2024 · CNS Neuroscience & Therapeutics
Deep phenotyping of T regulatory cells in psoriatic arthritis highlights targetable mechanisms of disease
Tegan McTaggart, Jing Xuan Lim, Katie J Smith, Bronagh Heaney, David J. McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan M Coxhead, Abbie Ea Degnan, John Dudley Isaacs et al. · 2024 · Journal of Biological Chemistry
Association between somatic microsatellite instability, hypermutation status, and specific T cell subsets in colorectal cancer tumors
Claire Elizabeth Thomas, Yasutoshi Takashima, Evertine Wesselink, Tomotaka Ugai, Robert S. Steinfelder, Daniel D. Buchanan, Conghui Qu, Li Hsu, Andressa Dias Costa, Steve Gallinger et al. · 2024 · Frontiers in Immunology
Regulatory T Cells in Tumor Microenvironment: Therapeutic Approaches and Clinical Implications
Niti Sureka, Sufian Zaheer · 2025 · Cell Biology International
Immunosuppressive mechanisms and therapeutic targeting of regulatory T cells in ovarian cancer
Jing Li, Haojun Huang, Renxian Xie, Rongying Yang, Haitao Wang, Li Wan · 2025 · Frontiers in Immunology
Induction of immune tolerance in NMOSD and MOGAD
Jorge Daniel Correale, Edgar Carnero Contentti · 2025 · Therapeutic Advances in Neurological Disorders
Decreased numbers and sex-based differences of circulating regulatory T cells in patients with seropositive undifferentiated arthritis
Hong-Qing Niu, Chenrui Yuan, Chenglan Yan, Na Li, Yuansheng Lei, Xuxu Li, Jinli Ru, Xiaofeng Li · 2021 · Therapeutic Advances in Chronic Disease
Interplay between Mast Cells and Regulatory T Cells in Immune-Mediated Cholangiopathies
Natalia Krajewska, Rémi Fiancette, Ye Htun Oo · 2022 · International Journal of Molecular Sciences
The role of immune cells in the liver tumor microenvironment: an involvement of gut microbiota-derived factors
Tomonori Kamiya, Naoko Ohtani · 2022 · International Immunology
Intratumoral Niches of B Cells and Follicular Helper T Cells, and the Absence of Regulatory T Cells, Associate with Longer Survival in Early-Stage Oral Tongue Cancer Patients
Chumut Phanthunane, Rebecca Wijers, Maria J. De Herdt, Senada Koljenović, Stefan Sleijfer, Robert J. Baatenburg de Jong, José A. Hardillo, Reno Debets, Hayri Emrah Balcioglu · 2022 · Cancers
Intratumoral Foxp3+RORγt+ T cell infiltration determines poor prognosis and immunoevasive contexture in gastric cancer patients
Yuchao Fei, Yifan Cao, Yun Gu, Hanji Fang, Yifan Chen, Jieti Wang, Xin Liu, Kunpeng Lv, Xudong He, Chao Lin et al. · 2021 · Cancer Immunology Immunotherapy
The potential application of PD-1 blockade therapy for early-stage biliary tract cancer
Kumiko Umemoto, Yosuke Togashi, Yasuhito Arai, Hiromi K. Nakamura, Shinichiro Takahashi, Tokiyoshi Tanegashima, Mikiya Kato, Tsubasa Nishikawa, Daisuke Sugiyama, Motohiro Kojima et al. · 2019 · International Immunology
Preclinical and Clinical Immunotherapeutic Strategies in Epithelial Ovarian Cancer
Alejandra Martínez, Jean‐Pierre Delord, Maha Ayyoub, Christel Devaud · 2020 · Cancers
Integrative epigenetic analysis reveals AP-1 promotes activation of tumor-infiltrating regulatory T cells in HCC
Baowen Zhuo, Qifan Zhang, Tingyan Xie, Yidan Wang, Zhengliang Chen, Daming Zuo, Bo Guo · 2023 · Cellular and Molecular Life Sciences
Mono-Carbonyl Curcumin Analogs for Cancer Therapy
Takashi Maruyama, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Hiroyuki Shibata · 2023 · Biological and Pharmaceutical Bulletin
The role of dysregulated mRNA translation machinery in cancer pathogenesis and therapeutic value of ribosome-inactivating proteins
Wentao Jia, Jiaying Yuan, Shu Li, Binbin Cheng · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Advances in tumor immune microenvironment of head and neck squamous cell carcinoma: A review of literature
Qichao Hong, Shun Ding, Chengliang Xing, Zhonglin Mu · 2024 · Medicine
Prognostic value of tumor‐infiltrating lymphocytes and PD ‐ L1 expression in esophageal squamous cell carcinoma
Jie Hu, Takeshi Toyozumi, Kentaro Murakami, Satoshi Endo, Yasunori Matsumoto, Ryota Otsuka, Tadashi Shiraishi, Shinichiro Iida, Hiroki Morishita, Tenshi Makiyama et al. · 2024 · Cancer Medicine