Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer

Safety, activity, and immune correlates of anti–PD-1 antibody in cancer

Topalian, S. L., Hodi, F. S., Brahmer, J. R., Gettinger, S. N., Smith, D. C., McDermott, D. F., Powderly, J. D., Carvajal, R. D., Sosman, J. A., Atkins, M. B., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1200690 · Cited by 12,628

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Fontenot, J. D., Gavin, M. A., & Rudensky, A. Y. (2003) · Nature Immunology · doi:10.1038/ni904 · Cited by 7,745

The Immune Landscape of Cancer

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., & Toda, M. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.3.1151 · Cited by 5,608

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Freeman, G. J., Long, A. J., Iwai, Y., Bourque, K., Chernova, T., Nishimura, H., Fitz, L. J., Malenkovich, N., Okazaki, T., Byrne, M. C., et al. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.7.1027 · Cited by 5,294

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

Charoentong, P., Finotello, F., Angelova, M., Mayer, C., Efremova, M., Rieder, D., Hackl, H., & Trajanoski, Z. (2017) · Cell Reports · doi:10.1016/j.celrep.2016.12.019 · Cited by 5,041

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

Dong, H., Strome, S. E., Salomao, D. R., Tamura, H., Hirano, F., Flies, D. B., Roche, P. C., Lu, J., Zhu, G., Tamada, K., et al. (2002) · Nature Medicine · doi:10.1038/nm730 · Cited by 5,025

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M., Ferguson, P., Whitesell, L., Kelly, T., Saulsbury, F., Chance, P., & Ochs, H. (2001) · Nature Genetics · doi:10.1038/83713 · Cited by 3,576

Regulatory T Cells in Autoimmune Hepatitis: Unveiling Their Roles in Mouse Models and Patients

Wang, H., Feng, X., Yan, W., & Tian, D. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.575572 · Cited by 57

Immune cellular components and signaling pathways in the tumor microenvironment

Yenyuwadee, S., Aliazis, K., Wang, Q., Christofides, A., Shah, R., Patsoukis, N., & Boussiotis, V. A. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.08.004 · Cited by 54

Identification and classification of distinct surface markers of T regulatory cells

Węgrzyn, A., Kedzierska, A. E., & Obojski, A. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1055805 · Cited by 56

Role of Treg cell subsets in cardiovascular disease pathogenesis and potential therapeutic targets

Xia, Y., Gao, D., Wang, X., Liu, B., Shan, X., Sun, Y., & Ma, D. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1331609 · Cited by 58

Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2–expressing Treg cells

Ronin, É., Pouchy, C., Khosravi, M., Hilaire, M., Grégoire, S., Casrouge, A., Kassem, S., Sleurs, D., Martin, G. H., Chanson, N., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2014043118 · Cited by 62

Activated CTLA‐4‐independent immunosuppression of Treg cells disturbs CTLA‐4 blockade‐mediated antitumor immunity

Watanabe, T., Ishino, T., Ueda, Y., Nagasaki, J., Sadahira, T., Dansako, H., Araki, M., & Togashi, Y. (2023) · Cancer Science · doi:10.1111/cas.15756 · Cited by 53

Interactions between LAMP3+ dendritic cells and T-cell subpopulations promote immune evasion in papillary thyroid carcinoma

Wang, Z., Ji, X., Zhang, Y., Yang, F., Su, H., Zhang, H., Li, Z., Zhang, W., & Sun, W. (2024) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2024-008983 · Cited by 54

Role of Epigenetics in the Regulation of Immune Functions of the Skin

Sawada, Y., & Gallo, R. L. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.10.012 · Cited by 53

PD-1+ Treg cells: a foe in cancer immunotherapy?

Aksoylar, H., & Boussiotis, V. A. (2020) · Nature Immunology · doi:10.1038/s41590-020-0801-7 · Cited by 53

Sympathetic nervous tone limits the development of myeloid-derived suppressor cells

Nevin, J. T., Moussa, M. R., Corwin, W. L., Măndoiu, I., & Srivastava, P. K. (2020) · Science Immunology · doi:10.1126/sciimmunol.aay9368 · Cited by 48

Bystander CD4 + T cells infiltrate human tumors and are phenotypically distinct

Li, S., Zhuang, S., Heit, A., Koo, S., Tan, A. C., Chow, I., Kwok, W. W., Tan, I. B., Tan, D. S. W., Simoni, Y., et al. (2022) · OncoImmunology · doi:10.1080/2162402x.2021.2012961 · Cited by 48

Reactive oxygen species formation and its effect on CD4+ T cell-mediated inflammation

Shu, P., Liang, H., Zhang, J., Lin, Y., Chen, W., & Zhang, D. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1199233 · Cited by 58

Treg cell: Critical role of regulatory T-cells in depression

Gao, X. W., Tang, Y., Kong, L., Fan, Y., Wang, C., & Wang, R. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106893 · Cited by 51

Revisiting PD-1/PD-L pathway in T and B cell response: Beyond immunosuppression

Lu, J., Wu, J., Mao, L., Xu, H., & Wang, S. (2022) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2022.07.003 · Cited by 51

The protective and pathogenic role of Th17 cell plasticity and function in the tumor microenvironment

Pan, Y., Yang, W., Tang, B., Wang, X., Zhang, Q., Li, W., & Li, L. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1192303 · Cited by 53

Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood

Motwani, K., Peters, L. D., Vliegen, W. H., Elsayed, A. G., Seay, H. R., López, M. C., Baker, H. V., Posgai, A. L., Brusko, M., Perry, D. J., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00611 · Cited by 50

Tertiary lymphoid structures in cancer: spatiotemporal heterogeneity, immune orchestration, and translational opportunities

Deng, S., Chen, Y., Song, B., Wang, H., Huang, S., Wu, K., & Chu, Q. (2025) · Journal of Hematology & Oncology · doi:10.1186/s13045-025-01754-7 · Cited by 54

Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma

Wei, J., Yao, J., Yang, C., Mao, Y., Zhu, D., Xie, Y., Liu, P., Yan, M., Ren, L., Lin, Y., et al. (2022) · Journal of Translational Medicine · doi:10.1186/s12967-022-03778-w · Cited by 48

FoxP3 in Treg cell biology: a molecular and structural perspective

Deng, G., Song, X., & Greene, M. I. (2019) · Clinical & Experimental Immunology · doi:10.1111/cei.13357 · Cited by 50

A theoretical framework of immune cell phenotypic classification and discovery

Hu, Y., Liu, C., Han, W., & Wang, P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1128423 · Cited by 46

Regulatory T cells in autoimmune kidney diseases and transplantation

Mikami, N., & Sakaguchi, S. (2023) · Nature Reviews Nephrology · doi:10.1038/s41581-023-00733-w · Cited by 46

Gut microbiota determines the fate of dietary fiber-targeted interventions in host health

Wang, W., Fan, Z., Yan, Q., Pan, T., Luo, J., Wei, Y., Li, B., Fang, Z., & Lu, W. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2416915 · Cited by 47

Developmental bifurcation of human T follicular regulatory cells

Kumar, S., Fonseca, V. R., Ribeiro, F., Basto, A. P., Agua‐Doce, A., Monteiro, M., Elessa, D., Miragaia, R. J., Gomes, T., Piaggio, E., et al. (2021) · Science Immunology · doi:10.1126/sciimmunol.abd8411 · Cited by 47

The Coevolution of Placentation and Cancer

Wagner, G. P., Gupta, K., Dighe, A., & Levchenko, A. (2021) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-020420-031544 · Cited by 45

T cell optimization for graft-versus-leukemia responses

Biernacki, M. A., Sheth, V., & Bleakley, M. (2020) · JCI Insight · doi:10.1172/jci.insight.134939 · Cited by 45

Phenotypic and Functional Diversity in Regulatory T Cells

Sjaastad, L. E., Owen, D. L., Tracy, S. I., & Farrar, M. A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.715901 · Cited by 50

Reframing How Physical Activity Reduces The Incidence of Clinically-Diagnosed Cancers: Appraising Exercise-Induced Immuno-Modulation As An Integral Mechanism

Emery, A., Moore, S. E., Turner, J. E., & Campbell, J. P. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.788113 · Cited by 49

NETosis : Sculpting tumor metastasis and immunotherapy

Hu, Y., Wang, H., & Liu, Y. (2023) · Immunological Reviews · doi:10.1111/imr.13277 · Cited by 43

Synovial Tissue Inflammation Mediated by Autoimmune T Cells

Takeuchi, Y., Hirota, K., & Sakaguchi, S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01989 · Cited by 44

Role of Immune Cells in Patients with Hepatitis B Virus-Related Hepatocellular Carcinoma

Cho, H. J., & Cheong, J. Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158011 · Cited by 51

Sustained Antitumor Immunity Based on Persistent Luminescence Nanoparticles for Cancer Immunotherapy

Wang, R., Shi, J., Song, L., Zheng, S., Liu, X., Hong, M., & Zhang, Y. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202106884 · Cited by 44

Mesenchymal Stem Cell Immunomodulation: A Novel Intervention Mechanism in Cardiovascular Disease

Wang, Y., Qi, Z., Yan, Z., Ji, N., Yang, X., Gao, D., Hu, L., Lv, H., Zhang, J., & Li, M. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.742088 · Cited by 46

4-1BBL–containing leukemic extracellular vesicles promote immunosuppressive effector regulatory T cells

Swatler, J., Turos-Korgul, L., Brewińska‐Olchowik, M., Biasi, S. D., Dudka, W., Le, B. V., Kominek, A., Cyranowski, S., Pilanc, P., Mohammadi, E., et al. (2022) · Blood Advances · doi:10.1182/bloodadvances.2021006195 · Cited by 43

Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells and PD-1 Expression

Ferreira, R. C., Dopico, X. C., de Oliveira, J. J., Rainbow, D. B., Yang, J. H. M., Trzupek, D., Todd, S. A., McNeill, M., Steri, M., Orrù, V., et al. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02606 · Cited by 43

Reprogramming Immune Cells for Enhanced Cancer Immunotherapy: Targets and Strategies

Dong, Y., Wan, Z., Gao, X., Yang, G., & Liu, L. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.609762 · Cited by 44

Unraveling the Heterogeneity and Ontogeny of Dendritic Cells Using Single-Cell RNA Sequencing

Chen, B., Zhu, L., Yang, S., & Su, W. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.711329 · Cited by 43

Regulatory T cells in gastric cancer: Key controllers from pathogenesis to therapy

Negură, I., Tanasa, M. P., & Danciu, M. (2023) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2023.102629 · Cited by 44

Neuropilin‐1 is present on Foxp3+ T regulatory cell‐derived small extracellular vesicles and mediates immunity against skin transplantation

Campos‐Mora, M., Solminihac, J. D., Rojas, C., Padilla, C. R., Kurte, M., Pacheco, R., Kaehne, T., Wyneken, Ú., & Pino‐Lagos, K. (2022) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12237 · Cited by 42

TGF-β Enhances Immunosuppression of Myeloid-Derived Suppressor Cells to Induce Transplant Immune Tolerance Through Affecting Arg-1 Expression

Cao, P., Sun, Z., Zhang, F., Zhang, J., Xiang, Z., Yu, B., Zhao, Y. X., Wang, W., & Wang, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.919674 · Cited by 41

The relationship between TIGIT+ regulatory T cells and autoimmune disease

Lee, D. J. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106378 · Cited by 43

Role of T cells in the pathogenesis and treatment of gout

Wang, B., Chen, S., Qian, H., Zheng, Q., Chen, R., Liu, Y., & Shi, G. (2020) · International Immunopharmacology · doi:10.1016/j.intimp.2020.106877 · Cited by 41

Systematic review of the immunological landscape of Wilms tumors

Palmisani, F., Kovar, H., Kager, L., Amann, G., Metzelder, M. L., & Bergmann, M. M. (2021) · Molecular Therapy — Oncolytics · doi:10.1016/j.omto.2021.06.016 · Cited by 40

Regulatory T Cell Therapy of Graft-versus-Host Disease: Advances and Challenges

Hefazi, M., Bolivar-Wagers, S., & Blazar, B. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189676 · Cited by 40

Overcoming cancer risk in inflammatory bowel disease: new insights into preventive strategies and pathogenesis mechanisms including interactions of immune cells, cancer signaling pathways, and gut microbiota

Zhang, H., Shi, Y., Lin, C., He, C., Wang, S., Li, Q., Sun, Y. P., & Li, M. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1338918 · Cited by 40

Residual cancer burden index and tumor-infiltrating lymphocyte subtypes in triple-negative breast cancer after neoadjuvant chemotherapy

Pinard, C., Debled, M., Rejeb, H. B., Velasco, V., de Lara, C. T., Hoppe, S., Richard, É., Brouste, V., Bonnefoi, H. R., & MacGrogan, G. M. (2019) · Breast Cancer Research and Treatment · doi:10.1007/s10549-019-05437-z · Cited by 40

Poor clinical outcomes of intratumoral dendritic cell–specific intercellular adhesion molecule 3–grabbing non-integrin–positive macrophages associated with immune evasion in gastric cancer

Liu, X., Cao, Y., Li, R., Gu, Y., Chen, Y., Qi, Y., Lv, K., Wang, J., Yu, K., Lin, C., et al. (2020) · European Journal of Cancer · doi:10.1016/j.ejca.2020.01.002 · Cited by 39

Multiple Sclerosis: Lipids, Lymphocytes, and Vitamin D

Hayes, C. E., & Ntambi, J. M. (2020) · Immunometabolism · doi:10.20900/immunometab20200019 · Cited by 41

Bacteroides thetaiotaomicron Ameliorates Experimental Allergic Airway Inflammation via Activation of ICOS+Tregs and Inhibition of Th2 Response

Pang, W., Jiang, Y., Li, A., Zhang, J., Chen, M., Li, H., Li, Z., & Wang, D. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.620943 · Cited by 39

Tolerogenic Nanovaccine for Prevention and Treatment of Autoimmune Encephalomyelitis

Park, J.-W., Le, Q., Wu, Y., Lee, J., & Oh, Y. (2022) · Advanced Materials · doi:10.1002/adma.202202670 · Cited by 39

Asymptomatic and Mild SARS-CoV-2 Infections Elicit Lower Immune Activation and Higher Specific Neutralizing Antibodies in Children Than in Adults

Petrara, M. R., Bonfante, F., Costenaro, P., Cantarutti, A., Carmona, F., Ruffoni, E., Chiara, C. D., Zanchetta, M., Barzon, L., Donà, D., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.741796 · Cited by 41

Chemokine Receptor-Targeted Therapies: Special Case for CCR8

Moser, B. (2022) · Cancers · doi:10.3390/cancers14030511 · Cited by 41

Regulatory T Cells: Angels or Demons in the Pathophysiology of Sepsis?

Gao, Y., Yao, Y., Zhang, X., Chen, F., Meng, X.-L., Chen, X., Wang, C.-L., Liu, Y., Tian, X., Shou, S., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.829210 · Cited by 40

The clinical and immunological characteristics in fatal severe fever with thrombocytopenia syndrome virus (SFTSV) infection

Huang, M., Wang, T., Huang, Y., Wang, Y., Wu, S., Wang, F. Y., Tang, G., Wei, W., Liu, W., & Hou, H. (2023) · Clinical Immunology · doi:10.1016/j.clim.2023.109262 · Cited by 38

Dissecting the roles and clinical potential of YY1 in the tumor microenvironment

Li, M., Wei, J., Xue, C., Zhou, X., Chen, S., Zheng, L., Duan, Y., Deng, H., Xiong, W., Tang, F., et al. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1122110 · Cited by 39

Restoration of Foxp3+ Regulatory T Cells by HDAC-Dependent Epigenetic Modulation Plays a Pivotal Role in Resolving Pulmonary Arterial Hypertension Pathology

Chen, C.-N., Hajji, N., Yeh, F., Rahman, S., Ali, S., Wharton, J., Baxan, N., Zhao, L., Xie, C.-Y., Chen, Y.-G., et al. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202301-0181oc · Cited by 38

Single-cell transcriptomics reveals variations in monocytes and Tregs between gout flare and remission

Yu, H., Xue, W., Yu, H., Song, Y., Liu, X., Qin, L., Wang, S., Bao, H. F., Gu, H., Chen, G., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.171417 · Cited by 38

New insights into the pathogenesis of leprosy: contribution of subversion of host cell metabolism to bacterial persistence, disease progression, and transmission

de Macedo, C. S., Lara, F. A., Pinheiro, R. O., Schmitz, V., Berrêdo‐Pinho, M., Pereira, G. M. B., & Pessolani, M. C. V. (2020) · F1000Research · doi:10.12688/f1000research.21383.1 · Cited by 38

Beneficial and Detrimental Effects of Regulatory T Cells in Neurotropic Virus Infections

Ciurkiewicz, M., Herder, V., & Beineke, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21051705 · Cited by 38

Immunosuppressive Cell Subsets and Factors in Myeloid Leukemias

Swatler, J., Turos-Korgul, L., Kozłowska, E., & Piwocka, K. (2021) · Cancers · doi:10.3390/cancers13061203 · Cited by 38

Targeting neuropilin-1 abolishes anti-PD-1-upregulated regulatory T cells and synergizes with 4-1BB agonist for liver cancer treatment

Wu, Q., Pan, C., Zhou, Y., Wang, S., Xie, L., Zhou, W., Ding, L., Chen, T., Qian, J., Su, R., et al. (2023) · Hepatology · doi:10.1097/hep.0000000000000320 · Cited by 37

Targeting T Cell Activation in Immuno-Oncology

Saibil, S. D., & Ohashi, P. S. (2020) · Current Oncology · doi:10.3747/co.27.5285 · Cited by 39

Evoking pyroptosis with nanomaterials for cancer immunotherapy: Current boom and novel outlook

Sun, Z., & Wang, W.-D. (2022) · Nano TransMed · doi:10.26599/ntm.2022.9130001 · Cited by 36

PD-1 Expression on Intratumoral Regulatory T Cells Is Associated with Lack of Benefit from Anti–PD-1 Therapy in Metastatic Clear-Cell Renal Cell Carcinoma Patients

Denize, T., Jegede, O. A., Matar, S., Ahmar, N. E., West, D. J., Walton, E., Bagheri, A. S., Savla, V., Laimon, Y. N., Gupta, S., et al. (2023) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-23-2274 · Cited by 36

The role of regulatory T-cells in the development of endometriosis

Knez, J., Kovačič, B., & Goropevšek, A. (2024) · Human Reproduction · doi:10.1093/humrep/deae103 · Cited by 36

Role of Regulatory T Cells in Disturbed Immune Homeostasis in Patients With Chronic Obstructive Pulmonary Disease

Hou, J., & Sun, Y. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00723 · Cited by 38

Investigation of the prognostic value of CD4 T cell subsets expanded from tumor-infiltrating lymphocytes of colorectal cancer liver metastases

Kroemer, M., Turco, C., Spehner, L., Viot, J., Idirène, I., Bouard, A., Renaude, E., Deschamps, M., Godet, Y., Adotévi, O., et al. (2020) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2020-001478 · Cited by 37

Immunostimulatory Properties of Chemotherapy in Breast Cancer: From Immunogenic Modulation Mechanisms to Clinical Practice

Zhang, J., Pan, S., Chen, J., Li, H., Dong, J., Sun, Q., Jin, H., & Han, X. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.819405 · Cited by 39

MAGE‐C3 promotes cancer metastasis by inducing epithelial‐mesenchymal transition and immunosuppression in esophageal squamous cell carcinoma

Wu, Q., Zhang, W., Wang, Y., Min, Q., Zhang, H., Dong, D., & Zhan, Q. (2021) · 癌症：英文版 · doi:10.1002/cac2.12203 · Cited by 35

The role of the symbiotic microecosystem in cancer: gut microbiota, metabolome, and host immunome

Xue, X., Li, R., Chen, Z., Li, G., Liu, B., Guo, S., Yue, Q., Yang, S., Xie, L., Zhang, Y., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1235827 · Cited by 37

RAS signaling and immune cells: a sinister crosstalk in the tumor microenvironment

Liu, Y., Xie, B., & Chen, Q. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04486-9 · Cited by 36

Immune modulation in transplant medicine: a comprehensive review of cell therapy applications and future directions

Knoedler, L., Dean, J., Diatta, F. H., Thompson, N. T., Knoedler, S. A., Rhys, R., Sherwani, K., Ettl, T., Mayer, S. A., Falkner, F., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1372862 · Cited by 35

The Versatility of Sirtuin-1 in Endocrinology and Immunology

Rasha, F. A., Mims, B. M., Castro‐Piedras, I., Barnes, B. J., Grisham, M. B., Rahman, R. L., & Pruitt, K. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.589016 · Cited by 35

AKT1/FOXP3 axis-mediated expression of CerS6 promotes p53 mutant pancreatic tumorigenesis

Qi, D., Song, X., Xue, C., Yao, W., Shen, P., Yu, H. T., & Zhang, Z. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.06.024 · Cited by 35

A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer

Jiang, M., Liu, J., Yang, D., Tross, D., Li, P., Chen, F., Alam, M. M., Faustman, D. L., Oppenheim, J. J., & Chen, X. (2021) · International Immunopharmacology · doi:10.1016/j.intimp.2021.108345 · Cited by 35

Th1-Like Treg Cells Are Increased But Deficient in Function in Rheumatoid Arthritis

Zhang, R., Miao, J., Zhang, K., Zhang, B., Luo, X., Sun, H., Zheng, Z., & Zhu, P. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.863753 · Cited by 35

FOXO1 regulates Th17 cell-mediated hepatocellular carcinoma recurrence after hepatic ischemia-reperfusion injury

Ren, H., Chen, Y., Zhu, Z., Xia, J., Liu, S., Hu, Y., Qin, X., Zhang, L., Ding, Y., Xia, S., et al. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-05879-w · Cited by 34

Aconiti Lateralis Radix Praeparata as Potential Anticancer Herb: Bioactive Compounds and Molecular Mechanisms

Zhang, W., Lu, C., Cai, S., Feng, Y., Shan, J., & Di, L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.870282 · Cited by 34

Targeting regulatory T cells in gastric cancer: Pathogenesis, immunotherapy, and prognosis

Wang, B., Zhang, Z., Liu, W., & Tan, B. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114180 · Cited by 38

Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells

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