Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer

Safety, activity, and immune correlates of anti–PD-1 antibody in cancer

Topalian, S. L., Hodi, F. S., Brahmer, J. R., Gettinger, S. N., Smith, D. C., McDermott, D. F., Powderly, J. D., Carvajal, R. D., Sosman, J. A., Atkins, M. B., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1200690 · Cited by 12,628

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Fontenot, J. D., Gavin, M. A., & Rudensky, A. Y. (2003) · Nature Immunology · doi:10.1038/ni904 · Cited by 7,745

The Immune Landscape of Cancer

Thorsson, V., Gibbs, D. L., Brown, S. D., Wolf, D., Bortone, D. S., Ou Yang, T.-H., Porta-Pardo, E., Gao, G. F., Plaisier, C. L., Eddy, J. A., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.03.023 · Cited by 5,870

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Park, J., Adoro, S., Guinter, T. I., Erman, B., Alag, A., Catálfamo, M., Kimura, M. Y., Cui, Y., Lucas, P. J., Gress, R. E., et al. (2010) · Nature Immunology · doi:10.1038/ni.1840 · Cited by 5,835

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., & Toda, M. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.3.1151 · Cited by 5,608

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Freeman, G. J., Long, A. J., Iwai, Y., Bourque, K., Chernova, T., Nishimura, H., Fitz, L. J., Malenkovich, N., Okazaki, T., Byrne, M. C., et al. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.7.1027 · Cited by 5,294

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade

Charoentong, P., Finotello, F., Angelova, M., Mayer, C., Efremova, M., Rieder, D., Hackl, H., & Trajanoski, Z. (2017) · Cell Reports · doi:10.1016/j.celrep.2016.12.019 · Cited by 5,041

Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion

Dong, H., Strome, S. E., Salomao, D. R., Tamura, H., Hirano, F., Flies, D. B., Roche, P. C., Lu, J., Zhu, G., Tamada, K., et al. (2002) · Nature Medicine · doi:10.1038/nm730 · Cited by 5,025

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M., Ferguson, P., Whitesell, L., Kelly, T., Saulsbury, F., Chance, P., & Ochs, H. (2001) · Nature Genetics · doi:10.1038/83713 · Cited by 3,576

Integrated single-cell and spatial transcriptomic profiling reveals that CD177+ Tregs enhance immunosuppression through apoptosis and resistance to immunotherapy in hepatocellular carcinoma

Liang, Y., Qiao, L., Qian, Q., Zhang, R., Yu, H., Xu, X., Xu, Z., Bu, Q., Wang, H., Li, X., et al. (2025) · Oncogene · doi:10.1038/s41388-025-03330-2 · Cited by 10

Reference ranges of T lymphocyte subsets by single-platform among healthy population in southwest China

Wei, B. K., Guo, Y. J., Zhang, L., Zhong, H., Miao, Q., Yan, L., Bai, Y., Feng, W., Liu, W., Niu, Q., et al. (2021) · BMC Immunology · doi:10.1186/s12865-021-00474-0 · Cited by 10

CD137 Agonists Targeting CD137-Mediated Negative Regulation Show Enhanced Antitumor Efficacy in Lung Cancer

Yi, L., Jin, X., Wang, J., Yan, Z., Xu, C., Tao, W., Bin, Y., Wang, X., Che, N., Liu, Z., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.771809 · Cited by 10

Effects of SOCS1-overexpressing dendritic cells on Th17- and Treg-related cytokines in COPD mice

Liao, S., Chen, J., Zhang, L., Zhang, J., Sun, P., & Ouyang, Y. (2022) · BMC Pulmonary Medicine · doi:10.1186/s12890-022-01931-1 · Cited by 10

Determining role of thymus in immune pathogenesis of autoimmune, oncological and infectious diseases

Va, K. (2023) · Medical Immunology (Russia) · doi:10.15789/1563-0625-dro-2591 · Cited by 11

Lithium carbonate accelerates the healing of apical periodontitis

Kagioka, T., Itoh, S., Hue, M. T., Abe, M., & Hayashi, M. (2023) · Scientific Reports · doi:10.1038/s41598-023-34700-z · Cited by 10

High-dimensional analysis of T-cell profiling variations following belimumab treatment in systemic lupus erythematosus

Maeda, S., Hashimoto, H., Maeda, T., Tamechika, S., Isogai, S., Naniwa, T., & Niimi, A. (2023) · Lupus Science & Medicine · doi:10.1136/lupus-2023-000976 · Cited by 10

T cell biology in neuromuscular disorders: a focus on Duchenne Muscular Dystrophy and Amyotrophic Lateral Sclerosis

Lemos, J. P., Tenório, L. P. G., Mouly, V., Butler-Browne, G. S., Mendes‐da‐Cruz, D. A., Savino, W., & Smeriglio, P. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1202834 · Cited by 10

Esophageal cancer cell-derived small extracellular vesicles decrease circulating Tfh/Tfr via sEV-PDL1 to promote immunosuppression

Li, Z., Zhang, Y., He, H., Chen, L., Lv, T., Zhang, X., Qi, Y., & Wang, Z. (2023) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-023-03561-w · Cited by 10

Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion

Hippen, K. L., Furlan, S. N., Roychoudhuri, R., Wang, E., Zhang, Y., Osborn, M. J., Merkel, S. C., Hani, S., MacMillan, M. L., Cichocki, F. M., et al. (2021) · Cytotherapy · doi:10.1016/j.jcyt.2021.02.118 · Cited by 11

Downregulation of TIGIT Expression in FOXP3+Regulatory T Cells in Acute Coronary Syndrome

Xiong, X., Luo, Z., Zhou, H., Duan, Z., Niu, L., Zhang, K., Huang, G., & Li, W. (2022) · Journal of Inflammation Research · doi:10.2147/jir.s351364 · Cited by 10

High-level of intratumoral GITR+ CD4 T cells associate with poor prognosis in gastric cancer

Ke, S., Xie, F., Guo, Y., Chen, J., Wang, Z., Yu, Y., Geng, H., Xu, D., Liu, X., Xia, X., et al. (2022) · iScience · doi:10.1016/j.isci.2022.105529 · Cited by 10

Interleukin‐23 receptor defines T helper 1‐like regulatory T cells in oral squamous cell carcinoma

Li, W., An, N., Wang, M., Liu, X., & Mei, Z. (2022) · Immunity Inflammation and Disease · doi:10.1002/iid3.746 · Cited by 10

The prognostic value of tumour-infiltrating lymphocytes, programmed cell death protein-1 and programmed cell death ligand-1 in Stage I–III triple-negative breast cancer

Sun, G.-Y., Zhang, J., Wang, B., Jing, H., Fang, H., Tang, Y., Song, Y.-W., Jin, J., Liu, Y., Tang, Y., et al. (2023) · British Journal of Cancer · doi:10.1038/s41416-023-02218-w · Cited by 12

Cellular crosstalk of regulatory T cells in pancreatic ductal adenocarcinoma

Shi, X., Liu, H., & Liang, Z. (2023) · Journal of Pancreatology · doi:10.1097/jp9.0000000000000135 · Cited by 10

Gout Management Using Nanocarrier Systems: A Review

Qi, C. W., Nordin, U. U. M., Mahmood, S., Karusan, N. R., Khalid, R., Nordin, N., Fornaguera, C., & Ahmad, N. (2024) · ACS Applied Nano Materials · doi:10.1021/acsanm.3c06079 · Cited by 10

Regulatory T cells in renal cell carcinoma: tumor-promoting mechanisms and emerging therapeutic strategies

Li, Z., Ma, J., Xu, M., Duan, Y., Huang, C., Dai, Q., & Yang, Z. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115322 · Cited by 9

Mitochondrial and lysosomal signaling orchestrates heterogeneous metabolic states of regulatory T cells

Saravia, J., Chapman, N. M., Sun, Y., Meng, X., Risch, I., Li, W., Guy, C. S., Shi, H., Hu, H., Dhungana, Y., et al. (2025) · Science Immunology · doi:10.1126/sciimmunol.ads9456 · Cited by 11

A novel immunogenomic prognostic signature in lung squamous carcinoma

Hou, J., & Zhong, Q. (2021) · Medicine · doi:10.1097/md.0000000000024073 · Cited by 9

Differential effects of Huaier aqueous extract on human CD4+T lymphocytes from patients with primary immune thrombocytopenia

Yuan, B., Yin, C., Ye, X., Bai, Z., Lu, Z., Li, X., Al‐Azab, M., Mu, L., & Li, W. (2021) · Experimental Hematology · doi:10.1016/j.exphem.2021.08.005 · Cited by 9

MUC1 promotes lung metastases of liver cancer by impairing anti-tumor immunity

Yin, Y., Yang, C., Xu, J., Luo, Y., Xia, Q., & He, K. (2023) · Discover Oncology · doi:10.1007/s12672-023-00627-0 · Cited by 9

High post‐chemotherapy TIL and increased CD4+TIL are independent prognostic factors of surgically resected NSCLC following neoadjuvant chemotherapy

Jia, W., Guo, H., Wang, M., Li, J., Yu, J., Zhu, H., & Wu, G. (2023) · MedComm · doi:10.1002/mco2.213 · Cited by 9

Autoimmune Limbic Encephalitis in Patients with Hematologic Malignancies after Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide

Heo, B. Y., Lee, M.-W., Choi, S., Jung, Y., Pham, T. T. D., Jang, Y., Park, J., Kang, S., Koh, J. S., Jo, D., et al. (2023) · Cells · doi:10.3390/cells12162049 · Cited by 9

Knockdown of miR-146a in regulatory T cells suppresses heart transplantation rejection in mice by increasing autophagy

Lu, J. G., Liu, Y., Wang, W., Li, P., & Qi, F. (2021) · Transplant Immunology · doi:10.1016/j.trim.2021.101372 · Cited by 9

Comparative Transcriptomic Analysis Reveals the Immunosuppressive Targets of Mesalazine in Dextran Sulfate Sodium-Induced Ulcerative Colitis

Li, R., Cheng, L., Wang, Q., & Zhou, L. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.698983 · Cited by 9

The frequency of Treg subsets distinguishes disease activity in ANCA vasculitis

Agosto‐Burgos, C., Wu, E. Y., Iannone, M. A., Hu, Y., Hogan, S. L., Henderson, C. D., Kennedy, K. B., Blazek, L. N., Herrera, C. A., Munson, D., et al. (2022) · Clinical & Translational Immunology · doi:10.1002/cti2.1428 · Cited by 9

“To be or not to Be”: Regulatory T cells in melanoma

Ibrahim, Y. S., Amin, A. H., Jawhar, Z. H., ALGhamdi, M. A., Al‐Awsi, G. R. L., Shbeer, A. M., AL-Ghamdi, H. S., Gabr, G. A., Ramírez‐Coronel, A. A., & Almulla, A. F. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110093 · Cited by 10

Graft-Specific Regulatory T Cells for Long-Lasting, Local Tolerance Induction

Seltrecht, N., Hardtke‐Wolenski, M., Iordanidis, K., Jonigk, D. D., Galla, M., Schambach, A., Buitrago‐Molina, L. E., Wedemeyer, H. H., Noyan, F., & Jaeckel, E. (2024) · Cells · doi:10.3390/cells13141216 · Cited by 8

Plac1 + Tumor Cell‐Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer

Meng, X., Liu, Z., Zhao, L., Li, R., Gan, L., Cao, L., Sun, J., Zhang, L., & He, Y. (2025) · Advanced Science · doi:10.1002/advs.202417312 · Cited by 9

Engineering biomaterials for next-generation cancer immunotherapy: From cell manufacturing to in vivo modulation

Liu, Z., Li, Y.-R., Yang, Y., Shen, X., Zhu, E., Nan, H., Wang, S., Lin, J., Yang, L., & Li, S. (2026) · Cell Biomaterials · doi:10.1016/j.celbio.2026.100380 · Cited by 8

TNF–TNFR2 Signal Plays a Decisive Role in the Activation of CD4+Foxp3+ Regulatory T Cells: Implications in the Treatment of Autoimmune Diseases and Cancer

Islam, M. S., Yang, Y., & Chen, X. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-6407-9_13 · Cited by 8

A phase I, first-in-human study to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of MRG-001 in healthy subjects

Ahmadi, A. R., Atiee, G. J., Chapman, B., Reynolds, L., Sun, J. S., Cameron, A. M., Wesson, R., Burdick, J. F., & Sun, Z. (2023) · Cell Reports Medicine · doi:10.1016/j.xcrm.2023.101169 · Cited by 8

CRIF1 deficiency induces FOXP3 LOW inflammatory non-suppressive regulatory T cells, thereby promoting antitumor immunity

Lee, S., Song, S. G., Kim, G., Kim, S., Yoo, H. J., Koh, J., Kim, Y.-J., Tian, J., Cho, E., Choi, Y. S., et al. (2024) · Science Advances · doi:10.1126/sciadv.adj9600 · Cited by 8

Immunoregulatory Effects of the Active Form of Vitamin D (Calcitriol), Individually and in Combination with Curcumin, on Peripheral Blood Mononuclear Cells (PBMCs) of Multiple Sclerosis (MS) Patients

Fasihi, M., Samimi-Badabi, M., Robat-Jazi, B., Bitarafan, S., Moghadasi, A. N., Mansouri, F., Yekaninejad, M. S., Izad, M. H., & Saboor-Yaraghi, A. A. (2024) · Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry · doi:10.2174/0118715230293847240314073359 · Cited by 8

CD8+ T cells infiltrating into tumors were controlled by immune status of pulmonary lymph nodes and correlated with non-small cell lung cancer (NSCLC) patients’ prognosis treated with chemoimmunotherapy

Bai, Z., Cheng, X., Ma, T., Li, G., Wang, X., Wang, Z., Yi, L., & Liu, Z. (2024) · Lung Cancer · doi:10.1016/j.lungcan.2024.107991 · Cited by 9

Analysis of effector/memory regulatory T cells from arrhythmogenic cardiomyopathy patients identified IL-32 as a novel player in ACM pathogenesis

Soussi, S., Maione, A. S., Lefèvre, L., Pizzinat, N., Iacovoni, J. S., Gonzalez-Fuentes, I., Cussac, D., Iengo, L., Santin, Y., Tundo, F., et al. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07364-y · Cited by 10

Alteration of the immune environment in bone marrow from children with recurrent B cell precursor acute lymphoblastic leukemia

Mikami, T., Kato, I., Wing, J. B., Ueno, H., Tasaka, K., Tanaka, K., Kubota, H., Saida, S., Umeda, K., Hiramatsu, H., et al. (2021) · Cancer Science · doi:10.1111/cas.15186 · Cited by 8

Are there differences in immune responses following delivery of vaccines through acutely or chronically sun‐exposed compared with sun‐unexposed skin?

Hart, P. H., & Norval, M. (2019) · Immunology · doi:10.1111/imm.13128 · Cited by 8

A Novel Liposome Formulation Carrying Both an Insulin Peptide and a Ligand for Invariant Natural Killer T Cells Induces Accumulation of Regulatory T Cells to Islets in Nonobese Diabetic Mice

Akimoto, H., Fukuda-Kawaguchi, E., Duramad, O., Ishii, Y., & Tanabe, K. (2019) · Journal of Diabetes Research · doi:10.1155/2019/9430473 · Cited by 8

Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potential

Kattelus, R., Starskaia, I., Lindén, M., Batkulwar, K., Pietilä, S., Moulder, R., Marson, A., Rasool, O., Suomi, T., Elo, L. L., et al. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05429-3 · Cited by 7

Elevated IL-17A-Secreting Regulatory T Cells in Sinonasal Tissues of Chronic Rhinosinusitis with Nasal Polyps

Ryu, G., Bae, J.-S., Yoo, S. H., Kim, E. H., & Mo, J. (2025) · Inflammation · doi:10.1007/s10753-024-02227-8 · Cited by 7

Human precursor T follicular regulatory cells are primed for differentiation into mature Tfr and disrupted during severe infections

Tulyeu, J., Søndergaard, J. N., Priest, D. G., Ebihara, T., Matsumoto, H., Llamas-Covarrubias, M. A., Imai, M., Esaki, S., Iwasaki, S., Morita, A., et al. (2025) · Science Advances · doi:10.1126/sciadv.adv6939 · Cited by 7

The Antipsychotic Drug Penfluridol Inhibits N-Linked Glycoprotein Processing and Enhances T-cell–Mediated Tumor Immunity

Xu, W., Wang, Y., Zhang, N., Lin, X., Zhu, D., Shen, C., Wang, X., Li, H., Xue, J., Yu, Q., et al. (2023) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-23-0449 · Cited by 7

Dysfunctional regulatory T cell: May be an obstacle to immunotherapy in cardiovascular diseases

Zhang, Y.-S., & Chen, Y. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116359 · Cited by 8

Single-Cell Analysis Uncovers Striking Cellular Heterogeneity of Lung-Infiltrating Regulatory T Cells during Eosinophilic versus Neutrophilic Allergic Airway Inflammation

Iamsawat, S., Yu, R., Kim, S., Dvorina, N., Qiu, K., Choi, J., Baldwin, W. M., & Min, B. (2024) · The Journal of Immunology · doi:10.4049/jimmunol.2300646 · Cited by 7

Discovery of an immunosuppressive functional metabolite from the insect-derived endophytic Aspergillus taichungensis SMU01

Ren, J., Wu, P.-P., Xue, J.-H., Zhao, W., Zhu, Y.-H., Chen, Y., Yang, Q.-J., Luo, Q., Cheng, X., & Bi, E. (2024) · Fitoterapia · doi:10.1016/j.fitote.2024.106007 · Cited by 8

Genetic and Epigenetic Association of FOXP3 with Papillary Thyroid Cancer Predisposition

Achilla, C., Chorti, A. G., Papavramidis, T. S., Angelis, L., & Chatzikyriakidou, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137161 · Cited by 7

Single-Cell Analysis Identifies Distinct Populations of Cytotoxic CD4+ T Cells Linked to the Therapeutic Efficacy of Immune Checkpoint Inhibitors in Metastatic Renal Cell Carcinoma

Yang, X., Wu, J., Fan, L., Chen, B., Zhang, S., & Zheng, W. (2024) · Journal of Inflammation Research · doi:10.2147/jir.s457570 · Cited by 7

Regulatory T cells do not suppress rather activate human basophils by IL-3 and STAT5-dependent mechanisms

Das, M., Victor, E. S., & Bayry, J. (2020) · OncoImmunology · doi:10.1080/2162402x.2020.1773193 · Cited by 7

Antigen-reactive regulatory T cells can be expanded in vitro with monocytes and anti-CD28 and anti-CD154 antibodies

Iwaszkiewicz‐Grześ, D., Gliwiński, M., Eugster, A., Piotrowska, M., Dahl, A., Marek-Trzonkowska, N. M., & Trzonkowski, P. (2020) · Cytotherapy · doi:10.1016/j.jcyt.2020.07.001 · Cited by 7

Antigenic Challenge Influences Epigenetic Changes in Antigen-Specific T Regulatory Cells

Iwaszkiewicz‐Grześ, D., Piotrowska, M., Gliwiński, M., Urban‐Wójciuk, Z., & Trzonkowski, P. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.642678 · Cited by 7

Disproportional enrichment of FoxP3+CD4+ regulatory T cells shapes a suppressive tumour microenvironment in head and neck squamous cell carcinoma

Park, S., Kim, C. G., Kim, D., Hong, M. H., Choi, E. C., Kim, S., Park, Y. M., Kim, J., Yoon, S. O., Kim, G., et al. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.753 · Cited by 7

Role of CNSs Conserved Distal Cis-Regulatory Elements in CD4 + T Cell Development and Differentiation

Long, X., Luo, C., & Zhu, Z. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.919550 · Cited by 7

Increased expression of ST2 on regulatory T cells is associated with cancer associated fibroblast-derived IL-33 in laryngeal cancer

Zhao, Y., Sun, J., Liang, Y., Jiang, X., Tang, X., Sun, Y., Xu, C., Wan, G., Sun, J., & Pan, C. (2022) · Pathology - Research and Practice · doi:10.1016/j.prp.2022.154023 · Cited by 7

Longitudinal monitoring of circulating immune cell phenotypes in large vessel vasculitis

Matsumoto, K., Suzuki, K., Yoshida, H., Magi, M., Kaneko, Y., & Takeuchi, T. (2022) · Autoimmunity Reviews · doi:10.1016/j.autrev.2022.103160 · Cited by 7

Number of FoxP3+ regulatory T-cells are associated with recurrence in vulvar squamous cell carcinoma

Arık, D., Benli, T., & Telli, E. (2022) · Journal of Gynecologic Oncology · doi:10.3802/jgo.2023.34.e16 · Cited by 7

Regulatory T Cells in Pathological Cardiac Hypertrophy: Mechanisms and Therapeutic Potential

Liu, L., Hu, J., Lei, H., Qin, H., Wang, C., Gui, Y., & Xu, D. (2023) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-023-07463-y · Cited by 7

ADENOSINE INFLUENCES FOXP3 EXPRESSION OF TREGS VIA THE A2AR/CREB PATHWAY IN A MOUSE MODEL OF SEPSIS

Zhang, T., Fu, W., Liu, D., He, Y., Wang, J., & Ma, T. (2023) · Shock · doi:10.1097/shk.0000000000002281 · Cited by 7

Current Trends with FOXP3 + Regulatory T Cell Immunotherapy to Contest Autoimmunity and Inflammation

Trinath, J., & Bayry, J. (2019) · Immunotherapy · doi:10.2217/imt-2019-0069 · Cited by 7

Multiply restimulated human cord blood-derived Tregs maintain stabilized phenotype and suppressive function and predict their therapeutic effects on autoimmune diabetes

Bi, Y., Kong, R., Peng, Y., Cai, D., Zhang, Y., Yang, F., Li, X., Deng, W., Liu, F., He, B., et al. (2024) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-024-01277-0 · Cited by 6

Epigenetically Reprogrammed Nanovesicles as Inverse Vaccines for Antigen-Specific Immune Tolerance in Autoimmune Diseases

Xi, Y., Ma, H., Liu, X., Mu, Q., An, X., Li, S., Liang, H., Sun, D., Ma, R., Deng, H., et al. (2025) · Nano Letters · doi:10.1021/acs.nanolett.5c00986 · Cited by 6

Regulatory T Cell in Kidney Transplant: The Future of Cell Therapy?

Matarneh, A. S., Patel, M. A., Parikh, K., Karasinski, A. A., Kaur, G., Shah, V. H., Ghahramani, N., & Trivedi, N. (2025) · Antibodies · doi:10.3390/antib14020049 · Cited by 8

Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes

Zhou, K.-J., Rong, S.-J., Liu, Y.-C., Sun, F., Wang, T., Yu, Q.-L., & Wang, C.-Y. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1740102 · Cited by 7

Targeting the chemokine-Treg axes in tumor immune evasion: from mechanisms to therapeutic opportunities

Lian, C., Liu, L., & Zhang, X. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1779388 · Cited by 6

Approaches for Performance Verification Toward Standardization of Peripheral Blood Regulatory T-Cell Detection by Flow Cytometry

Liu, M., Liu, J.-P., Wang, P., Fu, Y., Zhao, M., Jiang, Y., Zhang, Z., & Shang, H. (2024) · Archives of Pathology & Laboratory Medicine · doi:10.5858/arpa.2023-0284-oa · Cited by 6

The Potential of FOXP3 in Predicting Survival and Treatment Response in Breast Cancer

Liu, L., Xiao, W., Zhang, C., Fan, P., Zeng, J., & Yi, J. (2024) · International Journal of General Medicine · doi:10.2147/ijgm.s454421 · Cited by 6

Density of tumor-infiltrating NK and Treg cells is associated with 5 years progression-free and overall survival in resected lung adenocarcinoma

Szentkereszty, M., Ladányi, A., Gálffy, G., Tóvári, J., & Losonczy, G. (2024) · Lung Cancer · doi:10.1016/j.lungcan.2024.107824 · Cited by 6

In-depth analysis of the interplay between oncogenic mutations and NK cell-mediated cancer surveillance in solid tumors

Pesini, C., Artal, L., Bernal, J. P., Sánchez‐Martínez, D., Pardo, J., & Ramírez-Labrada, A. (2024) · OncoImmunology · doi:10.1080/2162402x.2024.2379062 · Cited by 6

Activation of α2B/2C adrenergic receptor ameliorates ocular surface inflammation through enhancing regulatory T cell function

Fan, N., Yu, M., Wang, S., Blanco, T., Lužnik, Z., Chauhan, S. K., Viswanath, V., Gil, D., Held, K. S., Chen, Y., et al. (2024) · Mucosal Immunology · doi:10.1016/j.mucimm.2024.11.002 · Cited by 6

Immunoglobulin‐like transcript 5 polarizes M2 ‐like tumor‐associated macrophages for immunosuppression in non‐small cell lung cancer

Xu, H., Fu, X., Wang, S., Ge, Y., Zhang, L., Li, J., Zhang, F., Yang, Y., He, Y., Sun, Y., et al. (2025) · International Journal of Cancer · doi:10.1002/ijc.35360 · Cited by 6

Tolerance to 2,4-Dinitrofluorobenzene‒Induced Contact Hypersensitivity Is Mediated by CD73-Expressing Tissue-Homing Regulatory T Cells

Da, M., Chen, L., Enk, A., & Mahnke, K. (2022) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2022.12.003 · Cited by 6

A Novel Prognostic Biomarker CCR8 for Gastric Cancer and Anti-CCR8 Blockade Attenuate the Immunosuppressive Capacity of Tregs In Vitro

Zhang, Z., Wang, G., Shao, X., Wu, H., Su, X., Zhu, L., & Ji, Z. (2023) · Cancer Biotherapy and Radiopharmaceuticals · doi:10.1089/cbr.2022.0095 · Cited by 6

Prenatal cadmium exposure does not induce greater incidence or earlier onset of autoimmunity in the offspring

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