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Contrasting cytotoxic and regulatory T cell responses underlying distinct clinical outcomes to anti-PD-1 plus lenvatinib therapy in cancer

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Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis

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T-Cell Receptor Repertoire Sequencing in the Era of Cancer Immunotherapy

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TCR repertoire profiling revealed antigen-driven CD8+ T cell clonal groups shared in synovial fluid of patients with spondyloarthritis

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Designing meaningful continuous representations of T cell receptor sequences with deep generative models

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Immunotherapy in the Treatment of Urothelial Bladder Cancer: Insights From Single-Cell Analysis

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Geometric network analysis provides prognostic information in patients with high grade serous carcinoma of the ovary treated with immune checkpoint inhibitors

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The role of intestinal flora on tumorigenesis, progression, and the efficacy of PD-1/PD-L1 antibodies in colorectal cancer

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Human thymopoiesis produces polyspecific CD8+ α/β T cells responding to multiple viral antigens

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Immunosequencing identifies signatures of T cell responses for early detection of nasopharyngeal carcinoma

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Modulation of the Immune Environment in Glioblastoma by the Gut Microbiota

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Single B Cell Gene Co-Expression Networks Implicated in Prognosis, Proliferation, and Therapeutic Responses in Non-Small Cell Lung Cancer Bulk Tumors

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Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway

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IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells

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A Microfluidic Approach for Probing Heterogeneity in Cytotoxic T-Cells by Cell Pairing in Hydrogel Droplets

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CD4 + tumor-infiltrating lymphocytes secreting T cell-engagers induce regression of autologous patient-derived non-small cell lung cancer xenografts

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Microorganisms-derived antigens for preventive anti-cancer vaccines

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Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma

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A tumor-binding antibody with cross-reactivity to viral antigens

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Molecular mimicry as a driver of T cell-mediated tumour immunity

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STAG-LLM: Predicting TCR-pHLA binding with protein language models and computationally generated 3D structures

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Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma

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Machine learning and bioinformatics-based insights into the potential targets of saponins in Paris polyphylla smith against non-small cell lung cancer

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Identification of apolipoprotein B–reactive CDR3 motifs allows tracking of atherosclerosis-related memory CD4+T cells in multiple donors

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Premature skewing of T cell receptor clonality and delayed memory expansion in HIV-exposed infants

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The role of reactive enteric glia‐macrophage interactions in acute and chronic inflammation

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T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases

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Immune characteristics associated with lymph node metastasis in early-stage NSCLC

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Fat-to-blood recirculation of partially dysfunctional PD-1+CD4 Tconv cells is associated with dysglycemia in human obesity

Giovenzana, A., Bezzecchi, E., Bichisecchi, A., Cardellini, S., Ragogna, F., Pedica, F., Invernizzi, F., di Filippo, L., Tomajer, V., Aleotti, F., et al. (2024) · iScience · doi:10.1016/j.isci.2024.109032 · Cited by 7 · see citing works

Characterizing the T Cell Repertoire in the Proximal Airway in Health and Disease

Clark, E. A., Talatala, E. R. R., Ye, W., Davis, R. J., Collins, S. L., Hillel, A. T., Ramirez-Solano, M. A., Sheng, Q., Wanjalla, C. N., Mallal, S. A., et al. (2023) · The Laryngoscope · doi:10.1002/lary.31088 · Cited by 7 · see citing works

Expansion kinetics of graft-versus-host T cell clones in patients with post-liver transplant graft-versus-host disease

Li, M., Song, S., Tian, G., Yao, Z., Chen, Y., Huang, H., Jiao, W., Yu, Y., & Lv, G. (2022) · American Journal of Transplantation · doi:10.1111/ajt.17112 · Cited by 6 · see citing works

The Unexpected Benefit of TCR Cross-Reactivity in Cancer Immunotherapy

Bieberich, F., & Reddy, S. T. (2023) · Cancer Research · doi:10.1158/0008-5472.can-23-2594 · Cited by 6 · see citing works

Inferencing Bulk Tumor and Single-Cell Multi-Omics Regulatory Networks for Discovery of Biomarkers and Therapeutic Targets

Ye, Q., & Guo, N. L. (2022) · Cells · doi:10.3390/cells12010101 · Cited by 5 · see citing works

Large-Scale T-cell Receptor Repertoire Profiling Unveils Tumor-Specific Signals for Diagnosing Indeterminate Pulmonary Nodules

Luo, H., Guo, W., Luan, X., Yue, T., Yu, S., Yin, X., Zu, R., Rao, L., Hu, B., Liu, X., et al. (2025) · Cancer Research · doi:10.1158/0008-5472.can-25-1407 · Cited by 5 · see citing works

T-cell receptor determinants of response to chemoradiation in locally-advanced HPV16-driven malignancies

Nenclares, P., Lärkeryd, A., Manodoro, F., Lee, J. Y., Lalondrelle, S., Gilbert, D. C., Punta, M., O’Leary, B., Rullan, A., Sadanandam, A., et al. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2023.1296948 · Cited by 5 · see citing works

Survival prediction and analysis of drug-resistance genes in HER2-positive breast cancer

Yang, L., Chen, S., Wang, M., Peng, S., Zhao, H., Yang, P., Bao, G., & He, X. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e38221 · Cited by 5 · see citing works

Age-dependent cytokine surge in blood precedes cancer diagnosis

Chen, G., Mohsin, A., Zheng, H., Rosenberg‐Hasson, Y., Padilla, C., Sarin, K. Y., Dekker, C. L., Grant, P., Maecker, H. T., Lü, Y., et al. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2420502122 · Cited by 5 · see citing works

Assessing the chronic hepatitis B adaptive immune response by profiling specific T-cell receptor repertoire

Li, X., Zheng, A., Liu, J., Shi, M., Liao, B., Xie, S., Yan, R., Gan, Y., Zuo, X., Gong, M., et al. (2023) · Antiviral Research · doi:10.1016/j.antiviral.2023.105608 · Cited by 5 · see citing works

Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity

Russell, J., Chen, L., Liu, A., Wang, J.-H., Ghosh, S., Zhong, X., Shi, H., Beutler, B., & Nair-Gill, E. (2024) · EMBO Reports · doi:10.1038/s44319-024-00191-w · Cited by 3 · see citing works

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Li, F., Qiao, L., Liang, X., Zhang, Y., Liang, N., Xie, J., Deng, G., Hao, Y., Hu, P., Wu, X., et al. (2026) · Cancer Medicine · doi:10.1002/cam4.71575 · Cited by 4 · see citing works

Immune responses and immunotherapeutic approaches in the treatment against cancer

Leong, S. P. L. (2024) · Clinical & Experimental Metastasis · doi:10.1007/s10585-024-10300-7 · Cited by 4 · see citing works

Proteomic profile of the antibody diversity in circulating extracellular vesicles of lung adenocarcinoma

Huang, X.-F., Xiong, L., Zhang, Y., Peng, X., Ba, H., & Peng, Y. (2024) · Scientific Reports · doi:10.1038/s41598-024-78955-6 · Cited by 4 · see citing works

Identification of novel KRASG12D neoantigen specific TCRs and a strategy to eliminate off-target recognition

Han, X., Han, X., Hao, Y., Wang, B., Luo, L., Chen, S., Zou, L., Huang, J., Chen, T., Wang, W., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06094-1 · Cited by 4 · see citing works

Global analysis of T-cell groups reveals immunological features and common antigen targets of digestive tract tumors

Li, X., Zhang, Y., Guo, S., Wu, Z., Wang, H., Huang, Y., Wang, Y., Qiu, M., Lang, J., Xiao, Y., et al. (2024) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-024-05645-1 · Cited by 4 · see citing works

Five plus Three for the Pancreas

Löhr, M. J., & Pantel, K. (2023) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-22-3977 · Cited by 3 · see citing works

A Decade-Old Atlas of TMEM (Transmembrane) Protein Family in Lung Cancer: Lessons Learnt and Future Directions

Zhang, S., Cao, G., Hu, X., Chen, C., & Chen, P. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27021120 · Cited by 2 · see citing works

mRNA vaccines transform personalized lung cancer treatment

Wei, K., Wan, Z., Wen, M., Xin, S., Zhou, Y., Wei, J. C., Zhu, J., Tang, C., Xiong, Y., Jiang, T., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1707654 · Cited by 2 · see citing works

Tumor-associated bacterial effectors: novel frontiers in tumor biology and immunity

Dai, J.-H., Lu, Y.-Q., Feng, S.-Y., Tan, X.-R., Li, L., Zeng, Y.-C., Chen, J., Ma, J., & Liu, N. (2026) · 中国科学通报：英文版 · doi:10.1016/j.scib.2026.04.034 · Cited by 2 · see citing works

Induction of antigenic immune tolerance to delay type 1 diabetes – challenges for clinical translation

Wesley, J. D., Pagni, P. P., Bergholdt, R., Kreiner, F. F., & von Herrath, M. (2022) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000742 · Cited by 2 · see citing works

Discovery of a novel shared tumor antigen in human lung cancer.

Tseng, D., Chiou, S., Yang, X., Reuben, A., Wilhelmy, J., McSween, A. M., Conley, S. D., Sinha, R., Nabet, B. Y., Wang, C., et al. (2020) · Journal of Clinical Oncology · doi:10.1200/jco.2020.38.15_suppl.3087

Abstract A26: Towards the identification of novel tumor antigens in human lung cancer

Chiou, S., Tseng, D., Yang, X., Reuben, A., McSween, A. M., Wilhelmy, J., Wang, C., Shrager, J. B., Zhang, J., García, K. C., et al. (2020) · Cancer Immunology Research · doi:10.1158/2326-6074.tumimm19-a26

Unveiling cross-reactivity: implications for immune response modulation in cancer

Pretti, M. A. M., Vieira, G. F., Boroni, M., & Bonamino, M. (2024) · Briefings in Bioinformatics · doi:10.1093/bib/bbaf012 · Cited by 2 · see citing works

Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma

Murata, K., Nakatsugawa, M., Rahman, M. A., Nguyen, L. T., Millar, D. G., Mulder, D. T., Sugata, K., Saijo, H., Matsunaga, Y., Kagoya, Y., et al. (2020) · eLife · doi:10.7554/elife.53244 · Cited by 23 · see citing works

A new clustering approach identifies tumor-specific common TCRs with pan-cancer reactivityPreprint

Hennig, S., Gennermann, K., Elezkurtaj, S., Seitz, V., Hirsch, B., Dröge, A., Schaper, S., Bents, D., Eggeling, S., Beushausen, C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.26.650660