Cited by 524Skin Diseases and DiabetesDermatology and Skin DiseasesObesity and Health Practices

The DOI matches its Crossref record; 218 of the 226 references it cites were found in a registry or an index.

Obesity and the skin: Skin physiology and skin manifestations of obesity

Yosipovitch, Gil, DeVore, Amy, Dawn, Aerlyn·2007·Journal of the American Academy of Dermatology

Abstract

Unlabelled Obesity is widely recognized as an epidemic in the Western world; however, the impact of obesity on the skin has received minimal attention. The purpose of this article is to highlight the association between obesity and dermatologic conditions. We review the impact of obesity on the skin, including skin physiology, skin manifestations of obesity, and dermatologic diseases aggravated by obesity. Obesity is responsible for changes in skin barrier function, sebaceous glands and sebum production, sweat glands, lymphatics, collagen structure and function, wound healing, microcirculation and macrocirculation, and subcutaneous fat. Moreover, obesity is implicated in a wide spectrum of dermatologic diseases, including acanthosis nigricans, acrochordons, keratosis pilaris, hyperandrogenism and hirsutism, striae distensae, adiposis dolorosa, and fat redistribution, lymphedema, chronic venous insufficiency, plantar hyperkeratosis, cellulitis, skin infections, hidradenitis suppurativa, psoriasis, insulin resistance syndrome, and tophaceous gout. We review the clinical features, evidence for association with obesity, and management of these various dermatoses and highlight the profound impact of obesity in clinical dermatology.Learning objective After completing this learning activity, participants should be aware of obesity-associated changes in skin physiology, skin manifestations of obesity, and dermatologic diseases aggravated by obesity, and be able to formulate a pathophysiology-based treatment strategy for obesity-associated dermatoses.

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Crossref · 10.1016/j.jaad.2006.12.004

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218 of 218 references verified0 citation errors · 0 not checkable

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Research works printed but not linked: 2

  1. Commons, 2001, Large-volume liposuction: a review of 631 consecutive cases over 12 years, Plast Reconstr Surg, 108, 1753, 10.1097/00006534-200111000-00051 · DOI
  2. Giese, 2001, Improvements in cardiovascular risk profile with large-volume liposuction: a pilot study, Plast Reconstr Surg, 108, 510, 10.1097/00006534-200108000-00036 · DOI

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Metadata

Authors
Yosipovitch, G., DeVore, A., & Dawn, A.
Affiliations
Wake Forest University Health Sciences (US)
Corresponding author
Yosipovitch, Gil
Venue
Journal of the American Academy of Dermatology
Publisher
Elsevier BV
Published
2007-06
Volume
56
Issue
6
Pages
901-916
ISSN
0190-9622 (ISSN-L)
OpenAlex
W2009476361
Cited by
524
References
226
Citations by year
2026: 17 · 2025: 19 · 2024: 22 · 2023: 29 · 2022: 19 · 2021: 29 · 2020: 34 · 2019: 30 · 2018: 32 · 2017: 32 · 2016: 32 · 2015: 29 · 2014: 32 · 2013: 36 · 2012: 24
FWCI
4.68
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of the American Academy of Dermatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Skin Diseases and Diabetes
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity and Health Practices
Keywords
obesity, skin barrier function, sebum production, sweat glands, collagen, wound healing, subcutaneous adipose tissue, acanthosis nigricans, acrochordons, keratosis pilaris, hyperandrogenism, hirsutism, striae, adiposis dolorosa, lymphedema, chronic venous insufficiency, plantar hyperkeratosis, cellulitis, skin infections, hidradenitis suppurativa, psoriasis, metabolic syndrome, tophaceous gout
MeSH terms
Acanthosis Nigricans, Adiposis Dolorosa, Animals, Chronic Disease, Elasticity, Humans, Insulin Resistance, Intertrigo, Lymphedema, Microcirculation, Obesity, Pro-Opiomelanocortin, Psoriasis, Sebaceous Glands, Skin Diseases, Venous Insufficiency, Comorbidity, Hidradenitis Suppurativa, Fasciitis, Necrotizing

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