Multimorbidity in Older Adults With Cardiovascular Disease
Open accessAbstract
Multimorbidity occurs in adults of all ages, but the number and complexity of comorbid conditions commonly increase with advancing age such that cardiovascular disease (CVD) in older adults typically occurs in a context of multimorbidity. Current clinical practice and research mainly target single disease-specific care that does not embrace the complexities imposed by concurrent conditions. In this paper, emerging concepts regarding CVD in combination with multimorbidity are reviewed, including recommendations for incorporating multimorbidity into clinical decision making, critical knowledge gaps, and research priorities to optimize care of complex older patients.
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Patients with cardiovascular disease tend to have greater multimorbidity than individuals without CVD.
“Patients with CVD tend to have greater multimorbidity than individuals who are free from CVD”
From Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty (2018) · cites this paper as [195]
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Vanassche, T., Verhamme, P. B., Anand, S. S., Shestakovska, O., Leong, D. P., Fox, K. A. A., Bhatt, D. L., Avezum, Á., Alings, M., Aboyans, V., et al. (2021) · European Heart Journal - Cardiovascular Pharmacotherapy · doi:10.1093/ehjcvp/pvab050 · Cited by 18 · see citing works
Hu, X., Li, S., Wei, Z., Wu, D., Meng, L., Li, J., Xu, J., Zhang, L., Ma, Q., Li, H., et al. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1349418 · Cited by 17 · see citing works
- Authors
- Forman, D. E., Maurer, M. S., Boyd, C., Brindis, R., Salive, M. E., Horne, F. M., Bell, S. P., Fulmer, T., Reuben, D. B., Zieman, S., & Rich, M. W.
- Affiliations
- University of Pittsburgh (US)
- Columbia University Irving Medical Center (US)
- Johns Hopkins University (US)
- University of California, San Francisco (US)
- National Institutes of Health (US)
- Vanderbilt University Medical Center (US)
- John A. Hartford Foundation (US)
- University of California, Los Angeles (US)
- Washington University in St. Louis (US)
- Corresponding author
- Forman, Daniel E.
- ORCID
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2018-05
- Volume
- 71
- Issue
- 19
- Pages
- 2149-2161
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC6028235
- OpenAlex
- W2800121660
- Cited by
- 484
- References
- 75
- Citations by year
- 2026: 75 · 2025: 98 · 2024: 76 · 2023: 59 · 2022: 51 · 2021: 57 · 2020: 37 · 2019: 18 · 2018: 13
- FWCI
- 4.47
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Hartford Foundation for Public Giving
- Pfizer
- Patient-Centered Outcomes Research Institute
- Alnylam Pharmaceuticals
- Prothena
- National Institute on Aging (AG 024827, U13AG047008, K24AG036778, R56AG051637, P30AG024827)
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- multimorbidity, cardiovascular disease, older adults, comorbidities, clinical decision-making, geriatric cardiology, research priorities
- MeSH terms
- Clinical Decision-Making, Multimorbidity, Age Factors, Aged, Aged, 80 and over, Aging, Mental Disorders, Cardiovascular Diseases, Humans, Kidney Diseases
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