The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
Effects of Experimental Sleep Restriction on Energy Intake, Energy Expenditure, and Visceral Obesity
Open accessAbstract
Background Although the consequences of sleep deficiency for obesity risk are increasingly apparent, experimental evidence is limited and there are no studies on body fat distribution.Objectives The purpose of this study was to investigate the effects of experimentally-induced sleep curtailment in the setting of free access to food on energy intake, energy expenditure, and regional body composition.Methods Twelve healthy, nonobese individuals (9 males, age range 19 to 39 years) completed a randomized, controlled, crossover, 21-day inpatient study comprising 4 days of acclimation, 14 days of experimental sleep restriction (4 hour sleep opportunity) or control sleep (9 hour sleep opportunity), and a 3-day recovery segment. Repeated measures of energy intake, energy expenditure, body weight, body composition, fat distribution and circulating biomarkers were acquired.Results With sleep restriction vs control, participants consumed more calories (P = 0.015), increasing protein (P = 0.050) and fat intake (P = 0.046). Energy expenditure was unchanged (all P > 0.16). Participants gained significantly more weight when exposed to experimental sleep restriction than during control sleep (P = 0.008). While changes in total body fat did not differ between conditions (P = 0.710), total abdominal fat increased only during sleep restriction (P = 0.011), with significant increases evident in both subcutaneous and visceral abdominal fat depots (P = 0.047 and P = 0.042, respectively).Conclusions Sleep restriction combined with ad libitum food promotes excess energy intake without varying energy expenditure. Weight gain and particularly central accumulation of fat indicate that sleep loss predisposes to abdominal visceral obesity. (Sleep Restriction and Obesity; NCT01580761).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Covassin et al. 114 reported that 21-day of experimental sleep restriction using a 4-h sleep opportunity promoted the consumption of an additional ~310 kcals per day”
From The effects of sleep disruption on metabolism, hunger, and satiety, and the influence of psychosocial stress and exercise: A narrative review (2024) · cites this paper as [114]
In the citing paper
“and an 11% increase in abdominal visceral adiposity”
From The effects of sleep disruption on metabolism, hunger, and satiety, and the influence of psychosocial stress and exercise: A narrative review (2024) · cites this paper as [114]
In the citing paper
“and a 0.5 kg increase in body weight when compared to the control 9-h sleep opportunity condition in healthy young adults.”
From The effects of sleep disruption on metabolism, hunger, and satiety, and the influence of psychosocial stress and exercise: A narrative review (2024) · cites this paper as [114]
In the citing paper
“Sleep deprivation significantly promotes excess energy intake and visceral obesity.30”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Pathophysiology of human visceral obesity: an update
Tchernof, A., & Després, J.-P. (2013) · Physiological Reviews · doi:10.1152/physrev.00033.2011 · Cited by 2,583
Subcutaneous and visceral adipose tissue: Structural and functional differences
Ibrahim, M. M. (2010) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00623.x · Cited by 2,238
Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk
Meier-Ewert, H. K., Ridker, P. M., Rifai, N., Regan, M. M., Price, N. J., Dinges, D. F., & Mullington, J. M. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.07.050 · Cited by 1,195
St-Onge, M.-P., Grandner, M. A., Brown, D., Conroy, M. B., Jean-Louis, G., Coons, M., & Bhatt, D. L. (2016) · Circulation · doi:10.1161/cir.0000000000000444 · Cited by 1,044
Spiegel, K., Leproult, R., L’Hermite-Balériaux, M., Copinschi, G., Penev, P. D., & Van Cauter, E. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1003 · Cited by 1,006
Prevalence of healthy sleep duration among adults – United States, 2014
Liu, Y., Wheaton, A. G., Chapman, D. P., Cunningham, T. J., Lu, H., & Croft, J. B. (2016) · MMWR. Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6506a1 · Cited by 914
Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain
Markwald, R. R., Melanson, E. L., Smith, M. R., Higgins, J., Perreault, L., Eckel, R. H., & Wright, K. P. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1216951110 · Cited by 810
Yin, J., Jin, X., Shan, Z., Li, S., Huang, H., Li, P., Peng, X., Peng, Z., Yu, K., Bao, W., et al. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.005947 · Cited by 721
Sleep curtailment is accompanied by increased intake of calories from snacks
Nedeltcheva, A. V., Kilkus, J. M., Imperial, J., Kasza, K., Schoeller, D. A., & Penev, P. D. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26574 · Cited by 717
Body Fat Distribution, Incident Cardiovascular Disease, Cancer, and All-Cause Mortality
Britton, K. A., Massaro, J. M., Murabito, J. M., Kreger, B. E., Hoffmann, U., & Fox, C. S. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.06.027 · Cited by 687
Cited by
Sorted by citations
Sleep physiology, pathophysiology, and sleep hygiene
Baranwal, N., Yu, P. K., & Siegel, N. S. (2023) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2023.02.005 · Cited by 540
Zhou, X., Cai, J., Targher, G., Byrne, C. D., Shapiro, M. D., Sung, K., Somers, V. K., Chahal, C. A. A., George, J., Chen, L., et al. (2022) · Cardiovascular Diabetology · doi:10.1186/s12933-022-01697-0 · Cited by 174
Self-citationLiang, Y. Y., Feng, H., Chen, Y., Jin, X., Xue, H., Zhou, M., Ma, H., Ai, S., Wing, Y.-K., Geng, Q., et al. (2023) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwad060 · Cited by 102
Obstructive Sleep Apnea and Cardiometabolic Disease: Obesity, Hypertension, and Diabetes
Tasali, E., Pamidi, S., Covassin, N., & Somers, V. K. (2025) · Circulation Research · doi:10.1161/circresaha.125.325676 · Cited by 108
Self-citationThe interrelationship between sleep, diet, and glucose metabolism
St-Onge, M.-P., Cherta-Murillo, A., Darimont, C., Mantantzis, K., Martin, F. P., & Owen, L. (2023) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2023.101788 · Cited by 79
Metadata
- Authors
- Covassin, N., Singh, P., McCrady-Spitzer, S. K., St Louis, E. K., Calvin, A. D., Levine, J. A., & Somers, V. K.
- Affiliations
- Mayo Clinic (US)
- Pennington Biomedical Research Center (US)
- Mayo Clinic Health System (US)
- Corresponding author
- Somers, Virend K.
- ORCID
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2022-04
- Volume
- 79
- Issue
- 13
- Pages
- 1254-1265
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC9187217
- OpenAlex
- W4226265771
- Cited by
- 125
- References
- 44
- Citations by year
- 2026: 32 · 2025: 30 · 2024: 22 · 2023: 28 · 2022: 13
- FWCI
- 21.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Civil War Book Review (submittedVersion)
- Funders
- National Institutes of Health (UL1TR002377)
- National Heart, Lung, and Blood Institute (R01HL114024)
- National Center for Advancing Translational Sciences
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- sleep restriction, sleep deprivation, energy intake, energy expenditure, visceral obesity, abdominal fat, body composition, weight gain, protein intake, dietary fat intake, obesity risk
- MeSH terms
- Adult, Energy Intake, Energy Metabolism, Humans, Male, Obesity, Sleep, Young Adult, Obesity, Abdominal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
