Childhood abuse in late-life depression
Open accessAbstract
Background Little is known about the role of childhood abuse in late-life depression. The aim of the study is therefore to study whether childhood abuse is associated with late-life depression according to its onset, and which clinical characteristics play a role in this association.Methods Data were used from 378 depressed and 132 non-depressed persons, aged 60-93 years, from the Netherlands Study of Depression in Older persons (NESDO). Childhood abuse included psychological, physical and sexual abuse and emotional neglect.Results 53% of the depressed older adults reported childhood abuse, compared to 16% of the non-depressed older adults (p<0.001). Using logistic regression analyses adjusted for age, sex and level of education, depression was strongest associated with physical abuse (Odds Ratio ((OR) 13.71; 95% Confidence Interval (CI) 3.25-57.91) and least with sexual abuse (OR 5.35; 95% CI 2.36-12.14). Childhood abuse was associated with early-onset (OR 13.73, 95% CI 7.31-25.80), middle age-onset (OR 5.36, 95% CI 2.90-9.90) and late-onset depression (OR 4.74, 95% CI 2.51-8.95). In the late-onset group childhood abuse was associated with an increased number of chronic diseases.Limitations Age of depression onset and childhood abuse were asked retrospectively, which may have biased the results.Conclusions Childhood abuse is strongly related to late-life depression and its comorbidities, even in the case of late-onset depression. This might suggest that psychological wellbeing can be maintained throughout middle age, but may be disturbed in later life.
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- Authors
- Comijs, H. C., van Exel, E., van der Mast, R. C., Paauw, A., Oude Voshaar, R., & Stek, M. L.
- Affiliations
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- GGZ inGeest (NL)
- Corresponding author
- Comijs, Hannie C.
- ORCID
- Comijs, Hannie C.
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2013-05
- Volume
- 147
- Issue
- 1-3
- Pages
- 241-246
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2054158871
- Cited by
- 123
- References
- 52
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 13 · 2023: 13 · 2022: 17 · 2021: 11 · 2020: 10 · 2019: 10 · 2018: 9 · 2017: 6 · 2016: 5 · 2015: 5 · 2014: 5 · 2013: 2
- FWCI
- 4.36
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- Universiteit Leiden
- Radboud Universiteit
- Vrije Universiteit Amsterdam
- Fonds NutsOhra
- GGZ inGeest
- Rivierduinen
- Leids Universitair Medisch Centrum
- Universitair Medisch Centrum Groningen
- Radboud Universitair Medisch Centrum
- Stichting tot Steun Vereniging tot Christelijke Verzorging van Geestes- en Zenuwzieken
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Demography › Elder Abuse and Neglect
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- childhood abuse, geriatric depression, older adults, physical abuse, sexual abuse, psychological violence, emotional neglect, depression onset, chronic comorbidities, psychological well-being
- MeSH terms
- Aged, Aged, 80 and over, Child, Child Abuse, Depression, Depressive Disorder, Female, Humans, Male, Middle Aged, Netherlands, Retrospective Studies, Adult Survivors of Child Abuse
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