Effectiveness and adherence of telephone-administered psychotherapy for depression: A systematic review and meta-analysis
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Background The aim of this systematic review was to evaluate the effectiveness of telephone-administered psychotherapy for depression in adults when compared to control conditions or other active treatments, and to determine adherence to telephone-administered psychotherapy.Methods A bibliographic search was conducted in MEDLINE, Embase, PsycINFO, the Cochrane library, and a number of sources of grey literature. We included randomised controlled trials (RCTs) examining the impact of telephone-administered psychotherapy on depressive symptomatology. Two reviewers independently screened citations, extracted the relevant data, and assessed risk of bias using Cochrane tools. Random effects meta-analyses were used to determine the average effect of the interventions on depressive symptomatology: main analysis including randomised trials only, and several exploratory subgroup and sensitivity analyses.Results We identified ten trials. Telephone-administered psychotherapy showed beneficial effects on depression severity when compared to control conditions ((standardized mean difference [SMD]= -0.85 (95% CI -1.56 to -0.15)). When compared to active comparators, the meta-analysis showed a non-significant small effect size (SMD= -0.18 (95% CI -0.45 to 0.09)), in favour of telephone-administered psychotherapy. Total weighted mean adherence was 73%.Limitations Some of the included studies presented a small sample size. Due to variations in time points follow-ups among the studies, it was not possible to determine long term post intervention effects.Conclusions Available evidence suggests that telephone-delivered psychotherapy may be an effective strategy to reduce depression symptoms when compared to control conditions, and shows an adequate treatment adherence. Future research is needed to determine its cost-effectiveness and long-term effects.
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Telephone-delivered psychotherapy for depression has comparative effectiveness to face-to-face treatment.
“A recent systematic review and meta-analysis of telephone delivered psychotherapy for depression highlighted adequate treatment adherence, beneficial effects when compared with usual care, and comparative effectiveness to face-to-face treatment [13].”
From 'I didn't know what to expect': Exploring patient perspectives to identify targets for change to improve telephone-delivered psychological interventions (2020) · cites this paper as [13]
Section 3.5.2 reports no statistically significant difference between telephone psychotherapy and a pooled group of active comparators, four of which were face-to-face interventions. The Implications section says there is no evidence that telephone treatment is less effective than active comparators, but the Discussion cautions that these comparisons are less conclusive; the review does not establish equivalent effectiveness specifically to face-to-face treatment. Page numbers were not available in our copy. (LLM, conf=0.82)
Experimental — accuracy not yet measuredEvidence for clinical effectiveness and acceptability of the telephone as a mode of treatment has been established, but challenges remain around uptake and engagement.
“The evidence for clinical effectiveness and acceptability of the telephone as a mode of treatment has been established [13, 30]; challenges, however, remain around uptake and engagement.”
From 'I didn't know what to expect': Exploring patient perspectives to identify targets for change to improve telephone-delivered psychological interventions (2020) · cites this paper as [13]
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- Authors
- Castro, A., Gili, M., Ricci-Cabello, I., Roca, M., Gilbody, S., Perez-Ara, M. Á., Seguí, A., & McMillan, D.
- Affiliations
- Health Research Institute of the Balearic Islands (ES)
- Red de Investigación en Actividades Preventivas y Promoción de la Salud (ES)
- University of York (GB)
- Universitat de les Illes Balears (ES)
- Corresponding author
- Castro, Adoración
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 260
- Pages
- 514-526
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2971782318
- Cited by
- 78
- References
- 52
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 7 · 2023: 12 · 2022: 19 · 2021: 16 · 2020: 14
- FWCI
- 1.73
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion, other-oa)
- Docusalut (Conselleria de Salut i Consum del Govern de les Illes Balears) (submittedVersion, cc-by-nc-nd)
- Hispana (submittedVersion, cc-by-nc-nd)
- Funders
- Universitat de les Illes Balears
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- depression, medication adherence, depression severity, treatment effectiveness, adults
- MeSH terms
- Adult, Depression, Humans, Psychotherapy, Telephone, Young Adult
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