Cited by 30Child and Adolescent Psychosocial and Emotional DevelopmentBullying, Victimization, and AggressionHealth disparities and outcomes

The association between the social environment of childhood and adolescence and depression in young adulthood - A prospective cohort study

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Kehusmaa, Johanna, Ruotsalainen, Heidi, Männikkö, Niko, Alakokkare, Anni-Emilia, Niemelä, Mika, Jääskeläinen, Erika, Miettunen, Jouko·2022·Journal of Affective Disorders

Abstract

BACKGROUND: Good social relationships with parents and peers protect children and adolescents from developing mental disorders in adulthood while several negative experiences increase the risk of depression in later life. METHODS: We used population-based cohort data from the Northern Finland Birth Cohort (NFBC) 1986. Participants (n = 6147), their teachers and parents reported factors associated with the social environment of children and adolescents. Diagnoses of depression of cohort members were derived from Finnish nationwide registers. We conducted regression analyses to assess which factors of the social environment of childhood and adolescence were associated with depression in young adulthood. RESULTS: Bullying victimization in adolescence was the strongest predictor of depression in young adulthood among girls (OR 2.23: 95% CI 1.47-3.39) and boys (OR 2.44: 95% CI 1.49-4.00). Loneliness and bullying behavior in childhood were associated with depression in boys only. Loneliness in adolescence (OR 1.63: 95% CI 1.30-2.04) was associated with depression among both genders. Spending with the family seemed to protect against the negative impact of bullying and loneliness. LIMITATIONS: We used single-item study questions to measure social relationships. These questions do not necessarily describe the phenomena as accurately as the measures validated for them. CONCLUSION: Problems in social relationships with peers in childhood and adolescence are associated with depression in young adulthood. Time spent with the family is emphasized in situations in which adolescents have problems in peer-relationships.

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  • There remains a gap in understanding the long-term effects of loneliness on mental health into adulthood.

    “While previous research has established the link between loneliness and mental health problems [16–18], there remains a gap in understanding the long-term effects of loneliness on mental health into adulthood [19].”

    From The prospective association of adolescent loneliness and low resilience with anxiety and depression in young adulthood: The HUNT study (2025) · cites this paper as [19]

    Section 4.2 says there has been a lack of studies on childhood loneliness and depression in young adulthood, particularly regarding gender differences. That supports a gap in knowledge about a long-term association, but the cited passage concerns depression specifically, not mental health outcomes broadly. (LLM, conf=0.83)

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  • Our findings align with studies by Kehusmaa et al. and Xerxa et al., linking childhood and adolescent loneliness with anxiety and depression in young adulthood.

    “Our findings align with studies by Kehusmaa et al. [29] and Xerxa et al. [30], linking childhood and adolescent loneliness with anxiety and depression in young adulthood.”

    From The prospective association of adolescent loneliness and low resilience with anxiety and depression in young adulthood: The HUNT study (2025) · cites this paper as [29]

    Section 4.2 reports that childhood loneliness was associated with depression in young adulthood only among boys, while adolescent loneliness was associated with depression in both genders. It does not report an association with anxiety in young adulthood; it mentions anxiety only as a possible mechanism that may increase depression risk. Page numbers were not provided in our copy. (LLM, conf=0.90)

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4 of the 60 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. GBD 2017, 2018. Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 392 (10159), 1789-1858. https://doi.org/10.1016/S0140-6736(18)32279-7. · DOI · Paper page
  2. Malik, F., Marwaha, R., 2020. Developmental stages of social emotional development. Available from. In: StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL). https://www.ncbi.nlm.nih.gov/books/NBK534819/.
  3. Moisio, P., Rämö, T., 2007. Koettu yksinäisyys demografisten ja sosioekonomisten taustatekijöiden mukaan Suomessa vuosina 1994 ja 2006 [Experienced Loneliness According to Demographic and Socioeconomical Background Factors in Finland in 1994 and 2006]. Yhteiskuntapolitiikka 72 (4), 392-401. https://www.julkari.fi/bits tream/handle/10024/100808/074moisio.pdf?sequence=1.
  4. Wasserman, D., 2011. Psychological theories of depression. In: Wasserman, D. (Ed.), Depression, 2nd ed. OUP, Oxford.

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Authors
Kehusmaa, J., Ruotsalainen, H., Männikkö, N., Alakokkare, A.-E., Niemelä, M., Jääskeläinen, E., & Miettunen, J.
Affiliations
  • Oulu University Hospital (FI)
  • Oulu University of Applied Sciences (FI)
Corresponding author
Kehusmaa, Johanna
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2022-05
Volume
305
Pages
37-46
ISSN
0165-0327 (ISSN-L)
OpenAlex
W4214767966
Cited by
30
References
60
Citations by year
2026: 6 · 2025: 8 · 2024: 8 · 2023: 6 · 2022: 2
FWCI
5.49
Type
journal article
Language
en
Open access
Locations
  • Journal of Affective Disorders (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • Juho Vainio Fundation (202100430)
  • Yrjö Jahnssonin Säätiö
  • National Institutes of Health (2000 G DF682, 50945)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Psychology › Social Psychology › Bullying, Victimization, and Aggression
  • Social Sciences › Health › Health disparities and outcomes
Keywords
bullying victimization, loneliness, peer relationships, family time, parent-adolescent relationships, sex differences, Northern Finland Birth Cohort 1986
MeSH terms
Adolescent, Adult, Child, Female, Humans, Longitudinal Studies, Male, Prospective Studies, Social Environment, Cohort Studies, Crime Victims, Young Adult, Bullying

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